Search filters

List of works by Stefano Gianni

A Carboxylate to Amide Substitution That Switches Protein Folds

scientific article published on 28 August 2018

A PDZ domain recapitulates a unifying mechanism for protein folding

scholarly article

A common folding mechanism in the cytochrome c family

scientific article published in October 2004

A complex equilibrium among partially unfolded conformations in monomeric transthyretin

scientific article published in July 2014

A conserved folding mechanism for PDZ domains

scientific article

A conserved hydrogen-bond network stabilizes the structure of Beta class glutathione S-transferases.

scientific article published on 14 March 2009

A folding-after-binding mechanism describes the recognition between the transactivation domain of c-Myb and the KIX domain of the CREB-binding protein

scientific article

A sequential binding mechanism in a PDZ domain.

scientific article

A strategic protein in cytochrome c maturation: three-dimensional structure of CcmH and binding to apocytochrome c

scientific article

Agitation and high ionic strength induce amyloidogenesis of a folded PDZ domain in native conditions.

scientific article

An Obligatory Intermediate in the Folding Pathway of Cytochromec552fromHydrogenobacter thermophilus

scientific article published in Journal of Biological Chemistry

An On-pathway Intermediate in the Folding of a PDZ Domain

scientific article published in Journal of Biological Chemistry

Analyzing the Folding and Binding Steps of an Intrinsically Disordered Protein by Protein Engineering

scientific article

Azole drugs trap cytochrome P450 EryK in alternative conformational states

scientific article

Comparing the binding properties of peptides mimicking the Envelope protein of SARS-CoV and SARS-CoV-2 to the PDZ domain of the tight junction-associated PALS1 protein

scientific article published on 21 August 2020

Comparison of successive transition states for folding reveals alternative early folding pathways of two homologous proteins

scientific article

Conserved nucleation sites reinforce the significance of Phi value analysis in protein-folding studies

scientific article published on 18 July 2014

Cytochrome c(551) as a model system for protein folding.

scientific article published in January 2003

Deciphering the folding transition state structure and denatured state properties of nucleophosmin C-terminal domain

scientific article

Demonstration by burst-phase analysis of a robust folding intermediate in the FF domain

scientific article published on 31 January 2008

Demonstration of a folding after binding mechanism in the recognition between the measles virus NTAIL and X domains

scientific article published on 22 December 2014

Demonstration of a low-energy on-pathway intermediate in a fast-folding protein by kinetics, protein engineering, and simulation

scientific article

Demonstration of long-range interactions in a PDZ domain by NMR, kinetics, and protein engineering

scientific article

Distinguishing between smooth and rough free energy barriers in protein folding.

scientific article

Distinguishing induced fit from conformational selection

scientific article

Energetic pathway sampling in a protein interaction domain.

scientific article

Engineered Symmetric Connectivity of Secondary Structure Elements Highlights Malleability of Protein Folding Pathways

scientific article published in 2009

Engineering a switchable toxin: the potential use of PDZ domains in the expression, targeting and activation of modified saporin variants

scientific article

Exploring the cytochrome c folding mechanism: cytochrome c552 from thermus thermophilus folds through an on-pathway intermediate

scientific article published on 2 July 2003

Fast coordination changes in cytochrome c do not necessarily imply folding

scientific article published on 3 August 2001

Fast folding kinetics and stabilization of apo-cytochrome c

scholarly article by Alessandro Borgia published in February 2008

Folding Mechanism of the SH3 Domain from Grb2

scientific article published on 23 August 2018

Folding and misfolding in a naturally occurring circularly permuted PDZ domain

scientific article published on 7 February 2008

Folding mechanism of the C-terminal domain of nucleophosmin: residual structure in the denatured state and its pathophysiological significance

scientific article

Folding pathways of proteins with increasing degree of sequence identities but different structure and function

scientific article

Frustration Sculpts the Early Stages of Protein Folding.

scientific article published on 23 July 2015

GA/GB Fold switching may modulate fatty acid transfer from human serum albumin to bacteria

scientific article published on 01 November 2012

GB1 is not a two-state folder: identification and characterization of an on-pathway intermediate

scientific article

Identification and characterization of protein folding intermediates

scientific article published on 24 April 2007

Interactions outside the boundaries of the canonical binding groove of a PDZ domain influence ligand binding.

scientific article published on 23 October 2012

Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate.

scientific article

Kinetic folding mechanism of PDZ2 from PTP-BL.

scientific article published on 25 July 2005

Ligand binding by PDZ domains.

scientific article published on 07 June 2012

Mechanism of Folding and Binding of the N-Terminal SH2 Domain from SHP2

scientific article published on 07 August 2018

Mechanism of Na(+) binding to thrombin resolved by ultra-rapid kinetics.

scientific article published on 29 September 2007

Mechanisms of protein folding

Morphogenesis of a protein: folding pathways and the energy landscape

scientific article published on April 2012

Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases ⬇️

scientific article published on December 5, 2011

Parallel pathways in cytochrome c(551) folding.

scientific article

Plasticity of the protein folding landscape: switching between on- and off-pathway intermediates

scientific article published on 26 June 2007

Probing the role of backbone hydrogen bonds in protein-peptide interactions by amide-to-ester mutations

scientific article published on 7 June 2013

Reassessing the folding of the KIX domain: evidence for a two-state mechanism

scientific article published on 9 October 2012

Refolding kinetics of cytochrome c(551) reveals a mechanistic difference between urea and guanidine

scientific article

Role of Ser 11 in the stabilization of the structure of Ochrobactrum anthropi glutathione transferase

scientific article

Sequence-specific long range networks in PSD-95/discs large/ZO-1 (PDZ) domains tune their binding selectivity

scientific article published on 8 June 2011

Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains.

scientific article

Simulation and experiment conspire to reveal cryptic intermediates and a slide from the nucleation-condensation to framework mechanism of folding

scientific article published in July 2005

Snapshots of protein folding. A study on the multiple transition state pathway of cytochrome c(551) from Pseudomonas aeruginosa

scientific article published in June 2001

Structural and functional characterization of CcmG from Pseudomonas aeruginosa, a key component of the bacterial cytochrome c maturation apparatus

scientific article

Structural characterization of a misfolded intermediate populated during the folding process of a PDZ domain

article published in 2010

Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system

scientific article published on 26 August 2013

The Folding Pathway of the KIX Domain.

scientific article published on May 2017

The Plastic Energy Landscape of Protein Folding: A TRIANGULAR FOLDING MECHANISM WITH AN EQUILIBRIUM INTERMEDIATE FOR A SMALL PROTEIN DOMAIN

scientific article

The binding mechanisms of intrinsically disordered proteins.

scientific article

The denatured state dictates the topology of two proteins with almost identical sequence but different native structure and function

scientific article

The folding pathway of a functionally competent C-terminal domain of nucleophosmin: protein stability and denatured state residual structure

scientific article published on 22 April 2013

The folding pathway of an engineered circularly permuted PDZ domain

scientific article published on 5 January 2008

The folding process of acylphosphatase from Escherichia coli is remarkably accelerated by the presence of a disulfide bond.

scientific article published on 30 April 2008

The kinetic pathway of folding of barnase

scientific article

The kinetics of PDZ domain-ligand interactions and implications for the binding mechanism

scientific article published on 27 July 2005

The kinetics of folding of frataxin

The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c-Myb

scientific article published on 9 May 2014

The mechanism of binding of the second PDZ domain from the Protein Tyrosine Phosphatase-BL to the Adenomatous Polyposis Coli tumor suppressor.

scientific article

The structure of the major transition state for folding of an FF domain from experiment and simulation

scientific article published in July 2005

Tolerance of Protein Folding to a Circular Permutation in a PDZ Domain

scientific article

Two conserved residues govern the salt and pH dependencies of the binding reaction of a PDZ domain

scientific article published on 2 October 2006

Understanding Intramolecular Crosstalk in an Intrinsically Disordered Protein

scientific article published on 12 February 2019

Understanding the effect of alternative splicing in the folding and function of the second PDZ from protein tyrosine phosphatase-BL.

scientific article published on 19 March 2015

Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein

scientific article

Unifying features in protein-folding mechanisms

scientific article published on 31 October 2003

Paulina is supported by:

About Paulina

Help