List of works - Alexander Bershadsky

A mechano-signalling network linking microtubules, myosin IIA filaments and integrin-based adhesions

scientific article published on 21 May 2019

A new dimension in retrograde flow: centripetal movement of engulfed particles.

scientific article

A novel mechanism of actin filament processive capping by formin: solution of the rotation paradox.

scientific article

Actin cytoskeleton of spread fibroblasts appears to assemble at the cell edges

scientific article published on 01 June 1986

Actomyosin-generated tension controls the molecular kinetics of focal adhesions.

scientific article published on 12 April 2011

Adhesion-dependent cell mechanosensitivity.

scientific article published on January 2003

Adhesion-mediated mechanosensitivity: a time to experiment, and a time to theorize.

scientific article published on 22 August 2006

Allicin inhibits cell polarization, migration and division via its direct effect on microtubules.

scientific article published on May 2007

Analysis of the local organization and dynamics of cellular actin networks

scientific article

Assembly and mechanosensory function of focal adhesions: experiments and models.

scientific article

Association of intermediate filaments with vinculin-containing adhesion plaques of fibroblasts

scientific article published on 01 January 1987

Cadherin-mediated regulation of microtubule dynamics

article

Calculation of forces at focal adhesions from elastic substrate data: the effect of localized force and the need for regularization

scientific article

Caldesmon transgene expression disrupts focal adhesions in HTM cells and increases outflow facility in organ-cultured human and monkey anterior segments.

scientific article published on 26 January 2006

Cellular chirality arising from the self-organization of the actin cytoskeleton.

scientific article

Cellular contractility requires ubiquitin mediated proteolysis

scientific article

Comparative dynamics of retrograde actin flow and focal adhesions: formation of nascent adhesions triggers transition from fast to slow flow

scientific article (publication date: 2008)

Cortactin releases the brakes in actin- based motility by enhancing WASP-VCA detachment from Arp2/3 branches.

scientific article

Crawling cell locomotion revisited

scientific article published on 9 December 2011

Cytoskeleton of mouse embryo fibroblasts. Electron microscopy of platinum replicas

scientific article published on 01 May 1984

Cytoskeleton of rat neoplastic cells of spontaneous origin and their derivatives after supertransformation with avian sarcoma virus B77 in vitro

scientific article published in January 1982

Destruction of microfilament bundles in mouse embryo fibroblasts treated with inhibitors of energy metabolism

scientific article published on 01 June 1980

Dynamics and segregation of cell–matrix adhesions in cultured fibroblasts

article

Effects of H-7 on the iris and ciliary muscle in monkeys

scientific article published on August 1998

Evidence that intermediate filament reorganization is induced by ATP-dependent contraction of the actomyosin cortex in permeabilized fibroblasts ⬇️

scientific article published on March 1, 1991

Exploring the neighborhood: adhesion-coupled cell mechanosensors.

scientific article

Fibroblast polarization is a matrix-rigidity-dependent process controlled by focal adhesion mechanosensing.

scientific article

Focal adhesions as mechanosensors: a physical mechanism.

scientific article

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

scientific article published in June 2001

Focal contacts of normal and RSV-transformed quail cells. Hypothesis of the transformation-induced deficient maturation of focal contacts.

scientific article published on June 1985

Force-driven polymerization in cells: actin filaments and focal adhesions

scientific article published on 4 November 2005

Forces and constraints controlling podosome assembly and disassembly

scientific article published on 01 July 2019

How do microtubules guide migrating cells?

scientific article published on 01 December 2002

Integrin-matrix clusters form podosome-like adhesions in the absence of traction forces

scientific journal article

Interactions of normal and neoplastic cells with various surfaces.

scientific article published in May 1973

Intermediate filament collapse is an ATP-dependent and actin-dependent process

scientific article

Involvement of Rho GAP GRAF1 in maintenance of epithelial phenotype

scientific article published on 2 September 2016

Involvement of microtubules in the control of adhesion-dependent signal transduction.

scientific article published on October 1996

Involvement of the Rho–mDia1 pathway in the regulation of Golgi complex architecture and dynamics ⬇️

scientific article published on June 16, 2011

It depends on the hinge: a structure-functional analysis of galectin-8, a tandem-repeat type lectin

scientific article published on 24 February 2006

Kinectin-mediated endoplasmic reticulum dynamics supports focal adhesion growth in the cellular lamella ⬇️

scientific article published on October 27, 2010

Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways

scientific journal article

Latrunculin-A increases outflow facility in the monkey

scientific article published on 01 April 1999

Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption.

scientific article published on March 2003

Magic touch: how does cell-cell adhesion trigger actin assembly?

scientific article

Mammalian diaphanous-related formin Dia1 controls the organization of E-cadherin-mediated cell-cell junctions.

scientific article

Mechanical stimulation induces formin-dependent assembly of a perinuclear actin rim

scientific article published on 4 May 2015

Mechanisms of regulation of pseudopodial activity by the microtubule system

scientific article published on 01 January 1993

Mechanobiology

scientific article published on 7 April 2010

Mechanosensing Controlled Directly by Tyrosine Kinases.

scientific article

Microtubular system in cultured mouse epithelial cells

scientific article published on July 1, 1978

Microtubule dynamics: mechanism, regulation, and function.

scientific article published on January 1991

Microtubules in mouse embryo fibroblasts extracted with Triton X-100

scientific article published on 01 September 1978

Molecular interactions in the submembrane plaque of cell-cell and cell-matrix adhesions.

scientific article published on January 1995

Molecular mapping of tyrosine-phosphorylated proteins in focal adhesions using fluorescence resonance energy transfer

scientific article

Morphogenetic Effects of Neuregulin (Neu Differentiation Factor) in Cultured Epithelial Cells ⬇️

scientific article published on November 1, 1998

Multinucleation-induced improvement of the spreading of transformed cells on the substratum.

scientific article

Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion

scientific article published on 09 August 2019

Novel localization of formin mDia2: importin β-mediated delivery to and retention at the cytoplasmic side of the nuclear envelope

scientific article published on 30 October 2015

Ordering of myosin II filaments driven by mechanical forces: experiments and theory

scientific article published in May 2018

Physical Model for Self-Organization of Actin Cytoskeleton and Adhesion Complexes at the Cell Front ⬇️

scientific article published on April 18, 2012

Physical state of the extracellular matrix regulates the structure and molecular composition of cell-matrix adhesions

scientific article

Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO

scientific article published on 22 December 2016

Processive capping by formin suggests a force-driven mechanism of actin polymerization

scientific article published on 13 December 2004

Pseudopodial activity at the active edge of migrating fibroblast is decreased after drug-induced microtubule depolymerization

scientific article published on 01 January 1991

Publisher Correction: A mechano-signalling network linking microtubules, myosin IIA filaments and integrin-based adhesions

scientific article published on 01 July 2019

Role of ATP in the regulation of stability of cytoskeletal structures.

scientific article published on March 1983

Role of focal adhesions and mechanical stresses in the formation and progression of the lamellipodium-lamellum interface [corrected]

scientific article

Serum dependence of expression of the transformed phenotype: experiments with subline of mouse L fibroblasts adapted to growth in serum-free medium

scientific article published in July 1976

Signaling function of alpha-catenin in microtubule regulation

scientific article

Stimulation of actin synthesis in phalloidin-treated cells. Evidence for autoregulatory control

scientific article published on 01 December 1990

Structured illumination microscopy reveals focal adhesions are composed of linear subunits.

scientific article published on May 2015

The role of sphingolipids in the maintenance of fibroblast morphology. The inhibition of protrusional activity, cell spreading, and cytokinesis induced by fumonisin B1 can be reversed by ganglioside GM3.

scientific article published on January 1997

The state of actin assembly regulates actin and vinculin expression by a feedback loop

scientific article published on March 1995

Transmembrane crosstalk between the extracellular matrix--cytoskeleton crosstalk

scientific article (publication date: November 2001)

Transverse pattern of microfilament bundles induced in epitheliocytes by cylindrical substrata.

scientific article published on February 1995

Visualization of cellular focal contacts using a monoclonal antibody to 80 kD serum protein adsorbed on the substratum

scientific article published on 01 December 1983

YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth

scientific article published on 18 April 2014

p120 catenin affects cell motility via modulation of activity of Rho-family GTPases: a link between cell-cell contact formation and regulation of cell locomotion.

scientific article

List of works by Alexander Bershadsky

A mechano-signalling network linking microtubules, myosin IIA filaments and integrin-based adhesions

A new dimension in retrograde flow: centripetal movement of engulfed particles.

A novel mechanism of actin filament processive capping by formin: solution of the rotation paradox.

Actin cytoskeleton of spread fibroblasts appears to assemble at the cell edges

Actomyosin-generated tension controls the molecular kinetics of focal adhesions.

Adhesion-dependent cell mechanosensitivity.

Adhesion-mediated mechanosensitivity: a time to experiment, and a time to theorize.

Allicin inhibits cell polarization, migration and division via its direct effect on microtubules.

Analysis of the local organization and dynamics of cellular actin networks

Assembly and mechanosensory function of focal adhesions: experiments and models.

Association of intermediate filaments with vinculin-containing adhesion plaques of fibroblasts

Cadherin-mediated regulation of microtubule dynamics

Calculation of forces at focal adhesions from elastic substrate data: the effect of localized force and the need for regularization

Caldesmon transgene expression disrupts focal adhesions in HTM cells and increases outflow facility in organ-cultured human and monkey anterior segments.

Cellular chirality arising from the self-organization of the actin cytoskeleton.

Cellular contractility requires ubiquitin mediated proteolysis

Comparative dynamics of retrograde actin flow and focal adhesions: formation of nascent adhesions triggers transition from fast to slow flow

Cortactin releases the brakes in actin- based motility by enhancing WASP-VCA detachment from Arp2/3 branches.

Crawling cell locomotion revisited

Cytoskeleton of mouse embryo fibroblasts. Electron microscopy of platinum replicas

Cytoskeleton of rat neoplastic cells of spontaneous origin and their derivatives after supertransformation with avian sarcoma virus B77 in vitro

Destruction of microfilament bundles in mouse embryo fibroblasts treated with inhibitors of energy metabolism

Dynamics and segregation of cell–matrix adhesions in cultured fibroblasts

Effects of H-7 on the iris and ciliary muscle in monkeys

Evidence that intermediate filament reorganization is induced by ATP-dependent contraction of the actomyosin cortex in permeabilized fibroblasts ⬇️

Exploring the neighborhood: adhesion-coupled cell mechanosensors.

Fibroblast polarization is a matrix-rigidity-dependent process controlled by focal adhesion mechanosensing.

Focal adhesions as mechanosensors: a physical mechanism.

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

Focal contacts of normal and RSV-transformed quail cells. Hypothesis of the transformation-induced deficient maturation of focal contacts.

Force-driven polymerization in cells: actin filaments and focal adhesions

Forces and constraints controlling podosome assembly and disassembly

How do microtubules guide migrating cells?

Integrin-matrix clusters form podosome-like adhesions in the absence of traction forces

Interactions of normal and neoplastic cells with various surfaces.

Intermediate filament collapse is an ATP-dependent and actin-dependent process

Involvement of Rho GAP GRAF1 in maintenance of epithelial phenotype

Involvement of microtubules in the control of adhesion-dependent signal transduction.

Involvement of the Rho–mDia1 pathway in the regulation of Golgi complex architecture and dynamics ⬇️

It depends on the hinge: a structure-functional analysis of galectin-8, a tandem-repeat type lectin

Kinectin-mediated endoplasmic reticulum dynamics supports focal adhesion growth in the cellular lamella ⬇️

Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways

Latrunculin-A increases outflow facility in the monkey

Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption.

Magic touch: how does cell-cell adhesion trigger actin assembly?

Mammalian diaphanous-related formin Dia1 controls the organization of E-cadherin-mediated cell-cell junctions.

Mechanical stimulation induces formin-dependent assembly of a perinuclear actin rim

Mechanisms of regulation of pseudopodial activity by the microtubule system

Mechanobiology

Mechanosensing Controlled Directly by Tyrosine Kinases.

Microtubular system in cultured mouse epithelial cells

Microtubule dynamics: mechanism, regulation, and function.

Microtubules in mouse embryo fibroblasts extracted with Triton X-100

Molecular interactions in the submembrane plaque of cell-cell and cell-matrix adhesions.

Molecular mapping of tyrosine-phosphorylated proteins in focal adhesions using fluorescence resonance energy transfer

Morphogenetic Effects of Neuregulin (Neu Differentiation Factor) in Cultured Epithelial Cells ⬇️

Multinucleation-induced improvement of the spreading of transformed cells on the substratum.

Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion

Novel localization of formin mDia2: importin β-mediated delivery to and retention at the cytoplasmic side of the nuclear envelope

Ordering of myosin II filaments driven by mechanical forces: experiments and theory

Physical Model for Self-Organization of Actin Cytoskeleton and Adhesion Complexes at the Cell Front ⬇️

Physical state of the extracellular matrix regulates the structure and molecular composition of cell-matrix adhesions

Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO

Processive capping by formin suggests a force-driven mechanism of actin polymerization

Pseudopodial activity at the active edge of migrating fibroblast is decreased after drug-induced microtubule depolymerization

Publisher Correction: A mechano-signalling network linking microtubules, myosin IIA filaments and integrin-based adhesions

Role of ATP in the regulation of stability of cytoskeletal structures.

Role of focal adhesions and mechanical stresses in the formation and progression of the lamellipodium-lamellum interface [corrected]

Serum dependence of expression of the transformed phenotype: experiments with subline of mouse L fibroblasts adapted to growth in serum-free medium

Signaling function of alpha-catenin in microtubule regulation

Stimulation of actin synthesis in phalloidin-treated cells. Evidence for autoregulatory control

Structured illumination microscopy reveals focal adhesions are composed of linear subunits.

The role of sphingolipids in the maintenance of fibroblast morphology. The inhibition of protrusional activity, cell spreading, and cytokinesis induced by fumonisin B1 can be reversed by ganglioside GM3.

The state of actin assembly regulates actin and vinculin expression by a feedback loop

Transmembrane crosstalk between the extracellular matrix--cytoskeleton crosstalk

Transverse pattern of microfilament bundles induced in epitheliocytes by cylindrical substrata.

Visualization of cellular focal contacts using a monoclonal antibody to 80 kD serum protein adsorbed on the substratum

YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth

p120 catenin affects cell motility via modulation of activity of Rho-family GTPases: a link between cell-cell contact formation and regulation of cell locomotion.