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List of works by Jesper L. Kristensen

(11)C-labeling and preliminary evaluation of pimavanserin as a 5-HT2A receptor PET-radioligand

scientific article published on 20 January 2015

(11)C-labeling and preliminary evaluation of vortioxetine as a PET radioligand

scientific article

18F-Labelling of electron rich iodonium ylides: application to the radiosynthesis of potential 5-HT2A receptor PET ligands.

scientific article published on 5 May 2017

5-HT2A/5-HT2C Receptor Pharmacology and Intrinsic Clearance of N-Benzylphenethylamines Modified at the Primary Site of Metabolism.

scientific article published on September 2016

A Prodrug Approach Involving In Situ Depot Formation to Achieve Localized and Sustained Action of Diclofenac After Joint Injection

scientific article published on 29 October 2014

A strategic approach to [6,6]-bicyclic lactones: application towards the CD fragment of DHβE

scientific article

Accelerating preclinical PET-screening: reductive amination with [11C]methoxybenzaldehydes

scholarly article in RSC Advances, vol. 4 no. 41, 2014

Aminolysis of Resin-BoundN-Nosylaziridine-2-carboxylic Acids

scientific article published in July 2006

Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH.

scientific article published on 12 July 2016

Computational Methods to Predict the Regioselectivity of Electrophilic Aromatic Substitution Reactions of Heteroaromatic Systems

Conformationally Constrained Peptidomimetics as Inhibitors of the Protein Arginine Methyl Transferases.

scientific article

Convenient Entry to F-Labeled Amines through the Staudinger Reduction

scientific article published on 22 January 2019

Convergent 18F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT2A receptor PET ligands

scientific article published on 29 August 2016

Convergent synthesis of 3-arylated 1-hydroxypyrazoles via 3-metalated pyrazole-1-oxides

scientific article published on 01 December 2001

Convergent synthesis of 6-substituted phenanthridines via anionic ring closure

scientific article published on 01 January 2002

Correlating the metabolic stability of psychedelic 5-HT₂A agonists with anecdotal reports of human oral bioavailability

scientific article published on 12 February 2014

Cover Feature: Convenient Entry to 18 F-Labeled Amines through the Staudinger Reduction (Eur. J. Org. Chem. 8/2019)

Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHβE Suggests a Unique Mode of Antagonism

scientific article

DARK Classics in Chemical Neuroscience: NBOMes

scientific article published on 12 November 2019

Design, synthesis and in vitro pharmacology of GluK1 and GluK3 antagonists. Studies towards the design of subtype-selective antagonists through 2-carboxyethyl-phenylalanines with substituents interacting with non-conserved residues in the GluK bindin

scientific article published in October 2014

Design, synthesis, and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists.

scientific article

Detailed Characterization of the In Vitro Pharmacological and Pharmacokinetic Properties of N-(2-Hydroxybenzyl)-2,5-Dimethoxy-4-Cyanophenylethylamine (25CN-NBOH), a Highly Selective and Brain-Penetrant 5-HT2A Receptor Agonist

scientific article published on 30 March 2017

Development of a (11)C-labeled tetrazine for rapid tetrazine-trans-cyclooctene ligation

scientific article published on 27 March 2013

Development of a simple proton nuclear magnetic resonance-based procedure to estimate the approximate distribution coefficient at physiological pH (logD7.4): Evaluation and comparison to existing practices

scientific article published on 18 November 2016

Direct Cu-mediated aromatic <sup>18</sup>F-labeling of highly reactive tetrazines for pretargeted bioorthogonal PET imaging

scientific article published in 2021

Dissecting the binding mode of low affinity phage display peptide ligands to protein targets by hydrogen/deuterium exchange coupled to mass spectrometry

scientific article published on 11 November 2014

Dual Nicotinic Acetylcholine Receptors α4β2 Antagonists/α7 Agonists: Synthesis, Docking Studies and Pharmacological Evaluation of Tetrahydroisoquinolines and Tetrahydroisoquinolinium Salts.

scientific article published on 31 January 2018

Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine

scientific article published on 28 May 2019

Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases

article published in 2011

Evaluation of 3-Ethyl-3-(phenylpiperazinylbutyl)oxindoles as PET Ligands for the Serotonin 5-HT₇ Receptor: Synthesis, Pharmacology, Radiolabeling, and in Vivo Brain Imaging in Pigs

scientific article published on 13 April 2015

Exploring the neuroleptic substituent in octoclothepin: potential ligands for positron emission tomography with subnanomolar affinity for α(1)-adrenoceptors.

scientific article

Hallucinogen-like effects of 2-([2-(4-cyano-2,5-dimethoxyphenyl) ethylamino]methyl)phenol (25CN-NBOH), a novel N-benzylphenethylamine with 100-fold selectivity for 5-HT₂A receptors, in mice

scientific article

Human biodistribution and radiation dosimetry of the 5-HT2A receptor agonist Cimbi-36 labeled with carbon-11 in two positions

scientific article published on 31 July 2019

Identification of a new metabolite of GHB: gamma-hydroxybutyric acid glucuronide

scientific article published on 23 April 2013

Improved radiosynthesis and preliminary in vivo evaluation of the 11C-labeled tetrazine [11C]AE-1 for pretargeted PET imaging

scientific article published on 13 February 2019

In situ generation of the Ohira-Bestmann reagent from stable sulfonyl azide: scalable synthesis of alkynes from aldehydes

scientific article published on 25 September 2014

In vivo effects of 3,4-methylenedioxymethamphetamine (MDMA) and its deuterated form in rodents: Drug discrimination and thermoregulation

scientific article published on 13 January 2020

Inhibitor scaffold for the histone lysine demethylase KDM4C (JMJD2C).

scientific article

Inhibitors of histone demethylases

scientific article published on February 2011

Labeling and preliminary in vivo evaluation of the 5-HT(7) receptor selective agonist [(11)C]E-55888.

scientific article published on 21 March 2015

Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted <i>In Vivo</i> Chemistry

scientific article published in 2021

Locomotor effects of 3,4-methylenedioxymethamphetamine (MDMA) and its deuterated form in mice: psychostimulant effects, stereotypy, and sensitization

scientific article published on 15 November 2019

Long-Acting Diclofenac Ester Prodrugs for Joint Injection: Kinetics, Mechanism of Degradation, and In Vitro Release From Prodrug Suspension

scientific article published on 27 July 2016

Metabolic Fate of Hallucinogenic NBOMes

scientific article published on 15 December 2015

Novel 4-(piperidin-4-yl)-1-hydroxypyrazoles as gamma-aminobutyric acid(A) receptor ligands: synthesis, pharmacology, and structure-activity relationships.

scientific article published on April 2010

Palladium-catalyzed asymmetric allylic alkylation of alpha-aryl ketones

scientific article published in September 2002

Preclinical safety assessment of the 5-HT2A receptor agonist PET radioligand [ 11C]Cimbi-36.

scientific article

Radiolabelling and PET brain imaging of the α₁-adrenoceptor antagonist Lu AE43936.

scientific article published on 17 November 2012

Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT (2A) agonist PET tracers

scientific article

Radiosynthesis and in vivo evaluation of novel radioligands for PET imaging of cerebral 5-HT7 receptors.

scientific article published on 24 February 2014

Ring opening of pymisyl-protected aziridines with organocuprates

scientific article published on November 2010

Structure-activity relationships of constrained phenylethylamine ligands for the serotonin 5-HT2 receptors

scientific article (publication date: 2013)

Substrate- and cofactor-independent inhibition of histone demethylase KDM4C.

scientific article

Synthesis and Biological Evaluation of 4-(Aminomethyl)-1-hydroxypyrazole Analogues of Muscimol as γ-Aminobutyric AcidA Receptor Agonists

scientific article published on 23 January 2013

Synthesis and Characterisation of Substrate-Based Peptides as Inhibitors of Histone Demethylase KDM4C.

scientific article published on 13 June 2016

Synthesis and Pharmacological Evaluation of DHβE Analogues as Neuronal Nicotinic Acetylcholine Receptor Antagonists.

scientific article published on 20 May 2014

Synthesis and SAR study of a novel series of dopamine receptor agonists

scientific article published on 15 November 2013

Synthesis and application of a new fluorous-tagged ammonia equivalent.

scientific article published on 23 March 2010

Synthesis and binding studies of 2-arylapomorphines

scientific article published on 13 October 2005

Synthesis and evaluation of (18)F-labeled 5-HT2A receptor agonists as PET ligands

scientific article published on 19 April 2016

Synthesis and evaluation of [¹¹C]Cimbi-806 as a potential PET ligand for 5-HT₇ receptor imaging

scientific article published on 18 May 2012

Synthesis and in vitro evaluation of oxindole derivatives as potential radioligands for 5-HT(7) receptor imaging with PET.

scientific article published on 31 August 2012

Synthesis and pharmacological evaluation of N-benzyl substituted 4-bromo-2,5-dimethoxyphenethylamines as 5-HT2A/2C partial agonists

scientific article published on 17 December 2014

Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists.

scientific article

Synthesis of enantiopure 3-substituted morpholines

scientific article published on November 2010

Synthesis of ortho substituted arylboronic esters by in situ trapping of unstable lithio intermediates

scientific article published on 01 May 2001

Synthesis of pentacyclic 13-azadibenzo[a,de]anthracenes via anionic cascade ring closure

scientific article published in May 2003

Synthesis of substituted 2-cyanoarylboronic esters

scientific article published in March 2006

Synthesis of tertiary benzamides via Pd-catalyzed coupling of arylboronic esters and carbamoyl chlorides

scientific article published in June 2005

Synthesis, radiofluorination, and preliminary evaluation of the potential 5-HT2A receptor agonists [18 F]Cimbi-92 and [18 F]Cimbi-150.

scientific article published on 30 August 2017

Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

scientific article published on 25 August 2011

The 5-hydroxytryptamine 2A receptor agonists DOI and 25CN-NBOH decrease marble burying and reverse 8-OH-DPAT-induced deficit in spontaneous alternation

scientific article published on 03 November 2019

The importance of small polar radiometabolites in molecular neuroimaging: A PET study with [11C]Cimbi-36 labeled in two positions

scientific article published in January 2017

Total synthesis of ascididemin via anionic cascade ring closure

scientific article published on 03 August 2012

Trans-Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging

scientific article published on 02 January 2020

Tweaking agonist efficacy at N-methyl-D-aspartate receptors by site-directed mutagenesis.

scientific article published on 30 August 2005

Tying up Nicotine: New Selective Competitive Antagonist of the Neuronal Nicotinic Acetylcholine Receptors.

scientific article published on 4 March 2015

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