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List of works by Claudio U Köser

'Those who cannot remember the past are condemned to repeat it': Drug-susceptibility testing for bedaquiline and delamanid

scientific article published on 25 February 2019

A pilot study of rapid whole-genome sequencing for the investigation of a Legionella outbreak

scientific article (publication date: 9 January 2013)

A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis

scientific article published on 28 December 2017

Comment on: characterization of the embB gene in Mycobacterium tuberculosis isolates from Barcelona and rapid detection of main mutations related to ethambutol resistance using a low-density DNA array

scientific article published on 20 April 2014

Consequences of whiB7 ( Rv3197A ) Mutations in Beijing Genotype Isolates of the Mycobacterium tuberculosis Complex ⬇️

scientific article published on July 1, 2013

Convergent evolution and topologically disruptive polymorphisms among multidrug-resistant tuberculosis in Peru.

scientific article

Drug-resistance mechanisms and tuberculosis drugs

scientific article

Emergent and evolving antimicrobial resistance cassettes in community-associated fusidic acid and meticillin-resistant Staphylococcus aureus.

scientific article published on 19 February 2015

Genetic diversity within Mycobacterium tuberculosis complex impacts on the accuracy of genotypic pyrazinamide drug-susceptibility assay

scientific article

Genome sequencing defines phylogeny and spread of methicillin-resistant Staphylococcus aureus in a high transmission setting

scientific article published on 9 December 2014

Genomic diversity among drug sensitive and multidrug resistant isolates of Mycobacterium tuberculosis with identical DNA fingerprints

scientific article

Genomic identification of cryptic susceptibility to penicillins and β-lactamase inhibitors in methicillin-resistant Staphylococcus aureus

scientific article published on 24 June 2019

Impact of Fgd1 and ddn diversity in Mycobacterium tuberculosis complex on in vitro susceptibility to PA-824.

scientific article published on 19 September 2011

Importance of the Genetic Diversity within the Mycobacterium tuberculosis Complex for the Development of Novel Antibiotics and Diagnostic Tests of Drug Resistance ⬇️

scientific article published on September 24, 2012

Isoniazid Resistance in Mycobacterium tuberculosis Is a Heterogeneous Phenotype Composed of Overlapping MIC Distributions with Different Underlying Resistance Mechanisms

scientific article published on 24 June 2019

Limited evidence for need for region-specific, genotypic drug-susceptibility assays for Mycobacterium tuberculosis

scientific article published on 22 November 2017

MDR M. tuberculosis outbreak clone in Eswatini missed by Xpert has elevated bedaquiline resistance dated to the pre-treatment era

scientific article published on 25 November 2020

Mycobacterium canettii is intrinsically resistant to both pyrazinamide and pyrazinoic acid

scientific article

Mycobacterium tuberculosis drug-resistance testing: challenges, recent developments and perspectives.

scientific article published on 31 October 2016

Mycobacterium tuberculosis resistance prediction and lineage classification from genome sequencing: comparison of automated analysis tools

scientific article published on 20 April 2017

New methods for identifying infectious diseases.

scientific article

Overview of errors in the reference sequence and annotation of Mycobacterium tuberculosis H37Rv, and variation amongst its isolates ⬇️

scientific article published on June 23, 2011

Phylogenetic polymorphisms in antibiotic resistance genes of the Mycobacterium tuberculosis complex

scientific article published on 23 January 2014

Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex

scientific article published on 06 March 2020

Prevalence and genetic profiles of isoniazid resistance in tuberculosis patients: A multicountry analysis of cross-sectional data

scientific article published on 21 January 2020

Rapid bacterial whole-genome sequencing to enhance diagnostic and public health microbiology

scientific article

Rapid single-colony whole-genome sequencing of bacterial pathogens

scientific article

Rapid whole-genome sequencing for investigation of a neonatal MRSA outbreak

scientific article published on June 2012

Rapid whole-genome sequencing for investigation of a suspected tuberculosis outbreak

scientific article published on 21 November 2012

Read length and repeat resolution: exploring prokaryote genomes using next-generation sequencing technologies

scientific article

Reply to Dookie et al., "Whole-Genome Sequencing To Guide the Selection of Treatment for Drug-Resistant Tuberculosis"

scientific article published on 27 July 2018

Revised Interpretation of the Hain Lifescience GenoType MTBC To Differentiate Mycobacterium canettii and Members of the Mycobacterium tuberculosis Complex

scientific article published on 24 May 2019

Role of Epistasis in Amikacin, Kanamycin, Bedaquiline, and Clofazimine Resistance in Mycobacterium tuberculosis Complex

scientific article published on 30 August 2021

Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance

scientific article published on 2 October 2017

Role of mutations in dihydrofolate reductase DfrA (Rv2763c) and thymidylate synthase ThyA (Rv2764c) in Mycobacterium tuberculosis drug resistance

scientific article published on October 2010

Role of the Dihydrofolate Reductase DfrA (Rv2763c) in Trimethoprim-Sulfamethoxazole (Co-Trimoxazole) Resistance in Mycobacterium tuberculosis ⬇️

scientific article published on November 1, 2010

Routine use of microbial whole genome sequencing in diagnostic and public health microbiology

scientific article (publication date: 2012)

Single-nucleotide polymorphisms in Rv2629 are specific for Mycobacterium tuberculosis genotypes Beijing and Ghana but not associated with rifampin resistance

scientific article

Some Synonymous and Nonsynonymous gyrA Mutations in Mycobacterium tuberculosis Lead to Systematic False-Positive Fluoroquinolone Resistance Results with the Hain GenoType MTBDRsl Assays

scientific article published on 30 January 2017

Standards for MIC testing that apply to the majority of bacterial pathogens should also be enforced for Mycobacterium tuberculosis complex

scientific article published on 14 February 2019

Systematic review of mutations associated with resistance to the new and repurposed Mycobacterium tuberculosis drugs bedaquiline, clofazimine, linezolid, delamanid and pretomanid

scientific article published on 03 May 2020

Systematic rifampicin resistance errors with Xpert<sup>®</sup> MTB/RIF Ultra: implications for regulation of genotypic assays

scientific article published on 01 December 2020

The role of whole genome sequencing in antimicrobial susceptibility testing of bacteria: report from the EUCAST Subcommittee.

scientific article

The validity of Mycobacterium tuberculosis complex species identification. Comments on the article: "Differentiation of species within the Mycobacterium tuberculosis complex by molecular techniques"

scientific article published on 19 February 2011

Thr202Ala in thyA is a marker for the Latin American Mediterranean lineage of the Mycobacterium tuberculosis complex rather than para-aminosalicylic acid resistance.

scientific article

Thr270Ile in embC (Rv3793) is not a marker for ethambutol resistance in the Mycobacterium tuberculosis complex

scientific article published on April 2011

What Is Resistance? Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis.

scientific article

Whole-genome sequencing for rapid susceptibility testing of M. tuberculosis

scientific article published on July 2013

Whole-genome sequencing of multidrug-resistant Mycobacterium tuberculosis isolates from Myanmar

scientific article published on 30 May 2016

Wild-Type and Non-Wild-Type Mycobacterium tuberculosis MIC Distributions for the Novel Fluoroquinolone Antofloxacin Compared with Those for Ofloxacin, Levofloxacin, and Moxifloxacin

scientific article published on 20 June 2016

World Tuberculosis Day March 24th 2019 Theme: "It's TIME" - International Journal of Infectious Diseases Tuberculosis Theme Series

scientific article published on 23 February 2019

d-Cycloserine Pharmacokinetics/Pharmacodynamics, Susceptibility, and Dosing Implications in Multidrug-resistant Tuberculosis: A Faustian Deal

scientific article published on 01 November 2018

dfrA thyA Double Deletion in para-Aminosalicylic Acid-Resistant Mycobacterium tuberculosis Beijing Strains

scientific article published on 28 March 2016

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