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List of works by Monica Borgatti

A Novel Frameshift Mutation (+A) at Codon 18 of the β-Globin Gene Associated with High Persistence of Fetal Hemoglobin Phenotype and δβ-Thalassemia

article

A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3'UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) mRNA Enhances CFTR Expression in Calu-3 Cells

scientific article published on 05 April 2020

A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs

scientific article published on 23 June 2022

A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction

scientific article published on 31 March 2012

Accumulation of gamma-globin mRNA in human erythroid cells treated with angelicin

scientific article published in September 2003

Alternate PNA-DNA chimeras (PNA-DNA)(n): synthesis, binding properties and biological activity.

scientific article published on January 2007

Anti-inflammatory effect of miglustat in bronchial epithelial cells.

scientific article published on 23 September 2008

Antibacterial and anti-inflammatory activity of a temporin B peptide analogue on an in vitro model of cystic fibrosis

scientific article published on 6 August 2014

Antioxidant and antiproliferative activity of Laurus nobilis L. (Lauraceae) leaves and seeds essential oils against K562 human chronic myelogenous leukaemia cells

scientific article

Antiproliferative activity of Pt(II) and Pd(II) phosphine complexes with thymine and thymidine.

scientific article published in October 2006

Apoptosis of human primary osteoclasts treated with molecules targeting nuclear factor-kappaB.

scientific article

Aromatic polyamidines inhibiting the Tat-induced HIV-1 transcription recognize structured TAR-RNA.

scientific article

Bergamot (Citrus bergamia Risso) fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines.

scientific article

Bergamot (Citrus bergamia Risso) fruit extracts as γ-globin gene expression inducers: phytochemical and functional perspectives.

scientific article published on 16 April 2009

Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA.

scientific article published in February 2004

Biosensor Technology and Surface Plasmon Resonance for Real-Time Detection of Genetically Modified Roundup Ready Soybean Gene Sequences

article

C(5) modified uracil derivatives showing antiproliferative and erythroid differentiation inducing activities on human chronic myelogenous leukemia K562 cells.

scientific article published on 21 September 2011

Cationic liposomes as delivery systems for double-stranded PNA-DNA chimeras exhibiting decoy activity against NF-kappaB transcription factors

scientific article

Complexation to Cationic Microspheres of Double-Stranded Peptide Nucleic Acid-DNA Chimeras Exhibiting Decoy Activity

Corilagin is a potent inhibitor of NF-kappaB activity and downregulates TNF-alpha induced expression of IL-8 gene in cystic fibrosis IB3-1 cells

scientific article published on 4 May 2012

Design, synthesis, and biological evaluation of hybrid molecules containing alpha-methylene-gamma-butyrolactones and alpha-bromoacryloyl moieties.

scientific article published on December 2005

Detection of the sickle hemoglobin allele using a surface plasmon resonance based biosensor

scientific article published on 01 October 2019

Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations

scientific article published on 9 July 2009

Development of a novel furocoumarin derivative inhibiting NF-κB dependent biological functions: design, synthesis and biological effects

scientific article published on July 23, 2011

Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells

scientific article published on 27 September 2017

Differentiation and apoptosis in UVA-irradiated cells treated with furocoumarin derivatives.

scientific article published on August 2009

Direct detection of point mutations in nonamplified human genomic DNA.

scientific article

Discovery of Novel Fetal Hemoglobin Inducers through Small Chemical Library Screening

scientific article published on 08 October 2020

Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression

scientific article

Effect of atrial natriuretic peptide on reactive oxygen species-induced by hydrogen peroxide in THP-1 monocytes: role in cell growth, migration and cytokine release

scientific article published on 11 October 2013

Effects of biomaterials for Lab-on-a-chip production on cell growth and expression of differentiated functions of leukemic cell lines.

scientific article published on 13 July 2010

Effects of rapamycin on accumulation of alpha-, beta- and gamma-globin mRNAs in erythroid precursor cells from beta-thalassaemia patients

scientific article

Erythroid differentiation ability of butyric acid analogues: identification of basal chemical structures of new inducers of foetal haemoglobin

scientific article

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions

scientific article published on 03 December 2014

Erythroid induction of chronic myelogenous leukemia K562 cells following treatment with a photoproduct derived from the UV-A irradiation of 5-methoxypsoralen.

scientific article published on September 2010

Everolimus is a potent inducer of erythroid differentiation and gamma-globin gene expression in human erythroid cells

scientific article

Expression of microRNA-93 and Interleukin-8 during Pseudomonas aeruginosa-mediated induction of proinflammatory responses.

scientific article published on June 2014

Expression of pro-inflammatory interleukin-8 is reduced by ayurvedic decoctions.

scientific article published on 6 January 2014

Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of {beta}-Thalassemia and Sickle-Cell Anemia.

scientific article published on 11 December 2007

Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation.

scientific article published on 4 May 2015

In vitro antiproliferative effects on human tumor cell lines of extracts from the Bangladeshi medicinal plant Aegle marmelos Correa

scientific article

Increase in gamma-globin mRNA content in human erythroid cells treated with angelicin analogs

scientific article published on 25 September 2009

Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells

scientific article

Induction by TNF-α of IL-6 and IL-8 in cystic fibrosis bronchial IB3-1 epithelial cells encapsulated in alginate microbeads

scientific article published on 8 September 2010

Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis

scientific article

Induction of apoptosis of osteoclasts by targeting transcription factors with decoy molecules.

scientific article published on December 2006

Induction of gamma-globin mRNA, erythroid differentiation and apoptosis in UVA-irradiated human erythroid cells in the presence of furocumarin derivatives.

scientific article published on 13 October 2007

Inhibitory Effects of Bangladeshi Medicinal Plant Extracts on Interactions between Transcription Factors and Target DNA Sequences

scientific article published on September 2008

Interaction of the human NF-kappaB p52 transcription factor with DNA-PNA hybrids mimicking the NF-kappaB binding sites of the human immunodeficiency virus type 1 promoter.

scientific article

Involvement of miRNA in erythroid differentiation

scientific article published on February 2012

In vitro evaluation of the anti-proliferative activities of the wood essential oils of three Cedrus species against K562 human chronic myelogenous leukaemia cells

scientific article

Levitation and movement of human tumor cells using a printed circuit board device based on software-controlled dielectrophoresis

scientific article published in May 2003

Levitation and movement of tripalmitin‐based cationic lipospheres on a dielectrophoresis‐based lab‐on‐a‐chip device

Lysis-on-chip of single target cells following forced interaction with CTLs or NK cells on a dielectrophoresis-based array

scientific article published on 4 September 2013

MPB-07 Reduces the Inflammatory Response toPseudomonas aeruginosain Cystic Fibrosis Bronchial Cells

scientific article published on 29 December 2006

Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells.

scientific article

Modulation of iNOS expression by a nitric oxide-releasing derivative of the natural antioxidant ferulic acid in activated RAW 264.7 macrophages.

scientific article published on 27 January 2006

Modulation of the Expression of the Proinflammatory IL-8 Gene in Cystic Fibrosis Cells by Extracts Deriving from Olive Mill Waste Water

scientific article published on July 7, 2013

Modulation of the biological activity of microRNA-210 with peptide nucleic acids (PNAs).

scientific article

Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites

scientific article published on December 2001

NF-kappaB activation is required for apoptosis in fibrocystin/polyductin-depleted kidney epithelial cells

scientific article

New uracil dimers showing erythroid differentiation inducing activities.

scientific article

Non-invasive Prenatal Testing Using Fetal DNA

scientific article published on 01 April 2019

Non-invasive fetal sex diagnosis in plasma of early weeks pregnants using droplet digital PCR.

scientific article

Peptide nucleic acids targeting miR-221 modulate p27Kip1 expression in breast cancer MDA-MB-231 cells

scientific article

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells

scientific article

Postnatal and non-invasive prenatal detection of β-thalassemia mutations based on Taqman genotyping assays

scientific article

Preparation and evaluation of the in vitro erythroid differentiation induction properties of some esters of methyl 3,4-O-isopropylidene-beta-D-galactopyranoside and 2,3-O-isopropylidene-D-mannofuranose.

scientific article published in February 2002

Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients

scientific article published on November 2009

Programmable interactions of functionalized single bioparticles in a dielectrophoresis-based microarray chip

scientific article published on 22 August 2013

Psoralen derivatives as inhibitors of NF-κB/DNA interaction: synthesis, molecular modeling, 3D-QSAR, and biological evaluation

scientific article published on 25 February 2013

Pyrogallol, an active compound from the medicinal plant Emblica officinalis, regulates expression of pro-inflammatory genes in bronchial epithelial cells

scientific article published on 27 August 2008

Rapamycin-mediated induction of gamma-globin mRNA accumulation in human erythroid cells.

scientific article published on August 2004

Release of sICAM-1 in oocytes and in vitro fertilized human embryos

scientific article

Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients

scientific article

Screening Readthrough Compounds to Suppress Nonsense Mutations: Possible Application to β-Thalassemia

scientific article published on 21 January 2020

Structural characterization of promoter sequences of the gene coding human PKI55 protein, a protein kinase C inhibitor

scientific article published on 7 December 2008

Surface plasmon resonance analysis to detect the β+IVSI-110 thalassemia mutation in circulating cell-free fetal DNA.

scientific article

Synthesis and biological activity of alpha-bromoacryloyl lexitropsin conjugates.

scientific article published on 11 July 2005

Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents

scientific article published on June 2006

Targeting microRNAs involved in human diseases: a novel approach for modification of gene expression and drug development

scientific article published on 16 August 2011

The loss of cellular junctions in epithelial lung cells induced by cigarette smoke is attenuated by corilagin

scientific article

Tobramycin is a suppressor of premature termination codons

scientific article

Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites

scientific article

Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function.

scientific article published on 10 December 2010

UPF1 silenced cellular model systems for screening of read-through agents active on β039 thalassemia point mutation.

scientific article published on 15 May 2018

Uptake by human glioma cell lines and biological effects of a peptide-nucleic acids targeting miR-221.

scientific article published on 5 March 2014

Virtual screening against nuclear factor κB (NF-κB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-κB dependent biological functions involved in cystic fibrosis.

scientific article

Virtual screening against p50 NF-kappaB transcription factor for the identification of inhibitors of the NF-kappaB-DNA interaction and expression of NF-kappaB upregulated genes.

scientific article published in December 2009

Y-chromosome identification in circulating cell-free fetal DNA using surface plasmon resonance

scientific article

gamma-Hydroxymethyl PNAs: Synthesis, interaction with DNA and inhibition of protein/DNA interactions

scientific article

mTOR and STAT3 Pathway Hyper-Activation is Associated with evated Interleukin-6 Levels in Patients with Shwachman-Diamond Syndrome: Further Evidence of Lymphoid Lineage Impairment

scientific article published on 05 March 2020

miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs

scientific article published on December 2011

trans-Resveratrol in Nutraceuticals: Issues in Retail Quality and Effectiveness