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List of works by Loretta Lazzarato

(Nitrooxyacyloxy)methyl esters of aspirin as novel nitric oxide releasing aspirins

scientific article published in August 2009

A Nonmetal-Containing Nitric Oxide Donor Activated with Single-Photon Green Light.

scientific article

A Potent and Selective P-gp Modulator for Altering Multidrug Resistance Due to Pump Overexpression.

scientific article published on 21 January 2016

A molecular hybrid producing simultaneously singlet oxygen and nitric oxide by single photon excitation with green light

scientific article published on 20 December 2018

A new class of ibuprofen derivatives with reduced gastrotoxicity

scientific article

A nitric oxide-donor furoxan moiety improves the efficacy of edaravone against early renal dysfunction and injury evoked by ischemia/reperfusion

scientific article

A novel hybrid aspirin-NO-releasing compound inhibits TNFalpha release from LPS-activated human monocytes and macrophages

scientific article published on 31 July 2008

A rapid screening for cytochrome P450 catalysis on new chemical entities: cytochrome P450 BM3 and 1,2,5-oxadiazole derivatives

scientific article published on 13 September 2012

Aceclofenac–Galactose Conjugate: Design, Synthesis, Characterization, and Pharmacological and Toxicological Evaluations

scientific article published on 27 June 2018

Amphiphilic NO-Donor Antioxidants

scientific article published on 01 February 2007

Antiinflammatory, gastrosparing, and antiplatelet properties of new NO-donor esters of aspirin

scientific article (publication date: 27 February 2003)

Can We Exploit β-Lactamases Intrinsic Dynamics for Designing More Effective Inhibitors?

scientific article published on 21 November 2020

Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells.

scientific article

Combination of PDT and NOPDT with a Tailored BODIPY Derivative

scientific article published on 07 November 2019

Corrigendum: Designing Multitarget Anti-inflammatory Agents: Chemical Modulation of the Lumiracoxib Structure toward Dual Thromboxane Antagonists-COX-2 Inhibitors

scholarly article by Massimo Bertinaria et al published 26 November 2012 in ChemMedChem

Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction

scientific article published on 31 March 2022

Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P-Glycoprotein Ligand Overcoming Multidrug Resistance in Cancer Stem Cells

scientific article published on 09 January 2019

Design, Synthesis and Characterization of N-oxide-containing Heterocycles with In vivo Sterilizing Antitubercular Activity.

scientific article published on 2 October 2017

Designing multitarget anti-inflammatory agents: chemical modulation of the lumiracoxib structure toward dual thromboxane antagonists-COX-2 inhibitors

scientific article

Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants.

scientific article published in December 2004

Doxorubicin-antioxidant co-drugs

scientific article published on 8 August 2013

Furazan and furoxan sulfonamides are strong α-carbonic anhydrase inhibitors and potential antiglaucoma agents

scientific article published on 17 June 2014

Furoxan Nitric Oxide Donors Disperse Pseudomonas aeruginosa Biofilms, Accelerate Growth, and Repress Pyoverdine Production

scientific article published on 19 June 2017

Galactosylated Pro-Drug of Ursodeoxycholic Acid: Design, Synthesis, Characterization, and Pharmacological Effects in a Rat Model of Estrogen-Induced Cholestasis.

scientific article published on 15 November 2017

H2S-Donating Doxorubicins May Overcome Cardiotoxicity and Multidrug Resistance

scientific article published on 27 April 2016

Light-Tunable Generation of Singlet Oxygen and Nitric Oxide with a Bichromophoric Molecular Hybrid: a Bimodal Approach to Killing Cancer Cells.

scientific article published on 5 November 2015

Mechanistic insights into cyclooxygenase irreversible inactivation by aspirin.

scientific article

Methotrexate-Loaded Solid Lipid Nanoparticles: Protein Functionalization to Improve Brain Biodistribution

scientific article published on 02 February 2019

Michael addition of Grignard reagents to tetraethyl ethenylidenebisphosphonate

article

Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance

scientific article published on 7 December 2012

Multitarget drugs: Focus on the NO-donor hybrid drugs

NO release regulated by doxorubicin as the green light-harvesting antenna

scientific article published on 21 May 2020

NO-Donor COX-2 Inhibitors. New Nitrooxy-Substituted 1,5-Diarylimidazoles Endowed with COX-2 Inhibitory and Vasodilator Properties

scientific article published on 03 March 2007

NO-Donor Phenols: A New Class of Products Endowed with Antioxidant and Vasodilator Properties

scientific article published on 01 May 2006

NO-donor melatonin derivatives: synthesis and in vitro pharmacological characterization

scientific article published on 01 April 2007

New Nitric Oxide or Hydrogen Sulfide Releasing Aspirins

scientific article published on 06 July 2011

New furoxan derivatives for the treatment of ocular hypertension

scientific article published on 18 December 2016

Nitric oxide donor doxorubicins accumulate into Doxorubicin-resistant human colon cancer cells inducing cytotoxicity

scientific article published on 4 April 2011

Nitrooxyacyl derivatives of salicylic acid: aspirin-like molecules that covalently inactivate cyclooxygenase-1.

scientific article published on 5 January 2011

Nitrooxymethyl-substituted analogues of celecoxib: synthesis and pharmacological characterization

scientific article published in March 2009

Novel antioxidant agents deriving from molecular combination of Vitamin C and NO-donor moieties

scientific article

Paracetamol-Galactose Conjugate: A Novel Prodrug for an Old Analgesic Drug

scientific article published on 12 September 2019

Physicochemical profile and in vitro permeation behavior of a new class of non-steroidal anti-inflammatory drug candidates

scientific article published on 25 March 2010

Searching for new NO-donor aspirin-like molecules: Furoxanylacyl derivatives of salicylic acid and related furazans

scientific article published on 16 August 2011

Searching for new NO-donor aspirin-like molecules: a new class of nitrooxy-acyl derivatives of salicylic acid

scientific article

Structural and biological characterization of new hybrid drugs joining an HDAC inhibitor to different NO-donors.

scientific article published on 15 December 2017

Structure-Activity Relationship Studies on Tetrahydroisoquinoline Derivatives: [4'-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl)biphenyl-4-ol] (MC70) Conjugated through Flexible Alkyl Chains with Furazan Moieties Gives Rise to Potent and Sel

scientific article

Structure-antioxidant activity relationships in a series of NO-donor phenols

scientific article published in September 2008

Studies of the potential genotoxic effects of furoxans: the case of CAS 1609 and of the water-soluble analogue of CHF 2363.

scientific article published on 13 February 2008

Synthesis and Biological Evaluation of the First Example of NO-Donor Histone Deacetylase Inhibitor

scientific article

Synthesis and antimalarial activities of some furoxan sulfones and related furazans.

scientific article published on 24 June 2005

Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis.

scientific article published on 21 July 2016

Synthesis and preliminary biological profile of new NO-donor tolbutamide analogues

scientific article published on 11 April 2012

Synthesis and preliminary pharmacological characterisation of a new class of nitrogen-containing bisphosphonates (N-BPs).

scientific article published in March 2010

Synthesis of NO-donor bisphosphonates and their in-vitro action on bone resorption.

scientific article published on March 2005

Synthesis of some novel organic nitrates and comparative in vitro study of their vasodilator profile

scientific article

Synthesis physicochemical profile and PAMPA study of new NO-donor edaravone co-drugs

scientific article published on 08 December 2011

Synthesis, chiral HPLC resolution and configuration assignment of 1-phenylglyceryl trinitrate stereomers

scientific article published on 01 June 2006

The Furoxan System: Design of Selective Nitric Oxide (NO) Donor Inhibitors of COX-2 Endowed with Anti-Aggregatory and Vasodilating Activities

scientific article published on 01 July 2005

Tuning the Hydrophobicity of a Mitochondria-Targeted NO Photodonor

scientific article published on 08 May 2018

Water-Soluble Nitric-Oxide-Releasing Acetylsalicylic Acid (ASA) Prodrugs

scientific article published on 10 June 2013

gem-Dinitroalkyl Benzenes: A Novel Class of IOP-Lowering Agents for the Treatment of Ocular Hypertension.

scientific article published on 13 September 2017

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