Search filters

List of works by Carlos Alfaro

A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C.

scientific article published on 4 March 2013

CD8 T cell priming in the presence of IFN-α renders CTLs with improved responsiveness to homeostatic cytokines and recall antigens: important traits for adoptive T cell therapy.

scientific article

Carcinoma-derived interleukin-8 disorients dendritic cell migration without impairing T-cell stimulation

scientific article

Cardiotrophin-1 determines liver engraftment of syngenic colon carcinoma cells through an immune system-mediated mechanism

scientific article published on December 2012

Cellular liaisons of natural killer lymphocytes in immunology and immunotherapy of cancer

scientific article published on May 2007

Clinical implications of antigen transfer mechanisms from malignant to dendritic cells. exploiting cross-priming.

scientific article

Dendritic cells adhere to and transmigrate across lymphatic endothelium in response to IFN-α

scientific article published on 27 October 2010

Dendritic cells delivered inside human carcinomas are sequestered by interleukin-8.

scientific article

Dendritic cells take up and present antigens from viable and apoptotic polymorphonuclear leukocytes

scientific article

Functional expression of CD137 (4-1BB) on T helper follicular cells.

scientific article

Immunogenic cell death and cross-priming are reaching the clinical immunotherapy arena

scientific article published on 01 April 2006

Improving efficacy of interleukin-12-transfected dendritic cells injected into murine colon cancer with anti-CD137 monoclonal antibodies and alloantigens.

scientific article published on May 2004

In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb.

scientific article

Influence of Interleukin-8 and Neutrophil Extracellular Trap (NET) Formation in the Tumor Microenvironment: Is There a Pathogenic Role?

scientific article published on 10 April 2019

Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primates

scientific article

Interleukin-15 liver gene transfer increases the number and function of IKDCs and NK cells.

scientific article published on 14 February 2008

Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas.

scientific article published on 14 December 2004

Intratumoral injection of interferon-α and systemic delivery of agonist anti-CD137 monoclonal antibodies synergize for immunotherapy.

scientific article published on January 2011

Intratumoural administration of dendritic cells: hostile environment and help by gene therapy

scientific article

Liver gene transfer of interkeukin-15 constructs that become part of circulating high density lipoproteins for immunotherapy

scientific article

Lymphatic endothelium forms integrin-engaging 3D structures during DC transit across inflamed lymphatic vessels

scientific article published on 25 March 2013

MAGE antigens: therapeutic targets in hepatocellular carcinoma?

scientific article published on 01 January 2004

Nivolumab and Urelumab Enhance Antitumor Activity of Human T Lymphocytes Engrafted in Rag2-/-IL2Rγnull Immunodeficient Mice.

scientific article published on 25 June 2015

Pilot clinical trial of type 1 dendritic cells loaded with autologous tumor lysates combined with GM-CSF, pegylated IFN, and cyclophosphamide for metastatic cancer patients.

scientific article published on 2 November 2011

Recombinant adenoviral vectors turn on the type I interferon system without inhibition of transgene expression and viral replication.

scientific article published on 19 April 2006

Serum interleukin-8 reflects tumor burden and treatment response across malignancies of multiple tissue origins.

scientific article published on 15 September 2014

Significance of the IL-8 pathway for immunotherapy

scientific article published on 20 December 2019

Specialized dendritic cells in cross-presentation of exogenous antigens to cytotoxic T lymphocytes

scientific article published in September 2013

The HIF-1α Hypoxia Response in Tumor-Infiltrating T Lymphocytes Induces Functional CD137 (4-1BB) for Immunotherapy

scientific article published on 19 June 2012

The combined actions of NK and T lymphocytes are necessary to reject an EGFP+ mesenchymal tumor through mechanisms dependent on NKG2D and IFN gamma.

scientific article published on September 2007

Therapeutic antitumor efficacy of anti-CD137 agonistic monoclonal antibody in mouse models of myeloma

scientific article published on November 2008

Paulina is supported by:

About Paulina

Help