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List of works by Paola Vergani

CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains

scientific article published on February 2005

Can two wrongs make a right? F508del-CFTR ion channel rescue by second-site mutations in its transmembrane domains

scientific article published on 21 January 2022

Complementation of a yeast delta pkc1 mutant by the Arabidopsis proteinANT.

scientific article published on January 1997

Conformational changes in the catalytically inactive nucleotide-binding site of CFTR.

scientific article published on 10 June 2013

Control of the CFTR channel's gates

scientific article published on November 2005

Discovery of Multitarget Agents Active as Broad-Spectrum Antivirals and Correctors of Cystic Fibrosis Transmembrane Conductance Regulator for Associated Pulmonary Diseases

scientific article

Electrophysiological, biochemical, and bioinformatic methods for studying CFTR channel gating and its regulation

scientific article published in January 2011

Extracellular K+ and Ba2+ mediate voltage-dependent inactivation of the outward-rectifying K+ channel encoded by the yeast gene TOK1.

scientific article published in April 1997

Fluorescence assay for simultaneous quantification of CFTR ion-channel function and plasma membrane proximity

scientific article published on 15 September 2020

Improved fluorescence assays to measure the defects associated with F508del-CFTR allow identification of new active compounds

scientific article

In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer

scientific article published on 12 October 2006

Increased apical Na+ permeability in cystic fibrosis is supported by a quantitative model of epithelial ion transport

scientific article published on 3 June 2013

Involvement of F1296 and N1303 of CFTR in induced-fit conformational change in response to ATP binding at NBD2 ⬇️

scientific article published on October 1, 2010

Multitarget CFTR Modulators Endowed with Multiple Beneficial Side Effects for Cystic Fibrosis Patients: Toward a Simplified Therapeutic Approach †

scientific article published on 03 December 2019

Mutant cycles at CFTR's non-canonical ATP-binding site support little interface separation during gating ⬇️

scientific article

Mutations in the pore regions of the yeast K+ channel YKC1 affect gating by extracellular K+.

scientific article published on December 1998

Mutations in the yeast two pore K+ channel YKC1 identify functional differences between the pore domains

scientific article published in September 1999

On the mechanism of MgATP-dependent gating of CFTR Cl- channels

scientific article

Potentiation of the cystic fibrosis transmembrane conductance regulator by VX-770 involves stabilization of the pre-hydrolytic, O state

scientific article published on 16 September 2018

Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating ⬇️

scientific article

Review. ATP hydrolysis-driven gating in cystic fibrosis transmembrane conductance regulator.

scientific article published on January 2009

STRUCTURE, GATING, AND REGULATION OF THE CFTR ANION CHANNEL

scientific article published on 01 January 2019

Strategies for cystic fibrosis transmembrane conductance regulator inhibition: from molecular mechanisms to treatment for secretory diarrhoeas

scientific article published on 28 October 2020

Strict coupling between CFTR's catalytic cycle and gating of its Cl- ion pore revealed by distributions of open channel burst durations.

scientific article

Structure of Transmembrane Helix 8 and Possible Membrane Defects in CFTR

article by Valentina Corradi et al published 24 April 2018 in Biophysical Journal

The ABC protein turned chloride channel whose failure causes cystic fibrosis

scientific article

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