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List of works by Tomasz Frączyk

A Functional Role for Aβ in Metal Homeostasis? N-Truncation and High-Affinity Copper Binding.

scientific article published on 14 July 2015

Altered mouse leukemia L1210 thymidylate synthase, associated with cell resistance to 5-fluoro-dUrd, is not mutated but rather reflects posttranslational modification

scientific article published on 27 February 2006

Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS.

scientific article published on 12 August 2017

Cu(II)‐Binding N‐Terminal Sequences of Human Proteins

scientific article published in 2021

Design and in vitro Characterization of Tricyclic Benzodiazepine Derivatives as Potent and Selective Anti-leukemic Agents

scientific article published on 24 November 2020

Developmental arrest in Caenorhabditis elegans dauer larvae causes high expression of enzymes involved in thymidylate biosynthesis, similar to that found in Trichinella muscle larvae.

scientific article

Diabetes-induced changes in glucose synthesis, intracellular glutathione status and hydroxyl free radical generation in rabbit kidney-cortex tubules

scientific article published in June 2004

Differential effects of vanadium, tungsten and molybdenum on inhibition of glucose formation in renal tubules and hepatocytes of control and diabetic rabbits: beneficial action of melatonin and N-acetylcysteine

scientific article published in June 2004

Effect of enzymatic hydrolysis on surface activity and surface rheology of type I collagen

scientific article published on 19 May 2015

Effect of surfactants on surface activity and rheological properties of type I collagen at air/water interface

scientific article

Electron capture dissociation mass spectrometric analysis of lysine-phosphorylated peptides.

scientific article published on December 2010

Gly-His-Thr-Asp-Amide, an Insulin-Activating Peptide from the Human Pancreas Is a Strong Cu(II) but a Weak Zn(II) Chelator

scientific article published on 27 November 2018

Human annexins A1, A2, and A8 as potential molecular targets for Ni(II) ions.

scientific article published on 20 October 2014

Interplay between Copper, Neprilysin, and N-Truncation of β-Amyloid

scientific article published on 18 May 2018

Mechanism of influence of phosphorylation on serine 124 on a decrease of catalytic activity of human thymidylate synthase

scientific article published on 9 April 2010

Melatonin attenuates diabetes-induced oxidative stress in rabbits

scientific article published in March 2006

Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme

New insights into interactions between the nucleotide-binding domain of CFTR and keratin 8.

scientific article

Ni(ii) ions cleave and inactivate human alpha-1 antitrypsin hydrolytically, implicating nickel exposure as a contributing factor in pathologies related to antitrypsin deficiency

scientific article published on April 2015

On the ability of CuAβ1-x peptides to form ternary complexes: Neurotransmitter glutamate is a competitor while not a ternary partner

scientific article published on 2 March 2016

Peptide Bond Cleavage by Ni(II) Ions within the Nuclear Localization Signal Sequence

scientific article published on 28 January 2020

Peptide bond cleavage in the presence of Ni-containing particles

scientific article published on 12 May 2020

Phosphorylation of basic amino acid residues in proteins: important but easily missed

scientific article published on May 27, 2011

Phosphorylation of thymidylate synthase affects slow-binding inhibition by 5-fluoro-dUMP and N(4)-hydroxy-dCMP.

scientific article

Phosphorylation of thymidylate synthase from various sources by human protein kinase CK2 and its catalytic subunits

scientific article

Properties of phosphorylated thymidylate synthase

scientific journal article

Revised coordination model and stability constants of Cu(II) complexes of tris buffer

scientific article published on 4 December 2013

Ternary Cu(II) Complex with GHK Peptide and Cis-Urocanic Acid as a Potential Physiologically Functional Copper Chelate

scientific article published on 27 August 2020

The Palladium(II) Complex of A<i>β</i><sub>4-16</sub> as Suitable Model for Structural Studies of Biorelevant Copper(II) Complexes of N-Truncated Beta-Amyloids

scientific article published on 02 December 2020

The Sub-picomolar Cu2+ Dissociation Constant of Human Serum Albumin

scientific article published on 29 October 2019

Thiophosphorylation of free amino acids and enzyme protein by thiophosphoramidate ions

scientific article published on 26 November 2009

Thymidylate synthase-catalyzed, tetrahydrofolate-dependent self-inactivation by 5-FdUMP

scientific article published on 11 September 2019

Tyrosine nitration affects thymidylate synthase properties.

scientific article

Unusual Zn(II) Affinities of Zinc Fingers of Poly(ADP-ribose)Polymerase 1 (PARP-1) Nuclear Protein

scientific article published on 30 December 2014

cis-Urocanic acid as a potential nickel(II) binding molecule in the human skin

scientific article published on 01 February 2014