List of works - Paola Cipriani

A genetic variation located in the promoter region of the UPAR (CD87) gene is associated with the vascular complications of systemic sclerosis

scientific article

A retrospective, multicenter study evaluating the prognostic value of minor salivary gland histology in a large cohort of patients with primary Sjögren's syndrome

scientific article published on 8 October 2014

Angiogenesis in rheumatoid arthritis: a disease specific process or a common response to chronic inflammation?

scientific article published on 27 April 2011

Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers

scientific article

Angiogenic cytokines and growth factors in systemic sclerosis.

scientific article

Association between a stromal cell-derived factor 1 (SDF-1/CXCL12) gene polymorphism and microvascular disease in systemic sclerosis.

scientific article

Association of psoriasis and/or psoriatic arthritis with autoimmune diseases: the experience of two Italian integrated Dermatology/Rheumatology outpatient clinics

scientific article

Biologic therapies and infections in the daily practice of three Italian rheumatologic units: a prospective, observational study.

scientific article

CD4(-)CD8(-) T-cells in primary Sjögren's syndrome: association with the extent of glandular involvement

scientific article

Cellular players in angiogenesis during the course of systemic sclerosis.

scientific article

Circulating gamma/delta T lymphocytes from systemic sclerosis (SSc) patients display a T helper (Th) 1 polarization

scientific article published on 01 August 2001

Combination therapy with cyclosporine and methotrexate in patients with early rheumatoid arthritis soon inhibits TNFalpha production without decreasing TNFalpha mRNA levels. An in vivo and in vitro study

scientific article published in May 2002

Comment on ‘Where are we going in the management of interstitial lung disease in patients with systemic sclerosis?’

scientific article published on 26 June 2015

Complement system and rheumatoid arthritis: relationships with autoantibodies, serological, clinical features, and anti-TNF treatment

scientific article published on 01 April 2011

Cyclophosphamide pulse regimen in the treatment of alveolitis in systemic sclerosis.

scientific article

Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry

scientific article

Differential expression of stromal cell-derived factor 1 and its receptor CXCR4 in the skin and endothelial cells of systemic sclerosis patients: Pathogenetic implications

scientific article published in September 2006

Early assessment of sub-clinical cardiac involvement in systemic sclerosis (SSc) using delayed enhancement cardiac magnetic resonance (CE-MRI).

scientific article

Efficacy of inhibition of IL-1 in patients with rheumatoid arthritis and type 2 diabetes mellitus: two case reports and review of the literature

scientific article published on 2 June 2015

Endothelial progenitor cells: Are they displaying a function in autoimmune disorders?

scientific article published on 3 May 2016

H-ferritin and CD68(+) /H-ferritin(+) monocytes/macrophages are increased in the skin of adult-onset Still's disease patients and correlate with the multi-visceral involvement of the disease.

scientific article published on 18 June 2016

High levels of NK cells in the peripheral blood of patients affected with anti-phospholipid syndrome and recurrent spontaneous abortion: a potential new hypothesis

scientific article published on 17 August 2007

IL-1β at the crossroad between rheumatoid arthritis and type 2 diabetes: may we kill two birds with one stone?

scientific article

Immunomodulation in psoriatic arthritis: focus on cellular and molecular pathways

scientific article

Impaired Cav-1 expression in SSc mesenchymal cells upregulates VEGF signaling: a link between vascular involvement and fibrosis

scientific article

Impaired endothelium-mesenchymal stem cells cross-talk in systemic sclerosis: a link between vascular and fibrotic features

scientific article

Impairment of endothelial cell differentiation from bone marrow-derived mesenchymal stem cells: new insight into the pathogenesis of systemic sclerosis

scientific article published on June 2007

Increase of circulating γ/δ T lymphocytes in the peripheral blood of patients affected by active inflammatory bowel disease

scientific article published on 01 October 1994

Increased level of H-ferritin and its imbalance with L-ferritin, in bone marrow and liver of patients with adult onset Still's disease, developing macrophage activation syndrome, correlate with the severity of the disease.

scientific article

Inhibition of the Complement System by Glutathione: Molecular Mechanisms and Potential Therapeutic Implications ⬇️

scientific article published on January 1, 2011

Interleukin (IL)-17-producing pathogenic T lymphocytes co-express CD20 and are depleted by rituximab in primary Sjögren's syndrome: a pilot study

scientific article published on 3 March 2016

Interleukin (IL)-22 receptor 1 is over-expressed in primary Sjogren's syndrome and Sjögren-associated non-Hodgkin lymphomas and is regulated by IL-18.

scientific article

Interleukin (IL)-9/IL-9R axis drives γδ T cells activation in psoriatic arthritis patients

scientific article published on 20 August 2016

Interleukin-9 Overexpression and Th9 Polarization Characterize the Inflamed Gut, the Synovial Tissue, and the Peripheral Blood of Patients With Psoriatic Arthritis

scientific article published on 01 August 2016

Interleukin-9 and T helper type 9 cells in rheumatic diseases.

scientific article published on 9 May 2016

International consensus: What else can we do to improve diagnosis and therapeutic strategies in patients affected by autoimmune rheumatic diseases (rheumatoid arthritis, spondyloarthritides, systemic sclerosis, systemic lupus erythematosus, antiphos

scientific article

Intravenous immunoglobulin therapy in pregnant patients affected with systemic lupus erythematosus and recurrent spontaneous abortion

scientific article

Is minor salivary gland biopsy more than a diagnostic tool in primary Sjo¨gren׳s syndrome? Association between clinical, histopathological, and molecular features: A retrospective study

scientific article published on 15 May 2014

Jejunoileal bypass as the main procedure in the onset of immune-related conditions: the model of BADAS.

scientific article published on May 2013

Long-Term Retention Rate of Anakinra in Adult Onset Still's Disease and Predictive Factors for Treatment Response

scientific article published on 02 April 2019

Long-term anti-TNF therapy and the risk of serious infections in a cohort of patients with rheumatoid arthritis: comparison of adalimumab, etanercept and infliximab in the GISEA registry

scientific article published on 13 July 2012

Low-dose oral imatinib in the treatment of systemic sclerosis interstitial lung disease unresponsive to cyclophosphamide: a phase II pilot study

scientific article

Macitentan inhibits the transforming growth factor-β profibrotic action, blocking the signaling mediated by the ETR/TβRI complex in systemic sclerosis dermal fibroblasts.

scientific article

Mesenchymal Stem Cell Transplantation in Systemic Sclerosis: Comment on the Article by Maria et al

scientific article published on 01 September 2016

Mesenchymal stem cells (MSCs) from scleroderma patients (SSc) preserve their immunomodulatory properties although senescent and normally induce T regulatory cells (Tregs) with a functional phenotype: implications for cellular-based therapy.

scientific article published in August 2013

Mesenchymal stromal cells and rheumatic diseases: new tools from pathogenesis to regenerative therapies.

scientific article

Methotrexate in rheumatoid arthritis: optimizing therapy among different formulations. Current and emerging paradigms.

scientific article

Methotrexate: an old new drug in autoimmune disease.

scientific article published on 22 September 2014

Monocytes from patients with rheumatoid arthritis and type 2 diabetes mellitus display an increased production of interleukin (IL)-1β via the nucleotide-binding domain and leucine-rich repeat containing family pyrin 3(NLRP3)-inflammasome activation:

scientific article published on 10 June 2015

Myositis in primary Sjögren's syndrome: data from a multicentre cohort.

scientific article

Nerve growth factor and neuropeptides circulating levels in systemic sclerosis (scleroderma)

scientific article

Perivascular Cells in Diffuse Cutaneous Systemic Sclerosis Overexpress Activated ADAM12 and Are Involved in Myofibroblast Transdifferentiation and Development of Fibrosis.

scientific article published in June 2016

Prescribing motivations and patients' characteristics related to the use of biologic drugs in adult-onset Still's disease: analysis of a multicentre "real-life" cohort

scientific article published on 01 July 2019

Resistance to apoptosis in circulating alpha/beta and gamma/delta T lymphocytes from patients with systemic sclerosis

scientific article published on 01 October 2006

Response to Interleukin-1 Inhibitors in 140 Italian Patients with Adult-Onset Still's Disease: A Multicentre Retrospective Observational Study

scientific article

Rituximab in primary Sjögren's syndrome: a ten-year journey.

scientific article

Rituximab modulates IL-17 expression in the salivary glands of patients with primary Sjögren’s syndrome

scientific article published on 06 March 2014

Rituximab modulates the expression of IL-22 in the salivary glands of patients with primary Sjogren's syndrome

scientific article published on 21 December 2012

Safety and efficacy of intra-articular anti-tumor necrosis factor α agents compared to corticosteroids in a treat-to-target strategy in patients with inflammatory arthritis and monoarthritis flare

scientific article published on 18 December 2015

Scleroderma Mesenchymal Stem Cells display a different phenotype from healthy controls; implications for regenerative medicine

scientific article

Searching for a good model for systemic sclerosis: the molecular profile and vascular changes occurring in UCD-200 chickens strongly resemble the early phase of human systemic sclerosis

scientific article published on July 2016

Serum levels of soluble CD30 are increased in ulcerative colitis (UC) but not in Crohn's disease (CD)

scientific article published on 01 March 1998

Stem cell therapies for systemic sclerosis.

scientific article

Stem cells in autoimmune diseases: Implications for pathogenesis and future trends in therapy.

scientific article

Surface Expression of Fractalkine Receptor (CX3CR1) on CD4+/CD28 T Cells in RA Patients and Correlation with Atherosclerotic Damage

scientific article published on 01 June 2007

T Regulatory and T Helper 17 Cells in Primary Sjögren's Syndrome: Facts and Perspectives

scientific article

The -670G>A polymorphism in the FAS gene promoter region influences the susceptibility to systemic sclerosis

article

The CD68(+)/H-ferritin(+) cells colonize the lymph nodes of the patients with adult onset Still's disease and are associated with increased extracellular level of H-ferritin in the same tissue: correlation with disease severity and implication for p

scientific article published on 5 November 2015

The Endothelial-mesenchymal Transition in Systemic Sclerosis Is Induced by Endothelin-1 and Transforming Growth Factor-β and May Be Blocked by Macitentan, a Dual Endothelin-1 Receptor Antagonist

scientific article published on 15 August 2015

The IL1-like cytokine IL33 and its receptor ST2 are abnormally expressed in the affected skin and visceral organs of patients with systemic sclerosis

scientific article published on 23 September 2009

The role of IL-1β in the bone loss during rheumatic diseases.

scientific article published on 12 April 2015

Tocilizumab for the treatment of adult-onset Still's disease: results from a case series.

scientific article published on 5 September 2013

Unmasking the pathogenic role of IL-17 axis in primary Sjögren's syndrome: a new era for therapeutic targeting?

scientific article published on 23 August 2014

Variations of neuronal nitric oxide synthase in systemic sclerosis skin

scientific article published on 01 January 2006

Where are we going in the management of interstitial lung disease in patients with systemic sclerosis?

scientific article

List of works by Paola Cipriani

A genetic variation located in the promoter region of the UPAR (CD87) gene is associated with the vascular complications of systemic sclerosis

A retrospective, multicenter study evaluating the prognostic value of minor salivary gland histology in a large cohort of patients with primary Sjögren's syndrome

Angiogenesis in rheumatoid arthritis: a disease specific process or a common response to chronic inflammation?

Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers

Angiogenic cytokines and growth factors in systemic sclerosis.

Association between a stromal cell-derived factor 1 (SDF-1/CXCL12) gene polymorphism and microvascular disease in systemic sclerosis.

Association of psoriasis and/or psoriatic arthritis with autoimmune diseases: the experience of two Italian integrated Dermatology/Rheumatology outpatient clinics

Biologic therapies and infections in the daily practice of three Italian rheumatologic units: a prospective, observational study.

CD4(-)CD8(-) T-cells in primary Sjögren's syndrome: association with the extent of glandular involvement

Cellular players in angiogenesis during the course of systemic sclerosis.

Circulating gamma/delta T lymphocytes from systemic sclerosis (SSc) patients display a T helper (Th) 1 polarization

Combination therapy with cyclosporine and methotrexate in patients with early rheumatoid arthritis soon inhibits TNFalpha production without decreasing TNFalpha mRNA levels. An in vivo and in vitro study

Comment on ‘Where are we going in the management of interstitial lung disease in patients with systemic sclerosis?’

Complement system and rheumatoid arthritis: relationships with autoantibodies, serological, clinical features, and anti-TNF treatment

Cyclophosphamide pulse regimen in the treatment of alveolitis in systemic sclerosis.

Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry

Differential expression of stromal cell-derived factor 1 and its receptor CXCR4 in the skin and endothelial cells of systemic sclerosis patients: Pathogenetic implications

Early assessment of sub-clinical cardiac involvement in systemic sclerosis (SSc) using delayed enhancement cardiac magnetic resonance (CE-MRI).

Efficacy of inhibition of IL-1 in patients with rheumatoid arthritis and type 2 diabetes mellitus: two case reports and review of the literature

Endothelial progenitor cells: Are they displaying a function in autoimmune disorders?

H-ferritin and CD68(+) /H-ferritin(+) monocytes/macrophages are increased in the skin of adult-onset Still's disease patients and correlate with the multi-visceral involvement of the disease.

High levels of NK cells in the peripheral blood of patients affected with anti-phospholipid syndrome and recurrent spontaneous abortion: a potential new hypothesis

IL-1β at the crossroad between rheumatoid arthritis and type 2 diabetes: may we kill two birds with one stone?

Immunomodulation in psoriatic arthritis: focus on cellular and molecular pathways

Impaired Cav-1 expression in SSc mesenchymal cells upregulates VEGF signaling: a link between vascular involvement and fibrosis

Impaired endothelium-mesenchymal stem cells cross-talk in systemic sclerosis: a link between vascular and fibrotic features

Impairment of endothelial cell differentiation from bone marrow-derived mesenchymal stem cells: new insight into the pathogenesis of systemic sclerosis

Increase of circulating γ/δ T lymphocytes in the peripheral blood of patients affected by active inflammatory bowel disease

Increased level of H-ferritin and its imbalance with L-ferritin, in bone marrow and liver of patients with adult onset Still's disease, developing macrophage activation syndrome, correlate with the severity of the disease.

Inhibition of the Complement System by Glutathione: Molecular Mechanisms and Potential Therapeutic Implications ⬇️

Interleukin (IL)-17-producing pathogenic T lymphocytes co-express CD20 and are depleted by rituximab in primary Sjögren's syndrome: a pilot study

Interleukin (IL)-22 receptor 1 is over-expressed in primary Sjogren's syndrome and Sjögren-associated non-Hodgkin lymphomas and is regulated by IL-18.

Interleukin (IL)-9/IL-9R axis drives γδ T cells activation in psoriatic arthritis patients

Interleukin-9 Overexpression and Th9 Polarization Characterize the Inflamed Gut, the Synovial Tissue, and the Peripheral Blood of Patients With Psoriatic Arthritis

Interleukin-9 and T helper type 9 cells in rheumatic diseases.

International consensus: What else can we do to improve diagnosis and therapeutic strategies in patients affected by autoimmune rheumatic diseases (rheumatoid arthritis, spondyloarthritides, systemic sclerosis, systemic lupus erythematosus, antiphos

Intravenous immunoglobulin therapy in pregnant patients affected with systemic lupus erythematosus and recurrent spontaneous abortion

Is minor salivary gland biopsy more than a diagnostic tool in primary Sjo¨gren׳s syndrome? Association between clinical, histopathological, and molecular features: A retrospective study

Jejunoileal bypass as the main procedure in the onset of immune-related conditions: the model of BADAS.

Long-Term Retention Rate of Anakinra in Adult Onset Still's Disease and Predictive Factors for Treatment Response

Long-term anti-TNF therapy and the risk of serious infections in a cohort of patients with rheumatoid arthritis: comparison of adalimumab, etanercept and infliximab in the GISEA registry

Low-dose oral imatinib in the treatment of systemic sclerosis interstitial lung disease unresponsive to cyclophosphamide: a phase II pilot study

Macitentan inhibits the transforming growth factor-β profibrotic action, blocking the signaling mediated by the ETR/TβRI complex in systemic sclerosis dermal fibroblasts.

Mesenchymal Stem Cell Transplantation in Systemic Sclerosis: Comment on the Article by Maria et al

Mesenchymal stem cells (MSCs) from scleroderma patients (SSc) preserve their immunomodulatory properties although senescent and normally induce T regulatory cells (Tregs) with a functional phenotype: implications for cellular-based therapy.

Mesenchymal stromal cells and rheumatic diseases: new tools from pathogenesis to regenerative therapies.

Methotrexate in rheumatoid arthritis: optimizing therapy among different formulations. Current and emerging paradigms.

Methotrexate: an old new drug in autoimmune disease.

Monocytes from patients with rheumatoid arthritis and type 2 diabetes mellitus display an increased production of interleukin (IL)-1β via the nucleotide-binding domain and leucine-rich repeat containing family pyrin 3(NLRP3)-inflammasome activation:

Myositis in primary Sjögren's syndrome: data from a multicentre cohort.

Nerve growth factor and neuropeptides circulating levels in systemic sclerosis (scleroderma)

Perivascular Cells in Diffuse Cutaneous Systemic Sclerosis Overexpress Activated ADAM12 and Are Involved in Myofibroblast Transdifferentiation and Development of Fibrosis.

Prescribing motivations and patients' characteristics related to the use of biologic drugs in adult-onset Still's disease: analysis of a multicentre "real-life" cohort

Resistance to apoptosis in circulating alpha/beta and gamma/delta T lymphocytes from patients with systemic sclerosis

Response to Interleukin-1 Inhibitors in 140 Italian Patients with Adult-Onset Still's Disease: A Multicentre Retrospective Observational Study

Rituximab in primary Sjögren's syndrome: a ten-year journey.

Rituximab modulates IL-17 expression in the salivary glands of patients with primary Sjögren’s syndrome

Rituximab modulates the expression of IL-22 in the salivary glands of patients with primary Sjogren's syndrome

Safety and efficacy of intra-articular anti-tumor necrosis factor α agents compared to corticosteroids in a treat-to-target strategy in patients with inflammatory arthritis and monoarthritis flare

Scleroderma Mesenchymal Stem Cells display a different phenotype from healthy controls; implications for regenerative medicine

Searching for a good model for systemic sclerosis: the molecular profile and vascular changes occurring in UCD-200 chickens strongly resemble the early phase of human systemic sclerosis

Serum levels of soluble CD30 are increased in ulcerative colitis (UC) but not in Crohn's disease (CD)

Stem cell therapies for systemic sclerosis.

Stem cells in autoimmune diseases: Implications for pathogenesis and future trends in therapy.

Surface Expression of Fractalkine Receptor (CX3CR1) on CD4+/CD28 T Cells in RA Patients and Correlation with Atherosclerotic Damage

T Regulatory and T Helper 17 Cells in Primary Sjögren's Syndrome: Facts and Perspectives

The -670G>A polymorphism in the FAS gene promoter region influences the susceptibility to systemic sclerosis

The CD68(+)/H-ferritin(+) cells colonize the lymph nodes of the patients with adult onset Still's disease and are associated with increased extracellular level of H-ferritin in the same tissue: correlation with disease severity and implication for p

The Endothelial-mesenchymal Transition in Systemic Sclerosis Is Induced by Endothelin-1 and Transforming Growth Factor-β and May Be Blocked by Macitentan, a Dual Endothelin-1 Receptor Antagonist

The IL1-like cytokine IL33 and its receptor ST2 are abnormally expressed in the affected skin and visceral organs of patients with systemic sclerosis

The role of IL-1β in the bone loss during rheumatic diseases.

Tocilizumab for the treatment of adult-onset Still's disease: results from a case series.

Unmasking the pathogenic role of IL-17 axis in primary Sjögren's syndrome: a new era for therapeutic targeting?

Variations of neuronal nitric oxide synthase in systemic sclerosis skin

Where are we going in the management of interstitial lung disease in patients with systemic sclerosis?