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List of works by Sebastian Hoffmann

"ToxRTool", a new tool to assess the reliability of toxicological data

scientific article

1.2 Aspects of test assessment

scientific article published on 01 February 2009

A feasibility study developing an integrated testing strategy assessing skin irritation potential of chemicals

scientific article published on 21 May 2008

A primer on systematic reviews in toxicology.

scientific article

A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing - t4 report*.

scientific article published on January 2012

Adaptation of the Systematic Review Framework to the Assessment of Toxicological Test Methods: Challenges and Lessons Learned with the Zebrafish Embryotoxicity Test

scientific article published on 13 June 2018

Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics ⬇️

scientific article published on February 10, 2012

Categorization of chemicals according to their relative human skin sensitizing potency

scientific article published on January 2014

ECVAM prevalidation of three cell transformation assays ⬇️

scientific article published on January 1, 2011

ECVAM prevalidation study on in vitro cell transformation assays: General outline and conclusions of the study ⬇️

scientific article published on November 26, 2011

Effects of BPA in snails

scientific article published on June 2006

Estimation of acute oral toxicity using the No Observed Adverse Effect Level (NOAEL) from the 28 day repeated dose toxicity studies in rats

scientific article published on 14 October 2008

Evidence-Based Toxicology

scientific article published in January 2016

Exposure of 19 substances to lung A549 cells at the air liquid interface or under submerged conditions reveals high correlation between cytotoxicity in vitro and CLP classifications for acute lung toxicity

scientific article published on 17 September 2019

Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review.

scientific article

Implementing systematic review techniques in chemical risk assessment: Challenges, opportunities and recommendations

scientific article (publication date: 2016)

Instruments for assessing risk of bias and other methodological criteria of animal studies: omission of well-established methods.

scientific article published on March 2014

Integrated Testing Strategies (ITS) for safety assessment.

scientific article published on 19 November 2014

Integrated Testing Strategy (ITS) – Opportunities to better use existing data and guide future testing in toxicology ⬇️

scientific article published on January 1, 2010

LLNA variability: An essential ingredient for a comprehensive assessment of non-animal skin sensitization test methods and strategies

scientific article published on 13 July 2015

Mechanistic validation.

scientific article published on January 2013

Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database

scientific article published on 23 February 2018

Non-animal methods to predict skin sensitization (II): an assessment of defined approaches *.

scientific article published on 23 February 2018

Prospective multicentre study of the U-SENS test method for skin sensitization testing

scientific article published on 3 October 2015

Protocol for designing INVITES-IN, a tool for assessing the internal validity of in vitro studies

Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods

scientific article published on 28 December 2013

Round robin study to evaluate the reconstructed human epidermis (RhE) model as an in vitro skin irritation test for detection of irritant activity in medical device extracts

scientific article published on 8 January 2018

Simple clotting test to detect procoagulant abdominal swabs

scientific article published on 11 February 2015

State-of-the-art and new options to assess T cell activation by skin sensitizers: Cosmetics Europe Workshop.

scientific article published on 2 October 2017

Systematic evaluation of non-animal test methods for skin sensitisation safety assessment

scientific article

The Emergence of Systematic Review in Toxicology

scientific article published on 05 May 2016

The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds ⬇️

scientific article published on 14 May 2020

The HaCaT/THP-1 Cocultured Activation Test (COCAT) for skin sensitization: a study of intra-lab reproducibility and predictivity

scientific article published on 27 May 2019

Toward Good In Vitro Reporting Standards

scientific article published on 01 January 2019

Use of the Cultex® Radial Flow System as an in vitro exposure method to assess acute pulmonary toxicity of fine dusts and nanoparticles with special focus on the intra- and inter-laboratory reproducibility.

scientific article published on 11 May 2013

Validation of the 3D Skin Comet assay using full thickness skin models: Transferability and reproducibility.

scientific article published on 10 January 2018

Validation of the CULTEX® Radial Flow System for the assessment of the acute inhalation toxicity of airborne particles

scientific article published on 16 March 2019

Validation study on the Ocular Irritection assay for eye irritation testing

scientific article published on 15 March 2014

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