Search filters

List of works by Mark C. Williams

A ruthenium dimer complex with a flexible linker slowly threads between DNA bases in two distinct steps.

scientific article

A single amino acid substitution in ORF1 dramatically decreases L1 retrotransposition and provides insight into nucleic acid chaperone activity.

scientific article published on 12 September 2008

A single zinc finger optimizes the DNA interactions of the nucleocapsid protein of the yeast retrotransposon Ty3.

scientific article

Accurate nanoscale flexibility measurement of DNA and DNA-protein complexes by atomic force microscopy in liquid

scientific article published in August 2017

Basic N-Terminus of Yeast Nhp6A Regulates the Mechanism of Its DNA Flexibility Enhancement ⬇️

scientific article published on December 13, 2011

Biophysical characterization of DNA binding from single molecule force measurements

scientific article

C-terminal domain modulates the nucleic acid chaperone activity of human T-cell leukemia virus type 1 nucleocapsid protein via an electrostatic mechanism

scientific article

DNA Intercalation Facilitates Efficient DNA-Targeted Covalent Binding of Phenanthriplatin

scientific article published on 17 January 2019

DNA bridging and looping by HMO1 provides a mechanism for stabilizing nucleosome-free chromatin

scientific article

DNA intercalation optimized by two-step molecular lock mechanism

scientific article

DNA overstretching in the presence of glyoxal: structural evidence of force-induced DNA melting.

scientific article published on 18 April 2008

DNA stretching as a probe for nucleic acid interactions: Reply to Comments on "Biophysical characterization of DNA binding from single molecule force measurements" by Kathy R. Chaurasiya, Thayaparan Paramanathan, Micah J. McCauley, Mark C. Williams

scientific article published on September 2010

Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G.

scientific article

Differential contribution of basic residues to HIV-1 nucleocapsid protein's nucleic acid chaperone function and retroviral replication

scientific article

Dimerization regulates both deaminase-dependent and deaminase-independent HIV-1 restriction by APOBEC3G.

scientific article published on 19 September 2017

Dissecting the Dynamic Pathways of Stereoselective DNA Threading Intercalation

scientific article

Exploring the interaction of ruthenium(II) polypyridyl complexes with DNA using single-molecule techniques.

scientific article

First passage time of N excluded-volume particles on a line

scientific article published on 17 October 2005

Force spectroscopy reveals the DNA structural dynamics that govern the slow binding of Actinomycin D

scientific article

HIV restriction factor APOBEC3G binds in multiple steps and conformations to search and deaminate single-stranded DNA

scientific article published on 18 December 2019

HMGB binding to DNA: single and double box motifs

scientific journal article

Interaction of bacteriophage T4 and T7 single-stranded DNA-binding proteins with DNA.

scientific article

Introduction to Special Issue "The 11th International Retroviral Nucleocapsid and Assembly Symposium"

scientific article published on 31 October 2020

Kinetic regulation of single DNA molecule denaturation by T4 gene 32 protein structural domains.

scientific article

Kinetics and thermodynamics of salt-dependent T7 gene 2.5 protein binding to single- and double-stranded DNA

scientific article published on 4 September 2008

L1 retrotransposition requires rapid ORF1p oligomerization, a novel coiled coil-dependent property conserved despite extensive remodeling

scientific article

LINE-1 retrotransposition requires the nucleic acid chaperone activity of the ORF1 protein

scientific article published in May 2005

Mapping the phase diagram of single DNA molecule force-induced melting in the presence of ethidium

scientific article published on 06 October 2005

Measuring DNA–Protein Binding Affinity on a Single Molecule Using Optical Tweezers ⬇️

scientific article published on January 1, 2011

Mechanical measurement of single-molecule binding rates: kinetics of DNA helix-destabilization by T4 gene 32 protein

scientific article published in February 2004

Mechanical properties of base-modified DNA are not strictly determined by base stacking or electrostatic interactions

scientific article

Mechanically manipulating the DNA threading intercalation rate

scientific article published in March 2008

Mechanism for nucleic acid chaperone activity of HIV-1 nucleocapsid protein revealed by single molecule stretching.

scientific article

Mechanism of DNA flexibility enhancement by HMGB proteins.

scientific article published on 07 January 2009

Mechanisms of small molecule-DNA interactions probed by single-molecule force spectroscopy.

scientific article published on 16 April 2016

Mechanistic differences between HIV-1 and SIV nucleocapsid proteins and cross-species HIV-1 genomic RNA recognition

scientific article published on 29 December 2016

Modulation of T4 gene 32 protein DNA binding activity by the recombination mediator protein UvsY.

scientific article published on 24 May 2008

Oligomerization transforms human APOBEC3G from an efficient enzyme to a slowly dissociating nucleic acid-binding protein.

scientific article

Optical tweezers experiments resolve distinct modes of DNA-protein binding.

scientific article published on April 2009

Paired mutations abolish and restore the balanced annealing and melting activities of ORF1p that are required for LINE-1 retrotransposition ⬇️

scientific article published on March 26, 2011

Peeling back the mystery of DNA overstretching.

scientific article published on 21 October 2009

Polymerase manager protein UmuD directly regulates Escherichia coli DNA polymerase III binding to ssDNA ⬇️

scientific article published on July 30, 2013

Quantifying DNA-protein interactions by single molecule stretching

article

Quantifying force-dependent and zero-force DNA intercalation by single-molecule stretching

scientific article published on 29 April 2007

Rapid kinetics of protein-nucleic acid interaction is a major component of HIV-1 nucleocapsid protein's nucleic acid chaperone function

article

Reshaping the Energy Landscape Transforms the Mechanism and Binding Kinetics of DNA Threading Intercalation

scientific article

Retroviral nucleocapsid proteins display nonequivalent levels of nucleic acid chaperone activity

scientific article published on 06 August 2008

Salt dependent binding of T4 gene 32 protein to single and double-stranded DNA: single molecule force spectroscopy measurements

scientific article published on 9 April 2005

Significant Differences in RNA Structure Destabilization by HIV-1 GagDp6 and NCp7 Proteins ⬇️

scientific article published on 25 April 2020

Single DNA molecule stretching measures the activity of chemicals that target the HIV-1 nucleocapsid protein.

scientific article

Single molecule force spectroscopy of salt-dependent bacteriophage T7 gene 2.5 protein binding to single-stranded DNA

scientific article published on 17 October 2006

Single-molecule biophysics: untying a nanoscale knot

scientific article published on 23 September 2011

Single-molecule kinetics reveal microscopic mechanism by which High-Mobility Group B proteins alter DNA flexibility.

scientific article published on 9 November 2012

Single-molecule mechanochemical characterization of E. coli pol III core catalytic activity.

scientific article published on 6 March 2017

Single-molecule stretching studies of RNA chaperones.

scientific article

Single-molecule studies of high-mobility group B architectural DNA bending proteins

scientific article

Specific zinc-finger architecture required for HIV-1 nucleocapsid protein's nucleic acid chaperone function

scientific article

Stimulated-emission cross sections and nonradiative relaxation of the L56' state of trivalent americium in fluorozirconate glass

scientific article published on 01 March 1992

Strong DNA deformation required for extremely slow DNA threading intercalation by a binuclear ruthenium complex

scientific article

Stuffing a virus with DNA: dissecting viral genome packaging.

scholarly article

Target search of N sliding proteins on a DNA

scientific article

Thermodynamics of DNA interactions from single molecule stretching experiments.

scientific article

Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter.

scientific article published on 26 July 2017

Paulina is supported by:

About Paulina

Help