List of works - William Mullen

A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI.

scientific article

A distinct urinary biomarker pattern characteristic of female Fabry patients that mirrors response to enzyme replacement therapy

scientific article

A structural basis for the inhibition of collagen-stimulated platelet function by quercetin and structurally related flavonoids

scientific article

A urinary proteome-based classifier for the early detection of decline in glomerular filtration

scientific article published on 6 July 2016

Absorption, disposition, metabolism, and excretion of [3-(14)C]caffeic acid in rats

scientific article

Absorption, excretion and metabolite profiling of methyl-, glucuronyl-, glucosyl- and sulpho-conjugates of quercetin in human plasma and urine after ingestion of onions

scientific article published on 01 July 2006

Absorption, metabolism, and excretion of cider dihydrochalcones in healthy humans and subjects with an ileostomy

scientific article published in March 2009

Absorption, metabolism, and excretion of green tea flavan-3-ols in humans with an ileostomy

scientific article published in March 2010

Analysis of ellagitannins and conjugates of ellagic acid and quercetin in raspberry fruits by LC-MSn

scientific article published in September 2003

Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease

scientific article

Bioavailability and metabolism of orange juice flavanones in humans: impact of a full-fat yogurt.

scientific article

Bioavailability of C-linked dihydrochalcone and flavanone glucosides in humans following ingestion of unfermented and fermented rooibos teas.

scientific article

Bioavailability of [2-(14)C]quercetin-4'-glucoside in rats

scientific article

Bioavailability of anthocyanins and ellagitannins following consumption of raspberries by healthy humans and subjects with an ileostomy.

scientific article published in April 2010

Bioavailability of multiple components following acute ingestion of a polyphenol-rich juice drink

scientific article published in July 2010

Bioavailability of pelargonidin-3-O-glucoside and its metabolites in humans following the ingestion of strawberries with and without cream.

scientific article

CE-MS-based proteomics in biomarker discovery and clinical application

scientific article

Cerebrospinal fluid prohormone processing and neuropeptides stimulating feed intake of dairy cows during early lactation.

scientific article published on 14 January 2015

Clinical proteomics in obstetrics and neonatology

scientific article published on 03 January 2014

Comparative Analysis of Label-Free and 8-Plex iTRAQ Approach for Quantitative Tissue Proteomic Analysis

scientific article

Comparison of CE-MS/MS and LC-MS/MS sequencing demonstrates significant complementarity in natural peptide identification in human urine

scientific article published on 20 November 2013

Comparison of Depletion Strategies for the Enrichment of Low-Abundance Proteins in Urine

scientific article published on 24 July 2015

Comparison of higher energy collisional dissociation and collision-induced dissociation MS/MS sequencing methods for identification of naturally occurring peptides in human urine

scientific article published on June 2015

Detection of urinary biomarkers in reservoir hosts of leptospirosis by capillary electrophoresis-mass spectrometry

scientific article

Determination of flavonol metabolites in plasma and tissues of rats by HPLC-radiocounting and tandem mass spectrometry following oral ingestion of [2-(14)C]quercetin-4'-glucoside.

scientific article published in November 2002

Development of a MALDI MS-based platform for early detection of acute kidney injury

scientific article published on 27 April 2016

Diagnosis and Prediction of CKD Progression by Assessment of Urinary Peptides

scientific article published on 14 January 2015

Diagnosis of subclinical and clinical acute T-cell-mediated rejection in renal transplant patients by urinary proteome analysis

scientific article published on 29 April 2011

Dietary antioxidants, lipid peroxidation and plumage colouration in nestling blue tits Cyanistes caeruleus

scientific article published on 14 September 2010

Discovery and validation of urinary biomarkers for detection of renal cell carcinoma

scientific article published on 25 December 2013

Distribution and biosynthesis of flavan-3-ols in Camellia sinensis seedlings and expression of genes encoding biosynthetic enzymes.

scientific article published on 25 February 2010

Effect of freezing and storage on the phenolics, ellagitannins, flavonoids, and antioxidant capacity of red raspberries.

scientific article

Ellagitannins, flavonoids, and other phenolics in red raspberries and their contribution to antioxidant capacity and vasorelaxation properties

scientific article published in August 2002

Evaluation of phenolic compounds in commercial fruit juices and fruit drinks.

scientific article

Flavonoid and hydroxycinnamate profiles of english apple ciders

scientific article published on 15 September 2007

Green tea flavan-3-ols: colonic degradation and urinary excretion of catabolites by humans.

scientific article published in January 2010

High-Throughput LC-MS/MS Proteomic Analysis of a Mouse Model of Mesiotemporal Lobe Epilepsy Predicts Microglial Activation Underlying Disease Development

scientific article

Human urinary peptide database for multiple disease biomarker discovery

scientific article published on 18 May 2011

IMAC fractionation in combination with LC-MS reveals H2B and NIF-1 peptides as potential bladder cancer biomarkers

scientific article published on 21 August 2013

Identification of ageing-associated naturally occurring peptides in human urine

scientific article published on 29 September 2015

Identification of metabolites in human plasma and urine after consumption of a polyphenol-rich juice drink

scientific article published in February 2010

Identification of proanthocyanidin dimers and trimers, flavone C-Glycosides, and antioxidants in Ficus deltoidea , a malaysian herbal tea

scientific article published on 24 January 2011

Identification of urinary peptide biomarkers associated with rheumatoid arthritis

scientific article

Integrative analysis of extracellular and intracellular bladder cancer cell line proteome with transcriptome: improving coverage and validity of -omics findings

scientific article published on 11 May 2016

Long term metabolic syndrome induced by a high fat high fructose diet leads to minimal renal injury in C57BL/6 mice

scientific article (publication date: 2013)

Molecular Changes in Tissue Proteome during Prostate Cancer Development: Proof-of-Principle Investigation

scientific article published on 31 August 2020

Multicentre prospective validation of a urinary peptidome-based classifier for the diagnosis of type 2 diabetic nephropathy

scientific article

New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis

scientific article

Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis

scientific article published on 5 October 2016

Occurrence of flavonols in tomatoes and tomato-based products

scientific article published on 01 July 2000

Oenology: red wine procyanidins and vascular health

scientific article

On-line high-performance liquid chromatography analysis of the antioxidant activity of phenolic compounds in green and black tea.

scientific article published in January 2005

Peptide fingerprinting of Alzheimer's disease in cerebrospinal fluid: identification and prospective evaluation of new synaptic biomarkers

scientific article

Performance of different separation methods interfaced in the same MS-reflection TOF detector: a comparison of performance between CE versus HPLC for biomarker analysis

scientific article

Potassium deficiency induces the biosynthesis of oxylipins and glucosinolates in Arabidopsis thaliana

scientific article

Proteome-based systems biology analysis of the diabetic mouse aorta reveals major changes in fatty acid biosynthesis as potential hallmark in diabetes mellitus-associated vascular disease

scientific article published on 26 February 2014

Proteomic Analysis of Vitreous Humor in Retinal Vein Occlusion

scientific article

Proteomic candidate biomarkers of drug-induced nephrotoxicity in the rat

scientific article (publication date: 2012)

Proteomics of vitreous humor of patients with exudative age-related macular degeneration

scientific article

Recent advances in capillary electrophoresis coupled to mass spectrometry for clinical proteomic applications ⬇️

scientific article published on 08 May 2013

Tea prepared from Anastatica hirerochuntica seeds contains a diversity of antioxidant flavonoids, chlorogenic acids and phenolic compounds.

scientific article published on 20 December 2010

The absorption, metabolism and excretion of flavan-3-ols and procyanidins following the ingestion of a grape seed extract by rats.

scientific article

The influence of moderate red wine consumption on antioxidant status and indices of oxidative stress associated with CHD in healthy volunteers

scientific article published in February 2005

Urinary Peptide Analysis Differentiates Pancreatic Cancer From Chronic Pancreatitis

article

Urinary proteomic biomarkers for diagnosis and risk stratification of autosomal dominant polycystic kidney disease: a multicentric study

scientific article

Urinary proteomic biomarkers to predict cardiovascular events

article

Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups

scientific article published on 16 January 2017

Urinary proteomics in obstructive sleep apnoea and obesity.

scientific article published in November 2014

Urinary proteomics in the assessment of chronic kidney disease

scientific article

Urinary proteomics to support diagnosis of stroke

scientific article

Urine proteome analysis in heart failure with reduced ejection fraction complicated by chronic kidney disease: feasibility, and clinical and pathogenetic correlates

scientific article published on 25 May 2016

Use of accurate mass full scan mass spectrometry for the analysis of anthocyanins in berries and berry-fed tissues

scientific article published in April 2010

Variations in the profile and content of anthocyanins in wines made from cabernet sauvignon and hybrid grapes

scientific article published in July 2002

Yoghurt impacts on the excretion of phenolic acids derived from colonic breakdown of orange juice flavanones in humans.

scientific article published in May 2009

List of works by William Mullen

A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI.

A distinct urinary biomarker pattern characteristic of female Fabry patients that mirrors response to enzyme replacement therapy

A structural basis for the inhibition of collagen-stimulated platelet function by quercetin and structurally related flavonoids

A urinary proteome-based classifier for the early detection of decline in glomerular filtration

Absorption, disposition, metabolism, and excretion of [3-(14)C]caffeic acid in rats

Absorption, excretion and metabolite profiling of methyl-, glucuronyl-, glucosyl- and sulpho-conjugates of quercetin in human plasma and urine after ingestion of onions

Absorption, metabolism, and excretion of cider dihydrochalcones in healthy humans and subjects with an ileostomy

Absorption, metabolism, and excretion of green tea flavan-3-ols in humans with an ileostomy

Analysis of ellagitannins and conjugates of ellagic acid and quercetin in raspberry fruits by LC-MSn

Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease

Bioavailability and metabolism of orange juice flavanones in humans: impact of a full-fat yogurt.

Bioavailability of C-linked dihydrochalcone and flavanone glucosides in humans following ingestion of unfermented and fermented rooibos teas.

Bioavailability of [2-(14)C]quercetin-4'-glucoside in rats

Bioavailability of anthocyanins and ellagitannins following consumption of raspberries by healthy humans and subjects with an ileostomy.

Bioavailability of multiple components following acute ingestion of a polyphenol-rich juice drink

Bioavailability of pelargonidin-3-O-glucoside and its metabolites in humans following the ingestion of strawberries with and without cream.

CE-MS-based proteomics in biomarker discovery and clinical application

Cerebrospinal fluid prohormone processing and neuropeptides stimulating feed intake of dairy cows during early lactation.

Clinical proteomics in obstetrics and neonatology

Comparative Analysis of Label-Free and 8-Plex iTRAQ Approach for Quantitative Tissue Proteomic Analysis

Comparison of CE-MS/MS and LC-MS/MS sequencing demonstrates significant complementarity in natural peptide identification in human urine

Comparison of Depletion Strategies for the Enrichment of Low-Abundance Proteins in Urine

Comparison of higher energy collisional dissociation and collision-induced dissociation MS/MS sequencing methods for identification of naturally occurring peptides in human urine

Detection of urinary biomarkers in reservoir hosts of leptospirosis by capillary electrophoresis-mass spectrometry

Determination of flavonol metabolites in plasma and tissues of rats by HPLC-radiocounting and tandem mass spectrometry following oral ingestion of [2-(14)C]quercetin-4'-glucoside.

Development of a MALDI MS-based platform for early detection of acute kidney injury

Diagnosis and Prediction of CKD Progression by Assessment of Urinary Peptides

Diagnosis of subclinical and clinical acute T-cell-mediated rejection in renal transplant patients by urinary proteome analysis

Dietary antioxidants, lipid peroxidation and plumage colouration in nestling blue tits Cyanistes caeruleus

Discovery and validation of urinary biomarkers for detection of renal cell carcinoma

Distribution and biosynthesis of flavan-3-ols in Camellia sinensis seedlings and expression of genes encoding biosynthetic enzymes.

Effect of freezing and storage on the phenolics, ellagitannins, flavonoids, and antioxidant capacity of red raspberries.

Ellagitannins, flavonoids, and other phenolics in red raspberries and their contribution to antioxidant capacity and vasorelaxation properties

Evaluation of phenolic compounds in commercial fruit juices and fruit drinks.

Flavonoid and hydroxycinnamate profiles of english apple ciders

Green tea flavan-3-ols: colonic degradation and urinary excretion of catabolites by humans.

High-Throughput LC-MS/MS Proteomic Analysis of a Mouse Model of Mesiotemporal Lobe Epilepsy Predicts Microglial Activation Underlying Disease Development

Human urinary peptide database for multiple disease biomarker discovery

IMAC fractionation in combination with LC-MS reveals H2B and NIF-1 peptides as potential bladder cancer biomarkers

Identification of ageing-associated naturally occurring peptides in human urine

Identification of metabolites in human plasma and urine after consumption of a polyphenol-rich juice drink

Identification of proanthocyanidin dimers and trimers, flavone C-Glycosides, and antioxidants in Ficus deltoidea , a malaysian herbal tea

Identification of urinary peptide biomarkers associated with rheumatoid arthritis

Integrative analysis of extracellular and intracellular bladder cancer cell line proteome with transcriptome: improving coverage and validity of -omics findings

Long term metabolic syndrome induced by a high fat high fructose diet leads to minimal renal injury in C57BL/6 mice

Molecular Changes in Tissue Proteome during Prostate Cancer Development: Proof-of-Principle Investigation

Multicentre prospective validation of a urinary peptidome-based classifier for the diagnosis of type 2 diabetic nephropathy

New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis

Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis

Occurrence of flavonols in tomatoes and tomato-based products

Oenology: red wine procyanidins and vascular health

On-line high-performance liquid chromatography analysis of the antioxidant activity of phenolic compounds in green and black tea.

Peptide fingerprinting of Alzheimer's disease in cerebrospinal fluid: identification and prospective evaluation of new synaptic biomarkers

Performance of different separation methods interfaced in the same MS-reflection TOF detector: a comparison of performance between CE versus HPLC for biomarker analysis

Potassium deficiency induces the biosynthesis of oxylipins and glucosinolates in Arabidopsis thaliana

Proteome-based systems biology analysis of the diabetic mouse aorta reveals major changes in fatty acid biosynthesis as potential hallmark in diabetes mellitus-associated vascular disease

Proteomic Analysis of Vitreous Humor in Retinal Vein Occlusion

Proteomic candidate biomarkers of drug-induced nephrotoxicity in the rat

Proteomics of vitreous humor of patients with exudative age-related macular degeneration

Recent advances in capillary electrophoresis coupled to mass spectrometry for clinical proteomic applications ⬇️

Tea prepared from Anastatica hirerochuntica seeds contains a diversity of antioxidant flavonoids, chlorogenic acids and phenolic compounds.

The absorption, metabolism and excretion of flavan-3-ols and procyanidins following the ingestion of a grape seed extract by rats.

The influence of moderate red wine consumption on antioxidant status and indices of oxidative stress associated with CHD in healthy volunteers

Urinary Peptide Analysis Differentiates Pancreatic Cancer From Chronic Pancreatitis

Urinary proteomic biomarkers for diagnosis and risk stratification of autosomal dominant polycystic kidney disease: a multicentric study

Urinary proteomic biomarkers to predict cardiovascular events

Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups

Urinary proteomics in obstructive sleep apnoea and obesity.

Urinary proteomics in the assessment of chronic kidney disease

Urinary proteomics to support diagnosis of stroke

Urine proteome analysis in heart failure with reduced ejection fraction complicated by chronic kidney disease: feasibility, and clinical and pathogenetic correlates

Use of accurate mass full scan mass spectrometry for the analysis of anthocyanins in berries and berry-fed tissues

Variations in the profile and content of anthocyanins in wines made from cabernet sauvignon and hybrid grapes

Yoghurt impacts on the excretion of phenolic acids derived from colonic breakdown of orange juice flavanones in humans.