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List of works by Siu-Hong Chan

A type IV modification-dependent restriction enzyme SauUSI from Staphylococcus aureus subsp. aureus USA300

scientific article

Analysis of the GTPase activity and active sites of the NG domains of FtsY and Ffh from Streptomyces coelicolor

scientific article published in July 2006

Asymmetric DNA recognition by the OkrAI endonuclease, an isoschizomer of BamHI

scientific article published on September 9, 2010

Catalytic domain of restriction endonuclease BmrI as a cleavage module for engineering endonucleases with novel substrate specificities

scientific article

Characterization and crystal structure of the type IIG restriction endonuclease RM.BpuSI

scientific article

Cloning of Nt.CviQII nicking endonuclease and its cognate methyltransferase: M.CviQII methylates AG sequences.

scientific article published on 25 April 2006

Cofactor requirement of HpyAV restriction endonuclease

scientific article (publication date: 5 February 2010)

Crystal structure of the restriction-modification system control element C.Bcll and mapping of its binding site

scientific article published in December 2005

Crystallization and preliminary crystallographic analysis of a novel orange fluorescent protein from the Cnidaria tube anemone Cerianthus sp.

scientific article published on 23 January 2004

Discovery of natural nicking endonucleases Nb.BsrDI and Nb.BtsI and engineering of top-strand nicking variants from BsrDI and BtsI.

scientific article published on 22 June 2007

Elimination of inter-domain interactions increases the cleavage fidelity of the restriction endonuclease DraIII

scientific article

Engineering BspQI nicking enzymes and application of N.BspQI in DNA labeling and production of single-strand DNA.

scientific article

Engineering Nt.BtsCI and Nb.BtsCI nicking enzymes and applications in generating long overhangs.

scientific article

Expression and purification of BmrI restriction endonuclease and its N-terminal cleavage domain variants

scientific article

Fusion core structure of the severe acute respiratory syndrome coronavirus (SARS-CoV): in search of potent SARS-CoV entry inhibitors

scientific article published in August 2008

Increasing cleavage specificity and activity of restriction endonuclease KpnI.

scientific article published on 19 August 2013

Natural and engineered nicking endonucleases--from cleavage mechanism to engineering of strand-specificity

scientific article

Natural and engineered nicking endonucleases—from cleavagemechanism to engineering of strand-specificity

Solution structure and thermal stability of ribosomal protein L30e from hyperthermophilic archaeon Thermococcus celer

scientific article

Structural basis of RNA cap modification by SARS-CoV-2

scientific article published on 24 July 2020

Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I

scientific article published on 12 June 2015

Structural insights into the assembly and shape of Type III restriction-modification (R-M) EcoP15I complex by small-angle X-ray scattering.

scientific article published on 02 May 2012

Structure determination and biochemical characterization of a putative HNH endonuclease from Geobacter metallireducens GS-15

scientific article (publication date: 2013)

Targeting DNA 5mCpG sites with chimeric endonucleases

scientific article

The role of the methyltransferase domain of bifunctional restriction enzyme RM.BpuSI in cleavage activity

scientific article

Traceless splicing enabled by substrate-induced activation of the Nostoc punctiforme Npu DnaE intein after mutation of a catalytic cysteine to serine

scientific article published on 6 November 2014