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List of works by Laura M Sly

1alpha,25-dihydroxyvitamin D(3)-induced myeloid cell differentiation is regulated by a vitamin D receptor-phosphatidylinositol 3-kinase signaling complex

scientific article published on December 1999

A Low Carbohydrate, High Protein Diet Slows Tumor Growth and Prevents Cancer Initiation

scientific article published on 14 June 2011

A7 PI3KP110δ DRIVES INTESTINAL FIBROSIS IN SHIP DEFICIENT MICE

A80 MALT1 BLOCKS IL-1β-MEDIATED INTESTINAL INFLAMMATION

A94 SHIP-MICROBIOME INTERACTIONS IN INTESTINAL INFLAMMATION

Activity of SHIP, Which Prevents Expression of Interleukin 1β, Is Reduced in Patients With Crohn's Disease.

scientific article published on 16 October 2015

Alternative activation of macrophages by IL-4 requires SHIP degradation.

scientific article

Arginase activity in alternatively activated macrophages protects PI3Kp110δ deficient mice from dextran sodium sulfate induced intestinal inflammation

scientific article published on 25 September 2014

Assessment of Antibody-based Drugs Effects on Murine Bone Marrow and Peritoneal Macrophage Activation.

scientific article published on 26 December 2017

CD47-ligation induced cell death in T-acute lymphoblastic leukemia.

scientific article

Combined immunodeficiency associated with homozygous MALT1 mutations

scientific article published on 12 December 2013

Compositional changes to the ileal microbiome precede the onset of spontaneous ileitis in SHIP deficient mice

scientific article published on 13 February 2019

Depletion and Reconstitution of Macrophages in Mice

scientific article published on 01 January 2019

Depletion and reconstitution of macrophages in mice

scientific article published on August 2012

Derivation and characterization of murine alternatively activated (M2) macrophages

scientific article

Endosomal pH modulation by peptide-gold nanoparticle hybrids enables potent anti-inflammatory activity in phagocytic immune cells

scientific article published on 3 October 2016

Generation and characterization of murine alternatively activated macrophages

scientific article

IFN-γ directly inhibits murine B-cell precursor leukemia-initiating cell proliferation early in life.

scientific article published on 15 March 2017

IVIg and LPS Co-stimulation Induces IL-10 Production by Human Monocytes, Which Is Compromised by an FcγRIIA Disease-Associated Gene Variant

article

IgE-induced mast cell survival requires the prolonged generation of reactive oxygen species

scientific article published on September 2008

Impaired NLRP3 inflammasome activity during fetal development regulates IL-1β production in human monocytes

scientific article published on 17 November 2014

Inflammatory Bowel Disease and Immunonutrition: Novel Therapeutic Approaches Through Modulation of Diet and the Gut Microbiome.

scientific article

Integrins and ERp57 Coordinate to Regulate Cell Surface Calreticulin in Immunogenic Cell Death

scientific article published on 28 May 2019

Intravenous immunoglobulin (IVIg) or IVIg-treated macrophages reduce DSS-induced colitis by inducing macrophage IL-10 production

scientific article published on 17 May 2019

Intravenous immunoglobulin skews macrophages to an anti-inflammatory, IL-10-producing activation state

scientific article

LPS-Induced Upregulation of SHIP Is Essential for Endotoxin Tolerance

scientific article published on 01 August 2004

Linkage of Meis1 leukemogenic activity to multiple downstream effectors including Trib2 and Ccl3.

scientific article

Malt1 blocks IL-1β production by macrophages in vitro and limits dextran sodium sulfate-induced intestinal inflammation in vivo

scientific article published on 14 June 2018

Malt1 deficient mice develop osteoporosis independent of osteoclast-intrinsic effects of Malt1 deficiency

scientific article published on 16 July 2019

Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal.

scientific article

Monocyte p110alpha phosphatidylinositol 3-kinase regulates phagocytosis, the phagocyte oxidase, and cytokine production

scientific article published on 16 March 2007

Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML.

scientific article

Phosphatase regulation of macrophage activation

scientific article published on 24 July 2015

Phosphatidylinositol 3-kinase p110δ drives intestinal fibrosis in SHIP deficiency

scientific article published on 29 July 2019

Re: The Terminology Issue for Myeloid-Derived Suppressor Cells

scientific article published on 01 April 2007

Reconstitution of glucose uptake and chemotaxis in Pseudomonas aeruginosa glucose transport defective mutants

scientific article published on 01 November 1993

SHIP negatively regulates type II immune responses in mast cells and macrophages

scientific article published on 17 January 2018

SHIP prevents lipopolysaccharide from triggering an antiviral response in mice

scientific article published on 12 January 2009

SHIP regulates the reciprocal development of T regulatory and Th17 cells

scientific article

SHIP represses Th2 skewing by inhibiting IL-4 production from basophils

scientific article published on 3 December 2010

SHIP represses the generation of IL-3-induced M2 macrophages by inhibiting IL-4 production from basophils.

scientific article published on 26 August 2009

SHIP represses the generation of alternatively activated macrophages

scientific article

SHIP, SHIP2, and PTEN activities are regulated in vivo by modulation of their protein levels: SHIP is up-regulated in macrophages and mast cells by lipopolysaccharide.

scientific article published on December 2003

SHIP-deficient, alternatively activated macrophages protect mice during DSS-induced colitis

scientific article published on 17 June 2011

Salmonella enterica serovar Typhimurium periplasmic superoxide dismutases SodCI and SodCII are required for protection against the phagocyte oxidative burst

scientific article published on September 2002

Survival of Mycobacterium tuberculosis in Host Macrophages Involves Resistance to Apoptosis Dependent upon Induction of Antiapoptotic Bcl-2 Family Member Mcl-1

scientific article published on 01 January 2003

The 19-kDa Mycobacterium tuberculosis protein induces macrophage apoptosis through Toll-like receptor-2

scientific article

The Crohn's disease-associated polymorphism in ATG16L1 (rs2241880) reduces SHIP gene expression and activity in human subjects.

scientific article published on 30 July 2015

The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia

scientific article published on August 2006

The inositol phosphatase SHIP controls Salmonella enterica serovar Typhimurium infection in vivo

scientific article published on 21 April 2008

The p110α and p110β isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cells

scientific article

The role of SHIP in cytokine-induced signaling ⬇️

scientific article published on April 12, 2003

The role of SHIP1 in macrophage programming and activation.

scientific article published in November 2004

Tyrosine phosphorylation of SHIP promotes its proteasomal degradation.

scientific article published on 18 March 2010

α-Integrin expression and function modulates presentation of cell surface calreticulin.

scientific article published on 16 June 2016

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