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List of works by Brian L Black

A p38 MAPK-MEF2C pathway regulates B-cell proliferation

scientific journal article

A single mutation causes a spectrum of cardiovascular defects: the potential role of genetic modifiers, epigenetic influences, and stochastic events in phenotypic variability

scientific article published on 07 December 2005

An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation

scientific article

An arterial-specific enhancer of the human endothelin converting enzyme 1 (ECE1) gene is synergistically activated by Sox17, FoxC2, and Etv2.

scientific article published on 30 August 2014

An endoderm-specific transcriptional enhancer from the mouse Gata4 gene requires GATA and homeodomain protein-binding sites for function in vivo.

scientific article published on October 2009

BMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve development

scientific journal article

Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism

scientific journal article

Cardiovascular development and survival require Mef2c function in the myocardial but not the endothelial lineage

scientific article published on 03 December 2018

ChIP-Seq identification of weakly conserved heart enhancers

scientific article

Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants

scientific article

Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors

scientific article

Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE

scientific article published on 11 May 2021

Control of ribosomal protein synthesis by the Microprocessor complex

scientific article published on 23 February 2021

Cooperative activation of cardiac transcription through myocardin bridging of paired MEF2 sites

scientific article

Determinants of myogenic specificity within MyoD are required for noncanonical E box binding

scientific article published on 11 June 2007

Development of the endocardium

scientific article

Developmental biology: Diversity in the lymphatic vasculature

scientific article published in June 2015

Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer

scientific article

Endothelin signaling activates Mef2c expression in the neural crest through a MEF2C-dependent positive-feedback transcriptional pathway.

scientific article

FGF-dependent regulation of VEGF receptor 2 expression in mice ⬇️

scientific article published on July 1, 2011

GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium.

scientific article published on 30 June 2008

Gata4 expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element

scientific journal article

HRC is a direct transcriptional target of MEF2 during cardiac, skeletal, and arterial smooth muscle development in vivo

scientific article

Hand2 function in second heart field progenitors is essential for cardiogenesis.

scientific article

Identification and characterization of proximal promoter polymorphisms in the human concentrative nucleoside transporter 2 (SLC28A2).

scientific article published on 19 December 2008

Identification of novel Fgf enhancers and their role in dental evolution

scientific article

Isl1 is a direct transcriptional target of Forkhead transcription factors in second-heart-field-derived mesoderm.

scientific article published on 4 July 2009

Large-scale discovery of enhancers from human heart tissue

scientific article published on 4 December 2011

MEF2B is a potent transactivator expressed in early myogenic lineages

scientific journal article

Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins

scientific article published on 13 May 2009

Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development

scientific article published on 14 July 2004

Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells

scientific article published on 17 March 2015

Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor

scientific journal article

Multiple roles for the MyoD basic region in transmission of transcriptional activation signals and interaction with MEF2

scientific article published in January 1998

Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation

scientific journal article

Myocyte enhancer factor 2C function in skeletal muscle is required for normal growth and glucose metabolism in mice.

scientific article

N-twist, an evolutionarily conserved bHLH protein expressed in the developing CNS, functions as a transcriptional inhibitor

scientific journal article

NFATc1 controls skeletal muscle fiber type and is a negative regulator of MyoD activity

scientific article

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.

scientific article published on 31 January 2017

Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium

scientific journal article

Regulation of endothelial and hematopoietic development by the ETS transcription factor Etv2.

scientific article published on May 2012

Reptilian heart development and the molecular basis of cardiac chamber evolution

scientific journal article

Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling

scientific journal article

Specification of the mouse cardiac conduction system in the absence of Endothelin signaling

scientific article published on 19 July 2014

TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3

scientific article

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

scientific article (publication date: May 2005)

The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10

scientific article

The heart's Da Vinci code: a Renaissance at Keystone

scientific article published on 29 March 2007

The mouse MRF4 promoter is trans-activated directly and indirectly by muscle-specific transcription factors.

scientific article published on February 1995

The myogenic regulatory gene Mef2 is a direct target for transcriptional activation by Twist during Drosophila myogenesis

scientific article

The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field

scientific article

The transcription factor MEF2C is required for craniofacial development

scientific article

Transcription factor pathways and congenital heart disease.

scientific article published on January 2012

Transcription factor protein interactomes reveal genetic determinants in heart disease

scientific article published in March 2022

Transcriptional control of endothelial cell development.

scientific article

Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins

scientific article

Transgenic mice that express Cre recombinase under control of a skeletal muscle-specific promoter from mef2c

scientific article published in May 2005

Venous endothelin modulates responsiveness of cardiac sympathetic axons to arterial semaphorin

scientific article published on 08 February 2019

Vesicular stomatitis virus matrix protein inhibits host cell-directed transcription of target genes in vivo ⬇️

scientific article published on July 1, 1992

mef2c is activated directly by myogenic basic helix-loop-helix proteins during skeletal muscle development in vivo

scientific article

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