List of works - Cathryn L. Haigh

A 2-Substituted 8-Hydroxyquinoline Stimulates Neural Stem Cell Proliferation by Modulating ROS Signalling.

scientific article published on 21 June 2016

A Functional Role for Aβ in Metal Homeostasis? N-Truncation and High-Affinity Copper Binding.

scientific article published on 14 July 2015

Anionic phospholipid interactions of the prion protein N terminus are minimally perturbing and not driven solely by the octapeptide repeat domain

scientific article published on 2 August 2010

Blood vessel cell death during prion disease: implications for disease management and infection control.

scientific article published on 16 July 2014

Cavitation during the protein misfolding cyclic amplification (PMCA) method--The trigger for de novo prion generation?

scientific article published on 17 April 2015

Cerebral organoids as a new model for prion disease

publication published on 21 July 2021

Copper, endoproteolytic processing of the prion protein and cell signalling.

scientific article published on June 2010

Copper-dependent co-internalization of the prion protein and glypican-1.

scientific article published on September 2006

Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection.

scientific article published on 04 April 2013

Dominant roles of the polybasic proline motif and copper in the PrP23-89-mediated stress protection response.

scientific article published on 21 April 2009

Endoproteolytic cleavage as a molecular switch regulating and diversifying prion protein function.

scientific article published on February 2016

Increased proportions of C1 truncated prion protein protect against cellular M1000 prion infection

scientific article published on October 2009

Investigation of PrPC metabolism and function in live cells : methods for studying individual cells and cell populations

scientific article published in January 2008

MEK1 transduces the prion protein N2 fragment antioxidant effects

scientific article

Near-infrared fluorescence imaging of apoptotic neuronal cell death in a live animal model of prion disease

scientific article

Neuronal maturation reduces the type I IFN response to orthobunyavirus infection and leads to increased apoptosis of human neurons

scientific article published on 18 November 2019

Neutron reflectometry studies define prion protein N-terminal peptide membrane binding

scientific article

Optical imaging detects apoptosis in the brain and peripheral organs of prion-infected mice

scientific article published in February 2011

Pathogenic Prion Protein Isoforms Are Not Present in Cerebral Organoids Generated from Asymptomatic Donors Carrying the E200K Mutation Associated with Familial Prion Disease

scientific article published on 18 June 2020

PrPC-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site.

scientific article

Prion protein N1 cleavage peptides stimulate microglial interaction with surrounding cells

scientific article published on 20 April 2020

Prion protein cleavage fragments regulate adult neural stem cell quiescence through redox modulation of mitochondrial fission and SOD2 expression

scientific article published in September 2018

Prion protein reduces both oxidative and non-oxidative copper toxicity

scientific article published in August 2006

Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrPres level disparity.

scientific article

Regulation of prion protein expression by noncoding regions of the Prnp gene

scientific article published on 6 March 2007

Simplified Murine 3D Neuronal Cultures for Investigating Neuronal Activity and Neurodegeneration

scientific article published on 28 October 2016

Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids.

scientific article published on 14 June 2019

The Prion Protein N1 and N2 Cleavage Fragments Bind to Phosphatidylserine and Phosphatidic Acid; Relevance to Stress-Protection Responses

scientific article published on 7 August 2015

The prion protein regulates beta-amyloid-mediated self-renewal of neural stem cells in vitro.

scientific article

Using our mini-brains: cerebral organoids as an improved cellular model for human prion disease

scientific article published on 01 June 2020

List of works by Cathryn L. Haigh

A 2-Substituted 8-Hydroxyquinoline Stimulates Neural Stem Cell Proliferation by Modulating ROS Signalling.

A Functional Role for Aβ in Metal Homeostasis? N-Truncation and High-Affinity Copper Binding.

Anionic phospholipid interactions of the prion protein N terminus are minimally perturbing and not driven solely by the octapeptide repeat domain

Blood vessel cell death during prion disease: implications for disease management and infection control.

Cavitation during the protein misfolding cyclic amplification (PMCA) method--The trigger for de novo prion generation?

Cerebral organoids as a new model for prion disease

Copper, endoproteolytic processing of the prion protein and cell signalling.

Copper-dependent co-internalization of the prion protein and glypican-1.

Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection.

Dominant roles of the polybasic proline motif and copper in the PrP23-89-mediated stress protection response.

Endoproteolytic cleavage as a molecular switch regulating and diversifying prion protein function.

Increased proportions of C1 truncated prion protein protect against cellular M1000 prion infection

Investigation of PrPC metabolism and function in live cells : methods for studying individual cells and cell populations

MEK1 transduces the prion protein N2 fragment antioxidant effects

Near-infrared fluorescence imaging of apoptotic neuronal cell death in a live animal model of prion disease

Neuronal maturation reduces the type I IFN response to orthobunyavirus infection and leads to increased apoptosis of human neurons

Neutron reflectometry studies define prion protein N-terminal peptide membrane binding

Optical imaging detects apoptosis in the brain and peripheral organs of prion-infected mice

Pathogenic Prion Protein Isoforms Are Not Present in Cerebral Organoids Generated from Asymptomatic Donors Carrying the E200K Mutation Associated with Familial Prion Disease

PrPC-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site.

Prion protein N1 cleavage peptides stimulate microglial interaction with surrounding cells

Prion protein cleavage fragments regulate adult neural stem cell quiescence through redox modulation of mitochondrial fission and SOD2 expression

Prion protein reduces both oxidative and non-oxidative copper toxicity

Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrPres level disparity.

Regulation of prion protein expression by noncoding regions of the Prnp gene

Simplified Murine 3D Neuronal Cultures for Investigating Neuronal Activity and Neurodegeneration

Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids.

The Prion Protein N1 and N2 Cleavage Fragments Bind to Phosphatidylserine and Phosphatidic Acid; Relevance to Stress-Protection Responses

The prion protein regulates beta-amyloid-mediated self-renewal of neural stem cells in vitro.

Using our mini-brains: cerebral organoids as an improved cellular model for human prion disease