Search filters

List of works by Yuri Utkin

"Weak toxin" from Naja kaouthia is a nontoxic antagonist of alpha 7 and muscle-type nicotinic acetylcholine receptors

scientific article

?-Conotoxin analogs with additional positive charge show increased selectivity towards Torpedo�californica and some neuronal subtypes of nicotinic acetylcholine receptors

scientific article published on 05 September 2006

A comparative study on selectivity of alpha-conotoxins GI and ImI using their synthetic analogues and derivatives

scientific article published in April 2003

A model for short alpha-neurotoxin bound to nicotinic acetylcholine receptor from Torpedo californica: comparison with long-chain alpha-neurotoxins and alpha-conotoxins

scientific article

A new class of photoactivatable and cleavable derivatives of neurotoxin II from Naja naja oxiana. Synthesis, characterisation, and application for affinity labelling of the nicotinic acetylcholine receptor from Torpedo californica

scientific article published in March 1995

A new type of thrombin inhibitor, noncytotoxic phospholipase A2, from the Naja haje cobra venom

scientific article published on 19 July 2009

Activation of α7 Nicotinic Acetylcholine Receptor Upregulates HLA-DR and Macrophage Receptors: Potential Role in Adaptive Immunity and in Preventing Immunosuppression

scientific article published on 27 March 2020

An unusual phospholipase A₂ from puff adder Bitis arietans venom--a novel blocker of nicotinic acetylcholine receptors

scientific article

Analysis of nociceptive effects of neurotoxic phospholipase A2 from Vipera nikolskii venom in mice ⬇️

scientific article published on March 15, 2013

Anticoagulant Activity of Low-Molecular Weight Compounds from Heterometrus laoticus Scorpion Venom

scientific article published on 26 October 2017

Antiproliferative activity of cobra venom cytotoxins.

scientific article

Antiviral Effects of Animal Toxins: Is There a Way to Drugs?

scientific article published in 2022

Aromatic substitutions in alpha-conotoxin ImI. Synthesis of iodinated photoactivatable derivative

scientific article published in December 1999

Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor.

scientific article

Azemiopsin, a Selective Peptide Antagonist of Muscle Nicotinic Acetylcholine Receptor: Preclinical Evaluation as a Local Muscle Relaxant

scientific article published on 7 January 2018

Bacterial expression, NMR, and electrophysiology analysis of chimeric short/long-chain alpha-neurotoxins acting on neuronal nicotinic receptors

scientific article

Bacterial production and refolding from inclusion bodies of a "weak" toxin, a disulfide rich protein.

scientific article

Behavioural effects in mice and intoxication symptomatology of weak neurotoxin from cobra Naja kaouthia

scientific article

Benzophenone-type photoactivatable derivatives of alpha-neurotoxins and alpha-conotoxins in studies on Torpedo nicotinic acetylcholine receptor

scientific article published on 01 January 1999

Cancer cell injury by cytotoxins from cobra venom is mediated through lysosomal damage

scientific article

Central loop of non-conventional toxin WTX from Naja kaouthia is important for interaction with nicotinic acetylcholine receptors.

scientific article published on 22 June 2016

Cobra venom contains a pool of cysteine-rich secretory proteins.

scientific article

Cobra venom contains a protein belongs to the CRISP family

scientific article published in May 2001

Comparative analysis of membranotropic properties of various phospholipases A2 from venom of snakes of the family viperidae

scientific article

Comparative study of structure and activity of cytotoxins from venom of the cobras Naja oxiana, Naja kaouthia, and Naja haje.

scientific article published in October 2004

Computer modeling of binding of diverse weak toxins to nicotinic acetylcholine receptors

scientific article published on 23 February 2007

Conformational Studies of Neurotoxin II from Naja naja oxiana. Selective N-Acylation, Circular Dichroism and Nuclear-Magnetic-Resonance Study of Acylation Products

scientific article published on March 1, 1979

Cysteine-rich venom proteins from the snakes of Viperinae subfamily - molecular cloning and phylogenetic relationship

scientific article published on 12 November 2008

Detection of alpha7 nicotinic acetylcholine receptors with the aid of antibodies and toxins.

scientific article published on 12 January 2007

Direct Cloning of a Target Gene from a Pool of Homologous Sequences: Complete cDNA Sequence of a Weak Neurotoxin from Cobra Naja kaouthia ⬇️

scientific article published on January 1, 2003

Diversity of nicotinic receptors mediating Cl- current in Lymnaea neurons distinguished with specific agonists and antagonist

scientific article published on 30 October 2004

EPR And fluorescence study of interaction ofNaja naja oxiananeurotoxin II and its derivatives with acetylcholine receptor protein fromTorpedo marmorata ⬇️

scientific article published on October 1, 1979

ESR study of the interaction of cytotoxin II with model membranes

scientific article published in March 2001

Effects of snake venom polypeptides on central nervous system

scientific article

Efficient synthesis of natural alpha-conotoxins and their analogs

scientific article

First tryptophan-containing weak neurotoxin from cobra venom.

scientific article

Functional nicotinic acetylcholine receptors are expressed in B lymphocyte-derived cell lines

scientific article published in October 2003

Functions, structures and Triton X-100 effect for the catalytic subunits of heterodimeric phospholipases A2 from Vipera nikolskii venom.

scientific article

Heterodimeric V. nikolskii phospholipases A2 induce aggregation of the lipid bilayer

scientific article published on 17 May 2017

Heterodimeric neurotoxic phospholipases A2--the first proteins from venom of recently established species Vipera nikolskii: implication of venom composition in viper systematics

scientific article published on 09 November 2007

Hetlaxin, a new toxin from the Heterometrus laoticus scorpion venom, interacts with voltage-gated potassium channel Kv1.3.

scientific article published in March 2013

Inhibition of nicotinic acetylcholine receptors, a novel facet in the pleiotropic activities of snake venom phospholipases A2.

scientific article published on 18 December 2014

Inhibition of the nicotinic acetylcholine receptors by cobra venom α-neurotoxins: is there a perspective in lung cancer treatment?

scientific article

Interaction of the P-type cardiotoxin with phospholipid membranes.

scientific article

Interaction of three-finger proteins from snake venoms and from mammalian brain with the cys-loop receptors and their models.

scientific article published on May 2016

Interaction of three-finger toxins with phospholipid membranes: comparison of S- and P-type cytotoxins.

scientific article published on May 2005

Intracellular domains of the delta-subunits of Torpedo and rat acetylcholine receptors--expression, purification, and characterization

scientific article published in December 2004

Investigation of ligand-binding sites of the acetylcholine receptor using photoactivatable derivatives of neurotoxin II from Naja naja oxiana

scientific article published in September 1992

Isolation and preliminary crystallographic studies of two new phospholipases A2 from Vipera nikolskii venom

scientific article published on 8 January 2005

Labeling of Torpedo californica nicotinic acetylcholine receptor subunits by cobratoxin derivatives with photoactivatable groups of different chemical nature at Lys23

scientific article published on 01 April 1998

Mapping the functional topography of a receptor

scientific article published on 01 October 1992

Muscarinic toxin-like proteins from cobra venom

scientific article published on 01 December 2000

NU-120596, a Positive Allosteric Modulator of Mammalian α7 Nicotinic Acetylcholine Receptor, is a Negative Modulator of Ligand-Gated Chloride-Selective Channels of the Gastropod Lymnaea stagnalis

scientific article published on 04 April 2020

Naja melanoleuca cobra venom contains two forms of complement-depleting factor (CVF).

scientific article

Nanoencapsulation Enhances Anticoagulant Activity of Adenosine and Dipeptide IleTrp

scientific article published on 23 August 2019

Natural compounds interacting with nicotinic acetylcholine receptors: from low-molecular weight ones to peptides and proteins.

scientific article published on 14 May 2015

Naturally occurring disulfide-bound dimers of three-fingered toxins: a paradigm for biological activity diversification

scientific article

Nerve growth factor from cobra venom inhibits the growth of Ehrlich tumor in mice.

scientific article published on 26 February 2014

Neurotoxins from snake venoms and α-conotoxin ImI inhibit functionally active ionotropic γ-aminobutyric acid (GABA) receptors

scientific article published on 28 July 2015

Nicotinic acetylcholine receptors alpha4beta2 and alpha7 regulate myelo- and erythropoiesis within the bone marrow.

scientific article

Nicotinic receptors in Lymnaea stagnalis neurons are blocked by alpha-neurotoxins from cobra venoms

scientific article published in August 2001

Non-lethal polypeptide components in cobra venom.

scientific article published on January 2007

Nonconventional three-finger toxin BMLCL from krait Bungarus multicinctus venom with high affinity interacts with nicotinic acetylcholine receptors.

scientific article published on September 2015

Novel Bradykinin-Potentiating Peptides and Three-Finger Toxins from Viper Venom: Combined NGS Venom Gland Transcriptomics and Quantitative Venom Proteomics of the Azemiops feae Viper

scientific article published on 28 July 2020

Novel antagonists of nicotinic acetylcholine receptors--proteins from venoms of Viperidae snakes

scientific article published on 05 May 2015

Novel long-chain neurotoxins from Bungarus candidus distinguish the two binding sites in muscle-type nicotinic acetylcholine receptors

scientific article published on 26 April 2019

Oxiagin from the Naja oxiana cobra venom is the first reprolysin inhibiting the classical pathway of complement

scientific article published on 8 January 2005

Pancreatic and snake venom presynaptically active phospholipases A2 inhibit nicotinic acetylcholine receptors

scientific article published on 12 October 2017

Phospholipase A2 from krait Bungarus fasciatus venom induces human cancer cell death in vitro

scientific article published on 03 December 2019

Phospholipases a2 from Viperidae snakes: Differences in membranotropic activity between enzymatically active toxin and its inactive isoforms

scientific article published on 4 November 2014

Photoactivatable analogues of alpha-conotoxins GI and MI and their interaction with nicotinic acetylcholine receptor

scientific article published in March 2002

Photolabeling reveals the proximity of the alpha-neurotoxin binding site to the M2 helix of the ion channel in the nicotinic acetylcholine receptor.

scientific article

Physicochemical and immunological studies of the N-terminal domain of the Torpedo acetylcholine receptor alpha-subunit expressed in Escherichia coli.

scientific article

Polyclonal antibodies against native weak toxin Naja kaouthia discriminate native weak toxins and some other three-fingered toxins against their denaturated forms

scientific article published on 01 July 2005

Polypeptide and peptide toxins, magnifying lenses for binding sites in nicotinic acetylcholine receptors.

scientific article published on 06 June 2009

Pr-SNTX, a short-chain three-finger toxin from Papuan pigmy mulga snake, is an antagonist of muscle-type nicotinic acetylcholine receptor (α2βδε).

scientific article published on 25 July 2015

Proton-Nuclear-Magnetic-Resonance Study of the Conformation of Neurotoxin II from Middle-Asian Cobra (Naja naja oxiana) Venom ⬇️

scientific article published on December 11, 1976

Quantitative Proteomic Analysis of Venoms from Russian Vipers of Pelias Group: Phospholipases A₂ are the Main Venom Components

scientific article (publication date: 12 April 2016)

Quantitative proteomic analysis of Vietnamese krait venoms: Neurotoxins are the major components in Bungarus multicinctus and phospholipases A2 in Bungarus fasciatus

scientific article

Relationship between the binding sites for an alpha-conotoxin and snake venom neurotoxins in the nicotinic acetylcholine receptor from Torpedo californica

scientific article published on 01 September 1994

Reverse-phase chromatography isolation and MALDI mass spectrometry of the acetylcholine receptor subunits.

scientific article

Scorpion toxins interact with nicotinic acetylcholine receptors

scientific article published on 18 July 2019

Screening Snake Venoms for Toxicity to Tetrahymena Pyriformis Revealed Anti-Protozoan Activity of Cobra Cytotoxins

scientific article published on 15 May 2020

Sensitive nonradioactive screening method for compounds interacting with alpha7-cholinoreceptor

scientific article published in July 2003

Snake cytotoxins bind to membranes via interactions with phosphatidylserine head groups of lipids

scientific article

Spatial Structure and Activity of Synthetic Fragments of Lynx1 and of Nicotinic Receptor Loop C Models

scientific article published on 22 December 2020

Spatial structure of the M3 transmembrane segment of the nicotinic acetylcholine receptor α subunit ⬇️

scientific article published on July 15, 1998

Steered molecular dynamics simulations of cobra cytotoxin interaction with zwitterionic lipid bilayer: no penetration of loop tips into membranes

scientific article published on 18 July 2008

Structural Insight into Specificity of Interactions between Nonconventional Three-finger Weak Toxin from Naja kaouthia (WTX) and Muscarinic Acetylcholine Receptors

scientific article published on 4 August 2015

Substance P derivatives with photoactivatable labels in the N-terminal part of the molecule

scientific article published in December 1997

Synthesis of nitrodiazirinyl derivatives of neurotoxin II from Naja naja oxiana and their interaction with the Torpedo californica nicotinic acetylcholine receptor

scientific article published on 01 May 1995

The handedness of the subunit arrangement of the nicotinic acetylcholine receptor from Torpedo californica

scientific article published on 01 December 1995

The new peptide from the Fea's viper Azemiops feae venom interacts with nicotinic acetylcholine receptors

scientific article published on 01 January 2012

The weak neurotoxin from Naja kaouthia Cobra venom decreases the arterial blood pressure in rats

scientific article published in May 2001

Three-finger proteins from snakes and humans acting on nicotinic receptors: old and new

scientific article published on 10 July 2020

Three-finger toxins, a deadly weapon of elapid venom – Milestones of discovery ⬇️

scientific article published on September 18, 2012

Toxicity of cobra venom components to cockroach Gromphadorhina portentosa

scientific article published in October 2002

Toxicity of venoms from vipers of Pelias group to crickets Gryllus assimilis and its relation to snake entomophagy

scientific article published on 6 February 2007

Two forms of nerve growth factor from cobra venom prevent the death of PC12 cells in serum-free medium

scientific article published on 01 February 2001

Venoms of kraits Bungarus multicinctus and Bungarus fasciatus contain anticoagulant proteins

scientific article published on 13 March 2015

Vietnamese Heterometrus laoticus scorpion venom: evidence for analgesic and anti-inflammatory activity and isolation of new polypeptide toxin acting on Kv1.3 potassium channel.

scientific article

Weak neurotoxin from Naja kaouthia cobra venom affects haemodynamic regulation by acting on acetylcholine receptors

scientific article

Weak toxin WTX from Naja kaouthia cobra venom interacts with both nicotinic and muscarinic acetylcholine receptors

scientific article published on 4 August 2009

[Molecular cloning and analysis of cDNA sequences encoding serine proteinase and Kunitz type inhibitor in venom gland of Vipera nikolskii viper]

scientific article published on 01 May 2011

[Natural alpha-conotoxins and their synthetic analogues in studies of nicotinic acetylcholine receptors]

scientific article published on 01 March 2006

cDNA cloning, structural, and functional analyses of venom phospholipases A₂ and a Kunitz-type protease inhibitor from steppe viper Vipera ursinii renardi.

scientific article published on 23 December 2010

α-Conotoxin Analogs With Enhanced Affinity for Nicotinic Receptors and Acetylcholine-Binding Proteins

scientific article published on 01 January 2006

α-Conotoxins Enhance both the In Vivo Suppression of Ehrlich carcinoma Growth and In Vitro Reduction in Cell Viability Elicited by Cyclooxygenase and Lipoxygenase Inhibitors

scientific article published on 07 April 2020

α-conotoxins revealed different roles of nicotinic cholinergic receptor subtypes in oncogenesis of Ehrlich tumor and in the associated inflammation.

scientific article published on 3 September 2015

Paulina is supported by:

About Paulina

Help