List of works - Gracia Merino

ABCG2 transporter plays a key role in the biodistribution of melatonin and its main metabolites

Absorption and metabolism of albendazole after intestinal ischemia/reperfusion.

scientific article

Allocrite Sensing and Binding by the Breast Cancer Resistance Protein (ABCG2) and P-Glycoprotein (ABCB1).

scientific article published on 18 September 2015

An altered tissue distribution of flaxseed lignans and their metabolites in Abcg2 knockout mice.

scientific article published on 2 January 2018

Analysis of the effect of the bovine adenosine triphosphate-binding cassette transporter G2 single nucleotide polymorphism Y581S on transcellular transport of veterinary drugs using new cell culture models.

scientific article

Analysis of the interaction between tryptophan-related compounds and ATP-binding cassette transporter G2 (ABCG2) using targeted metabolomics

scientific article published on 19 November 2020

Bioavailability of albendazole sulphoxide after netobimin administration in sheep: effects of fenbendazole coadministration

scientific article published on 01 June 1999

Bioavailability of the Glucuronide and Sulfate Conjugates of Genistein and Daidzein in Breast Cancer Resistance Protein 1 Knockout Mice

scientific article published on 09 August 2011

Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk

scientific article published on 6 July 2005

Comments on Wassermann et al. (2013): Assessment of ABCG2-mediated transport of xenobiotics across the blood-milk barrier of dairy animals using a new MDCKII in vitro model

scientific article published on 31 August 2013

Differential inhibition of murine Bcrp1/Abcg2 and human BCRP/ABCG2 by the mycotoxin fumitremorgin C.

scientific article published on 22 July 2010

Effect of amphiphilic surfactant agents on the gastrointestinal absorption of albendazole in cattle

scientific article published in April 2003

Effect of bovine ABCG2 Y581S polymorphism on concentrations in milk of enrofloxacin and its active metabolite ciprofloxacin.

scientific article

Effect of bovine ABCG2 polymorphism Y581S SNP on secretion into milk of enterolactone, riboflavin and uric acid.

scientific article

Effects of ischemia–reperfusion on the absorption and esterase metabolism of diltiazem in rat intestine

scientific article published on 06 October 2006

Effects of triclabendazole on secretion of danofloxacin and moxidectin into the milk of sheep: role of triclabendazole metabolites as inhibitors of the ruminant ABCG2 transporter

scientific article published on 6 August 2013

Flaxseed-enriched diets change milk concentration of the antimicrobial danofloxacin in sheep

scientific article published on 15 January 2018

Fluoroquinolone efflux mediated by ABC transporters.

scientific article published on September 2008

Ginseng increases intestinal elimination of albendazole sulfoxide in the rat.

scientific article published in September 2003

Human breast cancer resistance protein: interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine, and transport of cimetidine.

scientific article published on 13 September 2004

Improved LC method to determine ivermectin in plasma.

scientific article published in March 2003

In vitro and in vivo interaction of moxidectin with BCRP/ABCG2.

scientific article

In vivo inhibition of BCRP/ABCG2 mediated transport of nitrofurantoin by the isoflavones genistein and daidzein: a comparative study in Bcrp1 (-/-) mice.

scientific article published on 7 July 2010

Inhibition of ABCG2/BCRP transporter by soy isoflavones genistein and daidzein: effect on plasma and milk levels of danofloxacin in sheep.

scientific article

Inhibitory effects of different antioxidants on hyaluronan depolymerization

scientific article published on 2 November 2006

Interaction of enrofloxacin with breast cancer resistance protein (BCRP/ABCG2): influence of flavonoids and role in milk secretion in sheep

scientific article published on 01 August 2006

Intestinal elimination of albendazole sulfoxide: pharmacokinetic effects of inhibitors

scientific article published in September 2003

Involvement of breast cancer resistance protein (ABCG2) in the biliary excretion mechanism of fluoroquinolones.

scientific article

Involvement of breast cancer resistance protein (BCRP/ABCG2) in the secretion of danofloxacin into milk: interaction with ivermectin.

scientific article published on 11 October 2010

Involvement of breast cancer resistance protein (BCRP1/ABCG2) in the bioavailability and tissue distribution of trans-resveratrol in knockout mice

scientific article published in April 2010

Milk secretion of nitrofurantoin, as a specific BCRP/ABCG2 substrate, in assaf sheep: modulation by isoflavones

scientific article published in October 2009

Modulation of the activity of ABC transporters (P-glycoprotein, MRP2, BCRP) by flavonoids and drug response.

scientific article published on February 2010

Multidrug transporter ABCG2/breast cancer resistance protein secretes riboflavin (vitamin B2) into milk

scientific article published on 4 December 2006

Natural allelic variants of bovine ATP-binding cassette transporter ABCG2: increased activity of the Ser581 variant and development of tools for the discovery of new ABCG2 inhibitors

scientific article published on 29 September 2008

Novel in vitro systems for prediction of veterinary drug residues in ovine milk and dairy products

scientific article published on 9 May 2014

Predicting Activators and Inhibitors of the Breast Cancer Resistance Protein (ABCG2) and P-Glycoprotein (ABCB1) Based on Mechanistic Considerations.

scientific article

Protective effects of Panax ginseng on muscle injury and inflammation after eccentric exercise

scientific article published in November 2001

Reevaluation of the roles of ABCG2 in the disposition of genistein.

scientific article published on November 2012

Role of ABC transporters in veterinary drug research and parasite resistance.

scientific article

Role of ABCG2 in transport of the mammalian lignan enterolactone and its secretion into milk in Abcg2 knockout mice.

scientific article published on 25 February 2014

Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver

scientific article

Short communication: The gain-of-function Y581S polymorphism of the ABCG2 transporter increases secretion into milk of danofloxacin at the therapeutic dose for mastitis treatment

scientific article published on 07 November 2014

Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain

scientific article

The ABC membrane transporter ABCG2 prevents access of FAAH inhibitor URB937 to the central nervous system

scientific article published on 07 July 2011

The Bovine ATP-Binding Cassette Transporter ABCG2 Tyr581Ser Single-Nucleotide Polymorphism Increases Milk Secretion of the Fluoroquinolone Danofloxacin

scientific article published on 10 December 2012

The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin.

scientific article published on 11 February 2005

The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk.

scientific article

The gut microbiota ellagic acid-derived metabolite urolithin A and its sulfate conjugate are substrates for the drug efflux transporter breast cancer resistance protein (ABCG2/BCRP).

scientific article

List of works by Gracia Merino

ABCG2 transporter plays a key role in the biodistribution of melatonin and its main metabolites

Absorption and metabolism of albendazole after intestinal ischemia/reperfusion.

Allocrite Sensing and Binding by the Breast Cancer Resistance Protein (ABCG2) and P-Glycoprotein (ABCB1).

An altered tissue distribution of flaxseed lignans and their metabolites in Abcg2 knockout mice.

Analysis of the effect of the bovine adenosine triphosphate-binding cassette transporter G2 single nucleotide polymorphism Y581S on transcellular transport of veterinary drugs using new cell culture models.

Analysis of the interaction between tryptophan-related compounds and ATP-binding cassette transporter G2 (ABCG2) using targeted metabolomics

Bioavailability of albendazole sulphoxide after netobimin administration in sheep: effects of fenbendazole coadministration

Bioavailability of the Glucuronide and Sulfate Conjugates of Genistein and Daidzein in Breast Cancer Resistance Protein 1 Knockout Mice

Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk

Comments on Wassermann et al. (2013): Assessment of ABCG2-mediated transport of xenobiotics across the blood-milk barrier of dairy animals using a new MDCKII in vitro model

Differential inhibition of murine Bcrp1/Abcg2 and human BCRP/ABCG2 by the mycotoxin fumitremorgin C.

Effect of amphiphilic surfactant agents on the gastrointestinal absorption of albendazole in cattle

Effect of bovine ABCG2 Y581S polymorphism on concentrations in milk of enrofloxacin and its active metabolite ciprofloxacin.

Effect of bovine ABCG2 polymorphism Y581S SNP on secretion into milk of enterolactone, riboflavin and uric acid.

Effects of ischemia–reperfusion on the absorption and esterase metabolism of diltiazem in rat intestine

Effects of triclabendazole on secretion of danofloxacin and moxidectin into the milk of sheep: role of triclabendazole metabolites as inhibitors of the ruminant ABCG2 transporter

Flaxseed-enriched diets change milk concentration of the antimicrobial danofloxacin in sheep

Fluoroquinolone efflux mediated by ABC transporters.

Ginseng increases intestinal elimination of albendazole sulfoxide in the rat.

Human breast cancer resistance protein: interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine, and transport of cimetidine.

Improved LC method to determine ivermectin in plasma.

In vitro and in vivo interaction of moxidectin with BCRP/ABCG2.

In vivo inhibition of BCRP/ABCG2 mediated transport of nitrofurantoin by the isoflavones genistein and daidzein: a comparative study in Bcrp1 (-/-) mice.

Inhibition of ABCG2/BCRP transporter by soy isoflavones genistein and daidzein: effect on plasma and milk levels of danofloxacin in sheep.

Inhibitory effects of different antioxidants on hyaluronan depolymerization

Interaction of enrofloxacin with breast cancer resistance protein (BCRP/ABCG2): influence of flavonoids and role in milk secretion in sheep

Intestinal elimination of albendazole sulfoxide: pharmacokinetic effects of inhibitors

Involvement of breast cancer resistance protein (ABCG2) in the biliary excretion mechanism of fluoroquinolones.

Involvement of breast cancer resistance protein (BCRP/ABCG2) in the secretion of danofloxacin into milk: interaction with ivermectin.

Involvement of breast cancer resistance protein (BCRP1/ABCG2) in the bioavailability and tissue distribution of trans-resveratrol in knockout mice

Milk secretion of nitrofurantoin, as a specific BCRP/ABCG2 substrate, in assaf sheep: modulation by isoflavones

Modulation of the activity of ABC transporters (P-glycoprotein, MRP2, BCRP) by flavonoids and drug response.

Multidrug transporter ABCG2/breast cancer resistance protein secretes riboflavin (vitamin B2) into milk

Natural allelic variants of bovine ATP-binding cassette transporter ABCG2: increased activity of the Ser581 variant and development of tools for the discovery of new ABCG2 inhibitors

Novel in vitro systems for prediction of veterinary drug residues in ovine milk and dairy products

Predicting Activators and Inhibitors of the Breast Cancer Resistance Protein (ABCG2) and P-Glycoprotein (ABCB1) Based on Mechanistic Considerations.

Protective effects of Panax ginseng on muscle injury and inflammation after eccentric exercise

Reevaluation of the roles of ABCG2 in the disposition of genistein.

Role of ABC transporters in veterinary drug research and parasite resistance.

Role of ABCG2 in transport of the mammalian lignan enterolactone and its secretion into milk in Abcg2 knockout mice.

Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver

Short communication: The gain-of-function Y581S polymorphism of the ABCG2 transporter increases secretion into milk of danofloxacin at the therapeutic dose for mastitis treatment

Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain

The ABC membrane transporter ABCG2 prevents access of FAAH inhibitor URB937 to the central nervous system

The Bovine ATP-Binding Cassette Transporter ABCG2 Tyr581Ser Single-Nucleotide Polymorphism Increases Milk Secretion of the Fluoroquinolone Danofloxacin

The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin.

The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk.

The gut microbiota ellagic acid-derived metabolite urolithin A and its sulfate conjugate are substrates for the drug efflux transporter breast cancer resistance protein (ABCG2/BCRP).