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List of works by Michael W. Lutz

A Genetics-based Biomarker Risk Algorithm for Predicting Risk of Alzheimer's Disease.

scientific article published on January 2016

A cytosine-thymine (CT)-rich haplotype in intron 4 of SNCA confers risk for Lewy body pathology in Alzheimer's disease and affects SNCA expression.

scientific article

A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing.

scientific article published on 4 December 2012

A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging

scientific article

A mathematical model for analysis of pharmacologically induced changes in the kinetics of cardiac muscle

scientific article published in November 1996

APOE ε4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans

scientific article

APOE/TOMM40 genetic loci, white matter hyperintensities, and cerebral microbleeds

scientific article published on 26 August 2015

African-American TOMM40'523-APOE haplotypes are admixture of West African and Caucasian alleles.

scientific article published on 26 September 2014

Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936.

scientific article published on 08 January 2014

Alzheimer's disease susceptibility genes APOE and TOMM40, and hippocampal volumes in the Lothian birth cohort 1936.

scientific article

Alzheimer’s disease: diagnostics, prognostics and the road to prevention ⬇️

scientific article published on June 29, 2010

Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation, and plasma lipids in the Health and Retirement Study

scientific article published on 06 March 2019

Are APOE ɛ genotype and TOMM40 poly-T repeat length associations with cognitive ageing mediated by brain white matter tract integrity?

scientific article

Assessment of the COBAS Amplicor HBV Monitor Test for quantitation of serum hepatitis B virus DNA levels.

scientific article published on June 2002

Cerebrospinal fluid cortisol concentrations in healthy elderly are affected by both APOE and TOMM40 variants

scientific article published on 30 July 2011

Characterization of APOE and TOMM40 allele frequencies in the Japanese population

scientific article published on 6 September 2017

Characterization of the poly-T variant in the TOMM40 gene in diverse populations

scientific article (publication date: 2012)

Correction: Effect of APOE and CD33 on Cognitive Decline

scientific article published on 31 July 2015

Drug and tissue factors both confound KA measurements

scientific article published on 01 July 1990

Effect of APOE and CD33 on Cognitive Decline

scientific article published on 23 June 2015

Family history and TOMM40 '523 interactive associations with memory in middle-aged and Alzheimer's disease cohorts

scientific article published on 10 May 2017

Genetic analysis of α-synuclein 3' untranslated region and its corresponding microRNAs in relation to Parkinson's disease compared to dementia with Lewy bodies

scientific article published on 18 April 2017

Genetic variation at a single locus and age of onset for Alzheimer's disease.

scientific article

Interaction Between the FOXO1A-209 Genotype and Tea Drinking Is Significantly Associated with Reduced Mortality at Advanced Ages

scientific article published on 28 September 2015

Interactions of 1263W94 with other antiviral agents in inhibition of human cytomegalovirus replication.

scientific article

KRAX is important operational determinant of tissue response. KRAX as parameter for classification

scientific article published on 01 October 1988

Levels of cerebrospinal fluid neurofilament light protein in healthy elderly vary as a function of TOMM40 variants

scientific article

Managing genomic and proteomic knowledge

scientific article published on January 2005

Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline

scientific article published on 15 June 2017

New Genetic Approaches to AD: Lessons from APOE-TOMM40 Phylogenetics

scientific article published on May 2016

New applications of disease genetics and pharmacogenetics to drug development.

scientific article published on 03 January 2014

Novel loci and pathways significantly associated with longevity

scientific article published on 25 February 2016

On the importance of the "antagonist assumption" to how receptors express themselves.

scientific article

Peak alignment of urine NMR spectra using fuzzy warping

scientific article published in March 2006

Quantitation of hepatitis B viremia and emergence of YMDD variants in patients with chronic hepatitis B treated with lamivudine

scientific article published on 01 December 1999

Shared genetic etiology underlying late-onset Alzheimer's disease and posttraumatic stress syndrome

scientific article published on 26 June 2020

Structural variants can be more informative for disease diagnostics, prognostics and translation than current SNP mapping and exon sequencing

scientific article published on 04 January 2016

TOMM40 and APOE: Requirements for replication studies of association with age of disease onset and enrichment of a clinical trial.

scientific article published on 18 January 2013

TOMM40'523 variant and cognitive decline in older persons with APOE ε3/3 genotype

scientific article published on 20 January 2017

The Alu neurodegeneration hypothesis: A primate-specific mechanism for neuronal transcription noise, mitochondrial dysfunction, and manifestation of neurodegenerative disease.

scientific article

The SSV Evaluation System: A Tool to Prioritize Short Structural Variants for Studies of Possible Regulatory and Causal Variants

scientific article published on 9 June 2016

The TOMM40 poly-T rs10524523 variant is associated with cognitive performance among non-demented elderly with type 2 diabetes

scientific article published on 13 June 2014

The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes

scientific article

The cubic ternary complex receptor-occupancy model. III. resurrecting efficacy

scientific article published in August 1996

The effect of TOMM40 poly‐T length on gray matter volume and cognition in middle‐aged persons with APOEɛ3/ɛ3 genotype ⬇️

scientific article published on July 1, 2011

The genetic contributions of SNCA and LRRK2 genes to Lewy Body pathology in Alzheimer's disease

scientific article

The importance of being connected

scientific article published in January 2011

Translocase of Outer Mitochondrial Membrane 40 Homolog (TOMM40) Poly-T Length Modulates Lorazepam-Related Cognitive Toxicity in Healthy APOE ϵ4-Negative Elderly

article

Understanding the genetics of APOE and TOMM40 and role of mitochondrial structure and function in clinical pharmacology of Alzheimer's disease.

scientific article published on 3 May 2016

Use of resampling techniques to estimate the variance of parameters in pharmacological assays when experimental protocols preclude independent replication: an example using Schild regressions

scientific article published in September 1995

Using genetics to enable studies on the prevention of Alzheimer's disease

scientific article

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