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List of works by Karin Borges

A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy models

scientific article published on 11 February 2015

A pilot study of add-on oral triheptanoin treatment for children with medically refractory epilepsy

scientific article published on 07 August 2018

ACTH and PMX53 recover synaptic transcriptome alterations in a rat model of infantile spasms.

scientific article

Adult rat optic nerve oligodendrocyte progenitor cells express a distinct repertoire of voltage- and ligand-gated ion channels

scientific article published on 01 April 1995

Alterations in Cytosolic and Mitochondrial [U-13C]Glucose Metabolism in a Chronic Epilepsy Mouse Model.

scientific article

Alterations of hippocampal glucose metabolism by even versus uneven medium chain triglycerides.

scientific article published on 30 October 2013

Alternative Fuels in Epilepsy and Amyotrophic Lateral Sclerosis.

scientific article published on 21 November 2016

Ampa/kainate receptor activation in murine oligodendrocyte precursor cells leads to activation of a cation conductance, calcium influx and blockade of delayed rectifying K+ channels

scientific article published on 01 November 1994

Anticonvulsant effects of a triheptanoin diet in two mouse chronic seizure models

scientific article published on August 4, 2010

Anticonvulsant profile of a balanced ketogenic diet in acute mouse seizure models

scientific article published on 18 June 2008

Anticonvulsant screening of luteolin in four mouse seizure models.

scientific article published on 9 July 2013

Blockade of K+ channels induced by AMPA/kainate receptor activation in mouse oligodendrocyte precursor cells is mediated by NA+ entry

scientific article published on 01 November 1995

Brain mitochondrial metabolic dysfunction and glutamate level reduction in the pilocarpine model of temporal lobe epilepsy in mice

scientific article published on 24 April 2013

Chronic acetyl-L-carnitine alters brain energy metabolism and increases noradrenaline and serotonin content in healthy mice

scientific article

Complex alterations in microglial M1/M2 markers during the development of epilepsy in two mouse models

scientific article published on 3 April 2015

Degeneration and proliferation of astrocytes in the mouse dentate gyrus after pilocarpine-induced status epilepticus

scientific article

Diffusion MRI unveils the spatiotemporal microstructural grey matter changes following injury in the rodent brain

scientific article published on 20 December 2018

Eicosapentaenoic and docosahexaenoic acids are not anticonvulsant or neuroprotective in acute mouse seizure models

scientific article published on 14 July 2008

Formulation of spray-dried phenytoin loaded poly(epsilon-caprolactone) microcarrier intended for brain delivery to treat epilepsy.

scientific article

Functional organization of the GluR1 glutamate receptor promoter.

scientific article

Gene expression changes after seizure preconditioning in the three major hippocampal cell layers

scientific article

Heptanoate is neuroprotective in vitro but triheptanoin post-treatment did not protect against middle cerebral artery occlusion in rats

scientific article published on 01 August 2018

Impaired Pentose Phosphate Pathway in the Spinal Cord of the hSOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis

scientific article published on 26 January 2019

Impairments in Oxidative Glucose Metabolism in Epilepsy and Metabolic Treatments Thereof

scientific article published on 31 August 2018

Metabolic Dysfunctions in Amyotrophic Lateral Sclerosis Pathogenesis and Potential Metabolic Treatments

scientific article published on January 2016

Modification of Astrocyte Metabolism as an Approach to the Treatment of Epilepsy: Triheptanoin and Acetyl-L-Carnitine

scientific article published on 03 October 2015

Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model.

scientific article

Neuronal glucose metabolism is impaired while astrocytic TCA cycling is unaffected at symptomatic stages in the hSOD1G93A mouse model of amyotrophic lateral sclerosis

scientific article published on 19 March 2018

Open-label long-term treatment of add-on triheptanoin in adults with drug-resistant epilepsy

scientific article published on 12 April 2020

Prenatal betamethasone exposure increases corticotropin-releasing hormone expression along with increased hippocampal slice excitability in the developing hippocampus

scientific article published on 15 January 2020

Protective effect of the ketogenic diet in Scn1a mutant mice

scientific article published on 29 July 2011

Quantitative transcriptional neuroanatomy of the rat hippocampus: evidence for wide-ranging, pathway-specific heterogeneity among three principal cell layers

scientific article

Randomised trial of add‐on triheptanoin vs. medium chain triglycerides in adults with refractory epilepsy

scientific article published on 22 February 2019

Reciprocal changes of CD44 and GAP-43 expression in the dentate gyrus inner molecular layer after status epilepticus in mice

scientific article

Slc10A4 - what do we know about the function of this "secret ligand carrier" protein?

scientific article published on 27 June 2013

Sulforaphane Protects against High Cholesterol-Induced Mitochondrial Bioenergetics Impairments, Inflammation, and Oxidative Stress and Preserves Pancreatic β-Cells Function

scientific article published on 12 March 2017

Sulforaphane is anticonvulsant and improves mitochondrial function

scientific article published on 14 September 2015

The deleterious effect of cholesterol and protection by quercetin on mitochondrial bioenergetics of pancreatic β-cells, glycemic control and inflammation: In vitro and in vivo studies

scientific article published on 26 August 2016

The effects of C5aR1 on leukocyte infiltration following pilocarpine-induced status epilepticus.

scientific article

The ketogenic diet changes metabolite levels in hippocampal extracellular fluid

scientific article published on 9 November 2010

Tridecanoin is anticonvulsant, antioxidant, and improves mitochondrial function.

scientific article

Triheptanoin Protects Motor Neurons and Delays the Onset of Motor Symptoms in a Mouse Model of Amyotrophic Lateral Sclerosis

scientific article

Triheptanoin alters [U-13C6]-glucose incorporation into glycolytic intermediates and increases TCA cycling by normalizing the activities of pyruvate dehydrogenase and oxoglutarate dehydrogenase in a chronic epilepsy mouse model

scientific article published on 19 March 2019

Triheptanoin in acute mouse seizure models

scientific article published on 20 January 2012

Triheptanoin partially restores levels of tricarboxylic acid cycle intermediates in the mouse pilocarpine model of epilepsy

scientific article published on 2 December 2013

Triheptanoin protects against status epilepticus-induced hippocampal mitochondrial dysfunctions, oxidative stress and neuronal degeneration

scientific article

Triheptanoin reduces seizure susceptibility in a syndrome-specific mouse model of generalized epilepsy.

scientific article

Triheptanoin—A medium chain triglyceride with odd chain fatty acids: A new anaplerotic anticonvulsant treatment?

scientific article published on August 19, 2011