Search filters

List of works by Alison Simmons

A practical solution for preserving single cells for RNA sequencing

scientific article published in February 2018

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

scientific article published on 09 August 2016

Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication

article

An integrative analysis of gene expression and molecular interaction data to identify dys-regulated sub-networks in inflammatory bowel disease.

scientific article

Ataxin-3 Links NOD2 and TLR2 Mediated Innate Immune Sensing and Metabolism in Myeloid Cells

scientific article published on 19 July 2019

Becalming Type 17 Inflammation in Ulcerative Colitis

scientific article published on 01 April 2019

Benzimidazoles Promote Anti-TNF Mediated Induction of Regulatory Macrophages and Enhance Therapeutic Efficacy in a Murine Model

scientific article published on 16 August 2017

CD90(+) Stromal Cells are Non-Professional Innate Immune Effectors of the Human Colonic Mucosa

scientific article published on 30 September 2013

Cannabis, Cannabinoids, and the Endocannabinoid System-Is there Therapeutic Potential for Inflammatory Bowel Disease?

scientific article published on 01 March 2019

Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses

article

Colonic epithelial cell diversity in health and inflammatory bowel disease

scientific article published on 27 February 2019

Corrigendum: CD90(+) Stromal Cells are Non-Professional Innate Immune Effectors of the Human Colonic Mucosa

scientific article published on 24 June 2015

Dual RNA sequencing reveals dendritic cell reprogramming in response to typhoidal Salmonella invasion

scientific article published on 04 February 2022

Elevation of intact and proteolytic fragments of acute phase proteins constitutes the earliest systemic antiviral response in HIV-1 infection

scientific article

Emerging Mechanisms of Innate Immunity and Their Translational Potential in Inflammatory Bowel Disease.

scientific article

Enriched HLA-E and CD94/NKG2A Interaction Limits Antitumor CD8+ Tumor-Infiltrating T Lymphocyte Responses

scientific article published on 18 June 2019

Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease

scientific article published on 11 August 2020

Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7.

scientific article published on 9 January 2017

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

scientific article

Functional consequences of mutations in the autophagy genes in the pathogenesis of Crohn's disease.

scientific article published on 09 August 2011

Genes, viruses and microbes

scientific article published in Nature

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.

scientific article published on 9 January 2017

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

HLA-dependent variation in SARS-CoV-2 CD8 <sup>+</sup> T cell cross-reactivity with human coronaviruses

scientific article published on 07 March 2022

Homologous and heterologous re-challenge with Salmonella Typhi and Salmonella Paratyphi A in a randomised controlled human infection model

scientific article published on 20 October 2020

ICG-001 affects DRP1 activity and ER stress correlative with its anti-proliferative effect.

scientific article published in November 2017

Immunotherapy-related hepatitis: real-world experience from a tertiary centre

scientific article published on 22 March 2019

Innate immune receptors for cross-presentation: The expanding role of NLRs.

scientific article published on 29 November 2017

Interferon-Gamma-Producing CD8<sup>+</sup> Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor-Colitis

scientific article published on 17 June 2021

Intestinal stromal cells in mucosal immunity and homeostasis.

scientific article published on 12 December 2012

Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein.

scientific article published on 4 December 2017

Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets

scientific article published in Nature Communications

Microbiome, pattern recognition receptor function in health and inflammation

article

Multi-Modal Characterization of Monocytes in Idiopathic Pulmonary Fibrosis Reveals a Primed Type I Interferon Immune Phenotype

scientific article published on 05 March 2021

NOD2 and TLR2 Signal via TBK1 and PI31 to Direct Cross-Presentation and CD8 T Cell Responses

article

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

scientific article (publication date: 2010)

NOD2-mediated autophagy and Crohn disease

scientific article published on 3 April 2010

Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virus

scientific article published on 8 October 2015

Phase I clinical trial safety of DNA- and modified virus Ankara-vectored human immunodeficiency virus type 1 (HIV-1) vaccines administered alone and in a prime-boost regime to healthy HIV-1-uninfected volunteers

scientific article

Plasma Nuclear Magnetic Resonance Metabolomics Discriminates Between High and Low Endoscopic Activity and Predicts Progression in a Prospective Cohort of Patients With Ulcerative Colitis

scientific article published on 01 November 2018

Prioritisation and network analysis of Crohn's disease susceptibility genes

scientific article

R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon

scientific article published on 25 September 2019

RNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events

scientific article

Resistance of dynamin-related protein 1 oligomers to disassembly impairs mitophagy, resulting in myocardial inflammation and heart failure

scientific article published on December 2016

Single-Cell and Time-Resolved Profiling of Intracellular Salmonella Metabolism in Primary Human Cells

scientific article published on 31 May 2019

Single-cell atlas of colonic CD8+ T cells in ulcerative colitis

scientific article published on 03 August 2020

Snapin promotes HIV-1 transmission from dendritic cells by dampening TLR8 signaling

scientific article published on 18 September 2017

Spatiotemporal analysis of human intestinal development at single-cell resolution

scientific article published on 04 January 2021

Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease

scientific article published on 27 September 2018

The Impact of Vaccination and Prior Exposure on Stool Shedding of Salmonella Typhi and Salmonella Paratyphi in 6 Controlled Human Infection Studies

scientific article published on 01 April 2019

The antiviral efficacy of HIV-specific CD8⁺ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate

scientific article

The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release.

scientific article published in September 2013

Paulina is supported by:

About Paulina

Help