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List of works by Kevin A. Roth

4-Hydroxytamoxifen Induces Autophagic Death through K-Ras Degradation ⬇️

scientific article published on May 30, 2013

A beautiful science

scientific article published on October 2006

A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death

scientific article

Acromegaly and pheochromocytoma: a multiple endocrine syndrome caused by a plurihormonal adrenal medullary tumor

scientific article published in December 1986

Acute and chronic stress effects on open field activity in the rat: implications for a model of depression

scientific article published on 01 January 1981

Acute neonatal glucocorticoid exposure produces selective and rapid cerebellar neural progenitor cell apoptotic death

scientific article

Adrenergic control of motor activity: effects of PNMT inhibition upon open field behavior in the rat.

scientific article published in October 1978

Advances in Experimental Neuropathology: New Methods and Insights

scientific article published on 20 January 2016

Aging and energetics' 'Top 40' future research opportunities 2010-2013.

scientific article

Amphetamine and tranylcypromine in an animal model of depression: pharmacological specificity of the reversal effect

scientific article published in January 1981

Apaf1-dependent programmed cell death is required for inner ear morphogenesis and growth

scientific article published in May 2004

Apoptosis and brain development.

scientific article

Appetitive determinants of self-stimulation

scientific article

Autophagy in Brain Tumors: A New Target for Therapeutic Intervention ⬇️

scientific article published on January 1, 2012

BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediate neural precursor cell death.

scientific article published in July 2006

BNIP3 regulates AT101 [(-)-gossypol] induced death in malignant peripheral nerve sheath tumor cells.

scientific article

Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease.

scientific article

Bcl-2 family and the central nervous system: from rheostat to real complex

scientific article

Bcl-2 family regulation of neuronal development and neurodegeneration.

scientific article published on March 2004

Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage

scientific article published in October 2002

Bid regulation of neuronal apoptosis

scientific article published in June 2001

Blockade of glutamate mGlu5 receptors in a rat model of neuropathic pain prevents early over-expression of pro-apoptotic genes and morphological changes in dorsal horn lamina II.

scientific article published in March 2004

CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress

scientific article

Caspase regulation of genotoxin-induced neural precursor cell death

scientific article published in November 2003

Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis.

scientific article published in February 2007

Central and peripheral contributions to hypothalamic epinephrine

scientific article published in November 1981

Central elevation of phenylethanolamine N-methyltransferase activity following stress

scientific article

Central epinergic inhibition of corticosterone release in rat

scientific article published on 01 May 1981

Changes in rat hypothalamic and brain stem catecholamine concentrations following acute administration of phenylethanolamine-N-methyltransferase inhibitors

scientific article published on 01 October 1980

Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent

scientific article published on 27 January 2010

Cholera toxin binds to differentiating neurons in the developing murine basal ganglia

scientific article

Colocalization of alpha-neo-endorphin and dynorphin immunoreactivity in hypothalamic neurons

scientific article published in December 1981

Coming into focus: computational pathology as the new big data microscope

scientific article published on 01 March 2015

Correction: BNIP3 Regulates AT101 [(-)-Gossypol] Induced Death in Malignant Peripheral Nerve Sheath Tumor Cells

scientific article published on 27 August 2015

Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.

scientific article published on September 1996

Cytoplasmic p53 and activated Bax regulate p53-dependent, transcription-independent neural precursor cell apoptosis.

scientific article

Deafferentation-induced abnormal neurofilament phosphorylation in red nucleus neurones

scientific article published in December 2001

Deficiency of Pro-apoptotic Hrk Attenuates Programmed Cell Death in the Developing Murine Nervous System but Does Not Affect Bcl-x Deficiency-Induced Neuron Apoptosis ⬇️

scientific article published on November 1, 2011

Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy.

scientific article published in February 2008

Developmentally-regulated lectin binding in the embryonic mouse telencephalon.

scientific article published on April 1995

Differential susceptibility of prevertebral and paravertebral sympathetic ganglia to experimental injury

scientific article published on 01 September 1988

Distribution of gastrin releasing peptide--bombesin-like immunostaining in rat brain

scientific article

Effect of streptozotocin-induced diabetes on NGF, P75(NTR) and TrkA content of prevertebral and paravertebral rat sympathetic ganglia

scientific article published on 01 June 2000

Effects of chronic experimental streptozotocin-induced diabetes on the noradrenergic and peptidergic innervation of the rat alimentary tract

scientific article published on 01 August 1988

Enx (Hox11L1)-deficient mice develop myenteric neuronal hyperplasia and megacolon

scientific article published in June 1997

Epinephrine accumulation in rat brain after chronic administration of pargyline and LY 51641--comparison with other brain amines

scientific article published in July 1985

Epinephrine, norepinephrine, dopamine and serotonin: differential effects of acute and chronic stress on regional brain amines

scientific article published in May 1982

Ethanol-induced caspase-3 activation in the in vivo developing mouse brain

scientific article published in March 2002

Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain ⬇️

scientific article published on October 1, 2003

Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy

scientific article published on 19 June 2005

Further studies on a novel animal model of depression: therapeutic effects of a tricyclic antidepressant

scientific article published in January 1981

Gamma-secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney

scientific journal article

Hypothalamic catecholamine changes under acute stress occur independently of nicotinic stimulation.

scientific article published in January 1982

Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: protection by mood stabilizers and imipramine

scientific article published in February 2005

Identification of gastrin releasing peptide-related substances in guinea pig and rat brain

scientific article published in April 1983

Immunohistochemical detection with quantum dots.

scientific article published in January 2007

Immunohistochemical localization of GAP-43 in rat and human sympathetic nervous system--effects of aging and diabetes

scientific article published in June 1991

Immunohistochemical localization of dynorphin (1-8) in hypothalamic magnocellular neurons: evidence for absence of proenkephalin

scientific article

Immunohistochemical studies indicate multiple enteroendocrine cell differentiation pathways in the mouse proximal small intestine

scientific article published on 01 September 1994

Immunoreactive corticotropin releasing factor (CRF) and vasopressin are colocalized in a subpopulation of the immunoreactive vasopressin cells in the paraventricular nucleus of the hypothalamus

scientific article

Immunoreactive dynorphin-(1-8) and corticotropin- releasing factor in subpopulation of hypothalamic neurons

scientific article published on 01 January 1983

In vivo intraneuronal MAO inhibition in rat brain SKF 64139, comparison to other potent PNMT inhibitors

scientific article published on 01 March 1981

Interaction of stress and morphine in the rat using a classical conditioning design

scientific article published in March 1980

Intracranial ependymoma long term outcome, patterns of failure.

scientific article

Isolation and characterization of beta-endorphin-(1-9) from human and rat pituitaries

scientific article

Isolation and characterization of substance P, substance P 5-11, and substance K from two metastatic ileal carcinoids.

scientific article published in November 1985

Journal of Histochemistry and Cytochemistry editorial policies and ethical guidelines

scientific article published on 01 February 2006

Kainic acid induces early and transient autophagic stress in mouse hippocampus

scientific article published on 27 December 2006

Labeled lines in the retinotectal system: markers for retinorecipient sublaminae and the retinal ganglion cell subsets that innervate them

scientific article published on 15 September 2006

Localization of electrogenic Na/bicarbonate cotransporter NBCe1 variants in rat brain

scientific article published on 05 June 2008

Loss of BH3-only protein Bim inhibits apoptosis of hemopoietic cells in the fetal liver and male germ cells but not neuronal cells in bcl-x-deficient mice

scientific article published on 7 July 2008

Low-dose bafilomycin attenuates neuronal cell death associated with autophagy-lysosome pathway dysfunction.

scientific article

Lysosome dysfunction triggers Atg7-dependent neural apoptosis

scientific article

Malignant peripheral nerve sheath tumor invasion requires aberrantly expressed EGF receptors and is variably enhanced by multiple EGF family ligands.

scientific article published on March 2013

Methionine-enkephalin and thyrotropin-stimulating hormone are intimately related in the human anterior pituitary

scientific article published in April 1988

Molar tooth development in caspase-3 deficient mice.

scientific article published in January 2006

Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: a new model for virus-induced vascular disease.

scientific article published in December 1997

N-terminally deleted forms of the prion protein activate both Bax-dependent and Bax-independent neurotoxic pathways.

scientific article

Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125.

scientific article published on January 2007

Neural precursor cell apoptosis and glial tumorigenesis following transplacental ethyl-nitrosourea exposure

scientific article published in December 2001

Neural precursor cells are protected from apoptosis induced by trophic factor withdrawal or genotoxic stress by inhibitors of glycogen synthase kinase 3.

scientific article

Neural precursor cells possess multiple p53-dependent apoptotic pathways

scientific article published on 3 March 2006

Neuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis.

scientific article published on April 2014

Neurokinin B- and substance P-like immunoreactivity are co-localized in enteric nerves of rat ileum

scientific article published on 01 March 1999

Neurotrophin-4 selectively promotes survival of striatal neurons in organotypic slice culture

scientific article

Open Field Behavior after Chronic Self Stimulation ⬇️

scientific article published on January 1, 1979

Our Journal, Our History, Our Cytophilia

scientific article published in 2008

Oxidative stress and autophagy in the regulation of lysosome-dependent neuron death.

scientific article

Pancreastatin distribution and plasma levels in the pig.

scientific article

Polyglutamine disease and neuronal cell death.

scientific article

Prion protein protects against ethanol-induced Bax-mediated cell death in vivo

scientific article

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

scientific article

Protector turns predator: Autophagic death via selective degradation of KRAS.

scientific article

Publish and perish: the future fate of not-for-profit society-sponsored journals?

scientific article published on 01 October 2007

Reduced behavioral activity due to opiate blockade: relations to stress

scientific article published on 01 January 1981

Regulated targeting of BAX to mitochondria.

scientific article

Regulation of mouse brain glycogen synthase kinase-3 by atypical antipsychotics.

scientific article published on 4 May 2006

Rnx deficiency results in congenital central hypoventilation

scientific journal article

Role of caspase-3 in ethanol-induced developmental neurodegeneration

scientific article published on 31 May 2005

Role of reactive oxygen species and spinal cord apoptotic genes in the development of neuropathic pain

scientific article published on 01 December 2006

Rotenone inhibits autophagic flux prior to inducing cell death.

scientific article

Science isn't science if it isn't reproducible

scientific article published on 01 January 2015

Selective involvement of BH3-only Bcl-2 family members Bim and Bad in neonatal hypoxia-ischemia

scientific article published on 15 June 2006

Spatial differentiation of the intestinal epithelium: analysis of enteroendocrine cells containing immunoreactive serotonin, secretin, and substance P in normal and transgenic mice ⬇️

scientific article published on August 1, 1990

Stress induced grooming in the rat--an endorphin mediated syndrome

scientific article published on 01 July 1979

Stress, behavioral arousal, and open field activity--a reexamination of emotionality in the rat.

scientific article published in January 1979

Substance P is distributed between somatotrophs and thyrotrophs in a sexually dimorphic manner in rat.

scientific article published in January 1991

Substance-P is present in a subset of thyrotrophs in the human pituitary

scientific article

Tail pinch facilitation of self-stimulation in the rat--dependence upon dopamine and independence of opiates

scientific article published in March 1980

Tail pinch induced stress-arousal facilitates brain stimulation reward

scientific article

Tamoxifen Induces Cytotoxic Autophagy in Glioblastoma.

scientific article published on 11 August 2016

Temporal differentiation and migration of substance P, serotonin, and secretin immunoreactive enteroendocrine cells in the mouse proximal small intestine

scientific article published in August 1992

The American Journal of Pathology Centennial Project: celebrating 100 years of the American Society for Investigative Pathology

scientific article published on 29 February 2012

The American Journal of Pathology Centennial Project: the centennial celebration is over, but the science moves forward

scientific article

The American Journal of Pathology, Value Beyond Simple Metrics

scientific article

The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy.

scientific article published on January 2008

The pan erbB inhibitor PD168393 enhances lysosomal dysfunction-induced apoptotic death in malignant peripheral nerve sheath tumor cells

scientific article published on 18 January 2012

The proapoptotic BH3-only, Bcl-2 family member, Puma is critical for acute ethanol-induced neuronal apoptosis

scientific article published on July 2009

Tissue transglutaminase overexpression in the brain potentiates calcium-induced hippocampal damage

scientific article published on 15 March 2006

Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14

scientific article

Understanding Lung Development, Injury, and Repair

scientific article published on 22 August 2016

Usp9X Regulates Cell Death in Malignant Peripheral Nerve Sheath Tumors

scientific article published in Scientific Reports

bcl-2/Adenovirus E1B 19-kd interacting protein 3 (BNIP3) regulates hypoxia-induced neural precursor cell death

scientific article published on December 2009

p53 deficiency fails to prevent increased programmed cell death in the Bcl-X(L)-deficient nervous system

scientific article published in October 2002

p53 transcription-dependent and -independent regulation of cerebellar neural precursor cell apoptosis

scientific article published in January 2007

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