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List of works by Yun Chen

Ach1 is involved in shuttling mitochondrial acetyl units for cytosolic C2 provision in Saccharomyces cerevisiae lacking pyruvate decarboxylase

scientific article published on 6 April 2015

Adaptive laboratory evolution of tolerance to dicarboxylic acids in Saccharomyces cerevisiae

scientific article published on 21 September 2019

Adaptive mutations in sugar metabolism restore growth on glucose in a pyruvate decarboxylase negative yeast strain

scientific article published on 8 August 2015

Advances in metabolic pathway and strain engineering paving the way for sustainable production of chemical building blocks ⬇️

scientific article published on March 28, 2013

Biobased organic acids production by metabolically engineered microorganisms

scientific article

Biofuels. Altered sterol composition renders yeast thermotolerant

scientific article

Comparison of the metabolic response to over-production of p-coumaric acid in two yeast strains.

scientific article published on 31 October 2017

Coupled incremental precursor and co-factor supply improves 3-hydroxypropionic acid production in Saccharomyces cerevisiae

scientific article

De novo biosynthesis of bioactive isoflavonoids by engineered yeast cell factories

scientific article published on 19 October 2021

De novo production of protoberberine and benzophenanthridine alkaloids through metabolic engineering of yeast

scientific article published on 9 October 2024

De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae

scientific article

Diversion of flux toward sesquiterpene production in Saccharomyces cerevisiae by fusion of host and heterologous enzymes

scientific article

Dynamic control of gene expression in Saccharomyces cerevisiae engineered for the production of plant sesquitepene α-santalene in a fed-batch mode

scientific article published on 08 February 2012

Effects of acetoacetyl-CoA synthase expression on production of farnesene in Saccharomyces cerevisiae

scientific article published on 9 February 2017

Effects of overexpression of STB5 in Saccharomyces cerevisiae on fatty acid biosynthesis, physiology and transcriptome

scientific article published on 01 May 2019

Elimination of the last reactions in ergosterol biosynthesis alters the resistance of Saccharomyces cerevisiae to multiple stresses

scientific article

Elucidating aromatic acid tolerance at low pH in Saccharomyces cerevisiae using adaptive laboratory evolution

scientific article published on 26 October 2020

Enabling technologies to advance microbial isoprenoid production

scientific article published on January 2015

Engineering and systems-level analysis of Saccharomyces cerevisiae for production of 3-hydroxypropionic acid via malonyl-CoA reductase-dependent pathway

scientific article

Engineering of acetyl-CoA metabolism for the improved production of polyhydroxybutyrate in Saccharomyces cerevisiae

scientific article published on 25 September 2012

Enhancing the copy number of episomal plasmids in Saccharomyces cerevisiae for improved protein production

scientific article published on 25 April 2012

Establishing a platform cell factory through engineering of yeast acetyl-CoA metabolism

scientific article published on 17 November 2012

Expanding the Dynamic Range of a Transcription Factor-Based Biosensor in Saccharomyces cerevisiae

scientific article published on 09 August 2019

From flavors and pharmaceuticals to advanced biofuels: production of isoprenoids in Saccharomyces cerevisiae

scientific article

Functional expression and evaluation of heterologous phosphoketolases in Saccharomyces cerevisiae

scientific article published on 15 November 2016

Functional pyruvate formate lyase pathway expressed with two different electron donors in Saccharomyces cerevisiae at aerobic growth

scientific article

Genetic modulation of the overexpression of tailoring genes eryK and eryG leading to the improvement of erythromycin A purity and production in Saccharopolyspora erythraea fermentation

scientific article

Global rewiring of cellular metabolism renders Saccharomyces cerevisiae Crabtree negative

scientific article published in Nature Communications

Harnessing xylose pathways for biofuels production

article

Heterologous phosphoketolase expression redirects flux towards acetate, perturbs sugar phosphate pools and increases respiratory demand in Saccharomyces cerevisiae

scientific article published on 01 February 2019

Improving biobutanol production in engineered Saccharomyces cerevisiae by manipulation of acetyl-CoA metabolism

scientific article published on 13 June 2013

Improving production of malonyl coenzyme A-derived metabolites by abolishing Snf1-dependent regulation of Acc1

scientific article (publication date: 6 May 2014)

Increased CO2 fixation enables high carbon-yield production of 3-hydroxypropionic acid in yeast

scientific article published in 2024

Lipid engineering combined with systematic metabolic engineering of Saccharomyces cerevisiae for high-yield production of lycopene

scientific article published on 22 November 2018

Metabolic engineering and transcriptomic analysis of Saccharomyces cerevisiae producing p-coumaric acid from xylose

scientific article published on 05 November 2019

Metabolic network remodelling enhances yeast’s fitness on xylose using aerobic glycolysis

scientific article published in 2021

Microbial acetyl-CoA metabolism and metabolic engineering

scientific article published on 05 December 2014

Modular Pathway Rewiring of Yeast for Amino Acid Production

scientific article published on 31 July 2018

Multidimensional engineering of Saccharomyces cerevisiae for efficient synthesis of medium-chain fatty acids ⬇️

scholarly article

Production of 3-hydroxypropionic acid from glucose and xylose by metabolically engineered Saccharomyces cerevisiae

Profiling of cytosolic and peroxisomal acetyl-CoA metabolism in Saccharomyces cerevisiae

scientific article

Rewiring Central Carbon Metabolism Ensures Increased Provision of Acetyl-CoA and NADPH Required for 3-OH-Propionic Acid Production

scientific article published on 13 November 2020

Rewiring carbon metabolism in yeast for high level production of aromatic chemicals

scientific article published on 31 October 2019

Thermotolerant yeasts selected by adaptive evolution express heat stress response at 30 °C.

scientific article published on 27 May 2016

Third-generation biorefineries as the means to produce fuels and chemicals from CO2

scientific article published on 18 March 2020

Yeast optimizes metal utilization based on metabolic network and enzyme kinetics

scientific article published on 23 March 2021

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