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List of works by Theodore G. Wensel

A GTPase-accelerating factor for transducin, distinct from its effector cGMP phosphodiesterase, in rod outer segment membranes

scientific article published on 01 November 1993

A Large Endoplasmic Reticulum-Resident Pool of TRPM1 in Retinal ON-Bipolar Cells.

scientific article published in May 2018

A comparison of the efficiency of G protein activation by ligand-free and light-activated forms of rhodopsin ⬇️

scientific article published on December 1, 1997

A nanosecond fluorescence depolarization study on the segmental flexibility of receptor-bound immunoglobulin E

scientific article published on 01 May 1990

A synaptic vesicle-associated Ca2+ channel promotes endocytosis and couples exocytosis to endocytosis.

scientific article

ABCA4 mutations causing mislocalization are found frequently in patients with severe retinal dystrophies

scientific article published on 15 August 2005

Abrupt onset of mutations in a developmentally regulated gene during terminal differentiation of post-mitotic photoreceptor neurons in mice

scientific article

Acceleration of key reactions as a strategy to elucidate the rate-limiting chemistry underlying phototransduction inactivation

scientific article published in March 2003

Activation mechanism of retinal rod cyclic GMP phosphodiesterase probed by fluorescein-labeled inhibitory subunit

scientific article published in February 1990

Activation of RGS9-1GTPase acceleration by its membrane anchor, R9AP

scientific article published on 30 January 2003

Activation-dependent hindrance of photoreceptor G protein diffusion by lipid microdomains

scientific article published on 18 August 2008

Biosynthesis of the unsaturated 14-carbon fatty acids found on the N termini of photoreceptor-specific proteins

scientific article published on 01 March 1996

Characterization of R9AP, a membrane anchor for the photoreceptor GTPase-accelerating protein, RGS9-1.

scientific article

Chronic cold exposure increases RGS7 expression and decreases alpha(2)-autoreceptor-mediated inhibition of noradrenergic locus coeruleus neurons

scientific article

Clearance of intravitreal moxifloxacin

scientific article published in January 2006

Co-expression of Gbeta5 enhances the function of two Ggamma subunit-like domain-containing regulators of G protein signaling proteins.

scientific article published on February 2000

Correction: the retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration

scientific article published on 28 May 2015

Cosegregation and functional analysis of mutant ABCR (ABCA4) alleles in families that manifest both Stargardt disease and age-related macular degeneration.

scientific article

Defective development of photoreceptor membranes in a mouse model of recessive retinal degeneration

scientific article published on 18 September 2006

Defining the layers of a sensory cilium with STORM and cryoelectron nanoscopy

scientific article published on 05 November 2019

Dependence of RGS9-1 membrane attachment on its C-terminal tail

scientific article published on 24 October 2001

Differential epitope masking reveals synapse-specific complexes of TRPM1.

scientific article

Diffusion-enhanced lanthanide energy-transfer study of DNA-bound cobalt(III) bleomycins: comparisons of accessibility and electrostatic potential with DNA complexes of ethidium and acridine orange.

scientific article published in June 1985

Distribution of RGS9-2 in neurons of the mouse striatum.

scientific article published on 11 November 2009

Do phosphatidylinositides modulate vertebrate phototransduction?

scientific article published in April 2000

Domain organization and conformational plasticity of the G protein effector, PDE6

scientific article published on July 2015

Domain organization and conformational plasticity of the G protein effector, PDE6.

scientific article published on 25 March 2015

Efficient mutagenesis of the rhodopsin gene in rod photoreceptor neurons in mice ⬇️

scientific article published on April 7, 2011

Electrostatic steering at acetylcholine binding sites

scientific article

Enhancement of phototransduction g protein-effector interactions by phosphoinositides

scientific article published on 29 December 2003

Enhancement of phototransduction protein interactions by lipid surfaces

scientific article published on 01 February 2000

Enhancement of rod outer segment GTPase accelerating protein activity by the inhibitory subunit of cGMP phosphodiesterase

scientific article published on 01 June 1994

Enzymology of GTPase acceleration in phototransduction

scientific article published on 01 January 2000

Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye.

scientific article

Evolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors

scientific article

Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions

scientific article

From molecules to behavior: new clues for RGS function in the striatum.

scientific article

Functional and structural studies of TRP channels heterologously expressed in budding yeast.

scientific article published on January 2011

GTPase regulators and photoresponses in cones of the eastern chipmunk.

scientific article published in February 2003

Heterogeneous N-terminal acylation of retinal proteins

scientific article

High affinity interactions of GTPgammaS with the heterotrimeric G protein, transducin. Evidence at high and low protein concentrations

scientific article published on 01 May 1996

High expression levels in cones of RGS9, the predominant GTPase accelerating protein of rods ⬇️

scientific article published on April 28, 1998

High-affinity triple helix formation by synthetic oligonucleotides at a site within a selectable mammalian gene.

scientific article published on May 1995

High-efficiency triple-helix-mediated photo-cross-linking at a targeted site within a selectable mammalian gene

scientific article published on 01 August 1996

How a G protein binds a membrane

scientific article published in June 2004

Identification of protein kinase C isozymes responsible for the phosphorylation of photoreceptor-specific RGS9-1 at Ser475.

scientific article

Inorganic pyrophosphatase from bovine retinal rod outer segments

scientific article published on 01 December 1992

Instability of GGL domain-containing RGS proteins in mice lacking the G protein beta-subunit Gbeta5

scientific article

Integrative subcellular proteomic analysis allows accurate prediction of human disease-causing genes

scientific article published on 24 February 2016

Kinetics of calcium channel opening by inositol 1,4,5-trisphosphate.

scientific article

Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina

scientific article published on 15 March 2007

Loss of Class III Phosphoinositide 3-Kinase Vps34 Results in Cone Degeneration

scientific article published on 07 November 2020

Low affinity interactions of GDPbetaS and ribose- or phosphoryl-substituted GTP analogues with the heterotrimeric G protein, transducin

scientific article published on 01 May 1996

Membrane stimulation of cGMP phosphodiesterase activation by transducin: comparison of phospholipid bilayers to rod outer segment membranes

scientific article published on 01 October 1992

Metabolizable 111In chelate conjugated anti-idiotype monoclonal antibody for radioimmunodetection of lymphoma in mice

scientific article published on 01 January 1986

Mislocalization and degradation of human P23H-rhodopsin-GFP in a knockin mouse model of retinitis pigmentosa

scientific article published on 28 December 2011

Modules in the photoreceptor RGS9-1.Gbeta 5L GTPase-accelerating protein complex control effector coupling, GTPase acceleration, protein folding, and stability

scientific article published on 01 November 2000

Multiphoton adaptation of a commercial low-cost confocal microscope for live tissue imaging

scientific article published in May 2009

Multiple zinc binding sites in retinal rod cGMP phosphodiesterase, PDE6alpha beta

scientific article published on 01 July 2000

N-myristoylation of the rod outer segment G protein, transducin, in cultured retinas

scientific article published on 01 November 1992

Neural reprogramming in retinal degeneration.

scientific article published on July 2007

Nicotinic acetylcholine receptor channel electrostatics determined by diffusion-enhanced luminescence energy transfer

scientific article published on 2 June 2006

Nonsense mutations in the rhodopsin gene that give rise to mild phenotypes trigger mRNA degradation in human cells by nonsense-mediated decay

scientific article published on 25 September 2015

Nucleotide exchange and cGMP phosphodiesterase activation by pertussis toxin inactivated transducin

scientific article published in December 1991

Oligomeric state of purified transient receptor potential melastatin-1 (TRPM1), a protein essential for dim light vision.

scientific article

Oral curcumin mitigates the clinical and neuropathologic phenotype of the Trembler-J mouse: a potential therapy for inherited neuropathy

scientific article

Phagocytosed photoreceptor outer segments activate mTORC1 in the retinal pigment epithelium

scientific article published on 29 May 2018

Phosphatidylinositol-3-phosphate is light-regulated and essential for survival in retinal rods

scientific article published on June 2016

Phosphoinositides in Retinal Function and Disease

scientific article published on 02 April 2020

Prediction and confirmation of a site critical for effector regulation of RGS domain activity

scientific article

Purification, reconstitution on lipid vesicles, and assays of PDE6 and its activator G protein, transducin

scientific article published in January 2005

R9AP stabilizes RGS11-G beta5 and accelerates the early light response of ON-bipolar cells

scientific article

RGS expression rate-limits recovery of rod photoresponses

scientific article published in August 2006

RGS function in visual signal transduction

scientific article published on 01 January 2002

RGS9, a GTPase accelerator for phototransduction

scientific journal article

RGS9-1 phosphorylation and Ca2+.

scientific article

Reciprocal control of retinal rod cyclic GMP phosphodiesterase by its gamma subunit and transducin

scientific article published in September 1986

Residues and residue pairs of evolutionary importance differentially direct signaling bias of D2 dopamine receptors

scientific article published on 01 November 2019

Retinal ganglion cells: development, function, and disease.

scientific article

Rhodopsin gene expression determines rod outer segment size and rod cell resistance to a dominant-negative neurodegeneration mutant

scientific article

Rhodopsin-EGFP knock-ins for imaging quantal gene alterations.

scientific article

SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium.

scientific article published on 13 June 2018

Safety and pharmokinetics of triamcinolone hexacetonide in rabbit eyes

scientific article

Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1.

scientific article published on February 2000

Structural and molecular bases of rod photoreceptor morphogenesis and disease.

scientific article published on 21 June 2016

Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A

scientific article

Structure of TRPV1 channel revealed by electron cryomicroscopy

scholarly article

Structure, alternative splicing, and expression of the human RGS9 gene

scientific article (publication date: 15 November 1999)

Structures of TRPV2 in distinct conformations provide insight into role of the pore turret

scientific article published on 31 December 2018

Subcellular compartmentalization of two calcium binding proteins, calretinin and calbindin-28 kDa, in ganglion and amacrine cells of the rat retina

scientific article

TRP channel gene expression in the mouse retina.

scientific article

Targeted expression of the dominant-negative FGFR4a in the eye using Xrx1A regulatory sequences interferes with normal retinal development

scientific article published in September 2003

Targeted generation of DNA strand breaks using pyrene-conjugated triplex-forming oligonucleotides

scientific article published on 13 May 2008

The nature of dominant mutations of rhodopsin and implications for gene therapy

scientific article published on October 2003

The ocular toxicity and pharmacokinetics of simvastatin following intravitreal injection in mice.

scientific article published on 18 September 2017

The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration

scientific article (publication date: April 2014)

Three-dimensional architecture of murine rod cilium revealed by cryo-EM.

scientific article published on January 2015

Three-dimensional architecture of the rod sensory cilium and its disruption in retinal neurodegeneration

scientific journal article

Timing is everything: GTPase regulation in phototransduction.

scientific article

Tokay gecko photoreceptors achieve rod-like physiology with cone-like proteins.

scientific article

Triplex targets in the human rhodopsin gene.

scientific article

Two R7 regulator of G-protein signaling proteins shape retinal bipolar cell signaling

scientific article published on June 2009

β2-Adrenergic receptor activation mobilizes intracellular calcium via a non-canonical cAMP-independent signaling pathway

scientific article published on 25 April 2017

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