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List of works by Elizabeth J. Ryan

17beta-estradiol (E2) modulates cytokine and chemokine expression in human monocyte-derived dendritic cells

scientific article

A respiratory challenge model for infection with Bordetella pertussis: application in the assessment of pertussis vaccine potency and in defining the mechanism of protective immunity.

scientific article published in January 1998

Altered expression of caspases-4 and -5 during inflammatory bowel disease and colorectal cancer: Diagnostic and therapeutic potential

scientific article published on 6 May 2015

Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure

scientific article published on 27 March 2008

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

scientific article

Booster immunization of children with an acellular pertussis vaccine enhances Th2 cytokine production and serum IgE responses against pertussis toxin but not against common allergens

scientific article

CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression.

scientific article

Caspase activity is required for stimulated B lymphocytes to enter the cell cycle

scientific article

Causes of genome instability: the effect of low dose chemical exposures in modern society

scientific article

Changes in endometrial natural killer cell expression of CD94, CD158a and CD158b are associated with infertility.

scientific article published in April 2009

Chemotherapy and repeat resection abrogate the prognostic value of neutrophil lymphocyte ratio in colorectal liver metastases

scientific article published on 27 September 2019

Chronic hepatitis C infection blocks the ability of dendritic cells to secrete IFN-α and stimulate T-cell proliferation

scientific article published on 14 March 2011

Colorectal Serrated Neoplasia: An Institutional 12-Year Review Highlights the Impact of a Screening Programme

scientific article published on 06 February 2019

DNA Methylation Profiling in Inflammatory Bowel Disease Provides New Insights into Disease Pathogenesis

scientific article published on 28 September 2015

DUBLIN [Degree of Ulcerative colitis Burden of Luminal Inflammation] Score, a Simple Method to Quantify Inflammatory Burden in Ulcerative Colitis

scientific article published on 01 October 2019

Dendritic cell inhibition correlates with survival of colorectal cancer patients on bevacizumab treatment

scientific article published on November 2012

Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4.

scientific article published on November 2002

Depleted polymorphonuclear leukocytes in human metastatic liver reflect an altered immune microenvironment associated with recurrent metastasis.

scientific article published on 23 March 2018

Differential expression of NK receptors CD94 and NKG2A by T cells in rheumatoid arthritis patients in remission compared to active disease.

scientific article

Distinct T-cell subtypes induced with whole cell and acellular pertussis vaccines in children

scientific article

Effect of chronic hepatitis C virus infection on bone disease in postmenopausal women

scientific article published on 24 January 2009

Elevated circulating osteoprotegerin and reduced matrix-metalloprotease-9 in post-menopausal women with chronic Hepatitis C virus infection

scientific article published on 3 August 2012

Enrichment of Inflammatory IL-17 and TNF-α Secreting CD4(+) T Cells within Colorectal Tumors despite the Presence of Elevated CD39(+) T Regulatory Cells and Increased Expression of the Immune Checkpoint Molecule, PD-1

scientific article published on 7 March 2016

Estrogen receptors and their implications in colorectal carcinogenesis

scientific article

Filamentous Hemagglutinin and Pertussis Toxin from Bordetella pertussis Modulate Immune Responses to Unrelated Antigens

article

Gastro-intestinal toxicity of chemotherapeutics in colorectal cancer: the role of inflammation.

scientific article published on April 2014

Gene profiling analysis of ALVAC infected human monocyte derived dendritic cells.

scientific article

HLA-DR expression in tumor epithelium is an independent prognostic indicator in esophageal adenocarcinoma patients.

scientific article

Heightened Expression of CD39 by Regulatory T Lymphocytes Is Associated with Therapeutic Remission in Inflammatory Bowel Disease.

scientific article

Hepatitis C virus targets the interferon-α JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes

scientific article published on 12 April 2013

Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta

scientific article published on October 2008

Human Tumor-Infiltrating Myeloid Cells: Phenotypic and Functional Diversity

scientific article published on 6 February 2017

Immune Cell Profiling of IFN-λ Response Shows pDCs Express Highest Level of IFN-λR1 and Are Directly Responsive via the JAK-STAT Pathway.

scientific article published on 12 September 2016

Immunomodulators and delivery systems for vaccination by mucosal routes.

scientific article

Inhibition of Dendritic Cell Maturation by the Tumor Microenvironment Correlates with the Survival of Colorectal Cancer Patients following Bevacizumab Treatment

scientific article published on 06 June 2012

Interferon-α suppressed granulocyte colony stimulating factor production is reversed by CL097, a TLR7/8 agonist

scientific article published in December 2010

KH-Type Splicing Regulatory Protein Controls Colorectal Cancer Cell Growth and Modulates the Tumor Microenvironment

scientific article published on 09 August 2019

Keeping the bowel regular: the emerging role of Treg as a therapeutic target in inflammatory bowel disease.

scientific article

Ligation of dendritic cell-associated lectin-1 induces partial maturation of human monocyte derived dendritic cells

scientific article

Lower Expression of Nrf2 MRNA in Older Donor Livers: A Possible Contributor to Increased Ischemia–Reperfusion Injury?

scientific article published on 01 November 2007

Macrophage- and dendritic cell--dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF.

scientific article published on 16 January 2003

Microsatellite instability is associated with reduced disease specific survival in stage III colon cancer

scientific article published on 22 June 2016

Organ preservation with local excision or active surveillance following chemoradiotherapy for rectal cancer

scientific article published on 20 December 2016

Orphan Nuclear Receptors in Colorectal Cancer

scientific article published on 28 June 2018

Personalised mapping of tumour development in synchronous colorectal cancer patients

scientific article published on 03 July 2020

Preclinical evaluation of the AR inhibitor enzalutamide in triple-negative breast cancer cells

scientific article

Rapid, early and sustained virological responses in a cohort of Irish patients treated with pegylated interferon and ribavirin for chronic hepatitis C virus infection

scientific article published on 29 October 2011

Reply to: “Dendritic cell subset composition in the human liver is more complex than it seems”

article

Role of myeloid regulatory cells (MRCs) in maintaining tissue homeostasis and promoting tolerance in autoimmunity, inflammatory disease and transplantation

scientific article published on 24 October 2018

Severe Symptomatic Primary CMV Infection in Inflammatory Bowel Disease Patients with Low Population Seroprevalence

scientific article published on 28 June 2018

Subcutaneous rather than intravenous ustekinumab induction is associated with comparable circulating drug levels and early clinical response: a pilot study

scientific article published on 19 June 2018

Systems biology analysis identifies molecular determinants of chemotherapy-induced diarrhoea

scientific article published on 17 December 2019

Targeting EGFR in metastatic colorectal cancer beyond the limitations of KRAS status: alternative biomarkers and therapeutic strategies.

scientific article published on January 2015

The Canarypox-virus vaccine vector ALVAC triggers the release of IFN-gamma by Natural Killer (NK) cells enhancing Th1 polarization

scientific article published on 17 January 2007

The affect of chronic hepatitis C infection on dendritic cell function: a summary of the experimental evidence.

scientific article published on 14 March 2011

The effect of environmental chemicals on the tumor microenvironment

scientific article

Transcriptional subtyping and CD8 immunohistochemistry identifies poor prognosis stage II/III colorectal cancer patients who benefit from adjuvant chemotherapy

scientific article published on 01 June 2018

Tumor Budding and PDC Grade Are Stage Independent Predictors of Clinical Outcome in Mismatch Repair Deficient Colorectal Cancer.

scientific article published on 3 November 2017

Tumor conditioned media from colorectal cancer patients inhibits dendritic cell maturation

scientific article published on August 2012

Tumour microenvironment of both early- and late-stage colorectal cancer is equally immunosuppressive

scientific article

Tumour tissue microenvironment can inhibit dendritic cell maturation in colorectal cancer

scientific article

Variant in CD209 promoter is associated with severity of liver disease in chronic hepatitis C virus infection

scientific article published on 12 May 2010

Visceral Adiposity is a Risk Factor for Poor Prognosis in Colorectal Cancer Patients Receiving Adjuvant Chemotherapy.

scientific article published on September 2015

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