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List of works by Linda A Sherman

A soluble single-chain T-cell receptor IL-2 fusion protein retains MHC-restricted peptide specificity and IL-2 bioactivity

scientific article published on 11 November 2003

A spontaneously arising pancreatic tumor does not promote the differentiation of naive CD8+ T lymphocytes into effector CTL.

scientific article published on June 2004

Activation of low avidity CTL specific for a self epitope results in tumor rejection but not autoimmunity

scientific article published on 01 January 1998

Adjuvants targeting innate and adaptive immunity synergize to enhance tumor immunotherapy

scholarly article

Alloantibodies can discriminate class I major histocompatibility complex molecules associated with various endogenous peptides

scientific article

Altered functional and biochemical response by CD8+ T cells that remain after tolerance

scientific article published in August 2001

Analysis of novel residues of class I involved in recognition by alloreactive T cells

scientific article published on 01 January 1990

Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex

scientific article published on April 1991

Antigen concentration and precursor frequency determine the rate of CD8+ T cell tolerance to peripherally expressed antigens

scientific article published on 01 July 1999

Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells.

scientific article published on 03 February 2014

B7-2 (CD86) controls the priming of autoreactive CD4 T cell response against pancreatic islets

article

CD4+ T Cells Pass Through an Effector Phase During the Process of In Vivo Tolerance Induction

scientific article published on 01 April 2003

CD4+ T-cell help in the tumor milieu is required for recruitment and cytolytic function of CD8+ T lymphocytes

scientific article published on 12 October 2010

CD8+ T cell tolerance in nonobese diabetic mice is restored by insulin-dependent diabetes resistance alleles.

scientific article published in August 2005

CRISPR-Cas9-Mediated Modification of the NOD Mouse Genome With Ptpn22R619W Mutation Increases Autoimmune Diabetes

scientific article published on 26 April 2016

CTLA-4 blockade enhances the CTL responses to the p53 self-tumor antigen.

scientific article published on March 2001

Cell-type-specific recognition of allogeneic cells by alloreactive cytotoxic T cells: a consequence of peptide-dependent allorecognition.

scientific article published on January 1991

Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: implications for gene therapy.

scientific article

Cellular mechanisms of restored β-cell tolerance mediated by protective alleles of Idd3 and Idd5

scientific article

Characterization of CD8+ T Lymphocytes That Persist After Peripheral Tolerance to a Self Antigen Expressed in the Pancreas

scientific article published on 01 January 2000

Comparing the relative role of perforin/granzyme versus Fas/Fas ligand cytotoxic pathways in CD8+ T cell-mediated insulin-dependent diabetes mellitus

scientific article published on 01 October 1999

Comparison of the H-2Kb-specific cytolytic T lymphocyte receptor repertoire in Igh recombinant strains

scientific article published on 01 June 1985

Conformational differences in major histocompatibility complex-peptide complexes can result in alloreactivity.

scientific article

Consequences of self-presentation of peptide antigen by cytolytic T lymphocytes

scientific article published on 01 September 1989

Contribution of TCR signaling strength to CD8+ T cell peripheral tolerance mechanisms

scientific article

Cooperation of Human Tumor-Reactive CD4+ and CD8+ T Cells after Redirection of Their Specificity by a High-Affinity p53A2.1-Specific TCR

scientific article published on 01 January 2005

Cytolytic T-lymphocyte response to isolated class I H-2 proteins and influenza peptides

scientific article published in July 1989

Defective CD8+ T Cell Peripheral Tolerance in Nonobese Diabetic Mice

scientific article published on 01 July 2001

Defects in deletional tolerance of CD8+ T cells in autoimmune diabetes.

scientific article

Deletion of Naive CD8 T Cells Requires Persistent Antigen and Is Not Programmed by an Initial Signal from the Tolerogenic APC

scientific article published on 01 December 2003

Dissection of the B10.D2 anti-H-2Kb cytolytic T lymphocyte receptor repertoire

scientific article published on June 1980

Distinct Requirements for Deletion versus Anergy during CD8 T Cell Peripheral Tolerance In Vivo

scientific article published on 01 February 2005

Expression of diabetes-associated genes by dendritic cells and CD4 T cells drives the loss of tolerance in nonobese diabetic mice

scientific article published on 10 July 2009

Extracellular processing of peptide antigens that bind class I major histocompatibility molecules

scientific article

Finding order in chaos

scientific article published on 3 April 2017

Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity.

scientific article published on 11 August 2013

Functional differences between low- and high-affinity CD8(+) T cells in the tumor environment

scientific article published on November 2012

Genetic and regulatory contributions of the major histocompatibility complex to the developing cytolytic T lymphocyte repertoire

scientific article published on 01 April 1982

Genetic interactions among Idd3, Idd5.1, Idd5.2, and Idd5.3 protective loci in the nonobese diabetic mouse model of type 1 diabetes

scientific article published on 20 February 2013

Genetic linkage of the cytolytic T lymphocyte repertoire and immunoglobulin heavy chain genes ⬇️

scientific article published on July 1, 1982

Home observations of family interactions of depressed women

scientific article

Human CD8 transgene regulation of HLA recognition by murine T cells ⬇️

scientific article published on November 1, 1995

Idd9.2 and Idd9.3 protective alleles function in CD4+ T-cells and nonlymphoid cells to prevent expansion of pathogenic islet-specific CD8+ T-cells.

scientific article

Identification and design of p53-derived HLA-A2-binding peptides with increased CTL immunogenicity.

scientific article published on April 2001

Identification of Her-2/Neu CTL epitopes using double transgenic mice expressing HLA-A2.1 and human CD.8.

scientific article published in February 1997

Immunologic effects of an orally available BRAFV600E inhibitor in BRAF wild-type murine models.

scientific article

Immunoselection of structural H-2Kb variants: Use of cloned cytolytic T cells to select for loss of a CTL-defined allodeterminant

scientific article published on 01 January 1986

Impact of distressed and aggressive behavior

scientific article

In a Transgenic Model of Spontaneous Autoimmune Diabetes, Expression of a Protective Class II MHC Molecule Results in Thymic Deletion of Diabetogenic CD8+ T Cells

scientific article published on 01 January 2004

Induction of allogeneic cytolytic T lymphocytes by partially purified membrane glycoproteins

scientific article published on 01 April 1980

Influence of the major histocompatibility complex on the repertoire of allospecific cytolytic T lymphocytes.

scientific article

Memory CD8(+) T cells undergo peripheral tolerance

scientific article published on July 2002

Molecular interactions required for triggering alloantigen-specific cytolytic T lymphocytes

scientific article published on 01 June 1989

Monoclonal anti-H-2Kb antibodies detect serological differences betweenH-2K b mutants

scientific article published on 01 January 1981

Monoclonal dinitrophenyl-specific murine IgE antibody: preparation, isolation, and characterization

scientific article published on 01 June 1980

Mutationally derived H-2 antigenic differences as defined by cytolytic T lymphocyte clones ⬇️

scientific article published on September 1, 1981

N-Terminal Trimer Extension of Nominal CD8 T Cell Epitopes Is Sufficient to Promote Cross-Presentation to Cognate CD8 T Cells In Vivo

scientific article published on 01 December 2007

PTPN22 alters the development of regulatory T cells in the thymus

scientific article

PTPN22 contributes to exhaustion of T lymphocytes during chronic viral infection.

scientific article published on 31 October 2016

PTPN22 controls the germinal center by influencing the numbers and activity of T follicular helper cells

scientific article published on 22 January 2014

Participation of the major histocompatibility complex in antibody recognition of viral antigens expressed on infected cells

scientific article published on February 1982

Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes

scientific article

Peripheral Deletion of CD8 T Cells Requires p38 MAPK in Cross-Presenting Dendritic Cells.

scientific article published in September 2017

Peripheral tolerance in transgenic mice: tolerance to class II MHC and non-MHC transgene antigens.

scientific article published on August 1991

Peripheral tolerance of CD8 T lymphocytes

scientific article

Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cells

scientific article published on 01 April 1992

Phenotypic and functional analysis of CD8(+) T cells undergoing peripheral deletion in response to cross-presentation of self-antigen.

scientific article

Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice

scientific article

Recognition of conformational determinants on H–2 by cytolytic T lymphocytes

scientific article published in Nature

Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR.

scientific article

Recognition of influenza-infected cells by cytolytic T lymphocyte clones: determinant selection by class I restriction elements

scientific article published on 01 October 1983

Redirecting effector T cells through their IL-2 receptors.

scientific article published on January 1999

Selecting T cell receptors with high affinity for self-MHC by decreasing the contribution of CD8.

scientific article

Strategies for tumor elimination by cytotoxic T lymphocytes.

scientific article published on January 1998

T-cell and B-cell responses to viral antigens at the clonal level.

scientific article

The Fate of Low Affinity Tumor-Specific CD8+ T Cells in Tumor-Bearing Mice

scientific article published on 01 March 2005

The Sequence Alteration Associated with a Mutational Hotspot in p53 Protects Cells From Lysis by Cytotoxic T Lymphocytes Specific for a Flanking Peptide Epitope ⬇️

scientific article published on September 21, 1998

The Use of Idd Congenic Mice to Identify Checkpoints of Peripheral Tolerance to Islet Antigen

scientific article published on 21 March 2007

The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development.

scientific article

The apoptotic pathway contributing to the deletion of naive CD8 T cells during the induction of peripheral tolerance to a cross-presented self-antigen

scientific article

The cytolytic T lymphocyte receptor repertoire of H-2 disparate cells obtained from double parent chimeras

scientific article published in March 1985

The effect of the autoimmunity-associated gene, PTPN22, on a BXSB-derived model of lupus

scientific article

The induction of cytolytic T lymphocytes with specificity for p-azophenylarsonate coupled syngeneic cells ⬇️

scientific article published on October 1, 1978

The induction of cytolytic T lymphocytes with syngeneic trinitrophenyl-coupled membranes ⬇️

scientific article published on July 1, 1979

The induction of secondary cytolytic T lymphocytes by solubilized membrane proteins ⬇️

scientific article published on March 1, 1978

The molecular basis of allorecognition

scientific article

The mouse mammary tumor virus env gene is the source of a CD8+ T-cell-stimulating peptide presented by a major histocompatibility complex class I molecule in a murine thymoma.

scientific article

The origin of strain-specific differences in the specificity repertoires of murine cytolytic T lymphocytes

scientific article

The role of Fas-FasL in CD8+ T-cell-mediated insulin-dependent diabetes mellitus (IDDM).

scientific article

Tissue-resident memory CD8+ T cells can be deleted by soluble, but not cross-presented antigen

scientific article published in November 2005

To Each (MHC Molecule) Its Own (Binding Motif)

scientific article published on 01 September 2006

Tolerance to p53 by A2.1-restricted cytotoxic T lymphocytes.

scientific article

Tumor-Specific CD4+ T Cells Render the Tumor Environment Permissive for Infiltration by Low-Avidity CD8+ T Cells

scientific article published on 01 March 2008

Type 1 diabetes pathogenesis is modulated by spontaneous autoimmune responses to endogenous retrovirus antigens in NOD mice

scientific article published on 13 January 2017

Uncoupling of proliferative potential and gain of effector function by CD8(+) T cells responding to self-antigens.

scientific article

Unrestricted recognition of a nonpeptide antigen by CD8+ cytolytic T lymphocytes.

scientific article published in December 1989

Using Autoimmunity To Inform Tumor Immunity.

scientific article published in December 2015

Wendy Havran 1955-2020

scientific article published on 01 April 2020

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