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List of works by Vaibhav B. Patel

A Disintegrin and Metalloprotease-17 Regulates Pressure Overload-Induced Myocardial Hypertrophy and Dysfunction Through Proteolytic Processing of Integrin β1.

scientific article

ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity

scientific article

Advanced iron-overload cardiomyopathy in a genetic murine model is rescued by resveratrol therapy.

scientific article published on 5 December 2017

Agonist-induced hypertrophy and diastolic dysfunction are associated with selective reduction in glucose oxidation: a metabolic contribution to heart failure with normal ejection fraction.

scientific article

Angiotensin 1-7 ameliorates diabetic cardiomyopathy and diastolic dysfunction in db/db mice by reducing lipotoxicity and inflammation.

scientific article

Angiotensin 1-7 mediates renoprotection against diabetic nephropathy by reducing oxidative stress, inflammation, and lipotoxicity

scientific article published on 19 February 2014

Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: a positive feedback mechanism in the RAS.

scientific article published on 9 December 2013

Angiotensin-converting enzyme 2 antagonizes angiotensin II-induced pressor response and NADPH oxidase activation in Wistar-Kyoto rats and spontaneously hypertensive rats

scientific article published on 29 June 2012

Angiotensin-converting enzyme 2 is a critical determinant of angiotensin II-induced loss of vascular smooth muscle cells and adverse vascular remodeling

scientific article published on 5 May 2014

Antagonism of angiotensin 1-7 prevents the therapeutic effects of recombinant human ACE2

scientific article

Beneficial effects of grape resveratrol on serum adiponectin and inflammation: clinical trial in patients with stable coronary artery disease: editorial to: "Grape resveratrol increases serum adiponectin and downregulates inflammatory genes in perip

scientific article

Cardioprotective and antihypertensive effects of Enicostemma littorale Blume extract in fructose-fed rats

scientific article published on 11 July 2012

Cardioprotective effect of melatonin against isoproterenol induced myocardial infarction in rats: A biochemical, electrocardiographic and histoarchitectural evaluation.

scientific article published on 13 July 2010

Cardioprotective effects mediated by angiotensin II type 1 receptor blockade and enhancing angiotensin 1-7 in experimental heart failure in angiotensin-converting enzyme 2-null mice

scientific article published on 16 April 2012

Differential role of TIMP2 and TIMP3 in cardiac hypertrophy, fibrosis, and diastolic dysfunction

scientific article published on 01 April 2014

Doxorubicin mediated cardiotoxicity in rats: protective role of felodipine on cardiac indices.

scientific article published on 22 July 2013

Dual loss of PI3Kα and PI3Kγ signaling leads to an age-dependent cardiomyopathy.

scientific article published on 24 October 2014

Epicardial adipose tissue as a metabolic transducer: role in heart failure and coronary artery disease

scientific article published on 31 July 2017

Females Are Protected From Iron-Overload Cardiomyopathy Independent of Iron Metabolism: Key Role of Oxidative Stress.

scientific article published on 23 January 2017

Heterozygote loss of ACE2 is sufficient to increase the susceptibility to heart disease

scientific article published on 15 April 2014

Hydrogen sulfide: an old gas with new cardioprotective effects.

scientific article published on March 2015

Inside(sight) of tiny communicator: exosome biogenesis, secretion, and uptake

scientific article published on 22 February 2020

Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy.

scientific article published on 7 December 2015

Loss of NOX2 (gp91phox) prevents oxidative stress and progression to advanced heart failure

scientific article published in September 2014

Loss of TIMP3 selectively exacerbates diabetic nephropathy

scientific article published on 15 August 2012

Loss of angiotensin-converting enzyme-2 exacerbates diabetic cardiovascular complications and leads to systolic and vascular dysfunction: a critical role of the angiotensin II/AT1 receptor axis

scientific article published on 03 April 2012

Loss of p47phox subunit enhances susceptibility to biomechanical stress and heart failure because of dysregulation of cortactin and actin filaments.

scientific article published on 3 April 2013

Murine recombinant angiotensin-converting enzyme 2 attenuates kidney injury in experimental Alport syndrome.

scientific article published on 26 February 2017

PI3Kα is essential for the recovery from Cre/tamoxifen cardiotoxicity and in myocardial insulin signalling but is not required for normal myocardial contractility in the adult heart

scientific article published on 24 January 2015

PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease

scientific article published in Nature Communications

Protective effect of Clerodendron glandulosum extract against experimentally induced metabolic syndrome in rats.

scientific article published on 15 September 2010

Recombinant Human ACE2 and the Angiotensin 1-7 Axis as Potential New Therapies for Heart Failure

scientific article published on 23 December 2016

Regulators of G-Protein Signaling 10 and Heart Failure: The Importance of Negative Regulators of Heart Disease.

scientific article

Response to Comment on Patel et al. ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity. Diabetes 2016;65:85-95.

scientific article published in February 2016

Role of ACE2 in diastolic and systolic heart failure.

scientific article published on September 2012

Role of angiotensin-converting enzyme 2 (ACE2) in diabetic cardiovascular complications.

scientific article published on April 2014

Role of the ACE2/Angiotensin 1-7 Axis of the Renin-Angiotensin System in Heart Failure

scientific article published on April 2016

Targeting angiotensin-converting enzyme 2 as a new therapeutic target for cardiovascular diseases.

scientific article published on 08 April 2014

Targeting the ACE2 and Apelin Pathways Are Novel Therapies for Heart Failure: Opportunities and Challenges.

scientific article published on 13 May 2012

Tissue Inhibitor of Matrix Metalloproteinase-1 Promotes Myocardial Fibrosis by Mediating CD63-Integrin β1 Interaction

scientific article published on 3 April 2017

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