List of works - Luis E Munoz

Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages

scientific article published on 11 March 2014

Activation of pregnane X receptor inhibits experimental dermal fibrosis

scientific article published on 4 January 2013

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines.

scientific article published on 28 April 2014

Altered glycan accessibility on native immunoglobulin G complexes in early rheumatoid arthritis and its changes during therapy.

scientific article

Altered glycosylation of complexed native IgG molecules is associated with disease activity of systemic lupus erythematosus

scientific article published on 11 November 2014

An impaired detection and clearance of dying cells can lead to the development of chronic autoimmunity

scientific article published in September 2005

An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity

scientific article

AnnexinA5 renders dead tumor cells immunogenic--implications for multimodal cancer therapies.

scientific article

Apoptosis and autoimmunity: when apoptotic cells break their silence.

scientific article published on August 2006

Apoptosis in the pathogenesis of systemic lupus erythematosus.

scientific article published on May 2008

Apoptotic cell clearance and its role in the origin and resolution of chronic inflammation.

scientific article published on 25 March 2015

Autoantibodies against galectin-2 peptides as biomarkers for the antiphospholipid syndrome

scientific article published on 01 June 2012

Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus

scientific article published on 11 August 2012

Autoimmunity and chronic inflammation - two clearance-related steps in the etiopathogenesis of SLE.

scientific article published on 09 September 2010

Autophagy regulates TNFα-mediated joint destruction in experimental arthritis.

scientific article

Bonding the foe - NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals

scientific article published on 10 December 2012

Clearance deficiency and systemic lupus erythematosus (SLE).

scientific article

Clearance deficiency--a potential link between infections and autoimmunity.

scientific article published on October 2008

Cleaved N-terminal histone tails distinguish between NADPH oxidase (NOX)-dependent and NOX-independent pathways of neutrophil extracellular trap formation

scientific article published on 17 August 2018

Colourful death: six-parameter classification of cell death by flow cytometry--dead cells tell tales.

scientific article

Connection between Periodontitis-Induced Low-Grade Endotoxemia and Systemic Diseases: Neutrophils as Protagonists and Targets

scientific article published in 2021

Cooperative binding of Annexin A5 to phosphatidylserine on apoptotic cell membranes

scientific article published on 4 December 2013

Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis

scientific article

Detection of low level cryoglobulins by flow cytometry.

scientific article

Do low vitamin D levels cause problems of waste removal in patients with SLE?

scientific article published on 27 October 2011

Dying autologous cells as instructors of the immune system

scientific article published on 01 January 2015

Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis

scientific article

Extracellular DNA traps in inflammation, injury and healing

scientific article published on 18 June 2019

Graphene Oxide Nanosheets for Localized Hyperthermia-Physicochemical Characterization, Biocompatibility, and Induction of Tumor Cell Death

scientific article published on 23 March 2020

Guidelines for the use of flow cytometry and cell sorting in immunological studies

scientific article published on October 2017

IgA subclasses have different effector functions associated with distinct glycosylation profiles

scientific article published on 08 January 2020

IgA2 Antibodies against SARS-CoV-2 Correlate with NET Formation and Fatal Outcome in Severely Diseased COVID-19 Patients

scientific article published on 12 December 2020

IgG autoantibodies bound to surfaces of necrotic cells and complement C4 comprise the phagocytosis promoting activity for necrotic cells of systemic lupus erythaematosus sera

scientific article published on 28 December 2007

IgG opsonized nuclear remnants from dead cells cause systemic inflammation in SLE

scientific article published on 01 April 2010

Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE

scientific article published on 08 December 2008

Inefficient clearance of dying cells and autoreactivity.

scientific article

Inefficient clearance of dying cells in patients with SLE: anti-dsDNA autoantibodies, MFG-E8, HMGB-1 and other players.

scientific article

Inflammatory clearance of apoptotic remnants in systemic lupus erythematosus (SLE).

scientific article published on 12 August 2008

Inhibition of hedgehog signaling for the treatment of murine sclerodermatous chronic graft-versus-host disease

scientific article published on 22 August 2012

Loading of nuclear autoantigens prototypically recognized by systemic lupus erythematosus sera into late apoptotic vesicles requires intact microtubules and myosin light chain kinase activity.

scientific article published on January 2015

Macrophages discriminate glycosylation patterns of apoptotic cell-derived microparticles

scientific article

Microvesicles from cerebrospinal fluid of patients with Alzheimer's disease display reduced concentrations of tau and APP protein

scientific article published on 08 May 2019

Milk fat globule-EGF factor 8 mediates the enhancement of apoptotic cell clearance by glucocorticoids.

scientific article published on 5 July 2013

MoMa from patients with systemic lupus erythematosus show altered adhesive activity

scientific article published in May 2009

Model systems for rapid and slow induction of apoptosis obtained by inducible expression of pro-apoptotic proteins.

scientific article published on 25 January 2013

Neutrophil Extracellular Traps (NETs) in the Cerebrospinal Fluid Samples from Children and Adults with Central Nervous System Infections

scientific article published on 23 December 2019

Neutrophil Extracellular Traps Promote the Development and Growth of Human Salivary Stones

scientific article published on 22 September 2020

Opsonization by anti-dsDNA antibodies of apoptotic cells in systemic lupus erythematosus

scientific article published on 01 June 2007

Patients with unstable angina pectoris show an increased frequency of the Fc gamma RIIa R131 allele

scientific article published on 20 June 2012

Phospholipids: key players in apoptosis and immune regulation.

scientific article

Photopheresis with UV-A light and 8-methoxypsoralen leads to cell death and to release of blebs with anti-inflammatory phenotype in activated and non-activated lymphocytes.

scientific article published on 6 June 2009

Redox modulation of HMGB1-related signaling

scientific article published on 19 March 2013

Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus

scientific article published in June 2009

Removal of dying cells and systemic lupus erythematosus

scientific article published on 01 January 2005

Role of guanylate binding protein-1 in vascular defects associated with chronic inflammatory diseases.

scientific article published on July 2011

Scent of dying cells: the role of attraction signals in the clearance of apoptotic cells and its immunological consequences.

scientific article

Sialylation of anti-histone immunoglobulin G autoantibodies determines their capabilities to participate in the clearance of late apoptotic cells

scientific article published on 27 January 2016

Sodium and potassium urate crystals differ in their inflammatory potential

scientific article published in May 2009

Sodium overload and water influx activate the NALP3 inflammasome

scientific article

Surface code--biophysical signals for apoptotic cell clearance.

scientific article

The Pathogenicity of Anti-β2GP1-IgG Autoantibodies Depends on Fc Glycosylation

scientific article published on 22 June 2015

The immune reaction against allogeneic necrotic cells is reduced in Annexin A5 knock out mice whose macrophages display an anti-inflammatory phenotype.

scientific article

The influence on the immunomodulatory effects of dying and dead cells of Annexin V.

scientific article published on 27 September 2006

The low-throughput protein A adsorber: an immune modulatory device. Hypothesis for the mechanism of action in the treatment of rheumatoid arthritis

scientific article published in January 2005

The role of annexin A5 in the modulation of the immune response against dying and dead cells

scientific article published on January 2007

The role of dead cell clearance in the etiology and pathogenesis of systemic lupus erythematosus: dendritic cells as potential targets

scientific article published on August 2014

The role of defective clearance of apoptotic cells in systemic autoimmunity.

scientific article published on May 2010

The uptake by blood-borne phagocytes of monosodium urate is dependent on heat-labile serum factor(s) and divalent cations

scientific article published on 01 April 2010

Treatment with DNAse I fosters binding to nec PBMC of CRP

scientific article published on 01 May 2009

Tumor immunotherapy: lessons from autoimmunity

scientific article

UVB-irradiated apoptotic cells induce accelerated growth of co-implanted viable tumor cells in immune competent mice.

scientific article published on 8 February 2013

Unconventional apoptosis of polymorphonuclear neutrophils (PMN): staurosporine delays exposure of phosphatidylserine and prevents phagocytosis by MΦ-2 macrophages of PMN.

scientific article

When autologous chromatin becomes a foe

scientific article published on 17 September 2012

Working with "H2S": facts and apparent artifacts.

scientific article

[The role of incomplete clearance of apoptotic cells in the etiology and pathogenesis of SLE]

scientific article published on 01 March 2010

List of works by Luis E Munoz

Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages

Activation of pregnane X receptor inhibits experimental dermal fibrosis

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines.

Altered glycan accessibility on native immunoglobulin G complexes in early rheumatoid arthritis and its changes during therapy.

Altered glycosylation of complexed native IgG molecules is associated with disease activity of systemic lupus erythematosus

An impaired detection and clearance of dying cells can lead to the development of chronic autoimmunity

An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity

AnnexinA5 renders dead tumor cells immunogenic--implications for multimodal cancer therapies.

Apoptosis and autoimmunity: when apoptotic cells break their silence.

Apoptosis in the pathogenesis of systemic lupus erythematosus.

Apoptotic cell clearance and its role in the origin and resolution of chronic inflammation.

Autoantibodies against galectin-2 peptides as biomarkers for the antiphospholipid syndrome

Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus

Autoimmunity and chronic inflammation - two clearance-related steps in the etiopathogenesis of SLE.

Autophagy regulates TNFα-mediated joint destruction in experimental arthritis.

Bonding the foe - NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals

Clearance deficiency and systemic lupus erythematosus (SLE).

Clearance deficiency--a potential link between infections and autoimmunity.

Cleaved N-terminal histone tails distinguish between NADPH oxidase (NOX)-dependent and NOX-independent pathways of neutrophil extracellular trap formation

Colourful death: six-parameter classification of cell death by flow cytometry--dead cells tell tales.

Connection between Periodontitis-Induced Low-Grade Endotoxemia and Systemic Diseases: Neutrophils as Protagonists and Targets

Cooperative binding of Annexin A5 to phosphatidylserine on apoptotic cell membranes

Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis

Detection of low level cryoglobulins by flow cytometry.

Do low vitamin D levels cause problems of waste removal in patients with SLE?

Dying autologous cells as instructors of the immune system

Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis

Extracellular DNA traps in inflammation, injury and healing

Graphene Oxide Nanosheets for Localized Hyperthermia-Physicochemical Characterization, Biocompatibility, and Induction of Tumor Cell Death

Guidelines for the use of flow cytometry and cell sorting in immunological studies

IgA subclasses have different effector functions associated with distinct glycosylation profiles

IgA2 Antibodies against SARS-CoV-2 Correlate with NET Formation and Fatal Outcome in Severely Diseased COVID-19 Patients

IgG autoantibodies bound to surfaces of necrotic cells and complement C4 comprise the phagocytosis promoting activity for necrotic cells of systemic lupus erythaematosus sera

IgG opsonized nuclear remnants from dead cells cause systemic inflammation in SLE

Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE

Inefficient clearance of dying cells and autoreactivity.

Inefficient clearance of dying cells in patients with SLE: anti-dsDNA autoantibodies, MFG-E8, HMGB-1 and other players.

Inflammatory clearance of apoptotic remnants in systemic lupus erythematosus (SLE).

Inhibition of hedgehog signaling for the treatment of murine sclerodermatous chronic graft-versus-host disease

Loading of nuclear autoantigens prototypically recognized by systemic lupus erythematosus sera into late apoptotic vesicles requires intact microtubules and myosin light chain kinase activity.

Macrophages discriminate glycosylation patterns of apoptotic cell-derived microparticles

Microvesicles from cerebrospinal fluid of patients with Alzheimer's disease display reduced concentrations of tau and APP protein

Milk fat globule-EGF factor 8 mediates the enhancement of apoptotic cell clearance by glucocorticoids.

MoMa from patients with systemic lupus erythematosus show altered adhesive activity

Model systems for rapid and slow induction of apoptosis obtained by inducible expression of pro-apoptotic proteins.

Neutrophil Extracellular Traps (NETs) in the Cerebrospinal Fluid Samples from Children and Adults with Central Nervous System Infections

Neutrophil Extracellular Traps Promote the Development and Growth of Human Salivary Stones

Opsonization by anti-dsDNA antibodies of apoptotic cells in systemic lupus erythematosus

Patients with unstable angina pectoris show an increased frequency of the Fc gamma RIIa R131 allele

Phospholipids: key players in apoptosis and immune regulation.

Photopheresis with UV-A light and 8-methoxypsoralen leads to cell death and to release of blebs with anti-inflammatory phenotype in activated and non-activated lymphocytes.

Redox modulation of HMGB1-related signaling

Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus

Removal of dying cells and systemic lupus erythematosus

Role of guanylate binding protein-1 in vascular defects associated with chronic inflammatory diseases.

Scent of dying cells: the role of attraction signals in the clearance of apoptotic cells and its immunological consequences.

Sialylation of anti-histone immunoglobulin G autoantibodies determines their capabilities to participate in the clearance of late apoptotic cells

Sodium and potassium urate crystals differ in their inflammatory potential

Sodium overload and water influx activate the NALP3 inflammasome

Surface code--biophysical signals for apoptotic cell clearance.

The Pathogenicity of Anti-β2GP1-IgG Autoantibodies Depends on Fc Glycosylation

The immune reaction against allogeneic necrotic cells is reduced in Annexin A5 knock out mice whose macrophages display an anti-inflammatory phenotype.

The influence on the immunomodulatory effects of dying and dead cells of Annexin V.

The low-throughput protein A adsorber: an immune modulatory device. Hypothesis for the mechanism of action in the treatment of rheumatoid arthritis

The role of annexin A5 in the modulation of the immune response against dying and dead cells

The role of dead cell clearance in the etiology and pathogenesis of systemic lupus erythematosus: dendritic cells as potential targets

The role of defective clearance of apoptotic cells in systemic autoimmunity.

The uptake by blood-borne phagocytes of monosodium urate is dependent on heat-labile serum factor(s) and divalent cations

Treatment with DNAse I fosters binding to nec PBMC of CRP

Tumor immunotherapy: lessons from autoimmunity

UVB-irradiated apoptotic cells induce accelerated growth of co-implanted viable tumor cells in immune competent mice.

Unconventional apoptosis of polymorphonuclear neutrophils (PMN): staurosporine delays exposure of phosphatidylserine and prevents phagocytosis by MΦ-2 macrophages of PMN.

When autologous chromatin becomes a foe

Working with "H2S": facts and apparent artifacts.

[The role of incomplete clearance of apoptotic cells in the etiology and pathogenesis of SLE]