Search filters

List of works by Garland R. Marshall

3D model for TM region of the AT-1 receptor in complex with angiotensin II independently validated by site-directed mutagenesis data.

scientific article

3D modeling of the activated states of constitutively active mutants of rhodopsin

scientific article published on 25 April 2006

3D-QSAR: a current perspective

scientific article published on September 1995

A crowdsourcing evaluation of the NIH chemical probes

scientific article (publication date: July 2009)

A minimalistic 3D pharmacophore model for cyclopentapeptide CXCR4 antagonists

scientific article published on 01 January 2006

A potential smoothing algorithm accurately predicts transmembrane helix packing

scientific article published in January 1999

A second look at mini-protein stability: analysis of FSD-1 using circular dichroism, differential scanning calorimetry, and simulations.

scientific article

A unique geometry of the active site of angiotensin-converting enzyme consistent with structure-activity studies

scientific article published in April 1987

A virtual library of constrained cyclic tetrapeptides that mimics all four side-chain orientations for over half the reverse turns in the protein data bank.

scientific article

Alpha/3(10)-helix transitions in alpha-methylalanine homopeptides: conformational transition pathway and potential of mean force

scientific article published in January 1994

Alternate binding mode of C-terminal phenethylamine analogs of G(t)alpha(340-350) to photoactivated rhodopsin

scientific article published on 01 December 2006

An Automated Strategy for Binding-Pose Selection and Docking Assessment in Structure-Based Drug Design.

scientific article

Angiotensin III-induced prostaglandin (PG) release

scientific article published on 01 January 1976

Antimycobacterial pyrroles: synthesis, anti-Mycobacterium tuberculosis activity and QSAR studies.

scientific article published in June 2000

Back to the future: ribonuclease A

scientific article

C-terminally shortened alamethicin on templates: influence of the linkers on conductances

scientific article published on August 1999

Calibration of effective van der Waals atomic contact radii for proteins and peptides

scientific article published on 01 January 1987

Cavity search: an algorithm for the isolation and display of cavity-like binding regions

scientific article published in December 1990

Characterization of central angiotensin II receptors involved in the elicitation of drinking in the rat.

scientific article published in January 1973

Comprehensive model of wild-type and mutant HIV-1 reverse transciptases.

scientific article

Computer-aided molecular modeling of a D2-agonist dopamine pharmacophore.

scientific article published on July 1987

Conformational templates for rational drug design: flexibility of cyclo(D-Pro1-Ala2-Ala3-Ala4-Ala5) in DMSO solution

scientific article published on 11 May 2007

Conformationally restricted TRH analogs: a probe for the pyroglutamate region

scientific article published on 01 April 1996

Conformationally restricted TRH analogues: constraining the pyroglutamate region

scientific article

Constrained search of conformational hyperspace

scientific article published on 01 March 1989

Cromolyn sodium nasal solution in the prophylactic treatment of pollen-induced seasonal allergic rhinitis

scientific article

DBMAKER: a set of programs to generate three-dimensional databases based upon user-specified criteria

scientific article published on 01 February 1995

Derivation of a three-dimensional pharmacophore model of substance P antagonists bound to the neurokinin-1 receptor

scientific article published on 01 September 1998

Design and Synthesis of Simplified Largazole Analogues as Isoform-Selective Human Lysine Deacetylase Inhibitors

scientific article published on 07 January 2016

Design, synthesis and QSAR studies on N-aryl heteroarylisopropanolamines, a new class of non-peptidic HIV-1 protease inhibitors

scientific article

Design, synthesis, and metal binding of novel Pseudo- oligopeptides containing two phosphinic acid groups

scientific article published in January 2008

Development of small molecules designed to modulate protein-protein interactions

scientific article published on 01 February 2006

Difference between restoring and predicting 3D structures of the loops in G-protein-coupled receptors by molecular modeling

scientific article published on July 2011

Do benzodiazepines mimic reverse-turn structures?

scientific article

Drug-like leads for steric discrimination between substrate and inhibitors of human acetylcholinesterase

scientific article published on 22 August 2011

Effect of glutathione on cyclic nucleotide levels in hydra attenuata

Efficient regioselective synthesis of enantiomerically pure 4-hydroxymethyl-Δ2-thiazoline

Electron paramagnetic resonance studies of functionally active, nitroxide spin-labeled peptide analogues of the C-terminus of a G-protein alpha subunit

scientific article published on August 2010

Engineering cyclic tetrapeptides containing chimeric amino acids as preferred reverse-turn scaffolds

scientific article published in January 2006

Engineering metal complexes of chiral pentaazacrowns as privileged reverse-turn scaffolds

scientific article published in February 2007

Erratum: A crowdsourcing evaluation of the NIH chemical probes

article

Expressed protein ligation to study protein interactions: semi-synthesis of the G-protein alpha subunit.

scientific article

FOUNDATION: a program to retrieve all possible structures containing a user-defined minimum number of matching query elements from three-dimensional databases

scientific article published on February 1993

Facilitated synthesis of peptaibols: alamethicin via enzymatic segment condensation.

scientific article

HIV-1 protease inhibitors: ketomethylene isosteres with unusually high affinity compared with hydroxyethylene isostere analogs.

scientific article published on September 1994

Helix stability of oligoglycine, oligoalanine, and oligo-β-alanine dodecamers reflected by hydrogen-bond persistence

scientific article published on 20 September 2014

High-resolution crystal structures of protein helices reconciled with three-centered hydrogen bonds and multipole electrostatics

scientific article published on 20 April 2015

Histone Deacetylase Inhibitors: Structure-Based Modeling and Isoform-Selectivity Prediction ⬇️

scientific article published on July 19, 2012

Hydroxamate analog libraries and evaluation of their iron affinity

scientific article

Impact of azaproline on Peptide conformation.

scientific article

Impact of azaproline on amide cis-trans isomerism: conformational analyses and NMR studies of model peptides including TRH analogues.

scientific article

Impact of cis-proline analogs on peptide conformation

scientific article published in April 2006

Inhibition of bacterial virulence: drug-like molecules targeting the Salmonella enterica PhoP response regulator

scientific article

Insight into the binding mode for cyclopentapeptide antagonists of the CXCR4 receptor

scientific article published in May 2006

Interactions between conserved residues in transmembrane helices 2 and 7 during angiotensin AT1 receptor activation

scientific article published on 01 November 2006

Light-activated rhodopsin induces structural binding motif in G protein α subunit ⬇️

scientific article published on April 14, 1998

Limiting assumptions in structure-based design: binding entropy ⬇️

scientific article published on 03 January 2012

Mechanism and modification of bradykinin-induced coronary vasodilation ⬇️

scientific article published on June 1, 1975

Metal complexes of chiral pentaazacrowns as conformational templates for beta-turn recognition

scientific article published in August 2002

Modeling molecular mechanisms of binding of the anaphylatoxin C5a to the C5a receptor

scientific article published on 15 February 2008

Modeling of the complex between transducin and photoactivated rhodopsin, a prototypical G-protein-coupled receptor

scientific article published on 31 March 2007

Modeling the possible conformations of the extracellular loops in G-protein-coupled receptors

scientific article published on February 2010

Modulating G-protein coupled receptor/G-protein signal transduction by small molecules suggested by virtual screening

scientific article

Molecular Modeling Suggests Conformational Scaffolds Specifically Targeting Five Subtypes of Somatostatin Receptors

scientific article published on 01 March 2007

Molecular dynamics of β-hairpin models of epigenetic recognition motifs

scientific article published on 17 September 2012

Molecular mechanisms of constitutive activity: mutations at position 111 of the angiotensin AT1 receptor

scientific article published on November 2005

Motion of carboxyl terminus of Galpha is restricted upon G protein activation. A solution NMR study using semisynthetic Galpha subunits.

scientific article

Novel cyclic analogs of angiotensin II with cyclization between positions 5 and 7: conformational and biological implications

scientific article published on 01 July 1996

PHOENIX: a scoring function for affinity prediction derived using high-resolution crystal structures and calorimetry measurements

scientific article

Partial sequence of rat prothrombin and the activity of two related pentapeptides as substrates for the vitamin K-dependent carboxylase system

scientific article published in March 1977

Peptide-bond modification for metal coordination: peptides containing two hydroxamate groups.

scientific article published in January 2003

Privileged scaffolds targeting reverse-turn and helix recognition.

scientific article published on January 2008

ProVal: a protein-scoring function for the selection of native and near-native folds

scientific article published on 01 February 2004

Prostaglandin release from vasculature by angiotensin II: dissociation from lipolysis

scientific article published on 01 September 1973

Protein recognition motifs: design of peptidomimetics of helix surfaces

scientific article published on 01 July 2007

Relative strength of cation-pi vs salt-bridge interactions: the Gtalpha(340-350) peptide/rhodopsin system.

scientific article published in June 2006

Renal concentrations of prostaglandin E in acute and chronic renal ischemia

scientific article published in November 1972

SKATE: a docking program that decouples systematic sampling from scoring

scientific article published on November 2010

Sampling conformational hyperspace: techniques for improving completeness

scientific article published in December 1995

Simplified modeling approach suggests structural mechanisms for constitutive activation of the C5a receptor

scientific article published on 30 November 2010

Solid-phase synthesis of methyl carboxymycobactin T 7 and analogues as potential antimycobacterial agents

scientific article

Solid-phase synthesis: a paradigm shift.

scientific article published on September 2003

Solvent exposure of specific nuclei of angiotensin II determined by NMR solvent saturation method

scientific article published in Nature

Stimulation of splenic prostaglandin release by angiotensin and specific inhibition by cysteine 8-AII

scientific article published on 01 January 1973

Structure of Alamethicin in solution. One- and two-dimensional 1H nuclear magnetic resonance studies at 500 MHz.

scientific article published on April 1983

Structures from NMR distance constraints

scientific article published on 01 July 1990

Synthesis of cyclic peptides on dual function supports

scientific article published on 01 June 1970

Targeting Lysine Deacetylases (KDACs) in Parasites

scientific article

Targeting the dimerization of epidermal growth factor receptors with small-molecule inhibitors

scientific article

The development and application of a novel safety-catch linker for BOC-based assembly of libraries of cyclic peptides.

scientific article

The early years--across the bench from Bruce (1963-1966).

scientific article

The utility of side-chain cyclization in determining the receptor-bound conformation of peptides: cyclic tripeptides and angiotensin II

scientific article published on 01 November 1992

The veil of commercialism

scientific article

Therapeutic approaches to human immunodeficiency virus: structural studies on G-protein-coupled receptors.

scientific article published on October 1997

Three-dimensional model for meta-II rhodopsin, an activated G-protein-coupled receptor

scientific article published in August 2003

Three-dimensional quantitative structure-activity relationship of human immunodeficiency virus (I) protease inhibitors. 2. Predictive power using limited exploration of alternate binding modes

scientific article published in July 1994

Three-dimensional recognition requirements for angiotensin agonists: a novel solution for an old problem

scientific article published on 01 August 1993

Three-dimensional structure-activity relationships

scientific article published on August 1988

Tracheal cytotoxin structural requirements for respiratory epithelial damage in pertussis

scientific article published on 01 May 1995

Validated ligand mapping of ACE active site

scientific article published in August 2005

Virtual screening for lead discovery

scientific article

c[D-pro-Pro-D-pro-N-methyl-Ala] adopts a rigid conformation that serves as a scaffold to mimic reverse-turns

scientific article published in January 2008

gamma-Glutamyl transpeptidase in Hydra

scientific article published on November 1976

Paulina is supported by:

About Paulina

Help