Search filters

List of works by Damjana Rozman

A cAMP-responsive element binding site is essential for sterol regulation of the human lanosterol 14alpha-demethylase gene (CYP51).

scientific article published on August 2002

A functional cytochrome P450 lanosterol 14 alpha-demethylase CYP51 enzyme in the acrosome: transport through the Golgi and synthesis of meiosis-activating sterols.

scientific article published on 20 November 2003

Acrolein consumption induces systemic dyslipidemia and lipoprotein modification

scientific article (publication date: 15 February 2010)

Acrolein-induced dyslipidemia and acute-phase response are independent of HMG-CoA reductase.

scientific article published on 3 August 2011

Adaptation of cholesterol synthesis to fasting and TNF-alpha: profiling cholesterol intermediates in the liver, brain, and testis

scientific article published on 3 March 2010

Altered expression of the steroid bioconverting pathway in pAN 7-1 transformants of Cochliobolus lunatus

scientific article published in November 1991

Amyloid precursor protein α- and β-cleaved ectodomains exert opposing control of cholesterol homeostasis via SREBP2.

scientific article published on 18 November 2013

An algorithm for rapid computational construction of metabolic networks: a cholesterol biosynthesis example

scientific article published on 16 March 2013

CREM modulates the circadian expression of CYP51, HMGCR and cholesterogenesis in the liver

scientific article published on 4 September 2008

CYP53A15 of Cochliobolus lunatus, a target for natural antifungal compounds.

scientific article

Characteristics of the heterologously expressed human lanosterol 14alpha-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human and Candida albicans CYP51 with azole antifungal agents

scientific article

Cholesterogenic genes expression in brain and liver of ganglioside-deficient mice.

scientific article published on 6 July 2012

Circadian Regulation of the Hepatic Endobiotic and Xenobitoic Detoxification Pathways: The Time Matters ⬇️

scientific article published on February 24, 2012

Circadian events in human diseases and in cytochrome P450-related drug metabolism and therapy.

scientific article published on 03 April 2013

Circadian expression of steroidogenic cytochromes P450 in the mouse adrenal gland--involvement of cAMP-responsive element modulator in epigenetic regulation of Cyp17a1.

scientific article published on 26 September 2011

Circadian rhythm of cholesterol synthesis in mouse liver: a statistical analysis of the post-squalene metabolites in wild-type and Crem-knock-out mice.

scientific article published on 21 April 2011

Combinations of genetic changes in the human cAMP-responsive element modulator gene: a clue towards understanding some forms of male infertility?

scientific article published in August 2005

Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells.

scientific article

Crosstalk between cholesterol homeostasis and drug metabolism

scientific article published in July 2008

Cumulus cells gene expression profiling in terms of oocyte maturity in controlled ovarian hyperstimulation using GnRH agonist or GnRH antagonist.

scientific article

Cyclic adenosine 3',5'-monophosphate(cAMP)/cAMP-responsive element modulator (CREM)-dependent regulation of cholesterogenic lanosterol 14alpha-demethylase (CYP51) in spermatids

scientific article published in November 1999

Defects in cholesterol synthesis genes in mouse and in humans: lessons for drug development and safer treatments.

scientific article published on February 2011

Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor

scientific article

Dehydroepiandrosterone post-transcriptionally modifies CYP1A2 induction involving androgen receptor

scientific article published on 17 April 2013

Disrupting Hepatocyte Cyp51 from Cholesterol Synthesis Leads to Progressive Liver Injury in the Developing Mouse and Decreases RORC Signalling

scientific article published on 18 January 2017

Drug interaction potential of 2-((3,4-dichlorophenethyl)(propyl)amino)-1-(pyridin-3-yl)ethanol (LK-935), the novel nonstatin-type cholesterol-lowering agent

scientific article published on 29 October 2008

Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers

scientific article published on 19 August 2009

Elevated expression of lanosterol 14alpha-demethylase (CYP51) and the synthesis of oocyte meiosis-activating sterols in postmeiotic germ cells of male rats

scientific article published in May 1998

Expression of microsomal lanosterol 14alpha-demethylase (CYP51) in an engineered soluble monomeric form.

scientific article published on 6 May 2008

Follicular sterol composition in gonadotrophin stimulated women with polycystic ovarian syndrome

scientific article published on 3 March 2006

From Nonalcoholic Fatty Liver Disease to Hepatocellular Carcinoma: A Systems Understanding

scientific article published on 01 February 2014

Functional genomics approaches to studies of the cytochrome p450 superfamily.

scientific article published on January 2007

Genomic aspects of NAFLD pathogenesis.

scientific article published on 29 March 2013

Heterologous transformation of Cochliobolus lunatus.

scientific article published in January 1991

Inducible cAMP Early Repressor Regulates the Period 1 Gene of the Hepatic and Adrenal Clocks ⬇️

scientific article published on February 25, 2013

Inhibition of human sterol Δ7-reductase and other postlanosterol enzymes by LK-980, a novel inhibitor of cholesterol synthesis.

scientific article published on 15 October 2010

Initiation of steroidogenesis precedes expression of cholesterologenic enzymes in the fetal mouse testes.

scientific article published on 28 September 2009

Investigation of the CYP2C9 induction profile in human hepatocytes by combining experimental and modelling approaches.

scientific article published on December 2009

Isolation of genomic DNA from filamentous fungi with high glucan level

scientific article published on 01 March 1994

Lanosterol 14alpha-demethylase (CYP51) and spermatogenesis

scientific article published on 01 December 1998

Lanosterol 14alpha-demethylase (CYP51), NADPH-cytochrome P450 reductase and squalene synthase in spermatogenesis: late spermatids of the rat express proteins needed to synthesize follicular fluid meiosis activating sterol

scientific article published in August 2000

Lanosterol 14alpha-demethylase and MAS sterols in mammalian gametogenesis

scientific article published in February 2002

Lanosterol metabolism and sterol regulatory element binding protein (SREBP) expression in male germ cell maturation

scientific article published in June 2003

Large-scale computational models of liver metabolism: How far from the clinics?

scientific article

Low nucleotide variability of CYP51A1 in humans: meta-analysis of cholesterol and bile acid synthesis and xenobiotic metabolism pathways

scientific article published in January 2013

Male germ cell-specific knockout of cholesterogenic cytochrome P450 lanosterol 14α-demethylase (Cyp51) ⬇️

scientific article published on March 18, 2013

Mammalian cytochromes P450--importance of tissue specificity.

scientific article published on 3 October 2006

Molecular Interactions between NAFLD and Xenobiotic Metabolism.

scientific article published on 22 January 2013

Molecular cloning and partial characterisation of the mouse Cyp51 cDNA

scientific article published on 01 January 2000

Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndrome

scientific article

New aspects on lanosterol 14alpha-demethylase and cytochrome P450 evolution: lanosterol/cycloartenol diversification and lateral transfer

scientific article published in July 2004

New steroid 5alpha-reductase type I (SRD5A1) homologous sequences on human chromosomes 6 and 8.

scientific article

Nonalcoholic Fatty liver disease: focus on lipoprotein and lipid deregulation

scientific article published on 2 July 2011

Novel cholesterol biosynthesis inhibitors targeting human lanosterol 14alpha-demethylase (CYP51).

scientific article published on 4 October 2007

Novel insights into the downstream pathways and targets controlled by transcription factors CREM in the testis

scientific article

Obesity resistant mechanisms in the Lean polygenic mouse model as indicated by liver transcriptome and expression of selected genes in skeletal muscle

scientific article

Polymorphisms of CYP51A1 from cholesterol synthesis: associations with birth weight and maternal lipid levels and impact on CYP51 protein structure.

scientific article

Pre-cholesterol precursors in gametogenesis

scientific article

Progesterone metabolism by the filamentous fungus Cochliobolus lunatus

scientific article published on 01 May 1994

Regulation of hepatic cytochromes p450 by lipids and cholesterol.

scientific article published on February 2011

Sex differences in the hepatic cholesterol sensing mechanisms in mice.

scientific article published on 10 September 2013

Steroidal triterpenes of cholesterol synthesis.

scientific article published on 04 April 2013

Sterols in spermatogenesis and sperm maturation.

scientific article

Structure and mapping of the human lanosterol 14alpha-demethylase gene (CYP51) encoding the cytochrome P450 involved in cholesterol biosynthesis; comparison of exon/intron organization with other mammalian and fungal CYP genes

scientific article published in December 1996

TNF-alpha interferes with lipid homeostasis and activates acute and proatherogenic processes

scientific article published on 12 June 2007

The Interplay between Circadian System, Cholesterol Synthesis, and Steroidogenesis Affects Various Aspects of Female Reproduction

scientific article

The Sterolgene v0 cDNA microarray: a systemic approach to studies of cholesterol homeostasis and drug metabolism.

scientific article

The human primary hepatocyte transcriptome reveals novel insights into atorvastatin and rosuvastatin action

scientific article published in November 2011

The impact of a new emotional self-management program on stress, emotions, heart rate variability, DHEA and cortisol

scientific article published in April 1998

The interplay of cis-regulatory elements rules circadian rhythms in mouse liver

scientific article

The three human cytochrome P450 lanosterol 14 alpha-demethylase (CYP51) genes reside on chromosomes 3, 7, and 13: structure of the two retrotransposed pseudogenes, association with a line-1 element, and evolution of the human CYP51 family

scientific article published in September 1996

The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha-demethylase, a cytochrome P450 whose expression is regulated by oxysterols.

scientific article published on May 1996

Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis

scientific article published on 01 February 2019

Timing of circadian genes in mammalian tissues.

scientific article published on 22 July 2014

Transcriptional activation of PPARalpha by phenobarbital in the absence of CAR and PXR.

scientific article published in September 2009

Transformation of Cochliobolus lunatus with pUT 720 changes the steroid hydroxylating ability of the fungus

scientific article

Paulina is supported by:

About Paulina

Help