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List of works by John-Stephen Taylor

1H NMR assignment and melting temperature study of cis-syn and trans-syn thymine dimer containing duplexes of d(CGTATTATGC).d(GCATAATACG).

scientific article published in September 1990

A Simple and Efficient Synthesis of an Acid-labile Polyphosphoramidate by Organobase-catalyzed Ring-Opening Polymerization and Transformation to Polyphosphoester Ionomers by Acid Treatment

scientific article published on July 2013

A high-throughput and quantitative method to assess the mutagenic potential of translesion DNA synthesis

scientific article published on 6 March 2013

A method for quantification from composite spectra: application to the determination of isomeric DNA photoproducts by tandem mass spectrometry

scientific article published on 01 January 2001

A new photoproduct of 5-methylcytosine and adenine characterized by high-performance liquid chromatography and mass spectrometry

scientific article

Ability of polymerase eta and T7 DNA polymerase to bypass bulge structures.

scientific article published on 15 February 2007

Acceleration of 5-methylcytosine deamination in cyclobutane dimers by G and its implications for UV-induced C-to-T mutation hotspots

scientific article published on 22 July 2009

Antisense peptide nucleic acid-functionalized cationic nanocomplex for in vivo mRNA detection

scientific article published on June 2013

Benzaldehyde-functionalized polymer vesicles

scientific article published on March 2009

Biomolecules. The dark side of sunlight and melanoma

scientific article published on 01 February 2015

Biotinylated quercetin as an intrinsic photoaffinity proteomics probe for the identification of quercetin target proteins.

scientific article published on 13 July 2011

Bypass of a Site-Specific Cis-Syn Thymine Dimer in an SV40 Vector during in Vitro Replication by HeLa and XPV Cell-Free Extracts ⬇️

scientific article published on June 2, 1998

CEBS--Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data.

scientific article

Caged single and double strand breaks

scientific article published on 01 January 2000

Cationic shell-cross-linked knedel-like (cSCK) nanoparticles for highly efficient PNA delivery

scientific article published on March 2009

Cationic shell-crosslinked knedel-like nanoparticles for highly efficient gene and oligonucleotide transfection of mammalian cells

scientific article published on 26 November 2008

Characterization of a novel cis-syn and trans-syn-II pyrimidine dimer glycosylase/AP lyase from a eukaryotic algal virus, Paramecium bursaria chlorella virus-1.

scientific article published in May 1998

Crystal structure of a DNA decamer containing a cis-syn thymine dimer

scientific article

Cytochrome c biogenesis: mechanisms for covalent modifications and trafficking of heme and for heme-iron redox control.

scientific article published on September 2009

DNA photolyase repairs the trans-syn cyclobutane thymine dimer.

scientific article

DNA polymerase beta-dependent long patch base excision repair in living cells

scientific article

DNA synthesis past a 5-methylC-containing cis-syn-cyclobutane pyrimidine dimer by yeast pol eta is highly nonmutagenic

scientific article published on 01 August 2006

Design, synthesis, and characterization of nucleosomes containing site-specific DNA damage

scientific article

Dual peptide nucleic acid- and peptide-functionalized shell cross-linked nanoparticles designed to target mRNA toward the diagnosis and treatment of acute lung injury

scientific article published on 28 February 2012

Effect of sequence and metal ions on UVB-induced anti cyclobutane pyrimidine dimer formation in human telomeric DNA sequences

scientific article published on 04 March 2014

Efficient protection and transfection of small interfering RNA by cationic shell-crosslinked knedel-like nanoparticles

scientific article

Evidence for Reverse Hoogsteen Hairpin Intermediates in the Photocrosslinking of Human Telomeric DNA Sequences.

scientific article published on 8 February 2018

Evidence for Watson-Crick and not Hoogsteen or wobble base pairing in the selection of nucleotides for insertion opposite pyrimidines and a thymine dimer by yeast DNA pol eta.

scientific article

Evidence that the (6-4) photolyase mechanism can proceed through an oxetane intermediate

scientific article published on 3 September 2008

Fragmentation of electrospray-produced oligodeoxynucleotide ions adducted to metal ions

scientific article

Fragmentation of photomodified oligodeoxynucleotides adducted with metal ions in an electrospray-ionization ion-trap mass spectrometer

scientific article published in November 2001

Identification and structure determination of a third cyclobutane photodimer of thymidylyl-(3'-->5')-thymidine: the trans-syn-II product

scientific article published on 01 July 1993

Identification of critical residues for the tight binding of both correct and incorrect nucleotides to human DNA polymerase λ

scientific article

Imaging mRNA Expression in Live Cells via PNA·DNA Strand Displacement-Activated Probes

scientific article

Imaging mRNA expression levels in living cells with PNA·DNA binary FRET probes delivered by cationic shell-crosslinked nanoparticles

scientific article published on 28 March 2013

Improved nucleic acid triggered probe activation through the use of a 5-thiomethyluracil peptide nucleic acid building block.

scientific article

In vitro evidence that UV-induced frameshift and substitution mutations at T tracts are the result of misalignment-mediated replication past a specific thymine dimer.

scientific article published in April 1992

In vivo evidence that UV-induced C-->T mutations at dipyrimidine sites could result from the replicative bypass of cis-syn cyclobutane dimers or their deamination products

scientific article published on 01 January 1993

Inhibition of heat shock induction of heat shock protein 70 and enhancement of heat shock protein 27 phosphorylation by quercetin derivatives

scientific article published on April 2009

Inhibition of heat shock transcription factor binding by a linear polyamide binding in an unusual 1:1 mode

scientific article published on December 2011

Inhibition of telomerase activity enhances hyperthermia-mediated radiosensitization

scientific article published on 01 May 2008

Lesion bypass activities of human DNA polymerase mu.

scientific article published on 12 September 2002

Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase

scientific article published on 7 October 2006

Methyl CpG binding protein 2 (MeCP2) enhances photodimer formation at methyl-CpG sites but suppresses dimer deamination.

scientific article

Models for the solution state structure of the (6-4) photoproduct of thymidylyl-(3'----5')-thymidine derived via a distance- and angle-constrained conformation search procedure

scientific article published on 01 October 1988

Modulation of cyclobutane thymine photodimer formation in T11-tracts in rotationally phased nucleosome core particles and DNA minicircles

scientific article

Native mRNA antisense-accessible sites library for the selection of antisense oligonucleotides, PNAs, and siRNAs

scientific article

Nucleic Acid-directed Self-assembly of Multifunctional Gold Nanoparticle Imaging Agents.

scientific article

Nucleic acid triggered catalytic drug and probe release: a new concept for the design of chemotherapeutic and diagnostic agents

scientific article published on 01 September 2001

Nucleic acid-triggered fluorescent probe activation by the Staudinger reaction

scientific article published in December 2004

Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.

scientific article published on 4 July 2004

Phospholipid conjugate for intracellular delivery of peptide nucleic acids

scientific article published on September 2009

Photocrosslinking of G-Quadruplex-Forming Sequences found in Human Promoters

scientific article published on 26 September 2018

Phototriggered formation and repair of DNA containing a site-specific single strand break of the type produced by ionizing radiation or AP lyase activity

scientific article published on 01 January 2001

Polyphosphoester-based cationic nanoparticles serendipitously release integral biologically-active components to serve as novel degradable inducible nitric oxide synthase inhibitors

scientific article

Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta.

scientific article

Preparation and characterization of DNA containing a site-specific nonadjacent cyclobutane thymine dimer of the type implicated in UV-induced -1 frameshift mutagenesis

scientific article published on 01 October 1999

Preparation and characterization of a deoxyoligonucleotide 49-mer containing a site-specific thymidylyl-(3',5')-deoxyadenosine photoproduct

scientific article published on 01 January 1995

Preparation of site-specific T=mCG cis-syn cyclobutane dimer-containing template and its error-free bypass by yeast and human polymerase η

scientific article published on 18 January 2012

Quantitative conversion of the (6-4) photoproduct of TpdC to its Dewar valence isomer upon exposure to simulated sunlight

scientific article published on 01 February 1990

Rapid deamination of cyclobutane pyrimidine dimer photoproducts at TCG sites in a translationally and rotationally positioned nucleosome in vivo.

scientific article

Reaction mechanism of (6-4) photolyase

scientific article published in December 1997

Role of base stacking and sequence context in the inhibition of yeast DNA polymerase eta by pyrene nucleotide.

scientific article

Roles of free radicals in type 1 phototherapeutic agents: aromatic amines, sulfenamides, and sulfenates.

scientific article published on 24 June 2013

Rotational position of a 5-methylcytosine-containing cyclobutane pyrimidine dimer in a nucleosome greatly affects its deamination rate.

scientific article

Serial analysis of mutation spectra (SAMS): a new approach for the determination of mutation spectra of site-specific DNA damage and their sequence dependence

scientific article

Shape effects of nanoparticles conjugated with cell-penetrating peptides (HIV Tat PTD) on CHO cell uptake

scientific article

Solid Phase-Supported Thymine Dimers for the Construction of Dimer-Containing DNA by Combined Chemical and Enzymatic Synthesis: A Potentially General Method for the Efficient Incorporation of Modified Nucleotides into DNA ⬇️

scientific article published on October 1, 1997

Solution-state structure of a DNA dodecamer duplex containing a Cis-Syn thymine cyclobutane dimer, the major UV photoproduct of DNA ⬇️

scientific article published on October 9, 1998

Specificity of DNA lesion bypass by the yeast DNA polymerase eta.

scientific article

Structure and fragmentation mechanisms of isomeric T-rich oligodeoxynucleotides: a comparison of four tandem mass spectrometric methods.

scientific article

Structure determination of an interstrand-type cis-anti cyclobutane thymine dimer produced in high yield by UVB light in an oligodeoxynucleotide at acidic pH.

scientific article published on 5 August 2008

Structure-activity relationships of cationic shell-crosslinked knedel-like nanoparticles: shell composition and transfection efficiency/cytotoxicity

scientific article

Synergistic modulation of cyclobutane pyrimidine dimer photoproduct formation and deamination at a TmCG site over a full helical DNA turn in a nucleosome core particle.

scientific article

Synthesis of a trans-syn thymine dimer building block. Solid phase synthesis of CGTAT[t,s]TATGC.

scientific article

Template-directed photoligation of oligodeoxyribonucleotides via 4-thiothymidine

scientific article

The ability of a variety of polymerases to synthesize past site-specific cis-syn, trans-syn-II, (6-4), and Dewar photoproducts of thymidylyl-(3'-->5')-thymidine

scientific article

The trans-syn-I thymine dimer bends DNA by approximately 22 degrees and unwinds DNA by approximately 15 degrees

scientific article published on 01 July 1993

Thermodynamic and base-pairing studies of matched and mismatched DNA dodecamer duplexes containing cis-syn, (6-4) and Dewar photoproducts of TT ⬇️

scientific article published on August 15, 1998

Use of a combined enzymatic digestion/ESI mass spectrometry assay to study the effect of TATA-binding protein on photoproduct formation in a TATA box.

scientific article published in October 2001

Use of multiple carboxylates to increase intracellular retention of fluorescent probes following release from cell penetrating fluorogenic conjugates

scientific article published on 20 November 2007

cis-syn thymine dimers are not absolute blocks to replication by DNA polymerase I of Escherichia coli in vitro.

scientific article published in February 1990

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