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List of works by Dong Guo

5′-Substituted Amiloride Derivatives as Allosteric Modulators Binding in the Sodium Ion Pocket of the Adenosine A2A Receptor

scientific article published on 10 May 2016

A two-state model for the kinetics of competitive radioligand binding

scientific article published on 27 February 2018

Agonists for the adenosine A1 receptor with tunable residence time. A Case for nonribose 4-amino-6-aryl-5-cyano-2-thiopyrimidines

scientific article published on 3 April 2014

Biased and constitutive signaling in the CC-chemokine receptor CCR5 by manipulating the interface between transmembrane helices 6 and 7.

scientific article published on 14 March 2013

Binding kinetics of ZM241385 derivatives at the human adenosine A2A receptor

scientific article published on 3 March 2014

Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength

scientific article

Drug-Target Association Kinetics in Drug Discovery

scientific article published on 14 May 2019

Drug-target residence time--a case for G protein-coupled receptors

scientific article published on 18 February 2014

Dual-point competition association assay: a fast and high-throughput kinetic screening method for assessing ligand-receptor binding kinetics

scientific article

Equilibrium and kinetic selectivity profiling on the human adenosine receptors

scientific article

Exploring chemical substructures essential for HERG k(+) channel blockade by synthesis and biological evaluation of dofetilide analogues

scientific article

Functional efficacy of adenosine A₂A receptor agonists is positively correlated to their receptor residence time

scientific article published on July 2012

GPCR structure and activation: an essential role for the first extracellular loop in activating the adenosine A2B receptor

scholarly article published February 2011

Gating function of isoleucine-116 in TM-3 (position III:16/3.40) for the activity state of the CC-chemokine receptor 5 (CCR5).

scientific article

Kinetic Aspects of the Interaction between Ligand and G Protein-Coupled Receptor: The Case of the Adenosine Receptors

scientific article published on 18 April 2016

Mass spectrometry-based ligand binding assays on adenosine A1 and A2A receptors.

scientific article

Molecular Basis of Ligand Dissociation from the Adenosine A2A Receptor

scientific article published on 12 February 2016

Molecular mechanism of allosteric modulation at GPCRs: insight from a binding kinetics study at the human A1 adenosine receptor

scientific article published on 5 September 2014

Structure-Activity Relationships of the Sustained Effects of Adenosine A2A Receptor Agonists Driven by Slow Dissociation Kinetics.

scientific article published on November 2016

Structure-kinetics relationships of Capadenoson derivatives as adenosine A 1 receptor agonists

scientific article published on 15 July 2015

The Added Value of Assessing Ligand-Receptor Binding Kinetics in Drug Discovery

scientific article published on 19 August 2016

The Role of Target Binding Kinetics in Drug Discovery

scientific article published on 25 August 2015

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