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List of works by Philippe Pasero

A 'DNA replication' signature of progression and negative outcome in colorectal cancer

scientific article published on 9 November 2009

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy

scientific article

A journey into the nucleus. Conference on Nuclear Structure and Dynamics

scientific article published on 15 February 2008

A role for the Cdc7 kinase regulatory subunit Dbf4p in the formation of initiation-competent origins of replication

scientific article

An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing

scientific article

An essential role for Orc6 in DNA replication through maintenance of pre-replicative complexes

scientific article

Analysis of DNA replication profiles in budding yeast and mammalian cells using DNA combing.

scientific article published on 03 May 2012

Analysis of replication profiles reveals key role of RFC-Ctf18 in yeast replication stress response

scientific article published on 24 October 2010

Anaphase Onset Before Complete DNA Replication with Intact Checkpoint Responses

scientific article published in Science

Caught in the Act: R-Loops Are Cleaved by Structure-Specific Endonucleases to Generate DSBs

Closing the MCM cycle at replication termination sites

scientific article published on 12 November 2014

Cohesin association to replication sites depends on rad50 and promotes fork restart

scientific article published on 09 August 2012

Common DNA structural features exhibited by eukaryotic ribosomal gene promoters.

scientific article published on June 1996

Cyclin B-cdk1 kinase stimulates ORC- and Cdc6-independent steps of semiconservative plasmid replication in yeast nuclear extracts

scientific article

DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling

DDK has a primary role in processing stalled replication forks to initiate downstream checkpoint signaling

DDR Inc., one business, two associates

scientific article published on 22 November 2018

DNA polymerase η modulates replication fork progression and DNA damage responses in platinum-treated human cells

scientific article published on 20 November 2013

DNA repair in diffuse large B-cell lymphoma: a molecular portrait

scientific article published on 05 November 2014

DNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment

scientific article published on 09 August 2013

DNA replication stress response involving PLK1, CDC6, POLQ, RAD51 and CLASPIN upregulation prognoses the outcome of early/mid-stage non-small cell lung cancer patients.

scientific article

Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing

scientific article published on 12 January 2018

Defining replication origin efficiency using DNA fiber assays

scientific article published on January 2010

Differential regulation of homologous recombination at DNA breaks and replication forks by the Mrc1 branch of the S-phase checkpoint

scientific article published on 26 March 2009

Does interference between replication and transcription contribute to genomic instability in cancer cells?

scientific article published on 15 May 2010

Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression

scientific article

Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance

scientific article published on 19 November 2015

Ethanol exposure increases mutation rate through error-prone polymerases

scientific article published on 21 July 2020

Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation.

scientific article

Genetic and epigenetic determinants of DNA replication origins, position and activation

scientific article published on 28 March 2013

Histone H3 lysine 56 acetylation and the response to DNA replication fork damage

scientific article

Homologous recombination and Mus81 promote replication completion in response to replication fork blockage

scientific article published on 17 May 2020

In Vitro DNA Replication in Yeast Nuclear Extracts

scientific article published on 01 July 1999

In vitro DNA replication assays in yeast extracts

scientific article

Interference between DNA replication and transcription as a cause of genomic instability

scientific article published on March 2012

Involvement of a chromatin remodeling complex in damage tolerance during DNA replication

scientific article

MRX Increases Chromatin Accessibility at Stalled Replication Forks to Promote Nascent DNA Resection and Cohesin Loading

scientific article published on 20 November 2019

Maintenance of fork integrity at damaged DNA and natural pause sites

scientific article published on 26 March 2007

Mec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication

scientific article published on 04 March 2020

Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress

scientific article published on 21 January 2016

Mitotic remodeling of the replicon and chromosome structure

scientific article published in December 2005

Molecular dissection of a specific nuclear domain: the chromatin region of the ribosomal gene cluster in Xenopus laevis

scientific article published in September 1992

Monitoring S phase progression globally and locally using BrdU incorporation in TK(+) yeast strains.

scientific article published on April 2001

Mrc1 and Rad9 cooperate to regulate initiation and elongation of DNA replication in response to DNA damage

scholarly article by Julien Bacal published in November 2018

Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53.

scientific article

Multiple roles of replication forks in S phase checkpoints: sensors, effectors and targets.

scientific article published on November 2003

New Topoisomerase I mutations are associated with resistance to camptothecin

scientific article published on 27 May 2011

New histone supply regulates replication fork speed and PCNA unloading

scientific article published on 30 December 2013

New systems for replicating DNA in vitro ⬇️

scientific article published on 01 June 1998

Nuclear DNA replication and repair in parasites of the genus Leishmania: Exploiting differences to develop innovative therapeutic approaches

scientific article published on 14 December 2016

Nucleases Acting at Stalled Forks: How to Reboot the Replication Program with a Few Shortcuts

scientific article published in November 2017

Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing

scientific article published on 17 March 2013

ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase

scientific article published on December 2002

ORC-dependent and origin-specific initiation of DNA replication at defined foci in isolated yeast nuclei

scientific article published on 01 June 1997

Overexpression of the Fork Protection Complex: a strategy to tolerate oncogene-induced replication stress in cancer cells

scientific article published on 07 May 2019

Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest

scientific article published on 13 June 2016

Phosphorylation of Slx4 by Mec1 and Tel1 regulates the single-strand annealing mode of DNA repair in budding yeast

scientific article published on 16 July 2007

RECQ helicases are deregulated in hematological malignancies in association with a prognostic value

scientific article published on 13 February 2016

RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma

scientific article

RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells

scientific article

RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together

scientific article

Rescuing stalled or damaged replication forks

scientific article

Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA

scientific article

SAMHD1 acts at stalled replication forks to prevent interferon induction

scientific article published in Nature

SAMHD1 and the innate immune response to cytosolic DNA during DNA replication

scholarly article by Flavie Coquel et al published February 2019 in Current Opinion in Immunology

SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage.

scientific article

Semi-conservative replication in yeast nuclear extracts requires Dna2 helicase and supercoiled template.

scientific article

Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

scientific article published on 7 February 2018

Short DNA fragments without sequence similarity are initiation sites for replication in the chromosome of the yeast Yarrowia lipolytica

scientific article published on March 1999

Signaling pathways of replication stress in yeast

scientific article published on 2 December 2016

Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locus

scientific article

Sir2 takes affirmative action to ensure equal opportunity in replication origin licensing

scientific article published on 30 June 2020

Size variation of rDNA clusters in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe

scientific article published in January 1993

Specific function of phosphoinositide 3-kinase beta in the control of DNA replication

scholarly article

The Cullin Rtt101p Promotes Replication Fork Progression through Damaged DNA and Natural Pause Sites

scientific article published on 01 April 2006

The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress

scientific article published on 12 March 2009

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages

scientific article published on 22 June 2010

The causes of replication stress and their consequences on genome stability and cell fate.

scientific article

The histone deacetylases sir2 and rpd3 act on ribosomal DNA to control the replication program in budding yeast

scientific article

The replication timing program in the hands of two HDACs

scientific article published on 25 July 2014

The yeast Sgs1 helicase is differentially required for genomic and ribosomal DNA replication

scientific article

Think global, act local--how to regulate S phase from individual replication origins.

scientific article

Time to be versatile: regulation of the replication timing program in budding yeast

scientific article published on 25 September 2013

Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites

scientific article published on 07 August 2020

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

scientific article

Transcription and replication: breaking the rules of the road causes genomic instability

scientific article published on September 2010

Transcription-Replication Conflicts: Orientation Matters

scientific article published on 01 August 2017

USP1 Regulates Cellular Senescence by Controlling Genomic Integrity

scientific article published on 4 May 2016

Upregulation of error-prone DNA polymerases beta and kappa slows down fork progression without activating the replication checkpoint

scientific article published on 19 February 2007

dNTP pools determine fork progression and origin usage under replication stress

scientific article published on 10 January 2012

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