List of works - Pascal Ferré

A new role for a metabolic star: AMP-activated protein kinase stimulates fat absorption

scientific article published on 01 January 2011

AMP-activated protein kinase activation modulates progesterone secretion in granulosa cells from hen preovulatory follicles.

scientific article

AMP-activated protein kinase inhibits the glucose-activated expression of fatty acid synthase gene in rat hepatocytes

scientific article published in June 1998

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

scientific article

Action and secretion of insulin: a dual role for potassium channels

scientific article

Activation of AMPK-Regulated CRH Neurons in the PVH is Sufficient and Necessary to Induce Dietary Preference for Carbohydrate over Fat.

scientific article published in January 2018

Adenosine 5'-monophosphate-activated protein kinase regulates progesterone secretion in rat granulosa cells

scientific article published on 14 July 2005

Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice.

scientific article published in November 2001

Adipocyte functions are modulated by cell size change: potential involvement of an integrin/ERK signalling pathway

scientific article published on 01 October 2003

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

scientific article

Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes

scientific journal article

Biguanides and thiazolidinediones inhibit stimulated lipolysis in human adipocytes through activation of AMP-activated protein kinase

scientific article published on 31 December 2009

Ceramide Transporter CERT Is Involved in Muscle Insulin Signaling Defects Under Lipotoxic Conditions

scientific article published on 14 May 2018

Characterising the inhibitory actions of ceramide upon insulin signaling in different skeletal muscle cell models: a mechanistic insight

scientific article

Cholesterol, a cell size-dependent signal that regulates glucose metabolism and gene expression in adipocytes

scientific article published on 27 February 2001

Cholesterol-induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis

scientific article published on May 2006

Control of hepatic mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase during the foetal/neonatal transition, suckling and weaning in the rat

scientific article published on 01 January 1991

Correction: Glucocorticoids Inhibit Basal and Hormone-Induced Serotonin Synthesis in Pancreatic Beta Cells

scientific article

Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance

scientific article published in April 2005

Depolarizing actions of GABA in immature neurons depend neither on ketone bodies nor on pyruvate.

scientific article

Development of obesity in Zucker rats. Early insulin resistance in muscles but normal sensitivity in white adipose tissue

scholarly article by L. Penicaud et al published 1 May 1987 in Diabetes

Diabetes and inflammation: fundamental aspects and clinical implications.

scientific article published on 18 September 2010

Differential regulation of sterol regulatory element-binding protein 1c transcriptional activity by insulin and liver X receptor during liver development

scientific article published on 27 October 2004

Discrete brain areas express the insulin-responsive glucose transporter GLUT4

scientific article published on 01 May 1996

Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c

scientific journal article

DnaJA4 is a SREBP-regulated chaperone involved in the cholesterol biosynthesis pathway

scientific article published on 26 July 2006

Effect of acarbose on glucose homeostasis, lipogenesis and lipogenic enzyme gene expression in adipose tissue of weaned rats.

scientific article published on June 1993

Effect of diets rich in medium-chain and long-chain triglycerides on lipogenic-enzyme gene expression in liver and adipose tissue of the weaned rat

scientific article published on 01 September 1992

Effect of feeding pattern on the sensitivity of hepatic carnitine palmitoyl-transferase to inhibition by malonyl-CoA in the rat.

scientific article published in January 1987

Effect of insulin on the properties of liver carnitine palmitoyltransferase in the starved rat: assessment by the euglycemic hyperinsulinemic clamp

scientific article published on 01 August 1991

Effects of Medium-Chain Triglycerides (M.C.T)in the starved newborn rat

article published in 1981

Effects of insulin and norepinephrine on glucose transport and metabolism in rat brown adipocytes. Potentiation by insulin of norepinephrine-induced glucose oxidation

scientific article published on 01 December 1987

Effects of prolonged physical exercise and fasting upon plasma testosterone level in rats.

scientific article published in January 1982

Emerging topics in type 2 diabetes: new mechanisms leading to new treatments?

scientific article published on 05 November 2009

Endoplasmic reticulum stress: a new actor in the development of hepatic steatosis.

scientific article published on June 2010

Evidence for the presence of several phosphodiesterase isoforms in brown adipose tissue of Zucker rats: modulation of PDE2 by the fa gene expression

scientific article published on 01 July 1999

Evidence that the development of hepatic fatty acid oxidation at birth in the rat is concomitant with an increased intramitochondrial CoA concentration

scientific article published on 01 May 1986

Extracellular adenosine activates AMP-dependent protein kinase (AMPK).

scientific article published on 28 March 2006

Facilitative glucose transporters in ruminants.

scientific article published on March 1996

Fetal PGC-1α overexpression programs adult pancreatic β-cell dysfunction

scientific article published on 28 December 2012

Functions of AMP-activated protein kinase in adipose tissue.

scientific article

GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice

scientific article published on 13 April 2009

Genetics and the pathophysiology of obesity

scientific article

Glucocorticoids Inhibit Basal and Hormone-Induced Serotonin Synthesis in Pancreatic Beta Cells

scientific article

Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver

scientific article published on 09 August 2011

Glucose transporter 2 (GLUT 2): expression in specific brain nuclei.

scientific article

Glucose utilization rates and insulin sensitivity in vivo in tissues of virgin and pregnant rats

Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression

scientific article published on 25 February 2004

Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c

scientific article

High carbohydrate diet induces nonalcoholic steato-hepatitis (NASH) in a desert gerbil.

scientific article

Hypoglycemic effects of a beta-agonist, Ro 16-8714, in streptozotocin-diabetic rats: decreased hepatic glucose production and increased glucose utilization in oxidative muscles

scientific article published on 01 February 1992

Impaired beta-adrenergic signaling pathway in white adipocytes of suckling fa/fa Zucker rats: a defect in receptor coupling

scientific article published on 01 November 2001

Impaired hepatic glycogenolysis related to hyperinsulinemia in newborns from hyperglycemic pregnant rats

scientific article published on 01 December 1990

Increased mitogen-activated protein kinase expression and activity in white adipose tissue of ventromedial hypothalamus-lesioned rats.

scientific article published on May 1997

Influence of diet on the development and regulation of lipogenic enzymes in adipose tissue.

scientific article published on December 1992

Influence of exogenous cortisol and triglyceride feeding on glucose homeostasis in the fasted newborn rat.

scientific article published in July 1978

Insulin and angiotensin II induce the translocation of scavenger receptor class B, type I from intracellular sites to the plasma membrane of adipocytes

scientific article

Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes.

scientific article published in September 2000

Insulin signaling and insulin resistance

scientific article published in July 2007

Insulin-sensitive glucose transporter transcript levels in calf muscles assessed with a bovine GLUT4 cDNA fragment

scientific article published in July 1996

Intramitochondrial factors controlling hepatic fatty acid oxidation at weaning in the rat

scientific article published on 01 May 1988

Isoproterenol inhibits insulin-stimulated tyrosine phosphorylation of the insulin receptor without increasing its serine/threonine phosphorylation

scientific article published on 01 November 1995

Ketone body transport in the human neonate and infant.

scientific article

Ketosis-prone type 2 diabetes mellitus and human herpesvirus 8 infection in sub-saharan africans.

scientific article published on June 2008

Kidney Dysfunction in Adult Offspring Exposed In Utero to Type 1 Diabetes Is Associated with Alterations in Genome-Wide DNA Methylation

scientific article published on 10 August 2015

Laforin, a dual specificity phosphatase involved in Lafora disease, regulates insulin response and whole-body energy balance in mice.

scientific article published on 14 April 2011

Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects.

scientific article

Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes

scientific article

Liver X receptor: from metabolism to cancer

scientific article published on 01 April 2014

Long chain fatty acyl-CoA synthetase 5 expression is induced by insulin and glucose: involvement of sterol regulatory element-binding protein-1c

scientific journal article

Mechanisms by which carbohydrates regulate expression of genes for glycolytic and lipogenic enzymes.

scientific article

Metabolic Interactions between Hepatic Fatty Acid Oxidation and Gluconeogenesis in the Newborn Rat ⬇️

scientific article published on January 1, 1978

Metabolic effects of testosterone during prolonged physical exercise and fasting.

scientific article published in January 1984

Metformin-induced stimulation of adenosine 5' monophosphate-activated protein kinase (PRKA) impairs progesterone secretion in rat granulosa cells

scientific journal article

Molecular and cellular mechanisms of adipose secretion: comparison of leptin and angiotensinogen

scientific article

Molecular and metabolic changes in white adipose tissue of the rat during development of ventromedial hypothalamic obesity

scientific article published in July 1992

New insights into ER stress-induced insulin resistance.

scientific article published on 04 July 2012

New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c

scientific article

Normal insulin sensitivity during the phase of glucose intolerance but insulin resistance at the onset of diabetes in the spontaneously diabetic BB rat.

scientific article

Novel insights in the interplay between inflammation and metabolic diseases: a role for the pathogen sensing kinase PKR

scientific article published on 17 February 2011

Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).

scientific article

PPARγ contributes to PKM2 and HK2 expression in fatty liver

scientific article published on 14 February 2012

Pioglitazone-induced increase of insulin sensitivity in the muscles of the obese Zucker fa/fa rat cannot be explained by local adipocyte differentiation

scientific article published in August 1998

Plasma membrane subdomain compartmentalization contributes to distinct mechanisms of ceramide action on insulin signaling

scientific article

Polyunsaturated fatty acids inhibit fatty acid synthase and spot-14-protein gene expression in cultured rat hepatocytes by a peroxidative mechanism.

scientific article published on July 1999

Prevention of adipose tissue depletion during food deprivation in angiotensin type 2 receptor-deficient mice

scientific article published on 3 August 2006

Progesterone stimulates adipocyte determination and differentiation 1/sterol regulatory element-binding protein 1c gene expression. potential mechanism for the lipogenic effect of progesterone in adipose tissue

scientific journal article

Regulation of ABCA1 expression and cholesterol efflux during adipose differentiation of 3T3-L1 cells

scientific article published on 16 May 2003

Regulation of lipogenic enzyme and phosphoenolpyruvate carboxykinase gene expression in cultured white adipose tissue. Glucose and insulin effects are antagonized by cAMP.

scientific article

SREBF-1 gene polymorphisms are associated with obesity and type 2 diabetes in French obese and diabetic cohorts

scientific article published on 01 August 2004

SREBP transcription factors: master regulators of lipid homeostasis

scientific article

SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma

scientific article

SREBP-1c transcription factor and lipid homeostasis: clinical perspective

scientific article

Short Term Palmitate Supply Impairs Intestinal Insulin Signaling via Ceramide Production

scientific article published on 2 June 2016

Specific increase in leptin production in obese (falfa) rat adipose cells

scientific journal article

Steatosis and NASH in type 2 diabetes.

scientific article published on 30 October 2017

Sterol regulatory element binding protein-1c expression and action in rat muscles: insulin-like effects on the control of glycolytic and lipogenic enzymes and UCP3 gene expression

scientific article published in June 2002

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

scientific article

Sterol regulatory element-binding protein-1c mimics the negative effect of insulin on phosphoenolpyruvate carboxykinase (GTP) gene transcription

article

Stimulation of acetyl-CoA carboxylase gene expression by glucose requires insulin release and sterol regulatory element binding protein 1c in pancreatic MIN6 beta-cells

scientific article published on August 2002

Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE

scientific article

The acute phase protein Serum Amyloid A induces lipolysis and inflammation in human adipocytes through distinct pathways

scientific article

The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity

scientific article (publication date: February 2004)

The inhibitory effect of glucose on phosphoenolpyruvate carboxykinase gene expression in cultured hepatocytes is transcriptional and requires glucose metabolism

scientific article published on 01 November 1999

Vitamin A, in the eye of the fat

scientific article published in November 2007

Weaning marginally affects glucose transporter (GLUT4) expression in calf muscles and adipose tissues ⬇️

scientific article published on August 1, 1997

[A new role for insulin in the control of energetic metabolism in liver]

scientific article published on 01 June 2005

[Cheers !]

scientific article published on 01 February 2007

[To lose weight, let us make bile]

scientific article published on 01 April 2006

[Unfolded protein response: its role in physiology and physiopathology]

scientific article published on 01 March 2007

List of works by Pascal Ferré

A new role for a metabolic star: AMP-activated protein kinase stimulates fat absorption

AMP-activated protein kinase activation modulates progesterone secretion in granulosa cells from hen preovulatory follicles.

AMP-activated protein kinase inhibits the glucose-activated expression of fatty acid synthase gene in rat hepatocytes

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

Action and secretion of insulin: a dual role for potassium channels

Activation of AMPK-Regulated CRH Neurons in the PVH is Sufficient and Necessary to Induce Dietary Preference for Carbohydrate over Fat.

Adenosine 5'-monophosphate-activated protein kinase regulates progesterone secretion in rat granulosa cells

Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice.

Adipocyte functions are modulated by cell size change: potential involvement of an integrin/ERK signalling pathway

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes

Biguanides and thiazolidinediones inhibit stimulated lipolysis in human adipocytes through activation of AMP-activated protein kinase

Ceramide Transporter CERT Is Involved in Muscle Insulin Signaling Defects Under Lipotoxic Conditions

Characterising the inhibitory actions of ceramide upon insulin signaling in different skeletal muscle cell models: a mechanistic insight

Cholesterol, a cell size-dependent signal that regulates glucose metabolism and gene expression in adipocytes

Cholesterol-induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis

Control of hepatic mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase during the foetal/neonatal transition, suckling and weaning in the rat

Correction: Glucocorticoids Inhibit Basal and Hormone-Induced Serotonin Synthesis in Pancreatic Beta Cells

Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance

Depolarizing actions of GABA in immature neurons depend neither on ketone bodies nor on pyruvate.

Development of obesity in Zucker rats. Early insulin resistance in muscles but normal sensitivity in white adipose tissue

Diabetes and inflammation: fundamental aspects and clinical implications.

Differential regulation of sterol regulatory element-binding protein 1c transcriptional activity by insulin and liver X receptor during liver development

Discrete brain areas express the insulin-responsive glucose transporter GLUT4

Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c

DnaJA4 is a SREBP-regulated chaperone involved in the cholesterol biosynthesis pathway

Effect of acarbose on glucose homeostasis, lipogenesis and lipogenic enzyme gene expression in adipose tissue of weaned rats.

Effect of diets rich in medium-chain and long-chain triglycerides on lipogenic-enzyme gene expression in liver and adipose tissue of the weaned rat

Effect of feeding pattern on the sensitivity of hepatic carnitine palmitoyl-transferase to inhibition by malonyl-CoA in the rat.

Effect of insulin on the properties of liver carnitine palmitoyltransferase in the starved rat: assessment by the euglycemic hyperinsulinemic clamp

Effects of Medium-Chain Triglycerides (M.C.T)in the starved newborn rat

Effects of insulin and norepinephrine on glucose transport and metabolism in rat brown adipocytes. Potentiation by insulin of norepinephrine-induced glucose oxidation

Effects of prolonged physical exercise and fasting upon plasma testosterone level in rats.

Emerging topics in type 2 diabetes: new mechanisms leading to new treatments?

Endoplasmic reticulum stress: a new actor in the development of hepatic steatosis.

Evidence for the presence of several phosphodiesterase isoforms in brown adipose tissue of Zucker rats: modulation of PDE2 by the fa gene expression

Evidence that the development of hepatic fatty acid oxidation at birth in the rat is concomitant with an increased intramitochondrial CoA concentration

Extracellular adenosine activates AMP-dependent protein kinase (AMPK).

Facilitative glucose transporters in ruminants.

Fetal PGC-1α overexpression programs adult pancreatic β-cell dysfunction

Functions of AMP-activated protein kinase in adipose tissue.

GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice

Genetics and the pathophysiology of obesity

Glucocorticoids Inhibit Basal and Hormone-Induced Serotonin Synthesis in Pancreatic Beta Cells

Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver

Glucose transporter 2 (GLUT 2): expression in specific brain nuclei.

Glucose utilization rates and insulin sensitivity in vivo in tissues of virgin and pregnant rats

Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression

Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c

High carbohydrate diet induces nonalcoholic steato-hepatitis (NASH) in a desert gerbil.

Hypoglycemic effects of a beta-agonist, Ro 16-8714, in streptozotocin-diabetic rats: decreased hepatic glucose production and increased glucose utilization in oxidative muscles

Impaired beta-adrenergic signaling pathway in white adipocytes of suckling fa/fa Zucker rats: a defect in receptor coupling

Impaired hepatic glycogenolysis related to hyperinsulinemia in newborns from hyperglycemic pregnant rats

Increased mitogen-activated protein kinase expression and activity in white adipose tissue of ventromedial hypothalamus-lesioned rats.

Influence of diet on the development and regulation of lipogenic enzymes in adipose tissue.

Influence of exogenous cortisol and triglyceride feeding on glucose homeostasis in the fasted newborn rat.

Insulin and angiotensin II induce the translocation of scavenger receptor class B, type I from intracellular sites to the plasma membrane of adipocytes

Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes.

Insulin signaling and insulin resistance

Insulin-sensitive glucose transporter transcript levels in calf muscles assessed with a bovine GLUT4 cDNA fragment

Intramitochondrial factors controlling hepatic fatty acid oxidation at weaning in the rat

Isoproterenol inhibits insulin-stimulated tyrosine phosphorylation of the insulin receptor without increasing its serine/threonine phosphorylation

Ketone body transport in the human neonate and infant.

Ketosis-prone type 2 diabetes mellitus and human herpesvirus 8 infection in sub-saharan africans.

Kidney Dysfunction in Adult Offspring Exposed In Utero to Type 1 Diabetes Is Associated with Alterations in Genome-Wide DNA Methylation

Laforin, a dual specificity phosphatase involved in Lafora disease, regulates insulin response and whole-body energy balance in mice.

Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects.

Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes

Liver X receptor: from metabolism to cancer

Long chain fatty acyl-CoA synthetase 5 expression is induced by insulin and glucose: involvement of sterol regulatory element-binding protein-1c

Mechanisms by which carbohydrates regulate expression of genes for glycolytic and lipogenic enzymes.

Metabolic Interactions between Hepatic Fatty Acid Oxidation and Gluconeogenesis in the Newborn Rat ⬇️

Metabolic effects of testosterone during prolonged physical exercise and fasting.

Metformin-induced stimulation of adenosine 5' monophosphate-activated protein kinase (PRKA) impairs progesterone secretion in rat granulosa cells

Molecular and cellular mechanisms of adipose secretion: comparison of leptin and angiotensinogen

Molecular and metabolic changes in white adipose tissue of the rat during development of ventromedial hypothalamic obesity

New insights into ER stress-induced insulin resistance.

New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c

Normal insulin sensitivity during the phase of glucose intolerance but insulin resistance at the onset of diabetes in the spontaneously diabetic BB rat.