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List of works by Francisco Abad-Santos

A simple assay for the simultaneous determination of human plasma albendazole and albendazole sulfoxide levels by high performance liquid chromatography in tandem mass spectrometry with solid-phase extraction.

scientific article published on 2 September 2013

ATA homozigosity in the IL-10gene promoter is a risk factor for schizophrenia in Spanish females: a case control study ⬇️

scientific article published on June 9, 2011

Albumin prevents mitochondrial depolarization and apoptosis elicited by endoplasmic reticulum calcium depletion of neuroblastoma cells

scientific article

An eutomer/distomer ratio near unity does not justify non-enantiospecific assay methods in bioequivalence studies.

scientific article published in October 2005

Application of pharmacogenomics and other new technologies to drug development

scientific article

Assessment of sex differences in pharmacokinetics and pharmacodynamics of amlodipine in a bioequivalence study

scientific article

Association between Genetic Polymorphisms and Response to Anti-TNFs in Patients with Inflammatory Bowel Disease

scientific article

Association between psoriasis and polymorphisms in the TNF, IL12B, and IL23R genes in Spanish patients

scientific article published in September 2013

Association of common genetic variants with risperidone adverse events in a Spanish schizophrenic population ⬇️

scientific article published on January 3, 2012

Attention deficit hyperactivity disorder: genetic association study in a cohort of Spanish children

scientific article

Author's Response to: 'Letter to the Editor in Response to: "Effect of Polymorphisms in CYP2C9 and CYP2C19 on the Disposition, Safety and Metabolism of Progesterone Administrated Orally or Vaginally"'

scientific article published on 24 December 2019

CNVs Associated with Different Clinical Phenotypes of Psoriasis and Anti-TNF-Induced Palmoplantar Pustulosis

scientific article published in 2022

CYP2D6 poor metabolizer status might be associated with better response to risperidone treatment

scientific article published in November 2013

Comparison of gastric endoscopic lesions and tolerability to ibuprofen and ibuprofen-arginate in healthy subjects

scientific article

Consumption of Drugs and Nonpharmacological Therapies in Caregivers of Patients with Alzheimer's Disease: A Case-Control Study in Madrid

scientific article published on January 2016

DRD2 Taq1A polymorphism modulates prolactin secretion induced by atypical antipsychotics in healthy volunteers

Digoxin level and clinical manifestations as determinants in the diagnosis of digoxin toxicity

scientific article published on 01 April 2000

Effect of Chondroitin Sulphate on Pro-Inflammatory Mediators and Disease Activity in Patients with Inflammatory Bowel Disease.

scientific article published on 19 September 2015

Effect of Cytochrome P450 and ABCB1 Polymorphisms on Imatinib Pharmacokinetics After Single-Dose Administration to Healthy Subjects

scientific article published on 15 May 2020

Effect of Polymorphisms in CYP2C9 and CYP2C19 on the Disposition, Safety and Metabolism of Progesterone Administrated Orally or Vaginally

scientific article published on 03 September 2019

Effect of Sex, Use of Pantoprazole and Polymorphisms in SLC22A1, ABCB1, CES1, CYP3A5 and CYP2D6 on the Pharmacokinetics and Safety of Dabigatran

scientific article published on 20 June 2020

Effect of Truncating AUC at 12, 24 and 48 hr When Evaluating the Bioequivalence of Drugs with a Long Half-Life.

scientific article published on 18 June 2015

Effect of food on the pharmacokinetics of omeprazole, pantoprazole and rabeprazole

scientific article published on 25 July 2020

Effect of gender and CYP2C9 and CYP2C8 polymorphisms on the pharmacokinetics of ibuprofen enantiomers

scientific article published on 30 June 2015

Effect of ibuprofen on cyclooxygenase and nitric oxide synthase of gastric mucosa: correlation with endoscopic lesions and adverse reactions

scientific article published in September 2004

Effect of polymorphisms on the pharmacokinetics, pharmacodynamics, and safety of risperidone in healthy volunteers

Effect of the Most Relevant CYP3A4 and CYP3A5 Polymorphisms on the Pharmacokinetic Parameters of 10 CYP3A Substrates

scientific article published on 22 April 2020

Effects of CYP2D6 genotype on the pharmacokinetics, pharmacodynamics, and safety of risperidone in healthy volunteers

scientific article published on October 2010

Effects of aripiprazole on pupillometric parameters related to pharmacokinetics and pharmacogenetics after single oral administration to healthy subjects

scientific article published on 25 September 2018

Effects of dotarizine and flunarizine on chromaffin cell viability and cytosolic Ca2+.

scientific article

Epigenetic biomarkers associated with antitumour necrosis factor drug response in moderate-to-severe psoriasis.

scientific article published on 30 March 2017

Evaluating a newly developed pharmacogenetic array: screening in a Spanish population.

scientific article published on November 2010

Evaluation of Voriconazole CYP2C19 Phenotype-Guided Dose Adjustments by Physiologically Based Pharmacokinetic Modeling

scientific article published on 17 September 2020

Evaluation of sex differences in the pharmacokinetics of ranitidine in humans

scientific article published in August 1996

Evaluation of the Relationship Between Pharmacokinetics and the Safety of Aripiprazole and Its Cardiovascular Effects in Healthy Volunteers

scientific article published on 28 September 2016

Evaluation of the relationship between polymorphisms in CYP2C19 and the pharmacokinetics of omeprazole, pantoprazole and rabeprazole

scientific article published in January 2014

Evaluation of the relationship between polymorphisms in CYP2C8 and CYP2C9 and the pharmacokinetics of celecoxib

scientific article

Evaluation of the relationship between sex, polymorphisms in CYP2C8 and CYP2C9, and pharmacokinetics of angiotensin receptor blockers

scientific article published on 01 November 2012

Gender differences in angiotensin-converting enzyme (ACE) activity and inhibition by enalaprilat in healthy volunteers

scientific article published in May 2004

Gene polymorphisms that can predict response to anti-TNF therapy in patients with psoriasis and related autoimmune diseases

scientific article published on 22 January 2013

Genetic variants of interferon-stimulated genes and IL-28B as host prognostic factors of response to combination treatment for chronic hepatitis C.

scientific article published on 12 October 2011

Genetics of psoriasis and pharmacogenetics of biological drugs

scientific article

IL17RA gene variants and anti-TNF response among psoriasis patients.

scientific article published on 27 September 2016

Important Pharmacogenetic Information for Drugs Prescribed During the SARS-CoV-2 Infection (COVID-19)

scientific article published on 16 September 2020

Improvement and validation of a high-performance liquid chromatography in tandem mass spectrometry method for monitoring of omeprazole in plasma

scientific article published in June 2015

In vitro models for the study of nerve lesions and potential neuroprotective drugs

scientific article published on 01 December 1997

Influence of CYP2B6 activity score on the pharmacokinetics and safety of single dose efavirenz in healthy volunteers

scientific article published on 18 October 2019

Influence of CYP2C8 and CYP2C9 polymorphisms on pharmacokinetic and pharmacodynamic parameters of racemic and enantiomeric forms of ibuprofen in healthy volunteers

scientific article published on 23 July 2008

Influence of sex and CYP2D6 genotype on mirtazapine disposition, evaluated in Spanish healthy volunteers

scientific article

Investigation on the Existence of Sex-By-Formulation Interaction in Bioequivalence Trials

scientific article published on 23 July 2019

Involvement of CYP2D6 and CYP2B6 on tramadol pharmacokinetics

scientific article published on 15 June 2020

Meta-analysis of clarithromycin compared to other antibiotics for the treatment of lower respiratory tract infections

scientific article published in December 2003

Meta-analysis of clarithromycin compared with other antimicrobial drugs in the treatment of upper respiratory tract infections

scientific article

Metabolic Effects of Aripiprazole and Olanzapine Multiple-Dose Treatment in a Randomised Crossover Clinical Trial in Healthy Volunteers: Association with Pharmacogenetics

scientific article published on 05 December 2020

New immune system genetic polymorphisms associated with moderate-to-severe plaque psoriasis: a case-control study

scientific article published on 18 March 2015

New polymorphisms associated with response to anti-TNF drugs in patients with moderate-to-severe plaque psoriasis.

scientific article published on 27 September 2016

Nimodipine transfer into human breast milk and cerebrospinal fluid

scientific article published on 01 February 1996

Novel antimigraineur dotarizine releases Ca2+ from caffeine-sensitive Ca2+ stores of chromaffin cells

scientific article published on October 1999

Paradoxical psoriasiform reactions to anti-TNFα drugs are associated with genetic polymorphisms in patients with psoriasis

scientific article published on 21 July 2015

Pharmacodynamic genetic variants related to antipsychotic adverse reactions in healthy volunteers

scientific article published in July 2013

Pharmacogenetic relevance of the CYP2C9*3 allele in a tenoxicam bioequivalence study performed on Spaniards.

scientific article

Pharmacogenetic studies assessment in clinical research: Four issues, four opinions

scientific article published on 17 June 2010

Pharmacogenetics Update on Biologic Therapy in Psoriasis

scientific article published on 20 December 2020

Pharmacogenetics and Pharmacogenomics in Moderate-to-Severe Psoriasis

scientific article published on 18 September 2017

Pharmacogenetics of methylphenidate in childhood attention-deficit/hyperactivity disorder: long-term effects.

scientific article published on 4 September 2017

Pharmacogenetics of quetiapine in healthy volunteers: association with pharmacokinetics, pharmacodynamics, and adverse effects

scientific article published in March 2015

Pharmacogenetics of topical and systemic treatment of psoriasis.

scientific article published on October 2013

Pharmacokinetics and pharmacodynamics of a single bolus of propofol 2% in healthy volunteers

scientific article published in April 2003

Polymorphisms Associated with Age at Onset in Patients with Moderate-to-Severe Plaque Psoriasis.

scientific article

Polymorphisms in CYP1A2, CYP2C9 and ABCB1 affect agomelatine pharmacokinetics

scientific article published on 21 February 2019

Polymorphisms in CYP2D6 have a greater effect on variability of risperidone pharmacokinetics than gender

article published in 2015

Polymorphisms influencing olanzapine metabolism and adverse effects in healthy subjects

scientific article

Regulation of bronchial tone in chronic obstructive pulmonary disease (COPD): role of muscarinic receptors

scientific article published in April 2003

Retroperitoneal haematoma in a patient treated with acenocoumarol, phenytoin and paroxetine

scientific article published on 01 June 1995

Safety and cardiovascular effects of multiple-dose administration of aripiprazole and olanzapine in a randomised clinical trial

scientific article published on 29 September 2020

The comparative hemodynamic effects of intravenous IQB-9302 and bupivacaine in anesthetized rats

scientific article published in May 2004

The effect of CYP2D6 variation on antipsychotic-induced hyperprolactinaemia: a systematic review and meta-analysis

scientific article published on 04 February 2020

The polymorphism rs763780 in the IL-17F gene is associated with response to biological drugs in patients with psoriasis.

scientific article published on 29 September 2015

The relationship between tumour necrosis factor (TNF)-α promoter and IL12B/IL-23R genes polymorphisms and the efficacy of anti-TNF-α therapy in psoriasis: a case-control study

scientific article published in October 2013

Toward a clinical practice guide in pharmacogenomics testing for functional polymorphisms of drug-metabolizing enzymes. Gene/drug pairs and barriers perceived in Spain

scientific article published on 26 November 2012

Treatment of mild cognitive impairment: value of citicoline

scientific article published in October 2002

Ulnar nerve block induced by the new local anesthetic IQB-9302 in healthy volunteers: a comparison with bupivacaine

scientific article published in November 2001

Use of Exposure Data to Establish Causality in Drug–Adverse Event Relationships: An Example with Desvenlafaxine

scientific article published in 2024

Use of non-specific intravenous human immunoglobulins in Spanish hospitals; need for a hospital protocol

scientific article published on 05 March 2010

Use of pharmacogenetics in bioequivalence studies to reduce sample size: an example with mirtazapine and CYP2D6.

scientific article published on 26 June 2012

Utility of Pilot Studies for Predicting Ratios and Intrasubject Variability in High-Variability Drugs.

scientific article

Utility of assessing thiopurine S-methyltransferase polymorphisms before azathioprine therapy.

scientific article

Validation of a genotyping method for analysis of TPMT polymorphisms.

scientific article published on 14 March 2012

[Cost-effectiveness analysis of the eradication of Helicobacter pylori as treatment for duodenal ulcer]

scientific article published on 01 October 1998

[Electronic medical record in clinical trials of effectiveness of drugs integrated in clinical practice]

scientific article published on 23 April 2015

[New antiviral agents in chronic viral hepatitis]

scientific article published on 01 February 1998

[Regulation and evaluation of clinical trials of cell therapy]

scientific article published on 22 April 2010

[Study of genetic polymorphisms in the tumor necrosis factor α promoter region in Spanish patients with psoriasis]

scientific article published on 20 December 2011

[The current state of citicholine in cerebral ischemia]

scientific article published on 01 April 2000

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