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List of works by Christian Brander

A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell Immune Responses in HIV-1-Infected Subjects on HAART.

scientific article

A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques

scientific article

A minimal T-cell immunogen designed to cover HIV-1 specificities associated with control is immunogenic in mice and breaks CTL immunodominance

scientific article

A minor population of macrophage-tropic HIV-1 variants is identified in recrudescing viremia following analytic treatment interruption

scientific article published on 16 April 2020

A novel immunodominant CD8+ T cell response restricted by a common HLA-C allele targets a conserved region of Gag HIV-1 clade CRF01_AE infected Thais

scientific article

A quantitative analysis of the variables affecting the repertoire of T cell specificities recognized after vaccinia virus infection

scientific article

A statistical framework for modeling HLA-dependent T cell response data

scientific article

AAAS joins the Translational Medicine family

scientific article published on 7 May 2009

Absence of biologically important Kaposi sarcoma-associated herpesvirus gene products and virus-specific cellular immune responses in multiple myeloma

scientific article published on July 2002

Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine ⬇️

scientific article published on July 1, 1995

Adaptation of HIV-1 to human leukocyte antigen class I

scientific article published on 25 February 2009

Additive contribution of HLA class I alleles in the immune control of HIV-1 infection

scientific article published on 21 July 2010

Altered response hierarchy and increased T-cell breadth upon HIV-1 conserved element DNA vaccination in macaques

scientific article

Alternative effector-function profiling identifies broad HIV-specific T-cell responses in highly HIV-exposed individuals who remain uninfected

scientific article published on 23 September 2014

Amino-acid co-variation in HIV-1 Gag subtype C: HLA-mediated selection pressure and compensatory dynamics

scientific article

Anti-HBs re-seroconversion after liver transplantation in a patient with past HBV infection receiving a HBsAg positive graft

scientific article published on 25 December 2008

Availability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitope

scientific article published on June 2007

Balance between activation and regulation of HIV-specific CD8+ T-cell response after modified vaccinia Ankara B therapeutic vaccination

scientific article

Benzyl-2-Acetamido-2-Deoxy-α-d-Galactopyranoside Increases Human Immunodeficiency Virus Replication and Viral Outgrowth Efficacy In Vitro.

scientific article published in January 2017

Broad and Gag-biased HIV-1 epitope repertoires are associated with lower viral loads

scientific article

CD8+ T-cell responses to different HIV proteins have discordant associations with viral load

scientific article published on 17 December 2006

CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control

scientific article (publication date: 2012)

Capturing viral diversity for in-vitro test reagents and HIV vaccine immunogen design

scientific article published on May 2007

Carrier-mediated uptake and presentation of a major histocompatibility complex class I-restricted peptide.

scientific article published on December 1993

Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells

scientific article

Cellular immune responses and disease control in acute AIDS-associated Kaposi's sarcoma

scientific article published in September 2009

Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection.

scientific article

Central role of reverting mutations in HLA associations with human immunodeficiency virus set point

scientific article published on 2 July 2008

Characterization of full-length hepatitis C virus genotype 4 sequences.

scientific article published in May 2007

Characterization of lidocaine-specific T cells

scientific article published on February 1997

Clonotype tracking of TCR repertoires during chronic virus infections.

scientific article published on December 2002

Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses.

scientific article

Comparison of Safety and Vector-Specific Immune Responses in Healthy and HIV-Infected Populations Vaccinated with MVA-B

scientific article published on 07 November 2019

Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses

scientific article published in April 2003

Compensatory Mutation Partially Restores Fitness and Delays Reversion of Escape Mutation within the Immunodominant HLA-B*5703-Restricted Gag Epitope in Chronic Human Immunodeficiency Virus Type 1 Infection

Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection

scientific article

Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides

scientific article published on May 2004

Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.

scientific article

Consequences of HLA-B*13-Associated Escape Mutations on HIV-1 Replication and Nef Function

scientific article

Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities

scientific article published on March 2004

Contribution of immunological and virological factors to extremely severe primary HIV type 1 infection

scientific article

Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes

scientific article published on 20 December 2005

Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes

scientific article published on 24 January 2007

Correction to: Novel Approaches Towards a Functional Cure of HIV/AIDS

scientific article published on 03 June 2020

Correction to: iHIVARNA phase IIa, a randomized, placebo-controlled, double-blinded trial to evaluate the safety and immunogenicity of iHIVARNA-01 in chronically HIV-infected patients under stable combined antiretroviral therapy

scientific article published on 13 December 2019

Correction: Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1

article

Correction: Identification of Immunogenic Cytotoxic T Lymphocyte Epitopes Containing Drug Resistance Mutations in Antiretroviral Treatment-Naïve HIV-Infected Individuals

scientific article

Corrigendum to 'Therapeutic vaccination refocuses T-cell responses towards conserved regions of HIV-1 in early treated individuals (BCN 01 study)' EClinicalMedicine 11 (2019) 65-80

scientific article published on 10 January 2020

Cross-reactivity of T cell lines and clones to beta-lactam antibiotics

scientific article published on August 1996

Cytotoxic HIV-1 p55ᵍᵃᵍ-Specific CD4+ T Cells Produce HIV-Inhibitory Cytokines and Chemokines

scholarly article

DNA vaccines expressing conserved elements provide potent and broad immune responses

scientific article published on 13 September 2012

De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection

scientific article

Decreased CXCR3+ CD8 T cells in advanced human immunodeficiency virus infection suggest that a homing defect contributes to cytotoxic T-lymphocyte dysfunction

scientific article

Defective immune function of primary effusion lymphoma cells is associated with distinct KSHV gene expression profiles.

scientific article published in June 2004

Defining the HLA class I-associated viral antigen repertoire from HIV-1-infected human cells

scientific article published on 15 October 2015

Definition of an optimal cytotoxic T lymphocyte epitope in the latently expressed Kaposi's sarcoma-associated herpesvirus kaposin protein

scientific article

Definition of the viral targets of protective HIV-1-specific T cell responses

scientific article published on 7 December 2011

Design, expression, and processing of epitomized hepatitis C virus-encoded CTL epitopes

scientific article published on November 2008

Detection of HIV-1-specific T-cell immune responses in highly HIV-exposed uninfected individuals by in-vitro dendritic cell co-culture

scientific article published on July 2015

Determinant of HIV-1 mutational escape from cytotoxic T lymphocytes

scientific article

Development and Preclinical Evaluation of an Integrase Defective Lentiviral Vector Vaccine Expressing the HIVACAT T Cell Immunogen in Mice

scientific article published on 04 February 2020

Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians

scientific article published in May 2004

Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection

scientific article published on 22 November 2017

Differential Immunogenicity of HIV‐1 Clade C Proteins in Eliciting CD8+and CD4+Cell Responses

article

Differential boosting of innate and adaptive antiviral responses during pegylated-interferon-alpha therapy of chronic hepatitis B.

scientific article published on 6 October 2012

Differential clade-specific HLA-B*3501 association with HIV-1 disease outcome is linked to immunogenicity of a single Gag epitope

scientific article published on 12 September 2012

Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints

scientific article published on 05 February 2014

Differential narrow focusing of immunodominant human immunodeficiency virus gag-specific cytotoxic T-lymphocyte responses in infected African and caucasoid adults and children.

scientific article

Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes

scientific article

Differential prevalence of the HLA-C −35 CC genotype among viremic long term non-progressor and elite controller HIV+ individuals

article

Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype.

scientific article published in October 2006

Differential targeting and shifts in the immunodominance of Epstein-Barr virus--specific CD8 and CD4 T cell responses during acute and persistent infection

scientific article

Direct interrogation of viral peptides presented by the class I HLA of HIV-infected T cells

scientific article

Discovery and characterization of highly immunogenic and broadly recognized mimics of the HIV-1 CTL epitope Gag77-85.

scientific article

Discrimination of human CD4 T cell clones based on their reactivity with antigen-presenting T cells

scientific article

Dominant Epstein-Barr virus-specific T-cell responses are maintained during moderate and intense immunosuppressive treatment

scientific article published on 19 July 2010

Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

scientific article published in December 2004

E 7 (CD103) Expression Identifies a Highly Active, Tonsil-Resident Effector-Memory CTL Population

scientific article published on 01 October 2005

Early Detection Of Hiv Infection And Of Asymptomatic Sexually Transmitted Infections Among Men Who Have Sex With Men.

scientific article published on 23 August 2017

Early and late cytotoxic T lymphocyte responses in HIV infection ⬇️

scientific article published on January 1, 2002

Effect of maraviroc intensification on HIV-1-specific T cell immunity in recently HIV-1-infected individuals

scientific article published on 27 January 2014

Effective T-cell responses select human immunodeficiency virus mutants and slow disease progression

scientific article published on 4 April 2007

Efficient generation of human T cells from a tissue-engineered thymic organoid

scientific article published on 01 July 2000

Efficient processing of the immunodominant, HLA-A*0201-restricted human immunodeficiency virus type 1 cytotoxic T-lymphocyte epitope despite multiple variations in the epitope flanking sequences

scientific article

Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences

scientific article

Erratum: addendum: HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus

scientific article published in Nature

Escape from highly effective public CD8+ T-cell clonotypes by HIV

scientific article published on 6 July 2011

Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication

scientific article

Ets-1 maintains IL-7 receptor expression in peripheral T cells

scientific article

Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1

scientific article

Evolution and transmission of stable CTL escape mutations in HIV infection

scientific article published in Nature

Ex vivo production of autologous whole inactivated HIV-1 for clinical use in therapeutic vaccines

article

Expanded Epitope Recognition by Vaccination with DNA Encoding Novel Immunogens Comprising HIV Conserved Elements

article

Expansion of HIV-specific CD4+ and CD8+ T cells by dendritic cells transfected with mRNA encoding cytoplasm- or lysosome-targeted Nef

scientific article published on 25 October 2005

Expansion of antibody secreting cells and modulation of neutralizing antibody activity in HIV infected individuals undergoing structured treatment interruptions

scientific article published on 22 February 2013

Expansion of interferon-γ-secreting HIV-specific T cells during successful antiretroviral therapy

scientific article

Extensive HLA class I allele promiscuity among viral CTL epitopes

scientific article published on September 2007

Extensive intrasubtype recombination in South African human immunodeficiency virus type 1 subtype C infections

scientific article published on 21 February 2007

FARMS: A New Algorithm for Variable Selection

scientific article

Fine specificity and cross-clade reactivity of HIV type 1 Gag-specific CD4+ T cells

scientific article published on March 2004

Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1

scientific article

Founder Effects in the Assessment of HIV Polymorphisms and HLA Allele Associations

scientific article published in Science

Functional classification of class II human leukocyte antigen (HLA) molecules reveals seven different supertypes and a surprising degree of repertoire sharing across supertypes

scientific article published on 9 February 2011

Functionally inert HIV-specific cytotoxic T lymphocytes do not play a major role in chronically infected adults and children

scientific article

Gradual adaptation of HIV to human host populations: good or bad news?

article

Guiding the humoral response against HIV-1 toward a MPER adjacent region by immunization with a VLP-formulated antibody-selected envelope variant

scientific article published in PLoS ONE

Gut Microbiota Linked to Sexual Preference and HIV Infection.

scientific article

HCV-induced immune responses influence the development of operational tolerance after liver transplantation in humans

scientific article published on June 2014

HIV LTR-Driven Antisense RNA by Itself Has Regulatory Function and May Curtail Virus Reactivation From Latency.

scientific article

HIV T-Cell Vaccines

scientific article published on 01 January 2018

HIV evolution: CTL escape mutation and reversion after transmission

scientific article published on 8 February 2004

HIV patients developing primary CNS lymphoma lack EBV-specific CD4+ T cell function irrespective of absolute CD4+ T cell counts

scientific article

HIV subtype influences HLA-B*07:02-associated HIV disease outcome

scientific article

HIV viral diversity and escape from cellular immunity

article

HIV-1 DNA decay dynamics in early treated individuals: practical considerations for clinical trial design

scientific article published on 17 April 2020

HIV-1 over time: fitness loss or robustness gain?

article

HIV-1 p24 derived epitopes modulate KIR2DL2-binding to HLA-Cw03.

scientific article published on 13 September 2012

HIV-1 p24(gag) derived conserved element DNA vaccine increases the breadth of immune response in mice

scientific article

HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus

scientific article published in November 2002

HIV-1 vaccination--is there hope?

scientific article

HIV-specific CD8 T cells express low levels of IL-7Ralpha: implications for HIV-specific T cell memory

scientific article published on 24 July 2006

HIVconsv Vaccines and Romidepsin in Early-Treated HIV-1-Infected Individuals: Safety, Immunogenicity and Effect on the Viral Reservoir (Study BCN02)

scientific article published on 06 May 2020

HLA class I protective alleles in an HIV-1-infected subject homozygous for CCR5-Δ32/Δ32.

scientific article published on 28 June 2012

HLA class I supertypes: a revised and updated classification

scientific article

HLA class I-driven evolution of human immunodeficiency virus type 1 subtype c proteome: immune escape and viral load

scientific article published on 23 April 2008

HLA-B*35-PX and HLA-B*35-PY subtype differentiation does not predict observed differences in level of HIV control in a Peruvian MSM cohort

article

HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphocyte Recognition.

scientific article published in June 2009

HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition

scientific article published on 30 December 2008

HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load

scientific article

HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins

scientific article

Heat shock protein-mediated cross-presentation of exogenous HIV antigen on HLA class I and class II.

scientific article published on August 2004

Heterogeneous T cell responses to beta-lactam-modified self-structures are observed in penicillin-allergic individuals.

scientific article published on September 1995

High degree of inter-clade cross-reactivity of HIV-1-specific T cell responses at the single peptide level.

scientific article published in September 2005

High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control

scientific article published on 13 July 2011

Highly pathogenic adapted HIV-1 strains limit host immunity and dictate rapid disease progression

scientific article published on June 2014

Host ethnicity and virus genotype shape the hepatitis B virus-specific T-cell repertoire.

scientific article published on 17 September 2008

Human leukocyte antigen-associated sequence polymorphisms in hepatitis C virus reveal reproducible immune responses and constraints on viral evolution

scientific article published in August 2007

Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection

article

IL-8 responsiveness defines a subset of CD8 T cells poised to kill

scientific article published on 3 August 2004

Identification of Immunogenic Cytotoxic T Lymphocyte Epitopes Containing Drug Resistance Mutations in Antiretroviral Treatment-Naïve HIV-Infected Individuals

scientific article

Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses

scientific article

Identification of novel HLA-A2-restricted human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte epitopes predicted by the HLA-A2 supertype peptide-binding motif

scientific article

Immune Profiles Identification by Vaccinomics After MVA Immunization in Randomized Clinical Study

scientific article published on 10 November 2020

Immune correlates of HIV control.

scientific article published on January 2011

Immune screening identifies novel T cell targets encoded by antisense reading frames of HIV-1.

scientific article

Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection

scientific article

Immune-driven recombination and loss of control after HIV superinfection.

scientific article published on 14 July 2008

Immunosuppressive drugs asymmetrically impact circulating T cell counts and function.

scientific article

Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses

scientific article published in April 2006

Impact of Kaposi Sarcoma–Associated Herpesvirus (KSHV) Burden and HIV Coinfection on the Detection of T Cell Responses to KSHV ORF73 and ORF65 Proteins

article

Impact of intrapeptide epitope location on CD8 T cell recognition

Impact of select immunologic and virologic biomarkers on CD4 cell count decrease in patients with chronic HIV-1 subtype C infection: results from Sinikithemba Cohort, Durban, South Africa

scientific article published on September 2009

Important contribution of p15 Gag-specific responses to the total Gag-specific CTL responses

scientific article published on February 2002

In silico veritas? Potential limitations for SARS-CoV-2 vaccine development based on T-cell epitope prediction

scientific article published on 04 June 2020

In vivo Effects of Romidepsin on T-Cell Activation, Apoptosis and Function in the BCN02 HIV-1 Kick&Kill Clinical Trial

scientific article published on 20 March 2020

Increased Cytotoxic T-Lymphocyte Epitope Variant Cross-Recognition and Functional Avidity Are Associated with Hepatitis C Virus Clearance

scientific article

Increased breadth and depth of cytotoxic T lymphocytes responses against HIV-1-B Nef by inclusion of epitope variant sequences

scientific article (publication date: 28 March 2011)

Increased detection of HIV-specific T cell responses by combination of central sequences with comparable immunogenicity

article

Increased expression of SAMHD1 in a subset of HIV-1 elite controllers

scientific article published on 25 July 2014

Increased sequence diversity coverage improves detection of HIV-specific T cell responses

scientific article published in November 2007

Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice

scientific article published on 06 May 2009

Influenza, but not HIV-specific CTL epitopes, elicits delayed-type hypersensitivity (DTH) reactions in HIV-infected patients

article

Inhibition of human NK cell-mediated cytotoxicity by exposure to ammonium chloride.

scientific article published on June 2001

Kaposi sarcoma-associated herpesvirus (KSHV) seroprevalence in population-based samples of African children: evidence for at least 2 patterns of KSHV transmission

scientific article published on August 2009

Kaposi's sarcoma-associated herpesvirus-specific immune reconstitution and antiviral effect of combined HAART/chemotherapy in HIV clade C-infected individuals with Kaposi's sarcoma

scientific article

Lack of strong immune selection pressure by the immunodominant, HLA-A*0201-restricted cytotoxic T lymphocyte response in chronic human immunodeficiency virus-1 infection

scientific article published on June 1998

Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes

scientific article published on 15 May 2006

Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory act

scientific article

Liver transplantation from hepatitis B surface antigen positive donors: a safe way to expand the donor pool

article by Elisabetta Loggi et al published March 2012 in Journal of Hepatology

Lost in Translation: Obstacles to Translational Medicine

scientific article

Low nadir CD4+ T-cell counts predict gut dysbiosis in HIV-1 infection

article

Low-replicating viruses and strong anti-viral immune response associated with prolonged disease control in a superinfected HIV-1 LTNP elite controller

scientific article

Lymphocyte Activation Dynamics Is Shaped by Hereditary Components at Chromosome Region 17q12-q21

scientific article

Lytic and latent antigens of the human gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus induce T-cell responses with similar functional properties and memory phenotypes

scientific article published on 28 February 2007

Mechanisms involved in the Abacavir-mediated hypersensitivity syndrome

scientific article published on 10 July 2012

Mechanisms of abrupt loss of virus control in a cohort of previous HIV controllers

article

Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

scientific article published on 06 August 2020

Modulation of antibody secreting cells and neutralizing Ab activity in HIV infected individuals undergoing structured treatment interruptions

article

Mother-to-child transmission of HIV infection and CTL escape through HLA-A2-SLYNTVATL epitope sequence variation

article

Motif inference reveals optimal CTL epitopes presented by HLA class I alleles highly prevalent in southern Africa

scientific article

Multiple effector functions mediated by human immunodeficiency virus-specific CD4(+) T-cell clones

scientific article published on October 2001

Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes

scientific article published on 22 November 2006

Nef interference with HIV-1-specific CTL antiviral activity is epitope specific

scientific article published on August 2006

Novel Approaches Towards a Functional Cure of HIV/AIDS

scientific article published on 20 May 2020

Novel Nested Peptide Epitopes Recognized by CD4+ T Cells Induced by HIV-1 Conserved-Region Vaccines

scientific article published on 16 January 2020

Novel, in-natural-infection subdominant HIV-1 CD8+ T-cell epitopes revealed in human recipients of conserved-region T-cell vaccines

scientific article

P12-09. Immune responses in controlled and uncontrolled HIV infection to a designed HIV immunogen sequence focused on conserved regions of the viral genome

article

P16-24. Crucial contribution of sub-dominant HLA-C allele restricted CTL responses to the control of HIV

article

P16-41. Evidence for in vivo immune selection pressure exerted by HLA class I restricted CTL responses to anti-sense encoded HIV sequences.

scientific article published on 22 October 2009

Pathogenesis and treatment of HIV infection: the cellular, the immune system and the neuroendocrine systems perspective

scientific article

Pharmacokinetic/pharmacodynamic analysis of romidepsin used as an HIV latency reversing agent

scientific article published on 22 December 2020

Phase I clinical trial of an intranodally administered mRNA based therapeutic vaccine against HIV-1 infection

article

Preclinical evaluation of an mRNA HIV vaccine combining rationally selected antigenic sequences and adjuvant signals (HTI-TriMix).

scientific article published on 24 September 2016

Priming with Recombinant BCG Expressing HTI Enhances the Magnitude and Breadth of the T-Cell Immune Responses Elicited by MVA.HTI in BALB/c Mice

scientific article published on 13 November 2020

Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1.

scientific article

Provir/Latitude 45 study: A step towards a multi-epitopic CTL vaccine designed on archived HIV-1 DNA and according to dominant HLA I alleles

article

Psychological stress is associated with high levels of IL-6 in HIV-1 infected individuals on effective combined antiretroviral treatment

scientific article published on 25 January 2012

Rare HLA drive additional HIV evolution compared to more frequent alleles

scientific article published on March 2009

Receptor-ligand requirements for increased NK cell polyfunctional potential in slow progressors infected with HIV-1 coexpressing KIR3DL1*h/*y and HLA-B*57

scientific article

Recognition of HIV-1 peptides by host CTL is related to HIV-1 similarity to human proteins

scientific article

Recombinant BCG Expressing HTI Prime and Recombinant ChAdOx1 Boost Is Safe and Elicits HIV-1-Specific T-Cell Responses in BALB/c Mice

scientific article published on 02 August 2019

Relative dominance of Gag p24-specific cytotoxic T lymphocytes is associated with human immunodeficiency virus control

scientific article

Rewarding patient-directed research: Excellence in Translational Medicine Award

scientific article published on 3 May 2006

S011-06 OA. HIV specific T cell responses and response patterns associated with viral control independent of classical non-progessor HLA class I alleles.

scientific article published on 22 October 2009

SARS-CoV-2 Consensus-Sequence and Matching Overlapping Peptides Design for COVID19 Immune Studies and Vaccine Development

scientific article published on 06 August 2020

Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1.

scientific article published on 26 February 2015

Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection

scientific article

Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution

scientific article

Sequence variations in HIV-1 p24 Gag-derived epitopes can alter binding of KIR2DL2 to HLA-C*03:04 and modulate primary natural killer cell function

scientific article published on June 2014

Simultaneous assessment of cytotoxic T lymphocyte responses against multiple viral infections by combined usage of optimal epitope matrices, anti- CD3 mAb T-cell expansion and "RecycleSpot"

scientific article

Single-stranded RNA derived from HIV-1 serves as a potent activator of NK cells

scientific article published in June 2007

Small steps forward for HIV vaccine development

scientific article published on 02 April 2020

Specificity of CD8+ T-Cell Responses Following Vaccination with Conserved Regions of HIV-1 in Nairobi, Kenya

scientific article published on 29 May 2020

Stimulation of human cytotoxic T cells with HIV-1-derived peptides presented by recombinant HLA-A2 peptide complexes

article

Strong sex bias in elite control of paediatric HIV infection

article

Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid

scientific article published on 2 April 2008

Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection

scientific article

Substantial regional differences in human herpesvirus 8 seroprevalence in sub-Saharan Africa: insights on the origin of the "Kaposi's sarcoma belt"

scientific article

Sustained and focused hepatitis B virus nucleocapsid-specific T-cell immunity in liver transplant recipients compared to individuals with chronic and self-limited hepatitis B virus infection

scientific article published in April 2008

T cell receptor cross-recognition of an HIV-1 CD8+ T cell epitope presented by closely related alleles from the HLA-A3 superfamily

article

T-cell immunity to Kaposi sarcoma-associated herpesvirus: recognition of primary effusion lymphoma by LANA-specific CD4+ T cells

scientific article published on 10 January 2012

TL1A-DR3 Plasma Levels Are Predictive of HIV-1 Disease Control, and DR3 Costimulation Boosts HIV-1-Specific T Cell Responses

scientific article published on 11 November 2020

TOX is expressed by exhausted and polyfunctional human effector memory CD8+ T cells

scientific article published on 01 July 2020

The HIV-1 regulatory proteins Tat and Rev are frequently targeted by cytotoxic T lymphocytes derived from HIV-1-infected individuals

scientific article

The HLA-C*04: 01/KIR2DS4 gene combination and human leukocyte antigen alleles with high population frequency drive rate of HIV disease progression

scientific article published on March 2015

The challenges of host and viral diversity in HIV vaccine design

scientific article published on 13 June 2006

The genome-wide methylation profile of CD4+ T cells from HIV-infected individuals identifies distinct patterns associated with disease progression

scientific article published on 26 July 2020

The leukotriene B4 lipid chemoattractant receptor BLT1 defines antigen-primed T cells in humans

scientific article published on 22 September 2005

The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design

scientific article

The potential of heat shock protein-peptide complexes as a therapeutic HIV vaccine.

scientific article published on September 2005

Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study)

scientific article published on 01 May 2019

Therapeutic Vaccine in Chronically HIV-1-Infected Patients: A Randomized, Double-Blind, Placebo-Controlled Phase IIa Trial with HTI-TriMix

scientific article published on 06 December 2019

Transfusion-transmitted infections

scientific article (publication date: 6 June 2007)

Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA.

scientific article

Treatment-dependent loss of polyfunctional CD8+ T-cell responses in HIV-infected kidney transplant recipients is associated with herpesvirus reactivation

scientific article published on April 2009

Uncommon pathways of immune escape attenuate HIV-1 integrase replication capacity

scientific article

Use of Antibodies as Carriers for T-Cell Epitopes ⬇️

scientific article published on January 1, 1991

Use of antibody/peptide constructs to direct antigenic peptides to T cells: Evidence for T cell processing and presentation ⬇️

scientific article published on January 1, 1992

Viral adaptation to immune selection pressure by HLA class I-restricted CTL responses targeting epitopes in HIV frameshift sequences

scientific article

Viral immunology. Comprehensive serological profiling of human populations using a synthetic human virome

scientific article

Virological and immunological outcome of treatment interruption in HIV-1-infected subjects vaccinated with MVA-B.

scientific article published on 27 September 2017

Virological, immune and host genetics markers in the control of HIV infection

scientific article published on January 2009

Virus-specific immune response in HBeAg-negative chronic hepatitis B: relationship with clinical profile and HBsAg serum levels

scientific article

Vpr Is Preferentially Targeted by CTL During HIV-1 Infection

article

Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection

scientific article published on 8 March 2012

Zip6 Transporter Is an Essential Component of the Lymphocyte Activation Machinery

scientific article published on 14 December 2018

iHIVARNA phase IIa, a randomized, placebo-controlled, double-blinded trial to evaluate the safety and immunogenicity of iHIVARNA-01 in chronically HIV-infected patients under stable combined antiretroviral therapy

scientific article published on 17 June 2019

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