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List of works by David W. Borhani

2,4-Diaminopyrimidine MK2 inhibitors. Part I: Observation of an unexpected inhibitor binding mode

scientific article

2,4-Diaminopyrimidine MK2 inhibitors. Part II: Structure-based inhibitor optimization

scientific article published on 29 October 2009

A-420983: a potent, orally active inhibitor of lck with efficacy in a model of transplant rejection

scientific article published in May 2004

Atomic structures of human dihydrofolate reductase complexed with NADPH and two lipophilic antifolates at 1.09 a and 1.05 a resolution

scientific article

Comment on "A Bacterium That Can Grow by Using Arsenic Instead of Phosphorus"

scientific article

Covalent JNK inhibitors?

scholarly article

Crystal structure of Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase with XMP, pyrophosphate, and two Mg(2+) ions bound: insights into the catalytic mechanism

scientific article

Crystal structure of the ectodomain of human transferrin receptor

scientific article

Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation

scientific article

Crystallization and X-ray diffraction studies of a soluble form of the human transferrin receptor

scientific article published in April 1991

Crystallization of the Mycobacterium tuberculosis cell-division protein FtsZ

scientific article published on 01 December 2000

Crystallization of truncated human apolipoprotein A-I in a novel conformation

scientific article published on 01 September 1999

Discovery and Characterization of Non-ATP Site Inhibitors of the Mitogen Activated Protein (MAP) Kinases ⬇️

scientific article published on January 20, 2011

Discovery of A-770041, a src-family selective orally active lck inhibitor that prevents organ allograft rejection

scientific article

Dynamic control of slow water transport by aquaporin 0: implications for hydration and junction stability in the eye lens

scientific article

Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor

scientific article

Exploring atomic resolution physiology on a femtosecond to millisecond timescale using molecular dynamics simulations

scientific article

Human apolipoprotein A-I: structure determination and analysis of unusual diffraction characteristics

scientific article published on 01 December 1999

Include Israel when comparing metrics ⬇️

scientific article published on March 3, 2011

Mechanism of voltage gating in potassium channels

scientific article published on April 2012

Michellamine alkaloids inhibit protein kinase C.

scientific article

Pathway and mechanism of drug binding to G-protein-coupled receptors.

scientific article

Polymerization of C-terminally truncated Mycobacterium tuberculosis FtsZ is unlikely to be physiologically relevant

scientific article published on 01 December 2004

Principles of conduction and hydrophobic gating in K+ channels

scientific article

Rational mutagenesis to support structure-based drug design: MAPKAP kinase 2 as a case study

scientific article

Rethinking clinical trials: biology's mysteries

scientific article published on 01 December 2011

SIGNAL TRANSDUCTION. Structural basis for nucleotide exchange in heterotrimeric G proteins

scientific article

Slow polymerization of Mycobacterium tuberculosis FtsZ

scientific article

Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs.

scientific article published on 13 October 2013

Structural models of human apolipoprotein A-I: a critical analysis and review

scientific article

Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches

scientific article published in September 2004

The future of molecular dynamics simulations in drug discovery ⬇️

scientific article published on December 20, 2011

Unusual Water-mediated Antigenic Recognition of the Proinflammatory Cytokine Interleukin-18

scientific article

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