List of works - Gillian A Gray

11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI. ⬇️

scientific article published on June 2017

A Nonradioactive Method for Localization of Endothelin Receptor mRNA In Situ

scientific article published on 01 January 1998

A Protocol for Improved Measurement of Arterial Flow Rate in Preclinical Ultrasound

scientific article

A tail of translational regulation

scientific article published on 27 June 2017

Activation of endothelin ETA receptors masks the constrictor role of endothelin ETB receptors in rat isolated small mesenteric arteries

scientific article published in April 1997

Advancing our understanding of the pathophysiology of cardiac disease using in vivo assessment of heart structure and function in rodent models ⬇️

scientific article published on November 9, 2012

An L-arginine-derived factor mediates endotoxin-induced vascular hyposensitivity to calcium

scientific article published in November 1990

Application of kt-BLAST acceleration to reduce cardiac MR imaging time in healthy and infarcted mice

scientific article

Are there different ETB receptors mediating constriction and relaxation?

scientific article published on 01 January 1995

Assessment of spectral Doppler in preclinical ultrasound using a small-size rotating phantom

scientific article

Biological sex themed section: incorporating the female dimension into cardiovascular pharmacology

scientific article published on February 2014

Bone marrow transplantation modulates tissue macrophage phenotype and enhances cardiac recovery after subsequent acute myocardial infarction

scientific article published on 11 December 2015

Bradykinin B1 receptor-mediated vasodilation is impaired in myometrial arteries from women with pre-eclampsia

scientific article

Cardiac GR and MR: From Development to Pathology

scientific article

Cardiomyocyte and Vascular Smooth Muscle-Independent 11β-Hydroxysteroid Dehydrogenase 1 Amplifies Infarct Expansion, Hypertrophy, and the Development of Heart Failure After Myocardial Infarction in Male Mice

scientific article

Cardiovascular risk in women: the impact of hormone replacement therapy and prospects for new therapeutic approaches

scientific article published on February 2007

Characterization of endothelin receptors mediating contraction of rabbit saphenous vein

scientific article published on 01 March 1994

Constriction to ETB receptor agonists, BQ-3020 and sarafotoxin s6c, in human resistance and capacitance vessels in vivo.

scientific article published on July 2000

Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

scientific article

Deletion of Endothelial Cell Endothelin B Receptors Does Not Affect Blood Pressure or Sensitivity to Salt

Dependence of endotoxin-induced vascular hyporeactivity on extracellular L-arginine.

scientific article published on January 1993

Development and characterization of rodent cardiac phantoms: comparison with in vivo cardiac imaging

scientific article

Diesel exhaust particulate induces pulmonary and systemic inflammation in rats without impairing endothelial function ex vivo or in vivo

scientific article

Differential Effects of Angiotensin II on Cardiac Cell Proliferation and Intramyocardial Perivascular Fibrosis In Vivo

scientific article published on 01 December 1998

Effect of dexamethasone on the onset and persistence of vascular hyporeactivity induced by E. coli lipopolysaccharide in rats

scientific article

Effect of endotoxin on circulating cyclic GMP in the rat.

scientific article published in February 1992

Effects of calcium channel blockade on the aortic intima in spontaneously hypertensive rats

scientific article published on 01 October 1993

Effects of methylene blue on blood pressure and reactivity to norepinephrine in endotoxemic rats

scientific article published in June 1993

Endothelial cell-specific ETB receptor knockout: autoradiographic and histological characterisation and crucial role in the clearance of endothelin-1.

scientific article

Endothelin receptors that modulate contraction of the rat fundus

scientific article published on 01 January 1995

Endothelin-1[1-31] is Not Elevated in Men with Chronic Heart Failure

scientific article published on 01 November 2004

Endothelins are potent vasoconstrictors, and much more besides

scientific article published on 01 February 2000

Endothelium-derived hyperpolarizing factor and potassium use different mechanisms to induce relaxation of human subcutaneous resistance arteries

scientific article

Endotoxin-induced impairment of vascular reactivity in the pithed rat: role of arachidonic acid metabolites.

scientific article published in August 1990

Endotoxin-induced impairment of vasodepressor responses in the pithed rat

article

Enhanced angiogenic capacity of human umbilical vein endothelial cells from women with preeclampsia.

scientific article

Enhanced monocyte recruitment and delayed alternative macrophage polarization accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice

scientific article published on 17 June 2019

Enhancement of the hypothermic response of mice to delta-9-tetrahydrocannabinol by subhypothermic doses of chlorpromazine and phentolamine

scientific article published on 01 February 1987

Evidence that an l-arginine/nitric oxide dependent elevation of tissue cyclic GMP content is involved in depression of vascular reactivity by endotoxin ⬇️

scientific article published on May 1, 1991

Forearm vasoconstriction to endothelin-1 is mediated by ETA and ETB receptors in vivo in humans

scientific article published on 01 January 1995

Functional heterogeneity of large and small resistance arteries isolated from biopsies of subcutaneous fat: implications for investigation of vascular pathophysiology.

scientific article

Getting to the heart of intracellular glucocorticoid regeneration: 11β-HSD1 in the myocardium

scientific article

Glucocorticoid receptor alters isovolumetric contraction and restrains cardiac fibrosis

scientific article published on 05 January 2017

High-resolution echocardiography in the assessment of cardiac physiology and disease in preclinical models

scientific article

Human myocardial pericytes: multipotent mesodermal precursors exhibiting cardiac specificity.

scientific article

Human urotensin II increases coronary perfusion pressure in the isolated rat heart

scientific article published on 01 June 2001

Imaging the healing murine myocardial infarct in vivo: ultrasound, magnetic resonance imaging and fluorescence molecular tomography

scientific article published on 12 October 2012

Immunolocalisation and activity of DDAH I and II in the heart and modification post-myocardial infarction.

scientific article published on 29 May 2009

Improved heart function follows enhanced inflammatory cell recruitment and angiogenesis in 11betaHSD1-deficient mice post-MI.

scientific article published on 21 May 2010

In vivo pharmacology of Ro 46-2005, the first synthetic nonpeptide endothelin receptor antagonist: implications for endothelin physiology.

scientific article published in January 1993

Increased vascular responsiveness to norepinephrine in rats with heart failure is endothelium dependent. Dissociation of basal and stimulated nitric oxide release

scientific article published on 01 January 1994

Incubation with endotoxin activates the L-arginine pathway in vascular tissue

scientific article published in September 1990

Inducible but not constitutive production of nitric oxide by vascular smooth muscle cells

scientific article published on 01 August 1991

Influence of endothelium on induction of the L-arginine-nitric oxide pathway in rat aortas

scientific article published in April 1993

Influence of scanning frequency and ultrasonic contrast agent on reproducibility of left ventricular measurements in the mouse

scientific article published in February 2005

Investigation of the endothelin system in experimental heart failure

scientific article published on 01 January 2002

Investigation of the selectivity of alpha, beta-methylene ATP in inhibiting vascular responses of the rat in vivo and in vitro

scientific article published on April 1990

Localization and function of ET-1 and ET receptors in small arteries post-myocardial infarction: upregulation of smooth muscle ET(B) receptors that modulate contraction

scientific article published on August 2000

Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway

scientific article published in October 1990

Manganese-Enhanced T Mapping in the Myocardium of Normal and Infarcted Hearts

scientific article published on 25 October 2018

Medroxyprogesterone acetate inhibits the cardioprotective effect of estrogen in experimental ischemia-reperfusion injury

scientific article published in January 2006

MicroRNA-148b Targets the TGF-β Pathway to Regulate Angiogenesis and Endothelial-to-Mesenchymal Transition during Skin Wound Healing

scientific article published on 08 May 2018

Nitric oxide and gall-bladder motor function

scientific article published on 01 May 1998

Oestrogen and the cardiovascular system: the good, the bad and the puzzling.

scientific article

Oestrogen-mediated cardioprotection following ischaemia and reperfusion is mimicked by an oestrogen receptor (ER)alpha agonist and unaffected by an ER beta antagonist

scientific article

Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist

scientific article published in Nature

Preventing local regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1 enhances angiogenesis

scientific article

Prolonged effect of a novel S-nitrosated glyco-amino acid in endothelium-denuded rat femoral arteries: potential as a slow release nitric oxide donor drug

scientific article published in December 1997

Pulmonary diesel particulate increases susceptibility to myocardial ischemia/reperfusion injury via activation of sensory TRPV1 and β1 adrenoreceptors

scientific article

Regulation of the Myocardial Endothelin System by Angiotensin-II and Losartan

scientific article published on 01 November 2000

Resident cells of the myocardium: more than spectators in cardiac injury, repair and regeneration

scientific article published on 01 February 2018

Run for your life: exercise, oxidative stress and the ageing endothelium

scientific article published in September 2009

Sarafotoxin 6c (S6c) reduces infarct size and preserves mRNA for the ETB receptor in the ischemic/reperfused myocardium of anesthetized rats

scientific article published in August 2004

Statistical considerations in reporting cardiovascular research

Structural changes and cyclic GMP content of the aorta after calcium antagonism or angiotensin converting enzyme inhibition in renovascular hypertensive rats

scientific article published on 01 July 1995

Systemic Blockade of the Endothelin-B Receptor Increases Peripheral Vascular Resistance in Healthy Men

scientific article published on 01 January 1999

Targeting C-reactive protein for the treatment of cardiovascular disease.

scientific article

The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an 'M2' phenotype in response to Th2 immunologic challenge.

scientific article published on 7 February 2015

The effect of inhibitors of the L-arginine/nitric oxide pathway on endotoxin-induced loss of vascular responsiveness in anaesthetized rats.

scientific article published on May 1991

The endothelin ETB receptor mediates both vasodilation and vasoconstriction in vivo

scientific article published on 01 July 1992

The endothelin system and its potential as a therapeutic target in cardiovascular disease.

scientific article

The role of endothelin in experimental cerebral vasospasm

scientific article published on July 1995

Therapeutic Potential of S-Nitrosothiols as Nitric Oxide Donor Drugs

scientific article published on 01 June 1997

Vasodilator Effects of Endothelin-Converting Enzyme Inhibition and Endothelin ET A Receptor Blockade in Chronic Heart Failure Patients Treated With ACE Inhibitors

scientific article published on 01 November 1996

acoustic assessment of a konjac–carrageenan tissue-mimicking material aT 5–60 MHZ

scientific article

αv integrins on mesenchymal cells regulate skeletal and cardiac muscle fibrosis.

scientific article

List of works by Gillian A Gray

11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI. ⬇️

A Nonradioactive Method for Localization of Endothelin Receptor mRNA In Situ

A Protocol for Improved Measurement of Arterial Flow Rate in Preclinical Ultrasound

A tail of translational regulation

Activation of endothelin ETA receptors masks the constrictor role of endothelin ETB receptors in rat isolated small mesenteric arteries

Advancing our understanding of the pathophysiology of cardiac disease using in vivo assessment of heart structure and function in rodent models ⬇️

An L-arginine-derived factor mediates endotoxin-induced vascular hyposensitivity to calcium

Application of kt-BLAST acceleration to reduce cardiac MR imaging time in healthy and infarcted mice

Are there different ETB receptors mediating constriction and relaxation?

Assessment of spectral Doppler in preclinical ultrasound using a small-size rotating phantom

Biological sex themed section: incorporating the female dimension into cardiovascular pharmacology

Bone marrow transplantation modulates tissue macrophage phenotype and enhances cardiac recovery after subsequent acute myocardial infarction

Bradykinin B1 receptor-mediated vasodilation is impaired in myometrial arteries from women with pre-eclampsia

Cardiac GR and MR: From Development to Pathology

Cardiomyocyte and Vascular Smooth Muscle-Independent 11β-Hydroxysteroid Dehydrogenase 1 Amplifies Infarct Expansion, Hypertrophy, and the Development of Heart Failure After Myocardial Infarction in Male Mice

Cardiovascular risk in women: the impact of hormone replacement therapy and prospects for new therapeutic approaches

Characterization of endothelin receptors mediating contraction of rabbit saphenous vein

Constriction to ETB receptor agonists, BQ-3020 and sarafotoxin s6c, in human resistance and capacitance vessels in vivo.

Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

Deletion of Endothelial Cell Endothelin B Receptors Does Not Affect Blood Pressure or Sensitivity to Salt

Dependence of endotoxin-induced vascular hyporeactivity on extracellular L-arginine.

Development and characterization of rodent cardiac phantoms: comparison with in vivo cardiac imaging

Diesel exhaust particulate induces pulmonary and systemic inflammation in rats without impairing endothelial function ex vivo or in vivo

Differential Effects of Angiotensin II on Cardiac Cell Proliferation and Intramyocardial Perivascular Fibrosis In Vivo

Effect of dexamethasone on the onset and persistence of vascular hyporeactivity induced by E. coli lipopolysaccharide in rats

Effect of endotoxin on circulating cyclic GMP in the rat.

Effects of calcium channel blockade on the aortic intima in spontaneously hypertensive rats

Effects of methylene blue on blood pressure and reactivity to norepinephrine in endotoxemic rats

Endothelial cell-specific ETB receptor knockout: autoradiographic and histological characterisation and crucial role in the clearance of endothelin-1.

Endothelin receptors that modulate contraction of the rat fundus

Endothelin-1[1-31] is Not Elevated in Men with Chronic Heart Failure

Endothelins are potent vasoconstrictors, and much more besides

Endothelium-derived hyperpolarizing factor and potassium use different mechanisms to induce relaxation of human subcutaneous resistance arteries

Endotoxin-induced impairment of vascular reactivity in the pithed rat: role of arachidonic acid metabolites.

Endotoxin-induced impairment of vasodepressor responses in the pithed rat

Enhanced angiogenic capacity of human umbilical vein endothelial cells from women with preeclampsia.

Enhanced monocyte recruitment and delayed alternative macrophage polarization accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice

Enhancement of the hypothermic response of mice to delta-9-tetrahydrocannabinol by subhypothermic doses of chlorpromazine and phentolamine

Evidence that an l-arginine/nitric oxide dependent elevation of tissue cyclic GMP content is involved in depression of vascular reactivity by endotoxin ⬇️

Forearm vasoconstriction to endothelin-1 is mediated by ETA and ETB receptors in vivo in humans

Functional heterogeneity of large and small resistance arteries isolated from biopsies of subcutaneous fat: implications for investigation of vascular pathophysiology.

Getting to the heart of intracellular glucocorticoid regeneration: 11β-HSD1 in the myocardium

Glucocorticoid receptor alters isovolumetric contraction and restrains cardiac fibrosis

High-resolution echocardiography in the assessment of cardiac physiology and disease in preclinical models

Human myocardial pericytes: multipotent mesodermal precursors exhibiting cardiac specificity.

Human urotensin II increases coronary perfusion pressure in the isolated rat heart

Imaging the healing murine myocardial infarct in vivo: ultrasound, magnetic resonance imaging and fluorescence molecular tomography

Immunolocalisation and activity of DDAH I and II in the heart and modification post-myocardial infarction.

Improved heart function follows enhanced inflammatory cell recruitment and angiogenesis in 11betaHSD1-deficient mice post-MI.

In vivo pharmacology of Ro 46-2005, the first synthetic nonpeptide endothelin receptor antagonist: implications for endothelin physiology.

Increased vascular responsiveness to norepinephrine in rats with heart failure is endothelium dependent. Dissociation of basal and stimulated nitric oxide release

Incubation with endotoxin activates the L-arginine pathway in vascular tissue

Inducible but not constitutive production of nitric oxide by vascular smooth muscle cells

Influence of endothelium on induction of the L-arginine-nitric oxide pathway in rat aortas

Influence of scanning frequency and ultrasonic contrast agent on reproducibility of left ventricular measurements in the mouse

Investigation of the endothelin system in experimental heart failure

Investigation of the selectivity of alpha, beta-methylene ATP in inhibiting vascular responses of the rat in vivo and in vitro

Localization and function of ET-1 and ET receptors in small arteries post-myocardial infarction: upregulation of smooth muscle ET(B) receptors that modulate contraction

Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway

Manganese-Enhanced T Mapping in the Myocardium of Normal and Infarcted Hearts

Medroxyprogesterone acetate inhibits the cardioprotective effect of estrogen in experimental ischemia-reperfusion injury

MicroRNA-148b Targets the TGF-β Pathway to Regulate Angiogenesis and Endothelial-to-Mesenchymal Transition during Skin Wound Healing

Nitric oxide and gall-bladder motor function

Oestrogen and the cardiovascular system: the good, the bad and the puzzling.

Oestrogen-mediated cardioprotection following ischaemia and reperfusion is mimicked by an oestrogen receptor (ER)alpha agonist and unaffected by an ER beta antagonist

Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist

Preventing local regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1 enhances angiogenesis

Prolonged effect of a novel S-nitrosated glyco-amino acid in endothelium-denuded rat femoral arteries: potential as a slow release nitric oxide donor drug

Pulmonary diesel particulate increases susceptibility to myocardial ischemia/reperfusion injury via activation of sensory TRPV1 and β1 adrenoreceptors

Regulation of the Myocardial Endothelin System by Angiotensin-II and Losartan

Resident cells of the myocardium: more than spectators in cardiac injury, repair and regeneration

Run for your life: exercise, oxidative stress and the ageing endothelium

Sarafotoxin 6c (S6c) reduces infarct size and preserves mRNA for the ETB receptor in the ischemic/reperfused myocardium of anesthetized rats

Statistical considerations in reporting cardiovascular research

Structural changes and cyclic GMP content of the aorta after calcium antagonism or angiotensin converting enzyme inhibition in renovascular hypertensive rats

Systemic Blockade of the Endothelin-B Receptor Increases Peripheral Vascular Resistance in Healthy Men

Targeting C-reactive protein for the treatment of cardiovascular disease.

The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an 'M2' phenotype in response to Th2 immunologic challenge.

The effect of inhibitors of the L-arginine/nitric oxide pathway on endotoxin-induced loss of vascular responsiveness in anaesthetized rats.