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List of works by Angel Cedazo-Minguez

24(),25-Epoxycholesterol and () overexpression promote midbrain dopaminergic neurogenesis

scientific article published on 17 January 2019

27-Hydroxycholesterol Induces Aberrant Morphology and Synaptic Dysfunction in Hippocampal Neurons

scientific article published on 01 January 2019

27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation.

scientific article published on 17 February 2017

27-hydroxycholesterol mediates negative effects of dietary cholesterol on cognition in mice

scientific article published on 18 October 2014

5-HT1B and other related serotonergic proteins are altered in APPswe mutation.

scientific article

A new metabolomic workflow for early detection of Alzheimer's disease.

scientific article

Activity-regulated cytoskeleton-associated protein in rodent brain is down-regulated by high fat diet in vivo and by 27-hydroxycholesterol in vitro

scientific article published on 23 May 2008

Age-dependent pharmacokinetics and effect of roscovitine on Cdk5 and Erk1/2 in the rat brain

scientific article published on 8 June 2008

Aggregation of the Inflammatory S100A8 Precedes Aβ Plaque Formation in Transgenic APP Mice: Positive Feedback for S100A8 and Aβ Productions.

scientific article published on 30 April 2016

Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer's disease

scientific article

Analysis of chiral amino acids in cerebrospinal fluid samples linked to different stages of Alzheimer disease.

scientific article

Androgen induction of prostate cancer cell invasion is mediated by ezrin.

scientific article published on 26 July 2006

Anthocyanins protect from complex I inhibition and APPswe mutation through modulation of the mitochondrial fission/fusion pathways

scientific article published on 4 August 2016

Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities.

scientific article

Apolipoprotein E and beta A4-amyloid: signals and effects.

scientific article

Apolipoprotein E and β‐amyloid (1–42) regulation of glycogen synthase kinase‐3β ⬇️

scientific article published on December 1, 2003

Apolipoprotein E epsilon4 magnifies lifestyle risks for dementia: a population-based study

scientific article published on 08 February 2008

Apolipoprotein E isoform-specific disruption of phosphoinositide hydrolysis: protection by estrogen and glutathione

scientific article published in August 2001

Apolipoprotein E4 Elicits Lysosomal Cathepsin D Release, Decreased Thioredoxin-1 Levels, and Apoptosis.

scientific article published on 30 December 2016

Apolipoprotein E: a major piece in the Alzheimer's disease puzzle.

scientific article

Association of Platelet Serotonin Levels in Alzheimer's Disease with Clinical and Cerebrospinal Fluid Markers

scientific article published on 4 May 2016

Autoantibodies Toward the Angiotensin 2 Type 1 Receptor: A Novel Autoantibody in Alzheimer's Disease

scientific article published on July 2015

Biomarkers for Alzheimer's disease and other forms of dementia: clinical needs, limitations and future aspects

scientific article published on 29 September 2009

Can LDL cholesterol be too low? Possible risks of extremely low levels

scientific article published on 14 March 2017

Caspase cleavage of exon 9 deleted presenilin-1 is an early event in apoptosis induced by calcium ionophore A 23187 in SH-SY5Y neuroblastoma cells

scientific article

Caspase cleaved presenilin-1 is part of active gamma-secretase complexes

scientific article published on 15 March 2006

Cholesterol 24S-Hydroxylase Overexpression Inhibits the Liver X Receptor (LXR) Pathway by Activating Small Guanosine Triphosphate-Binding Proteins (sGTPases) in Neuronal Cells.

scientific article published on 2 August 2014

Cholinergic hypofunction impairs memory acquisition possibly through hippocampal Arc and BDNF downregulation

scientific article published on 2 June 2010

Chronic airway-induced allergy in mice modifies gene expression in the brain toward insulin resistance and inflammatory responses.

scientific article published on August 2013

Combination of apolipoprotein E4 and high carbohydrate diet reduces hippocampal BDNF and arc levels and impairs memory in young mice.

scientific article published in January 2012

Cross-disease analysis of Alzheimer's disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases

scientific article published on 08 March 2019

Current and emerging avenues for Alzheimer's disease drug targets

scientific article published on 29 August 2019

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

scientific article

Decreased cerebrospinal fluid levels of L-carnitine in non-apolipoprotein E4 carriers at early stages of Alzheimer's disease

scientific article published in January 2014

Decreased levels of guanosine 3', 5'-monophosphate (cGMP) in cerebrospinal fluid (CSF) are associated with cognitive decline and amyloid pathology in Alzheimer's disease

scientific article published in June 2015

Defeating Alzheimer's disease and other dementias: a priority for European science and society

scientific article published on April 2016

Differences in brain cholesterol metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms

scientific article published on 16 January 2012

Effects of apolipoprotein E (apoE) isoforms, beta-amyloid (Abeta) and apoE/Abeta complexes on protein kinase C-alpha (PKC-alpha) translocation and amyloid precursor protein (APP) processing in human SH-SY5Y neuroblastoma cells and fibroblasts

scientific article published on 01 June 2001

Estrogen protects against amyloid-β toxicity by estrogen receptor α-mediated inhibition of Daxx translocation.

scientific article

Evidence for sex difference in the CSF/plasma albumin ratio in ~20 000 patients and 335 healthy volunteers

scientific article published on 27 July 2018

Ezrin mediates c-Myc actions in prostate cancer cell invasion.

scientific article

Gamma-secretase activity of presenilin 1 regulates acetylcholine muscarinic receptor-mediated signal transduction

scientific article published on 18 November 2003

Grey matter and cognitive patterns in cognitive impaired subjects using CSF biomarker cut-offs

scientific article published in January 2012

HPA axis dysregulation associated to apolipoprotein E4 genotype in Alzheimer's disease

scientific article published on January 2010

High cholesterol diet induces tau hyperphosphorylation in apolipoprotein E deficient mice.

scientific article

Impaired long term memory consolidation in transgenic mice overexpressing the human soluble form of IL-1ra in the brain

scientific article

Insufficient resolution response in the hippocampus of a senescence-accelerated mouse model--SAMP8.

scientific article published on 10 June 2014

Insulin deprivation decreases insulin degrading enzyme levels in primary cultured cortical neurons and in the cerebral cortex of rats with streptozotocin-induced diabetes

scientific article published on 01 February 2018

Insulin levels are decreased in the cerebrospinal fluid of women with prodomal Alzheimer's disease.

scientific article published in January 2010

Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system.

scientific article published on 26 September 2012

Intracellular localization of amyloid-β peptide in SH-SY5Y neuroblastoma cells.

scientific article

Involvement of glutaredoxin-1 and thioredoxin-1 in beta-amyloid toxicity and Alzheimer's disease.

scientific article published on 25 November 2005

Is it possible to improve memory function by upregulation of the cholesterol 24S-hydroxylase (CYP46A1) in the brain?

scientific article

Lack of insulin results in reduced seladin-1 expression in primary cultured neurons and in cerebral cortex of STZ-induced diabetic rats.

scientific article published on 14 September 2016

Lithium treatment reverses irradiation-induced changes in rodent neural progenitors and rescues cognition

scientific article published on 14 November 2019

Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation

scientific article published on 15 February 2019

Macroautophagy-generated increase of lysosomal amyloid β-protein mediates oxidant-induced apoptosis of cultured neuroblastoma cells

scientific article published on December 2011

Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.

scientific article

Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk.

scientific article published on 05 August 2016

Nicergoline stimulates protein kinase C mediated alpha-secretase processing of the amyloid precursor protein in cultured human neuroblastoma SH-SY5Y cells

scientific article published on October 1999

Oxidative stress in Alzheimer's disease: why did antioxidant therapy fail?

scientific article published on 05 January 2014

Oxysterols and neurodegenerative diseases.

scientific article published on 25 February 2009

Parkin deficiency disrupts calcium homeostasis by modulating phospholipase C signalling.

scientific article

Parkin-mediated ubiquitination regulates phospholipase C-gamma1.

scientific article

Pathways to Alzheimer's disease

scientific article published on March 2014

Pharmacological Modulations of the Serotonergic System in a Cell-Model of Familial Alzheimer's Disease

scientific article published on 7 May 2016

Plasma cholesterol and risk for late-onset Alzheimer’s disease ⬇️

scientific article published on April 1, 2011

Presenilin dependence of phospholipase C and protein kinase C signaling.

scientific article

Presenilin regulates extracellular regulated kinase (Erk) activity by a protein kinase C alpha dependent mechanism

scientific article

Presenilin-mediated signal transduction

scientific article published on 25 May 2007

Prospective analysis of carotid arterial wall structure in pediatric renal transplants with ambulatory normotension and in treated hypertensive recipients

scientific article published in June 2008

Protein kinase C and amyloid precursor protein processing in skin fibroblasts from sporadic and familial Alzheimer's disease cases

scientific article published on 01 March 1999

Reduction of PINK1 or DJ-1 impair mitochondrial motility in neurites and alter ER-mitochondria contacts

scientific article published on 22 August 2018

Regulation of apolipoprotein E secretion in rat primary hippocampal astrocyte cultures

scientific article published in January 2001

Resistance training does not have an effect on cognition or related serum biomarkers in nonagenarians: a randomized controlled trial.

scientific article

Side chain-oxidized oxysterols regulate the brain renin-angiotensin system through a liver X receptor-dependent mechanism

scientific article published on 31 May 2011

Sildenafil Decreases BACE1 and Cathepsin B Levels and Reduces APP Amyloidogenic Processing in the SAMP8 Mouse

scientific article published on 25 July 2014

Successful therapies for Alzheimer's disease: why so many in animal models and none in humans?

scientific article

Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia.

scientific article published on 22 May 2016

Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons.

scientific article

The composition of polypharmacy: A register-based study of Swedes aged 75 years and older.

scientific article published on 29 March 2018

The presenilin 1 deltaE9 mutation gives enhanced basal phospholipase C activity and a resultant increase in intracellular calcium concentrations

scientific article published on 16 July 2002

Thioredoxin-80 protects against amyloid-beta pathology through autophagic-lysosomal pathway regulation

scientific article published on 13 September 2019

Thioredoxin‐80 is a product of alpha‐secretase cleavage that inhibits amyloid‐beta aggregation and is decreased in Alzheimer's disease brain ⬇️

scientific article published on August 30, 2012

Toward a predictive model of Alzheimer's disease progression using capillary electrophoresis-mass spectrometry metabolomics

scientific article published on 25 September 2012

Toward common mechanisms for risk factors in Alzheimer's syndrome

scientific article published on 19 September 2017

Upregulation of brain renin angiotensin system by 27-hydroxycholesterol in Alzheimer's disease

scientific article published on 01 January 2011

Vitamin D in relation to cognitive impairment, cerebrospinal fluid biomarkers, and brain volumes

scientific article published on 25 February 2014

side-chain-oxidized oxysterols upregulate ACE2 and Mas receptor in rat primary neurons

scientific article published on 6 January 2012

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