List of works - Christopher L. Mendias

A Transgenic tdTomato Rat for Cell Migration and Tissue Engineering Applications

scientific article published on 28 February 2018

Active shortening protects against stretch-induced force deficits in human skeletal muscle

scientific article published on 23 February 2017

Adaptive and innate immune cell responses in tendons and lymph nodes after tendon injury and repair

scientific article published on 16 January 2020

Aging-associated exacerbation in fatty degeneration and infiltration after rotator cuff tear.

scientific article published on 20 June 2013

Anterior cruciate ligament tear induces a sustained loss of muscle fiber force production.

scientific article published on 18 January 2018

Assessment of the Contractile Properties of Permeabilized Skeletal Muscle Fibers.

scientific article

Atrogin-1, MuRF-1, and sarcopenia

scientific article published on 20 July 2012

Changes in circulating biomarkers of muscle atrophy, inflammation, and cartilage turnover in patients undergoing anterior cruciate ligament reconstruction and rehabilitation

scientific article

Changes in macrophage phenotype and induction of epithelial-to-mesenchymal transition genes following acute Achilles tenotomy and repair

scientific article published on 4 April 2014

Changes in muscle fiber contractility and extracellular matrix production during skeletal muscle hypertrophy

scientific article published on 15 December 2016

Changes in skeletal muscle and tendon structure and function following genetic inactivation of myostatin in rats

scientific article published on 25 February 2015

Contractile properties of EDL and soleus muscles of myostatin-deficient mice

scientific article

Decreased specific force and power production of muscle fibers from myostatin-deficient mice are associated with a suppression of protein degradation

scientific article

Elevation in circulating biomarkers of cartilage damage and inflammation in athletes with femoroacetabular impingement

scientific article

Endocranial and masticatory muscle volumes in myostatin-deficient mice

scientific article

Ex Situ Limb Perfusion System to Extend Vascularized Composite Tissue Allograft Survival in Swine.

scientific article

Ex Situ Perfusion of Human Limb Allografts for 24 Hours.

scientific article

Fibroblasts take the centre stage in human skeletal muscle regeneration

scientific article published on 6 June 2017

Haploinsufficiency of myostatin protects against aging-related declines in muscle function and enhances the longevity of mice

scientific article

Hyaluronic acid, HAS1, and HAS2 are significantly upregulated during muscle hypertrophy

scientific article

Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia

scientific article

Inhibition of 5-LOX, COX-1, and COX-2 increases tendon healing and reduces muscle fibrosis and lipid accumulation after rotator cuff repair

scientific article

Inhibition of p38 mitogen-activated protein kinase signaling reduces fibrosis and lipid accumulation after rotator cuff repair

scientific article published on 7 April 2016

Inhibition of platelet-derived growth factor signaling prevents muscle fiber growth during skeletal muscle hypertrophy

scientific article published on 27 January 2017

Inhibition of prolyl 4-hydroxylase decreases muscle fibrosis following chronic rotator cuff tear

scientific article published on January 2017

Insulin-like growth factor 1 signaling in tenocytes is required for adult tendon growth

scientific article published on 16 September 2019

Intrinsic stiffness of extracellular matrix increases with age in skeletal muscles of mice.

scientific article

Local cryotherapy minimally impacts the metabolome and transcriptome of human skeletal muscle

scientific article published on 25 May 2017

MMP inhibition as a potential method to augment the healing of skeletal muscle and tendon extracellular matrix

scientific article published on 02 May 2013

Measurement of Maximum Isometric Force Generated by Permeabilized Skeletal Muscle Fibers

scientific article

Mechanical loading and TGF-β change the expression of multiple miRNAs in tendon fibroblasts

scientific article

Mouse forepaw lumbrical muscles are resistant to age-related declines in force production.

scientific article

Multiomics analysis of the mdx/mTR mouse model of Duchenne muscular dystrophy

scientific article published on 15 July 2020

Muscle fibers are injured at the time of acute and chronic rotator cuff repair

scientific article

Optimal Joint Positions for Manual Isometric Muscle Testing

scientific article

Pathogenesis and Management of Tendinopathies in Sports Medicine.

scientific article

Pharmacological inhibition of myostatin protects against skeletal muscle atrophy and weakness after anterior cruciate ligament tear.

scientific article published on 8 February 2017

Physiological adaptations to resistance training in rats selectively bred for low and high response to aerobic exercise training

scientific article

Physiological loading of tendons induces scleraxis expression in epitenon fibroblasts

scientific article

Platelet-Rich Plasma Activates Proinflammatory Signaling Pathways and Induces Oxidative Stress in Tendon Fibroblasts

scientific article published on 8 July 2016

Postnatal Tendon Growth and Remodeling Requires Platelet-Derived Growth Factor Receptor Signaling

scientific article published on 13 December 2017

Prostaglandin D2 signaling is not involved in the recovery of rat hind limb tendons from injury

scientific article published on 01 November 2019

RE: Talks BJ, Fernquest S, Palmer A, et al. 2019. No Evidence of Systemic Inflammation in Symptomatic Patients With Femoroacetabular Impingement

scientific article published on 22 August 2019

Reduced Myogenic and Increased Adipogenic Differentiation Capacity of Rotator Cuff Muscle Stem Cells

scientific article published on 01 February 2019

Reduced muscle fiber force production and disrupted myofibril architecture in patients with chronic rotator cuff tears

scientific article published on 3 September 2014

Regeneration of Skeletal Muscle After Eccentric Injury

scientific article published on 19 December 2016

Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion

scientific article published in October 2004

Rotator cuff tear reduces muscle fiber specific force production and induces macrophage accumulation and autophagy

scientific article

Sex differences in tendon structure and function

scientific article published on 10 January 2017

Simvastatin reduces fibrosis and protects against muscle weakness after massive rotator cuff tear

scientific article

Single Muscle Fibre Contractility Testing in Rats to Quantify Ischaemic Muscle Damage During Reperfusion Injury

scientific article published on 12 June 2019

Skeletal muscle fiber type-selective effects of acute exercise on insulin-stimulated glucose uptake in insulin-resistant, high-fat-fed rats.

scientific article

Stromal vascular stem cell treatment decreases muscle fibrosis following chronic rotator cuff tear

scientific article published on 30 July 2015

Synergist ablation induces rapid tendon growth through the synthesis of a neotendon matrix

scientific article

T lymphocytes are not required for the development of fatty degeneration after rotator cuff tear

scientific article

TGF-β superfamily signaling in muscle and tendon adaptation to resistance exercise

scientific article

TGF-β1 enhances contractility in engineered skeletal muscle

scientific article

Targeted inhibition of TGF-β results in an initial improvement but long-term deficit in force production after contraction-induced skeletal muscle injury.

scientific article published on 13 June 2013

Tendons of myostatin-deficient mice are small, brittle, and hypocellular

scholarly article

The Effect of Ex Situ Perfusion in a Swine Limb Vascularized Composite Tissue Allograft on Survival up to 24 Hours.

scientific article published in January 2016

The MRL/MpJ Mouse Strain Is Not Protected From Muscle Atrophy and Weakness After Rotator Cuff Tear

scientific article published on 17 November 2019

The aging of elite male athletes: age-related changes in performance and skeletal muscle structure and function.

scientific article

Tissue-engineered tendon constructs for rotator cuff repair in sheep

scientific article published on 28 June 2017

Transforming growth factor-beta induces skeletal muscle atrophy and fibrosis through the induction of atrogin-1 and scleraxis

scientific article published on January 2012

What is the role of systemic conditions and options for manipulation of bone formation and bone resorption in rotator cuff tendon healing and repair?

Widespread diversity in the transcriptomes of functionally divergent limb tendons

scientific article published on 21 February 2020

p38 MAPK signaling in postnatal tendon growth and remodeling

scientific article

List of works by Christopher L. Mendias

A Transgenic tdTomato Rat for Cell Migration and Tissue Engineering Applications

Active shortening protects against stretch-induced force deficits in human skeletal muscle

Adaptive and innate immune cell responses in tendons and lymph nodes after tendon injury and repair

Aging-associated exacerbation in fatty degeneration and infiltration after rotator cuff tear.

Anterior cruciate ligament tear induces a sustained loss of muscle fiber force production.

Assessment of the Contractile Properties of Permeabilized Skeletal Muscle Fibers.

Atrogin-1, MuRF-1, and sarcopenia

Changes in circulating biomarkers of muscle atrophy, inflammation, and cartilage turnover in patients undergoing anterior cruciate ligament reconstruction and rehabilitation

Changes in macrophage phenotype and induction of epithelial-to-mesenchymal transition genes following acute Achilles tenotomy and repair

Changes in muscle fiber contractility and extracellular matrix production during skeletal muscle hypertrophy

Changes in skeletal muscle and tendon structure and function following genetic inactivation of myostatin in rats

Contractile properties of EDL and soleus muscles of myostatin-deficient mice

Decreased specific force and power production of muscle fibers from myostatin-deficient mice are associated with a suppression of protein degradation

Elevation in circulating biomarkers of cartilage damage and inflammation in athletes with femoroacetabular impingement

Endocranial and masticatory muscle volumes in myostatin-deficient mice

Ex Situ Limb Perfusion System to Extend Vascularized Composite Tissue Allograft Survival in Swine.

Ex Situ Perfusion of Human Limb Allografts for 24 Hours.

Fibroblasts take the centre stage in human skeletal muscle regeneration

Haploinsufficiency of myostatin protects against aging-related declines in muscle function and enhances the longevity of mice

Hyaluronic acid, HAS1, and HAS2 are significantly upregulated during muscle hypertrophy

Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia

Inhibition of 5-LOX, COX-1, and COX-2 increases tendon healing and reduces muscle fibrosis and lipid accumulation after rotator cuff repair

Inhibition of p38 mitogen-activated protein kinase signaling reduces fibrosis and lipid accumulation after rotator cuff repair

Inhibition of platelet-derived growth factor signaling prevents muscle fiber growth during skeletal muscle hypertrophy

Inhibition of prolyl 4-hydroxylase decreases muscle fibrosis following chronic rotator cuff tear

Insulin-like growth factor 1 signaling in tenocytes is required for adult tendon growth

Intrinsic stiffness of extracellular matrix increases with age in skeletal muscles of mice.

Local cryotherapy minimally impacts the metabolome and transcriptome of human skeletal muscle

MMP inhibition as a potential method to augment the healing of skeletal muscle and tendon extracellular matrix

Measurement of Maximum Isometric Force Generated by Permeabilized Skeletal Muscle Fibers

Mechanical loading and TGF-β change the expression of multiple miRNAs in tendon fibroblasts

Mouse forepaw lumbrical muscles are resistant to age-related declines in force production.

Multiomics analysis of the mdx/mTR mouse model of Duchenne muscular dystrophy

Muscle fibers are injured at the time of acute and chronic rotator cuff repair

Optimal Joint Positions for Manual Isometric Muscle Testing

Pathogenesis and Management of Tendinopathies in Sports Medicine.

Pharmacological inhibition of myostatin protects against skeletal muscle atrophy and weakness after anterior cruciate ligament tear.

Physiological adaptations to resistance training in rats selectively bred for low and high response to aerobic exercise training

Physiological loading of tendons induces scleraxis expression in epitenon fibroblasts

Platelet-Rich Plasma Activates Proinflammatory Signaling Pathways and Induces Oxidative Stress in Tendon Fibroblasts

Postnatal Tendon Growth and Remodeling Requires Platelet-Derived Growth Factor Receptor Signaling

Prostaglandin D2 signaling is not involved in the recovery of rat hind limb tendons from injury

RE: Talks BJ, Fernquest S, Palmer A, et al. 2019. No Evidence of Systemic Inflammation in Symptomatic Patients With Femoroacetabular Impingement

Reduced Myogenic and Increased Adipogenic Differentiation Capacity of Rotator Cuff Muscle Stem Cells

Reduced muscle fiber force production and disrupted myofibril architecture in patients with chronic rotator cuff tears

Regeneration of Skeletal Muscle After Eccentric Injury

Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion

Rotator cuff tear reduces muscle fiber specific force production and induces macrophage accumulation and autophagy

Sex differences in tendon structure and function

Simvastatin reduces fibrosis and protects against muscle weakness after massive rotator cuff tear

Single Muscle Fibre Contractility Testing in Rats to Quantify Ischaemic Muscle Damage During Reperfusion Injury

Skeletal muscle fiber type-selective effects of acute exercise on insulin-stimulated glucose uptake in insulin-resistant, high-fat-fed rats.

Stromal vascular stem cell treatment decreases muscle fibrosis following chronic rotator cuff tear

Synergist ablation induces rapid tendon growth through the synthesis of a neotendon matrix

T lymphocytes are not required for the development of fatty degeneration after rotator cuff tear

TGF-β superfamily signaling in muscle and tendon adaptation to resistance exercise

TGF-β1 enhances contractility in engineered skeletal muscle

Targeted inhibition of TGF-β results in an initial improvement but long-term deficit in force production after contraction-induced skeletal muscle injury.

Tendons of myostatin-deficient mice are small, brittle, and hypocellular

The Effect of Ex Situ Perfusion in a Swine Limb Vascularized Composite Tissue Allograft on Survival up to 24 Hours.

The MRL/MpJ Mouse Strain Is Not Protected From Muscle Atrophy and Weakness After Rotator Cuff Tear

The aging of elite male athletes: age-related changes in performance and skeletal muscle structure and function.

Tissue-engineered tendon constructs for rotator cuff repair in sheep

Transforming growth factor-beta induces skeletal muscle atrophy and fibrosis through the induction of atrogin-1 and scleraxis

What is the role of systemic conditions and options for manipulation of bone formation and bone resorption in rotator cuff tendon healing and repair?

Widespread diversity in the transcriptomes of functionally divergent limb tendons

p38 MAPK signaling in postnatal tendon growth and remodeling