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List of works by Keir C. Neuman

A heterotrimer model of the complete Microprocessor complex revealed by single-molecule subunit counting

scientific article

A kinetic clutch governs religation by type IB topoisomerases and determines camptothecin sensitivity ⬇️

scientific article published on September 18, 2012

A propagating ATPase gradient drives transport of surface-confined cellular cargo

scientific article

A robust assay to measure DNA topology-dependent protein binding affinity.

scientific article

Bimodal Actions of a Naphthyridone/Aminopiperidine-Based Antibacterial That Targets Gyrase and Topoisomerase IV

scientific article published on 28 October 2019

Biocompatible Fluorescent Nanodiamonds as Multifunctional Optical Probes for Latent Fingerprint Detection

scientific article published on 28 January 2020

Characterization of photodamage to Escherichia coli in optical traps.

scientific article

Chiral discrimination and writhe-dependent relaxation mechanism of human topoisomerase IIα.

scientific article published on 18 March 2013

Comparison of DNA decatenation by Escherichia coli topoisomerase IV and topoisomerase III: implications for non-equilibrium topology simplification ⬇️

scientific article published on March 4, 2013

Direct measurement of DNA bending by type IIA topoisomerases: implications for non-equilibrium topology simplification

scientific article

Direct observation of topoisomerase IA gate dynamics

scientific article published on 26 November 2018

Homology sensing via non-linear amplification of sequence-dependent pausing by RecQ helicase

scientific article published on 29 August 2019

Kinetic Pathway of Torsional DNA Buckling

scientific article published on 31 October 2018

Magnetic tweezers for single-molecule manipulation

scientific article

Measurement of the effective focal shift in an optical trap

scientific article published in June 2005

Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis.

scientific article

Mutational analysis of the helicase-like domain of Thermotoga maritima reverse gyrase

scientific article published on 8 July 2008

Nonlamellar phases induced by the interaction of gramicidin S with lipid bilayers. A possible relationship to membrane-disrupting activity.

scientific article

Optical trapping

scientific article

Pulling on the nascent RNA during transcription does not alter kinetics of elongation or ubiquitous pausing

scientific article published on July 2006

Role of the water-metal ion bridge in mediating interactions between quinolones and Escherichia coli topoisomerase IV.

scientific article

Sequence-resolved detection of pausing by single RNA polymerase molecules.

scientific article published on June 2006

Simultaneous, coincident optical trapping and single-molecule fluorescence

scientific article

Single molecule measurements of DNA helicase activity with magnetic tweezers and t-test based step-finding analysis.

scientific article published on 27 April 2016

Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy

scientific article

Single-molecule measurements of DNA topology and topoisomerases.

scientific article

Single-molecule measurements of topoisomerase activity with magnetic tweezers

scientific article published on 01 January 2011

Single-molecule tracking of collagenase on native type I collagen fibrils reveals degradation mechanism

scientific article

SnapShot: force spectroscopy and single-molecule manipulation

scientific article published in May 2013

SnapShot: single-molecule fluorescence

scientific article published in June 2013

Statistical determination of the step size of molecular motors.

scientific article

Tethered-bead, immune sandwich assay.

scientific article

The HRDC domain of E. coli RecQ helicase controls single-stranded DNA translocation and double-stranded DNA unwinding rates without affecting mechanoenzymatic coupling.

scientific article published on 11 June 2015

The tail that wags the dog: topoisomerase IV ParC C-terminal domain controls strand passage activity through multipartite topology-dependent interactions with DNA.

scientific article

Topoisomerase VI is a chirally-selective, preferential DNA decatenase

scientific article published on 25 January 2022

Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking.

scientific article

Use of divalent metal ions in the DNA cleavage reaction of topoisomerase IV ⬇️

scientific article published on February 7, 2011

Wide-field in vivo background free imaging by selective magnetic modulation of nanodiamond fluorescence

scientific article published on 14 March 2014

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