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List of works by Elgene Lim

A laminin 511 matrix is regulated by TAZ and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells.

scientific article

A new sophistication for breast cancer PDXs

scientific article published on 28 February 2022

A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes.

scientific article

A single-cell and spatially resolved atlas of human breast cancers

scientific article published on 06 September 2021

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

scientific article published on 2 August 2009

Adjuvant chemotherapy in luminal breast cancers.

scientific article published on October 2011

Adjuvant endocrine therapy in women with oestrogen-receptor-positive breast cancer: how should the skeletal and vascular side effects be assessed and managed?

scientific article published on 6 August 2016

Assessment and management of bone health in women with oestrogen receptor-positive breast cancer receiving endocrine therapy: Position statement of the Endocrine Society of Australia, the Australian and New Zealand Bone & Mineral Society, the Austral

article

Attitudes of patients with metastatic cancer towards research biopsies

scientific article published on 6 November 2017

Breast cancer in adolescents and young adults: a review with a focus on biology

scientific article published on September 2013

CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer

scientific article published in November 2016

CDK7-dependent transcriptional addiction in triple-negative breast cancer.

scientific article

Clinical Overview of MDM2/X-Targeted Therapies

scientific article

Computational Screening of Anti-Cancer Drugs Identifies a New BRCA Independent Gene Expression Signature to Predict Breast Cancer Sensitivity to Cisplatin

scientific article published on 13 May 2022

Corrigendum: IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel.

scientific article

Desmoplastic melanoma: comparison of expression of differentiation antigens and cancer testis antigens

scientific article published on 01 August 2006

EMT, cell plasticity and metastasis.

scientific article published in December 2016

Emerging data and future directions for CDK4/6 inhibitor treatment of patients with hormone receptor positive HER2-non-amplified metastatic breast cancer

scientific article published on 01 October 2018

Enhancer-Mediated Oncogenic Function of the Menin Tumor Suppressor in Breast Cancer.

scientific article

Evaluation of FGFR targeting in breast cancer through interrogation of patient-derived models

scientific article published on 03 August 2021

Hormone receptor positive, HER2 negative metastatic breast cancer: Impact of CDK4/6 inhibitors on the current treatment paradigm

scientific article published on 01 October 2018

IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG.

scientific article published on 18 May 2015

IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel.

scientific article

Importance of Breast Cancer Subtype in the Development of Androgen Receptor Directed Therapy

scientific article

IκB kinase ε phosphorylates TRAF2 to promote mammary epithelial cell transformation

scientific article

MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy

scientific article published on 6 November 2015

MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.

scientific article

Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling.

scientific article published on 12 March 2018

Neoadjuvant Interferons: Critical for effective PD-1 based immunotherapy in TNBC.

scientific article published on 28 August 2017

Non-canonical AR activity facilitates endocrine resistance in breast cancer

scientific article published on 01 February 2019

Optimizing the approach to patients with potentially resectable liver metastases from colorectal cancer.

scientific article published on November 2007

Overcoming CDK4/6 inhibitor resistance in ER positive breast cancer

scientific article published on 01 January 2019

PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair.

scientific article

PDEF promotes luminal differentiation and acts as a survival factor for ER-positive breast cancer cells

scientific article published on June 2013

Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor

scientific article

Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells

scientific article

Pushing estrogen receptor around in breast cancer

scientific article

Renewed interest in the progesterone receptor in breast cancer

scientific article published on 22 September 2016

Secreted tumor antigens - immune biomarkers for diagnosis and therapy.

scientific article

Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737

scientific article published on 18 July 2011

Sensitizing HR-proficient cancers to PARP inhibitors

scientific article published on 3 March 2017

Targeting androgen receptor in estrogen receptor-negative breast cancer

scientific article

Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer

scientific article published in Nature Communications

Targeting the androgen receptor in breast cancer

scientific article published on February 2015

The RasGAP gene, RASAL2, is a tumor and metastasis suppressor

scientific article published on September 2013

The impact of ethnicity on efficacy and toxicity of cyclin D kinase 4/6 inhibitors in advanced breast cancer: a meta-analysis

article

The influence of language spoken on colorectal cancer diagnosis and management

scientific article published on 01 July 2006

The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy

scientific article published on 01 July 2017

The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy.

scientific article

The role of MDM2 and MDM4 in breast cancer development and prevention.

scientific article

Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways

scientific article

Vinorelbine Potently Induces Placental Cell Death, Does Not Harm Fertility and is a Potential Treatment for Ectopic Pregnancy.

scientific article published on 2 February 2018

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

scientific article