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List of works by Linda Wordeman

A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells

scientific article

A new model for binding of kinesin 13 to curved microtubule protofilaments

scientific article published on 30 March 2009

A perikinetochoric ring defined by MCAK and Aurora-B as a novel centromere domain

scientific article

A standardized kinesin nomenclature

scientific article

A tethering mechanism controls the processivity and kinetochore-microtubule plus-end enrichment of the kinesin-8 Kif18A.

scientific article

AKAP220 protein organizes signaling elements that impact cell migration.

scientific article published on 2 September 2011

Arf GAPs and molecular motors

scientific article published on 21 April 2017

Aurora B regulates MCAK at the mitotic centromere

scientific article

Breathing down the neck of Unc104.

scientific article published on November 2003

Catalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK.

scientific article

Chemical subdomains within the kinetochore domain of isolated CHO mitotic chromosomes

scientific article published on July 1, 1991

Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B.

scientific article

Corrigendum: The tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation.

scientific article

Direct Functional Interaction of the Kinesin-13 Family Membrane Kinesin-like Protein 2A (Kif2A) and Arf GAP with GTP-binding Protein-like, Ankyrin Repeats and PH Domains1 (AGAP1).

scientific article published on 16 August 2016

Direct functional interaction of the kinesin-13 family member kinesin-like protein 2A (Kif2A) and Arf GAP with GTP-binding protein-like, ankyrin repeats and PH domains 1 (AGAP1)

scientific article published on December 2016

Disruption of CENP antigen function perturbs dynein anchoring to the mitotic kinetochore.

scientific article published in June 1996

Distribution of phosphorylated spindle-associated proteins in the diatom Stephanopyxis turris

scientific article published in January 1989

Divergent microtubule assembly rates after short- versus long-term loss of end-modulating kinesins.

scientific article

GPR124 regulates microtubule assembly, mitotic progression, and glioblastoma cell proliferation

scientific article published on 06 May 2019

GTP-tubulin loves microtubule plus ends but marries the minus ends

scientific article published on 19 August 2019

Gravin is a transitory effector of polo-like kinase 1 during cell division

scientific article published on 11 October 2012

HX-MS2 for high performance conformational analysis of complex protein states

scientific article

In vitro and in vivo analysis of microtubule-destabilizing kinesins

scientific article

In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends

scientific article published on 16 September 2010

Kif18A and chromokinesins confine centromere movements via microtubule growth suppression and spatial control of kinetochore tension

scientific article

Kinesin-2 is a motor for late endosomes and lysosomes

scientific article

Long astral microtubules uncouple mitotic spindles from the cytokinetic furrow

scientific article

MCAK associates with the tips of polymerizing microtubules

scientific article

MCAK is present at centromeres, midspindle and chiasmata and involved in silencing of the spindle assembly checkpoint in mammalian oocytes

scientific article

MCAK, a Kin I kinesin, increases the catastrophe frequency of steady-state HeLa cell microtubules in an ATP-dependent manner in vitro

scientific article

Mass spec studio for integrative structural biology.

scientific article

Microtubule length control, a team sport?

scientific article

Mip1 associates with both the Mps1 kinase and actin, and is required for cell cortex stability and anaphase spindle positioning.

scientific article

Mitosis, microtubule dynamics and the evolution of kinesins.

scientific article published on 20 February 2015

Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.

scientific article published on December 2011

Molecular insight into the regulation and function of MCAK.

scientific article published on 5 May 2016

Nucleotide exchange in dimeric MCAK induces longitudinal and lateral stress at microtubule ends to support depolymerization.

scientific article

Oxidative stress decreases microtubule growth and stability in ventricular myocytes

scientific article

Phosphoregulation and depolymerization-driven movement of the Dam1 complex do not require ring formation

scientific article

Rapid measurement of mitotic spindle orientation in cultured mammalian cells.

scientific article published on January 2014

Reactivation of spindle elongation in vitro is correlated with the phosphorylation of a 205 kd spindle-associated protein

scientific article

Reconstitution and functional analysis of kinetochore subcomplexes

scientific article published on January 2010

Revisiting Actin's role in early centrosome separation

scientific article published on 23 December 2015

Rings, bracelets, sleeves, and chevrons: new structures of kinetochore proteins

scientific article published on August 2007

Roles for focal adhesion kinase (FAK) in blastomere abscission and vesicle trafficking during cleavage in the sea urchin embryo.

scientific article

ST-11: A New Brain-Penetrant Microtubule-Destabilizing Agent with Therapeutic Potential for Glioblastoma Multiforme

scientific article published on 20 June 2016

TIP150 interacts with and targets MCAK at the microtubule plus ends

scientific article

The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion

scientific article

The distribution of cytoplasmic microtubules throughout the cell cycle of the centric diatom Stephanopyxis turris: their role in nuclear migration and positioning the mitotic spindle during cytokinesis.

scientific article

The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.

scientific article

The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment

scientific article

The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends

scientific article published in February 2003

The mechanism, function and regulation of depolymerizing kinesins during mitosis.

scientific article published in October 2004

The role of the kinesin-13 neck in microtubule depolymerization.

scientific article published on 15 August 2006

The tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation.

scientific article

Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.

scientific article

Unconventional Motoring: An Overview of the Kin C and Kin I Kinesins

scientific article published on June 1, 2003

β-tubulin carboxy-terminal tails exhibit isotype-specific effects on microtubule dynamics in human gene-edited cells

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