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List of works by Ann K Daly

5th Anniversary meeting of the European Research Network Pharmacogenetics/Pharmacogenomics. 8-9 December 2011, Utrecht, The Netherlands.

scientific article published in May 2012

A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury

scientific article published on 18 January 2019

A common polymorphism in the ABCB11 gene is associated with advanced fibrosis in hepatitis C but not in non-alcoholic fatty liver disease.

scientific article published in April 2011

A multi-factorial analysis of response to warfarin in a UK prospective cohort

scientific article

A polymorphic CfoI site in exon 6 of the human cytochrome P450 CYP2D6 gene detected by the polymerase chain reaction

article

A randomized trial of genotype-guided dosing of warfarin

scientific article published on 19 November 2013

A rapid genotyping method for the vitamin K epoxide reductase complex subunit 1 (VKORC1) gene

article

A role for the pregnane X receptor in flucloxacillin-induced liver injury.

scientific article published in May 2010

APOE genotype makes a small contribution to warfarin dose requirements.

scientific article published in August 2006

Adaptive dosing approaches to the individualization of 13-cis-retinoic acid (isotretinoin) treatment for children with high-risk neuroblastoma.

scientific article

Altered tropomyosin expression in essential hypertension.

scientific article

An inactive cytochrome P450 CYP2D6 allele containing a deletion and a base substitution

scientific article published on 01 March 1995

Antipsychotic drug-induced movement disorders in schizophrenics in relation to CYP2D6 genotype

scientific article published on 01 January 1997

Are Polymorphisms in Genes Relevant to Drug Disposition Predictors of Susceptibility to Drug-Induced Liver Injury?

scientific article published on 27 December 2016

Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF B signalling pathways

article

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study

scientific article published on 30 December 2016

Association of a tumor necrosis factor promoter polymorphism with susceptibility to alcoholic steatohepatitis

scientific article published in July 1997

Association of metabolic gene polymorphisms with tobacco consumption in healthy controls

scientific article published in June 2004

Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

scientific article published on 01 February 1999

Association of single nucleotide polymorphisms in the interleukin-4 gene and interleukin-4 receptor gene with Crohn's disease in a British population

scientific article published on 01 February 2001

Brief report: genetics of alcoholic cirrhosis-GenomALC multinational study

scientific article

CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6α-hydroxylase activity in human liver microsomes

scientific article published on 01 December 2002

CYP2C9 polymorphism and warfarin dose requirements

scientific article published on April 2002

CYP2D6 and CYP2C19 genotypes of patients with terodiline cardiotoxicity identified through the yellow card system

scientific article published in July 2000

CYP2D6 deficiency, a factor in ecstasy related deaths?

scientific article published on July 2002

CYP2D6 update: revised nomenclature for CYP2D7/2D6 hybrid genes

scientific article published in September 2012

CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan

scientific article published on 01 August 1997

CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation

scientific article published in May 2004

Candidate gene case-control studies.

scientific article

Carriage of the PNPLA3 rs738409 C >G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma.

scientific article published on 6 March 2014

Case definition and phenotype standardization in drug-induced liver injury.

scientific article published on 04 May 2011

Characterisation of a retinoic-acid-binding component from F9 embryonal-carcinoma-cell nuclei

scientific article published on 01 October 1987

Characterization of amoxicillin- and clavulanic acid-specific T cells in patients with amoxicillin-clavulanate-induced liver injury.

scientific article published on 23 July 2015

Characterization of the metabolism of fenretinide by human liver microsomes, cytochrome P450 enzymes and UDP‐glucuronosyltransferases ⬇️

scientific article published on February 1, 2011

Clinical and pharmacogenetic influences on response to hydroxychloroquine in discoid lupus erythematosus: a retrospective cohort study.

scientific article published on 7 July 2011

Common allelic variants of cytochrome P4503A4 and their prevalence in different populations

scientific article published on 01 March 2002

Conference scene: initiatives on future biobanking in pharmacogenomics

scientific article published in July 2009

Contribution of age, body size, and CYP2C9 genotype to anticoagulant response to warfarin

scientific article published in March 2004

Cost-effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs

scientific article published on September 2012

Cyclooxygenase-2 Polymorphisms and Pancreatic Cancer Susceptibility

scientific article published on 01 November 2011

Cytochrome P450 CYP1B1 and catechol O-methyltransferase (COMT) genetic polymorphisms and breast cancer susceptibility in a Turkish population

scientific article published on 21 August 2002

Defining drug response for stratified medicine

scientific article published on 3 November 2016

Development of analytical technology in pharmacogenetic research.

scientific article published on 25 September 2003

Direct-to-consumer pharmacogenomic testing assessed in a US-based study

scientific article published on 01 January 2014

Do multiple cytochrome P450 isoforms contribute to parathion metabolism in man?

scientific article published on 21 March 2003

Drug-induced liver injury: past, present and future.

scientific article published on May 2010

Efavirenz induced acute liver failure requiring liver transplantation in a slow drug metaboliser

scientific article published on 12 June 2013

Endocytosis and Lack of Cytotoxicity of Alkyl-Capped Silicon Quantum Dots Prepared from Porous Silicon.

scientific article published on 25 May 2019

Evaluation of laboratory tests for cirrhosis and for alcohol use, in the context of alcoholic cirrhosis

scientific article

Evidence that a polymorphism within the 3'UTR of glutathione peroxidase 4 is functional and is associated with susceptibility to colorectal cancer

scientific article published on 13 October 2007

Factors Affecting Drug Concentrations and QT Interval During Thioridazine Therapy

scientific article published on 25 April 2007

Family history of cancer and tobacco exposure in index cases of pancreatic ductal adenocarcinoma.

scientific article published on 6 April 2011

Flucloxacillin-induced liver injury.

scientific article published on 29 August 2008

Gene polymorphisms of cellular senescence marker p21 and disease progression in non-alcohol-related fatty liver disease

scientific article

Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study

scientific article published in October 2009

Genetic and epigenetic factors in autoimmune reactions toward cytochrome P4502E1 in alcoholic liver disease.

scientific article published in February 2003

Genetic basis of drug-induced liver injury: present and future

scientific article published on 31 May 2014

Genetic determinants of susceptibility and severity in nonalcoholic fatty liver disease ⬇️

scientific article published on April 1, 2011

Genetic modifiers of non-alcoholic fatty liver disease progression

scientific article

Genetic polymorphism of CYP2D6 and lung cancer risk in African-Americans and Caucasians in Los Angeles County

scientific article

Genetic polymorphism of manganese superoxide dismutase (MnSOD) and breast cancer susceptibility.

scientific article published in January 2005

Genetic polymorphisms affecting drug metabolism: recent advances and clinical aspects.

scientific article published on January 2012

Genetic regulation of warfarin metabolism and response

scientific article

Genetic susceptibility to diclofenac-induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes

scientific article published on 17 November 2006

Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease.

scientific article published in February 2010

Genetic variation of CYP2A6, smoking, and risk of cancer.

scientific article published in March 1999

Genetics of Alcoholic Liver Disease

scientific article

Genome-wide association studies in pharmacogenomics.

scientific article published on April 2010

Genotype-guided dosing of coumarin derivatives: the European pharmacogenetics of anticoagulant therapy (EU-PACT) trial design

scientific article published in October 2009

Genotypes and phenotypes of CYP3A in Bangladeshi population

scientific article

Genotyping for CYP2C9 and VKORC1 alleles by a novel point of care assay with HyBeacon® probes

scientific article published on 29 July 2011

Genotyping for polymorphisms in xenobiotic metabolism as a predictor of disease susceptibility.

scientific article published on November 1994

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

scientific article

HLA-DRB1*16: 01-DQB1*05: 02 is a novel genetic risk factor for flupirtine-induced liver injury

scientific article published on 9 March 2016

Hepatic adducts, circulating antibodies, and cytokine polymorphisms in patients with diclofenac hepatotoxicity

scientific article

Heterozygosity for hereditary hemochromatosis is associated with more fibrosis in chronic hepatitis C.

scientific article published in June 1998

Homozygosity for the Gly-9 variant of the dopamine D3 receptor and risk for tardive dyskinesia in schizophrenic patients.

scientific article published on March 2000

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease.

scientific article published in April 2010

Human Leukocyte Antigen (HLA) Pharmacogenomic Tests: Potential and Pitfalls

scientific article published on 01 February 2014

Human cytochrome P450 (CYP) genes: recommendations for the nomenclature of alleles

scientific article published in February 2000

Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury

scientific article published on August 2010

Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological basis for flucloxacillin-induced liver injury.

scientific article

Impact of cytochrome p450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients.

scientific article published in October 2003

Increased platelet-monocyte aggregation in male claudicants with the Pl(A1/A2) polymorphism of Gp IIb/IIIa

scientific article published on 18 April 2008

Influence of IL-6, COL1A1, and VDR gene polymorphisms on bone mineral density in Crohn's disease

scientific article published on 11 July 2005

Institutional profile: pharmacogenomics research at Newcastle University.

scientific article published in September 2012

Inter-individual variation in DNA damage and base excision repair in young, healthy non-smokers: effects of dietary supplementation and genotype

scientific article published on 19 January 2010

Inter-individual variation in nucleotide excision repair in young adults: effects of age, adiposity, micronutrient supplementation and genotype

scientific article published on 7 October 2008

Interview. Ann K Daly talks to Tarryn Greenberg, Commissioning Editor

scientific article published in November 2008

Is There a Need to Teach Pharmacogenetics?

scientific article published on 01 March 2014

Kinetic Studies on the Major form of Aldehyde Reductase in ox Kidney: a General Kinetic Mechanism to Explain Substrate-Dependent Mechanisms and the Inhibition by Anticonvulsants

scientific article published on 01 January 1986

Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs ⬇️

scientific article published on November 1, 2012

Lung cancer risk in relation to genetic polymorphisms of microsomal epoxide hydrolase among African-Americans and Caucasians in Los Angeles County.

scientific article published on May 2000

Lung cancer risk in relation to nicotinic acetylcholine receptor, CYP2A6 and CYP1A1 genotypes in the Bangladeshi population.

scientific article

Lung cancer risk in relation to the CYP2C9 genetic polymorphism among Caucasians in Los Angeles County ⬇️

scientific article published on October 1, 1997

Meta- and pooled analyses of the effects of glutathione S-transferase M1 polymorphisms and smoking on lung cancer risk

scientific article published in August 2002

Metabolic gene polymorphism frequencies in control populations

scientific article published in December 2001

Minocycline hepatotoxicity: Clinical characterization and identification of HLA-B∗35:02 as a risk factor.

scientific article published on 17 March 2017

Molecular genotyping to predict debrisoquine hydroxylation phenotype

scientific article published on 01 October 1990

Mutant debrisoquine hydroxylation genes in Parkinson's disease

article

N-acetyltransferase (NAT2) polymorphism and breast cancer susceptibility: a lack of association in a case-control study of Turkish population

scientific article

N-acetyltransferase 2 (NAT2) genotype as a risk factor for development of drug-induced liver injury relating to antituberculosis drug treatment in a mixed-ethnicity patient group

article

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

scientific article published on 24 March 2021

No evidence for involvement of the interleukin-10 -592 promoter polymorphism in genetic susceptibility to primary biliary cirrhosis

scientific article published in May 1998

Nomenclature for alleles of the cytochrome P450 oxidoreductase gene

scientific article published on July 2009

Opportunities and limitations: the value of pharmacogenetics in clinical practice.

scientific article published on April 2014

Oral anticoagulation: a critique of recent advances and controversies

scientific article

PNPLA3 Gene Polymorphism Is Associated With Predisposition to and Severity of Alcoholic Liver Disease.

scientific article published on 12 May 2015

Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspective

scientific article published on 06 March 2018

Patatin-like phospholipase domain containing 3: A case in point linking genetic susceptibility for alcoholic and nonalcoholic liver disease

scientific article published on 01 April 2010

Patients benefit from genetics-guided coumarin anticoagulant therapy

scientific article

Pharmacogene expression during progression of metabolic dysfunction-associated steatotic liver disease: Studies on mRNA and protein levels and their relevance to drug treatment

scientific article published in 2024

Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting.

scientific article published on 19 October 2015

Pharmacogenetic-guided dosing of coumarin anticoagulants: algorithms for warfarin, acenocoumarol and phenprocoumon

scientific article

Pharmacogenetics and pharmacogenomics

scientific article published on 01 November 2007

Pharmacogenetics of drug metabolizing enzymes in the United Kingdom population: review of current knowledge and comparison with selected European populations.

scientific article published on 20 March 2015

Pharmacogenetics of oral anticoagulants

scientific article

Pharmacogenetics of tardive dyskinesia: combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly polymorphism

scientific article

Pharmacogenetics of the cytochromes P450.

scientific article

Pharmacogenetics of the major polymorphic metabolizing enzymes.

scientific article

Pharmacogenomics of CYP2C9: Functional and Clinical Considerations

scientific article

Pharmacogenomics of adverse drug reactions

scientific article

Point of care testing for improving risk- benefit ratio of aspirin and warfarin

Polymorphic Variants of Cytochrome P450: Relevance to Cancer and Other Diseases

scientific article published on 11 May 2015

Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics

scientific article published in June 2005

Polymorphism in CYP2C8 is associated with reduced plasma concentrations of repaglinide

scientific article published in October 2003

Polymorphism in the farnesyl diphosphate farnesyl transferase 1 gene and nonalcoholic fatty liver disease severity.

scientific article

Polymorphism of glutathione S-transferase M1 and lung cancer risk among African-Americans and Caucasians in Los Angeles County, California.

scientific article

Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?

scientific article published on 01 February 2001

Polymorphisms in the tropomyosin TPM1 short isoform promoter alter gene expression and are associated with increased risk of metabolic syndrome

scientific article published on 14 January 2010

Polymorphisms of the CYP2D6 gene increase susceptibility to ankylosing spondylitis

article

Pooled analysis and meta-analysis of glutathione S-transferase M1 and bladder cancer: a HuGE review

scientific article (publication date: 15 July 2002)

Poor metabolisers of nicotine and CYP2D6 polymorphism

scientific article published on 01 January 1994

Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics

scientific article

Preempting and preventing drug-induced liver injury ⬇️

scientific article published on 01 August 2010

Purification and properties of cellular retinoic acid-binding protein from neonatal rat skin

scientific article published on 01 May 1988

Quality of life in patients with venous thromboembolism and atrial fibrillation treated with coumarin anticoagulants

scientific article published on 25 April 2015

Recent advances in understanding the molecular basis of polymorphisms in genes encoding cytochrome P450 enzymes.

scientific article

Relationship between acetylator status, smoking, and diet and colorectal cancer risk in the north-east of England

scientific article published in July 1997

Relationship between genotype for the cytochrome P450 CYP2D6 and susceptibility to ankylosing spondylitis and rheumatoid arthritis

scientific article

Relationship of polymorphism in CYP2C9 to genetic susceptibility to diclofenac-induced hepatitis

scientific article published in August 2000

Relevance of CYP2E1 to non-alcoholic fatty liver disease.

scientific article published on January 2013

Relevance of nonsynonymous CYP2C8 polymorphisms to 13-cis retinoic acid and paclitaxel hydroxylation.

scientific article published on 26 April 2010

Reversal of warfarin-induced over-anticoagulation with individualized dosing of oral vitamin K: a pilot study

scientific article published on 30 January 2010

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans

scientific article

Role of polymorphisms in the interleukin-10 gene in determining disease susceptibility and phenotype in inflamatory bowel disease

scientific article published on 01 July 2001

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

scientific article published in April 2001

Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions

scientific article published on 03 July 2019

Significance of the minor cytochrome P450 3A isoforms.

scientific article

Stereoselective cardiotoxic effects of terodiline

scientific article published on 01 July 1996

Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles

scientific article

TM6SF2 as a genetic risk factor for fibrosis

scientific article published on 19 June 2015

TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease

scientific article

TM6SF2: Catch-22 in the Fight Against Nonalcoholic Fatty Liver Disease and Cardiovascular Disease?

scientific article published on 29 January 2015

Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver disease

scientific article published on 4 July 2017

The APOC3 T-455C and C-482T promoter region polymorphisms are not associated with the severity of liver damage independently of PNPLA3 I148M genotype in patients with nonalcoholic fatty liver

scientific article published on 21 July 2011

The Effect of the CYP1A1*2A Allele on Colorectal Cancer Susceptibility in a British Population.

scientific article published on 31 May 2016

The Relationship between PON1 phenotype and PON1-192 genotype in detoxification of three oxons by human liver

scientific article published on 28 November 2006

The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: effect on age of presentation and dependence on alcohol dehydrogenase genotype ⬇️

scientific article published on August 1, 1998

The SOD2 C47T polymorphism influences NAFLD fibrosis severity: Evidence from case-control and intra-familial allele association studies

scientific article published on 12 July 2011

The effect of NAT2 genotype and gender on the metabolism of caffeine in nonsmoking subjects.

scientific article

The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants

scientific article (publication date: October 2001)

The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen

scientific article published on 9 June 2005

The impact of simvastatin on warfarin disposition and dose requirements

scientific article published on 01 June 2006

The phenotype standardization project: improving pharmacogenetic studies of serious adverse drug reactions.

scientific article published on June 2011

The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors

scientific article published on January 2012

The role of individual human cytochromes P450 in drug metabolism and clinical response

scientific article published on December 1, 1992

Transcriptional regulation of PNPLA3 and its impact on susceptibility to nonalcoholic fatty liver Disease (NAFLD) in humans

scientific article published on 13 October 2016

Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis

scientific article published on 01 December 2020

Tumour necrosis factor-a promoter polymorphisms in primary biliary cirrhosis

scientific article published on 01 February 1999

Tumour necrosis factor-alpha gene promoter polymorphism and decreased insulin resistance ⬇️

scientific article published on April 1, 1998

Ultrarapid metabolizers of debrisoquine: Characterization and PCR-based detection of alleles with duplication of the CYP2D6 gene

article

Upstream and coding region CYP2C9 polymorphisms: correlation with warfarin dose and metabolism

scientific article published in December 2004

Using Genome-Wide Association Studies to Identify Genes Important in Serious Adverse Drug Reactions ⬇️

scientific article published on January 1, 2012

VKORC1 and CYP2C9 genotype and patient characteristics explain a large proportion of the variability in warfarin dose requirement among children

scientific article published on 18 October 2011

Valine-alanine manganese superoxide dismutase polymorphism is not associated with alcohol-induced oxidative stress or liver fibrosis

scientific article

Variants in the LGALS9 Gene Are Associated With Development of Liver Disease in Heavy Consumers of Alcohol

scientific article published on 17 November 2015

Variation in induced CYP1A1 levels: relationship to CYP1A1, Ah receptor and GSTM1 polymorphisms

scientific article published on 01 February 2000

Warfarin and celecoxib interaction in the setting of cytochrome P450 (CYP2C9) polymorphism with bleeding complication.

scientific article published on February 2004

Warfarin sensitivity: be aware of genetic influence

scientific article

Weight Loss Decreases Excess Pancreatic Triacylglycerol Specifically in Type 2 Diabetes

scientific article published in December 2015

[31] Cellular retinoic acid-binding protein from neonatal rat skin: Purification and analysis

scientific article published on 01 January 1990

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