List of works - Alain Wagner

2-(Maleimidomethyl)-1,3-Dioxanes (MD): a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation

scientific article published on 9 August 2016

A HTS assay for the detection of organophosphorus nerve agent scavengers

scientific article

A One-Pot Synthesis of (E)-Disubstituted Alkenes by a Bimetallic [Rh–Pd]-Catalyzed Hydrosilylation/Hiyama Cross-Coupling Sequence

scientific article published on 01 January 2007

A chemical labeling strategy for proteomics under nondenaturing conditions

scientific article published on 01 January 2010

Acyl Fluorides: Fast, Efficient, and Versatile Lysine-Based Protein Conjugation via Plug-and-Play Strategy.

scientific article published on 26 April 2017

An efficient procedure for traceless solid-phase synthesis of N,N'-substituted thioureas by thermolytic cleavage of resin-bound dithiocarbamates

scientific article published on 01 January 2000

An in vivo strategy to counteract post-administration anticoagulant activity of azido-Warfarin.

scientific article

An original traceless linker strategy for solid-phase synthesis of N,N',N''-substituted guanidines.

scientific article

Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea

scientific article published on 03 July 2007

Antibody-Oligonucleotide Conjugates as Therapeutic, Imaging, and Detection Agents

scientific article published on 24 July 2019

Arginine-selective bioconjugation with 4-azidophenyl glyoxal: application to the single and dual functionalisation of native antibodies

scientific article published in February 2018

Axially chiral facial amphiphiles with a dihydronaphthopentaphene structure as molecular tweezers for SWNTs

scientific article published in October 2009

Benzyl prolinate derivatives as novel selective KCC2 blockers

scientific article published in March 2010

CBTF: new amine-to-thiol coupling reagent for preparation of antibody conjugates with increased plasma stability.

scientific article

Capillary electrophoresis-inductively coupled plasma-mass spectrometry hyphenation for the determination at the nanogram scale of metal affinities and binding constants of phosphorylated ligands

scientific article published on 31 January 2012

Cationic cyclization of 2-alkenyl-1,3-dithiolanes: diastereoselective synthesis of trans-decalins

scientific article published on 13 April 2011

Cationic polydiacetylene micelles for gene delivery

scientific article published on 27 September 2011

Co-delivery of anti-PLK-1 siRNA and camptothecin by nanometric polydiacetylenic micelles results in a synergistic cell killing

scientific article published on 06 June 2018

Concise synthesis of dihydrochalcones via palladium-catalyzed coupling of aryl halides and 1-aryl-2-propen-1-ols

scientific article published on 01 February 2004

Correction: Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation

scientific article

Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation.

scientific article published on 22 May 2015

Developments in the field of bioorthogonal bond forming reactions-past and present trends.

scientific article published on 09 May 2014

Diastereoselective formal total synthesis of (+/-)-triptolide via a novel cationic cyclization of 2-alkenyl-1,3-dithiolane

scientific article published on 5 July 2010

Directed ortho-metalation, a new insight into organosodium chemistry

scientific article published on 01 January 2002

Dynamic micelles of mannoside glycolipids are more efficient than polymers for inhibiting HIV-1 trans-infection.

scientific article published on 18 October 2013

Expedient synthesis of trifunctional oligoethyleneglycol-amine linkers and their use in the preparation of PEG-based branched platforms

scientific article published on 01 November 2018

Facile introduction of SH group on aromatic substrates via electrophilic substitution reactions

scientific article published on 01 July 2003

Fine-tuning the morphology of self-assembled nanostructures of propargyl ammonium-based amphiphiles

scientific article published on October 2010

First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase

scientific article published on 31 March 2011

From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release

scientific article published on 12 May 2016

Highly stereoselective synthesis of (Z,E)-1-halo-1,3-dienol esters via rearrangement of Fischer chromium chloro-carbenes using microwave irradiation

scientific article published on 19 March 2009

Identification of autoreactive B cells with labeled nucleosomes

scientific article

Kinetic resolution of amines: a highly enantioselective and chemoselective acetylating agent with a unique solvent-induced reversal of stereoselectivity

scientific article published in June 2004

MAPN: First-in-Class Reagent for Kinetically Resolved Thiol-to-Thiol Conjugation.

scientific article published on 3 September 2015

Mannoside Glycolipid Conjugates Display Anti-inflammatory Activity by Inhibition of Toll-like Receptor-4 Mediated Cell Activation.

scientific article

Mild chemo-selective hydration of terminal alkynes catalysed by AgSbF6

scientific article published on 15 November 2011

NaNO2-mediated transformation of aliphatic secondary nitroalkanes into ketones or oximes under neutral, aqueous conditions: how the nitro derivative catalyzes its own transformation

scientific article published on 01 December 2004

Nondenaturing chemical proteomics for protein complex isolation and identification

scientific article published in November 2010

Novel Transformation of Primary Nitroalkanes and Primary Alkyl Bromides to the Corresponding Carboxylic Acids

scientific article published on 01 January 1997

Novel chiral derivatizing isothiocyanate-based agent for the enantiomeric excess determination of amines.

scientific article

Palladium-Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine-Containing Molecules at Room Temperature.

scientific article

Pd(II)-catalyzed cascade Wacker-Heck reaction: chemoselective coupling of two electron-deficient reactants

scientific article published on 01 October 2006

Photopolymerized lipids self-assembly for the solubilization of carbon nanotubes

scientific article published on 01 May 2010

Photopolymerized micelles of diacetylene amphiphile: physical characterization and cell delivery properties.

scientific article

Platinum oxide (PtO(2)): a potent hydrosilylation catalyst

scientific article published on 01 June 2002

Polydiacetylenic nanofibers as new siRNA vehicles for in vitro and in vivo delivery.

scientific article published on 11 January 2018

Polyionic Gels: Efficient Heterogeneous Media for Metal Scavenging and Catalysis

scientific article published on 01 April 2006

Potent anti-muscarinic activity in a novel series of quinuclidine derivatives

scientific article published on 3 November 2005

Redefining the TGR5 triterpenoid binding pocket at the C-3 position

scientific article published on December 2010

Reduction-rebridging strategy for the preparation of ADPN-based antibody-drug conjugates

scientific article published on 20 April 2018

Reinvestigation of the noncatalyzed coupling of aryllithium with haloarene: a novel aromatic nucleophilic substitution pathway.

scientific article

Resin-bound 4H-1,3-oxazine-masked beta-diketones for functionalizing cleavage strategy

scientific article published in September 2004

Rh soaked in polyionic gel: an effective catalyst for dehydrogenative silylation of ketones

scientific article published on 01 December 2006

Sandwich immunoassay as a high-throughput screening method for cross-coupling reactions

scientific article published on 01 October 2005

Selective irreversible chemical tagging of cysteine with 3-arylpropiolonitriles

scientific article published on 16 January 2014

Self-Assembled Nanotubes and Helical Tapes from Diacetylene Nonionic Amphiphiles. Structural Studies before and after Polymerization

scientific article published on 08 September 2011

Semi-covalent surface molecular imprinting of polymers by one-stage mini-emulsion polymerization: glucopyranoside as a model analyte.

scientific article published in June 2009

Spiro Diorthoester (SpiDo), a Human Plasma Stable Acid-Sensitive Cleavable Linker for Lysosomal Release

Stereoselective addition of Grignard reagents to new P-chirogenic N-phosphinoylimines

scientific article published on 15 February 2010

Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes

scientific article published on January 2010

Sydnone-based turn-on fluorogenic probes for no-wash protein labeling and in-cell imaging

scientific article published on 01 April 2019

Synthesis and Kinetic evaluation of an azido analogue of methylerythritol phosphate: a Novel Inhibitor of E. coli YgbP/IspD

scientific article published in Scientific Reports

Synthesis and antioxidant properties of pulvinic acids analogues

scientific article published on 25 September 2010

Synthesis and radioprotective properties of pulvinic acid derivatives.

scientific article published on 18 January 2011

Synthesis of Medium- and Large-Size Rings by Intramolecular Nitrile Oxide Dimerization: An Efficient C-C Bond-Forming Ring-Closing Reaction

scientific article published in October 1999

Synthesis of Novel Mannoside Glycolipid Conjugates for Inhibition of HIV-1 Trans-Infection ⬇️

scientific article published on August 7, 2012

Synthesis of biaryls via decarboxylative Pd-catalyzed cross-coupling reaction

scientific article published on 06 April 2007

Synthesis of pulvinic derivatives via TBAF-mediated regioselective opening of an unsymmetrical monoaromatic pulvinic dilactone

scientific article

Theoretical mechanistic study of the TBD-catalyzed intramolecular aldol reaction of ketoaldehydes

scientific article published in July 2010

Traceless, Solid-Phase Synthesis of Biarylmethane Structures through Pd-Catalyzed Release of Supported Benzylsulfonium Salts We thank Rhône Poulenc Rorer and Rhône Poulenc Agro for financial support

scientific article published on 01 May 2000

Tuning the enantioselective N-acetylation of racemic amines: a spectacular salt effect.

scientific article published in May 2005

Ultrafast Click Chemistry with Fluorosydnones

scientific article published on 25 August 2016

Unprecedented, fully recyclable, solid-supported reagent for the kinetic resolution of racemic amines through enantioselective N-acetylation

scientific article published on 01 June 2005

pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery

scientific article published on 03 November 2016

List of works by Alain Wagner

2-(Maleimidomethyl)-1,3-Dioxanes (MD): a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation

A HTS assay for the detection of organophosphorus nerve agent scavengers

A One-Pot Synthesis of (E)-Disubstituted Alkenes by a Bimetallic [Rh–Pd]-Catalyzed Hydrosilylation/Hiyama Cross-Coupling Sequence

A chemical labeling strategy for proteomics under nondenaturing conditions

Acyl Fluorides: Fast, Efficient, and Versatile Lysine-Based Protein Conjugation via Plug-and-Play Strategy.

An efficient procedure for traceless solid-phase synthesis of N,N'-substituted thioureas by thermolytic cleavage of resin-bound dithiocarbamates

An in vivo strategy to counteract post-administration anticoagulant activity of azido-Warfarin.

An original traceless linker strategy for solid-phase synthesis of N,N',N''-substituted guanidines.

Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea

Antibody-Oligonucleotide Conjugates as Therapeutic, Imaging, and Detection Agents

Arginine-selective bioconjugation with 4-azidophenyl glyoxal: application to the single and dual functionalisation of native antibodies

Axially chiral facial amphiphiles with a dihydronaphthopentaphene structure as molecular tweezers for SWNTs

Benzyl prolinate derivatives as novel selective KCC2 blockers

CBTF: new amine-to-thiol coupling reagent for preparation of antibody conjugates with increased plasma stability.

Capillary electrophoresis-inductively coupled plasma-mass spectrometry hyphenation for the determination at the nanogram scale of metal affinities and binding constants of phosphorylated ligands

Cationic cyclization of 2-alkenyl-1,3-dithiolanes: diastereoselective synthesis of trans-decalins

Cationic polydiacetylene micelles for gene delivery

Co-delivery of anti-PLK-1 siRNA and camptothecin by nanometric polydiacetylenic micelles results in a synergistic cell killing

Concise synthesis of dihydrochalcones via palladium-catalyzed coupling of aryl halides and 1-aryl-2-propen-1-ols

Correction: Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation

Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation.

Developments in the field of bioorthogonal bond forming reactions-past and present trends.

Diastereoselective formal total synthesis of (+/-)-triptolide via a novel cationic cyclization of 2-alkenyl-1,3-dithiolane

Directed ortho-metalation, a new insight into organosodium chemistry

Dynamic micelles of mannoside glycolipids are more efficient than polymers for inhibiting HIV-1 trans-infection.

Expedient synthesis of trifunctional oligoethyleneglycol-amine linkers and their use in the preparation of PEG-based branched platforms

Facile introduction of SH group on aromatic substrates via electrophilic substitution reactions

Fine-tuning the morphology of self-assembled nanostructures of propargyl ammonium-based amphiphiles

First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase

From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release

Highly stereoselective synthesis of (Z,E)-1-halo-1,3-dienol esters via rearrangement of Fischer chromium chloro-carbenes using microwave irradiation

Identification of autoreactive B cells with labeled nucleosomes

Kinetic resolution of amines: a highly enantioselective and chemoselective acetylating agent with a unique solvent-induced reversal of stereoselectivity

MAPN: First-in-Class Reagent for Kinetically Resolved Thiol-to-Thiol Conjugation.

Mannoside Glycolipid Conjugates Display Anti-inflammatory Activity by Inhibition of Toll-like Receptor-4 Mediated Cell Activation.

Mild chemo-selective hydration of terminal alkynes catalysed by AgSbF6

NaNO2-mediated transformation of aliphatic secondary nitroalkanes into ketones or oximes under neutral, aqueous conditions: how the nitro derivative catalyzes its own transformation

Nondenaturing chemical proteomics for protein complex isolation and identification

Novel Transformation of Primary Nitroalkanes and Primary Alkyl Bromides to the Corresponding Carboxylic Acids

Novel chiral derivatizing isothiocyanate-based agent for the enantiomeric excess determination of amines.

Palladium-Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine-Containing Molecules at Room Temperature.

Pd(II)-catalyzed cascade Wacker-Heck reaction: chemoselective coupling of two electron-deficient reactants

Photopolymerized lipids self-assembly for the solubilization of carbon nanotubes

Photopolymerized micelles of diacetylene amphiphile: physical characterization and cell delivery properties.

Platinum oxide (PtO(2)): a potent hydrosilylation catalyst

Polydiacetylenic nanofibers as new siRNA vehicles for in vitro and in vivo delivery.

Polyionic Gels: Efficient Heterogeneous Media for Metal Scavenging and Catalysis

Potent anti-muscarinic activity in a novel series of quinuclidine derivatives

Redefining the TGR5 triterpenoid binding pocket at the C-3 position

Reduction-rebridging strategy for the preparation of ADPN-based antibody-drug conjugates

Reinvestigation of the noncatalyzed coupling of aryllithium with haloarene: a novel aromatic nucleophilic substitution pathway.

Resin-bound 4H-1,3-oxazine-masked beta-diketones for functionalizing cleavage strategy

Rh soaked in polyionic gel: an effective catalyst for dehydrogenative silylation of ketones

Sandwich immunoassay as a high-throughput screening method for cross-coupling reactions

Selective irreversible chemical tagging of cysteine with 3-arylpropiolonitriles

Self-Assembled Nanotubes and Helical Tapes from Diacetylene Nonionic Amphiphiles. Structural Studies before and after Polymerization

Semi-covalent surface molecular imprinting of polymers by one-stage mini-emulsion polymerization: glucopyranoside as a model analyte.

Spiro Diorthoester (SpiDo), a Human Plasma Stable Acid-Sensitive Cleavable Linker for Lysosomal Release

Stereoselective addition of Grignard reagents to new P-chirogenic N-phosphinoylimines

Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes

Sydnone-based turn-on fluorogenic probes for no-wash protein labeling and in-cell imaging

Synthesis and Kinetic evaluation of an azido analogue of methylerythritol phosphate: a Novel Inhibitor of E. coli YgbP/IspD

Synthesis and antioxidant properties of pulvinic acids analogues

Synthesis and radioprotective properties of pulvinic acid derivatives.

Synthesis of Medium- and Large-Size Rings by Intramolecular Nitrile Oxide Dimerization: An Efficient C-C Bond-Forming Ring-Closing Reaction

Synthesis of Novel Mannoside Glycolipid Conjugates for Inhibition of HIV-1 Trans-Infection ⬇️

Synthesis of biaryls via decarboxylative Pd-catalyzed cross-coupling reaction

Synthesis of pulvinic derivatives via TBAF-mediated regioselective opening of an unsymmetrical monoaromatic pulvinic dilactone

Theoretical mechanistic study of the TBD-catalyzed intramolecular aldol reaction of ketoaldehydes

Traceless, Solid-Phase Synthesis of Biarylmethane Structures through Pd-Catalyzed Release of Supported Benzylsulfonium Salts We thank Rhône Poulenc Rorer and Rhône Poulenc Agro for financial support

Tuning the enantioselective N-acetylation of racemic amines: a spectacular salt effect.

Ultrafast Click Chemistry with Fluorosydnones

Unprecedented, fully recyclable, solid-supported reagent for the kinetic resolution of racemic amines through enantioselective N-acetylation

pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery