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List of works by Robin M Hobbs

A genetic platform to model sarcomagenesis from primary adult mesenchymal stem cells

scientific article

Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function

scientific article

Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling.

scientific article published on 17 April 2018

Cyclin-dependent kinase antagonizes promyelocytic leukemia zinc-finger through phosphorylation

scientific article published on 4 February 2008

DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia

scientific article published on 23 May 2019

Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3.

scientific article published on 28 December 2009

Differential requirement of mTOR in postmitotic tissues and tumorigenesis

scientific article

Disruption of PLZP in mice leads to increased T-lymphocyte proliferation, cytokine production, and altered hematopoietic stem cell homeostasis

scientific journal article

Distinct germline progenitor subsets defined through Tsc2-mTORC1 signaling

scientific article

Distinctive molecular features of regenerative stem cells in the damaged male germline

scientific article published on 06 May 2022

Essential role of Plzf in maintenance of spermatogonial stem cells

scientific journal article

Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.

scientific article

Expression of activated MEK1 in differentiating epidermal cells is sufficient to generate hyperproliferative and inflammatory skin lesions

scientific article

GILZ-dependent modulation of mTORC1 regulates spermatogonial maintenance

scientific article published on 18 September 2018

Generation of functional hepatocytes from mouse germ line cell-derived pluripotent stem cells in vitro.

scientific article published on August 2010

Generation of functional multipotent adult stem cells from GPR125+ germline progenitors

scientific article

Germline Stem Cell Activity Is Sustained by SALL4-Dependent Silencing of Distinct Tumor Suppressor Genes.

scientific article

Glucocorticoid-induced leucine zipper (GILZ) regulates testicular FOXO1 activity and spermatogonial stem cell (SSC) function

scientific article

Identification of dynamic undifferentiated cell states within the male germline

scientific article published in Nature Communications

Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation

scientific article

Inpp5e suppresses polycystic kidney disease via inhibition of PI3K/Akt-dependent mTORC1 signaling

scientific article published on 7 April 2016

LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair

scientific article

Mechanisms regulating mammalian spermatogenesis and fertility recovery following germ cell depletion

scientific article published on 28 June 2019

POKEMON Is a Proto-Oncogene Which Plays a Key Role in Lymphomagenesis. ⬇️

scholarly article

Plzf Regulates Germline Progenitor Self-Renewal by Opposing mTORC1 ⬇️

scientific article published on August 6, 2010

RNA processing in the male germline: Mechanisms and implications for fertility

scientific article published on 9 October 2017

Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF.

scientific article published on May 2007

Regulation of interleukin-1alpha expression by integrins and epidermal growth factor receptor in keratinocytes from a mouse model of inflammatory skin disease

scientific article published on 22 March 2003

Reprogramming can be a transforming experience

scientific article published in March 2014

Role of the proto-oncogene Pokemon in cellular transformation and ARF repression

scientific article

SOX3 promotes generation of committed spermatogonia in postnatal mouse testes

scientific article published on 21 April 2020

Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis

scientific article

Systemic elevation of PTEN induces a tumor-suppressive metabolic state

scientific article published on 6 March 2012

The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

scientific article

Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition.

scientific article

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