List of works - Yuhei Nishimura

A high-throughput fluorescence-based assay system for appetite-regulating gene and drug screening

scientific article

Activation of Sterol Regulatory Element Binding Factors by Fenofibrate and Gemfibrozil Stimulates Myelination in Zebrafish.

scientific article published on 11 July 2016

An Integrated In Silico and In Vivo Approach to Identify Protective Effects of Palonosetron in Cisplatin-Induced Nephrotoxicity

scientific article published on 20 December 2020

C3orf70 Is Involved in Neural and Neurobehavioral Development

scientific article published on 16 October 2019

CRISPR-mediated Bmpr2 point mutation exacerbates late pulmonary vasculopathy and reduces survival in rats with experimental pulmonary hypertension

scientific article published on 08 April 2022

Chemokines protect vascular smooth muscle cells from cell death induced by cyclic mechanical stretch

scientific article published on 23 November 2017

Comparative Transcriptome Analysis Identifies CCDC80 as a Novel Gene Associated with Pulmonary Arterial Hypertension

scientific article published on 07 June 2016

DNA Damage Response Is Involved in the Developmental Toxicity of Mebendazole in Zebrafish Retina.

scientific article published on 14 March 2016

Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity

scientific article

Downregulation of GSTK1 Is a Common Mechanism Underlying Hypertrophic Cardiomyopathy.

scientific article published on 14 June 2016

Downregulation of Max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice.

scientific article

Downregulation of stanniocalcin 1 is responsible for sorafenib-induced cardiotoxicity

scientific article published on 3 November 2014

Drug discovery using transcriptome data.

scientific article

E2F4 Promotes Neuronal Regeneration and Functional Recovery after Spinal Cord Injury in Zebrafish

scientific article

E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish

scientific article published on 20 May 2015

EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase.

scientific article published on 22 February 2018

EP300 Protects from Light-Induced Retinopathy in Zebrafish.

scientific article published on 19 May 2016

Editorial: Drug Repositioning: Current Advances and Future Perspectives

scholarly article by Yuhei Nishimura & Hideaki Hara published 2018 in Frontiers in Pharmacology

Establishment of a drug evaluation model against light-induced retinal degeneration using adult pigmented zebrafish

scientific article published on 06 June 2016

Gene Expression Profiles of Human Cerebral Organoids Identify PPAR Pathway and <i>PKM2</i> as Key Markers for Oxygen-Glucose Deprivation and Reoxygenation

scientific article published on 08 June 2021

Generation of a Triple-Transgenic Zebrafish Line for Assessment of Developmental Neurotoxicity during Neuronal Differentiation

scientific article published on 24 September 2019

Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways

scientific article

Genomic organization, chromosomal localization, and alternative splicing of the human phosphodiesterase 8B gene

scientific article (publication date: 11 October 2002)

Green tea extract suppresses adiposity and affects the expression of lipid metabolism genes in diet-induced obese zebrafish

scientific article

Guinea pig cysteinyl leukotriene receptor 2 (gpCysLT2) mediates cell proliferation and intracellular calcium mobilization by LTC4 and LTD4.

scientific article published in February 2008

Heterogeneous dysregulation of microRNAs across the autism spectrum.

scientific article published on 19 June 2008

Identification of a novel indoline derivative for in vivo fluorescent imaging of blood-brain barrier disruption in animal models

scientific article

In Vivo Detection of Mitochondrial Dysfunction Induced by Clinical Drugs and Disease-Associated Genes Using a Novel Dye ZMJ214 in Zebrafish

scientific article published on 2 December 2015

In vivo assessment of the permeability of the blood-brain barrier and blood-retinal barrier to fluorescent indoline derivatives in zebrafish.

scientific article

In vivo imaging of the mouse neurovascular unit under chronic cerebral hypoperfusion

scientific article

In vivo imaging of zebrafish retinal cells using fluorescent coumarin derivatives

scientific article

Increased susceptibility to oxidative stress-induced toxicological evaluation by genetically modified nrf2a-deficient zebrafish

scientific article published on 27 December 2018

Integrated Approaches to Drug Discovery for Oxidative Stress-Related Retinal Diseases.

scientific article published on 7 December 2016

Intermediate filaments and IF-associated proteins: from cell architecture to cell proliferation

scientific article published on 01 January 2019

In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5(3).

scientific article

Molecular cloning of novel mouse and human putative citrate lyase beta-subunit.

scientific article

New photic stimulating system with white light-emitting diodes to elicit electroretinograms from zebrafish larvae.

scientific article published on 29 July 2017

Novel immunologic tolerance of human cancer cell xenotransplants in zebrafish.

scientific article published on 18 December 2015

Novel reciprocal regulation of cAMP signaling and apoptosis by orphan G-protein-coupled receptor GPRC5A gene expression.

scientific article

Overcoming Obstacles to Drug Repositioning in Japan.

scientific article published on 11 October 2017

Oxidative Stress in Retinal Diseases.

scientific article published on 15 March 2017

Pharmacogenomics of cardiovascular pharmacology: pharmacogenomic network of cardiovascular disease models.

scientific article published on May 2008

Pharmacological profiling of zebrafish behavior using chemical and genetic classification of sleep-wake modifiers.

scientific article

Potential protective function of the sterol regulatory element binding factor 1-fatty acid desaturase 1/2 axis in early-stage age-related macular degeneration

scientific article published on 16 March 2017

Potential role for heat shock protein 72 in antagonizing cerebral vasospasm after rat subarachnoid hemorrhage

scientific journal article

Primary Cilia as Signaling Hubs in Health and Disease

scientific article published on 16 November 2018

Quantitative phenotyping-based in vivo chemical screening in a zebrafish model of leukemia stem cell xenotransplantation

scientific article (publication date: 2014)

Repeated Blood Collection for Blood Tests in Adult Zebrafish

scientific article published on 30 August 2015

S-nitrosylation regulates mitochondrial quality control via activation of parkin

scientific article published in January 2013

SEMA4A mutations lead to susceptibility to light irradiation, oxidative stress, and ER stress in retinal pigment epithelial cells.

scientific article

Systems pharmacology of adiposity reveals inhibition of EP300 as a common therapeutic mechanism of caloric restriction and resveratrol for obesity

scientific article

Targeting E3 Ubiquitin Ligases and Deubiquitinases in Ciliopathy and Cancer

scientific article published on 19 August 2020

Tetraploidy in cancer and its possible link to aging

article by Kozo Tanaka et al published 1 September 2018 in Cancer Science

Transcriptional and post-transcriptional regulation of monocyte chemoattractant protein-3 gene expression in human endothelial cells by phorbol ester and cAMP signalling

scientific article published on April 2000

Transcriptome analysis of anti-fatty liver action by Campari tomato using a zebrafish diet-induced obesity model

scientific article published on 13 December 2011

Using zebrafish in drug discovery for nervous system disorders

scientific article published on 01 January 2017

Using zebrafish in systems toxicology for developmental toxicity testing.

scientific article

Zebrafish as a systems toxicology model for developmental neurotoxicity testing

scientific article

Zebrafish beta-adrenergic receptor mRNA expression and control of pigmentation.

scientific article published on 18 June 2009

Zebrafish xenotransplantation model for cancer stem-like cell study and high-throughput screening of inhibitors

scientific article published on 11 September 2014

Zebrafish-based systems pharmacology of cancer metastasis.

scientific article published on January 2014

Zinc finger MYND-type containing 8 promotes tumour angiogenesis via induction of vascular endothelial growth factor-A expression

scientific article published on 10 August 2014

List of works by Yuhei Nishimura

A high-throughput fluorescence-based assay system for appetite-regulating gene and drug screening

Activation of Sterol Regulatory Element Binding Factors by Fenofibrate and Gemfibrozil Stimulates Myelination in Zebrafish.

An Integrated In Silico and In Vivo Approach to Identify Protective Effects of Palonosetron in Cisplatin-Induced Nephrotoxicity

C3orf70 Is Involved in Neural and Neurobehavioral Development

CRISPR-mediated Bmpr2 point mutation exacerbates late pulmonary vasculopathy and reduces survival in rats with experimental pulmonary hypertension

Chemokines protect vascular smooth muscle cells from cell death induced by cyclic mechanical stretch

Comparative Transcriptome Analysis Identifies CCDC80 as a Novel Gene Associated with Pulmonary Arterial Hypertension

DNA Damage Response Is Involved in the Developmental Toxicity of Mebendazole in Zebrafish Retina.

Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity

Downregulation of GSTK1 Is a Common Mechanism Underlying Hypertrophic Cardiomyopathy.

Downregulation of Max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice.

Downregulation of stanniocalcin 1 is responsible for sorafenib-induced cardiotoxicity

Drug discovery using transcriptome data.

E2F4 Promotes Neuronal Regeneration and Functional Recovery after Spinal Cord Injury in Zebrafish

E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish

EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase.

EP300 Protects from Light-Induced Retinopathy in Zebrafish.

Editorial: Drug Repositioning: Current Advances and Future Perspectives

Establishment of a drug evaluation model against light-induced retinal degeneration using adult pigmented zebrafish

Gene Expression Profiles of Human Cerebral Organoids Identify PPAR Pathway and <i>PKM2</i> as Key Markers for Oxygen-Glucose Deprivation and Reoxygenation

Generation of a Triple-Transgenic Zebrafish Line for Assessment of Developmental Neurotoxicity during Neuronal Differentiation

Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways

Genomic organization, chromosomal localization, and alternative splicing of the human phosphodiesterase 8B gene

Green tea extract suppresses adiposity and affects the expression of lipid metabolism genes in diet-induced obese zebrafish

Guinea pig cysteinyl leukotriene receptor 2 (gpCysLT2) mediates cell proliferation and intracellular calcium mobilization by LTC4 and LTD4.

Heterogeneous dysregulation of microRNAs across the autism spectrum.

Identification of a novel indoline derivative for in vivo fluorescent imaging of blood-brain barrier disruption in animal models

In Vivo Detection of Mitochondrial Dysfunction Induced by Clinical Drugs and Disease-Associated Genes Using a Novel Dye ZMJ214 in Zebrafish

In vivo assessment of the permeability of the blood-brain barrier and blood-retinal barrier to fluorescent indoline derivatives in zebrafish.

In vivo imaging of the mouse neurovascular unit under chronic cerebral hypoperfusion

In vivo imaging of zebrafish retinal cells using fluorescent coumarin derivatives

Increased susceptibility to oxidative stress-induced toxicological evaluation by genetically modified nrf2a-deficient zebrafish

Integrated Approaches to Drug Discovery for Oxidative Stress-Related Retinal Diseases.

Intermediate filaments and IF-associated proteins: from cell architecture to cell proliferation

In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5(3).

Molecular cloning of novel mouse and human putative citrate lyase beta-subunit.

New photic stimulating system with white light-emitting diodes to elicit electroretinograms from zebrafish larvae.

Novel immunologic tolerance of human cancer cell xenotransplants in zebrafish.

Novel reciprocal regulation of cAMP signaling and apoptosis by orphan G-protein-coupled receptor GPRC5A gene expression.

Overcoming Obstacles to Drug Repositioning in Japan.

Oxidative Stress in Retinal Diseases.

Pharmacogenomics of cardiovascular pharmacology: pharmacogenomic network of cardiovascular disease models.

Pharmacological profiling of zebrafish behavior using chemical and genetic classification of sleep-wake modifiers.

Potential protective function of the sterol regulatory element binding factor 1-fatty acid desaturase 1/2 axis in early-stage age-related macular degeneration

Potential role for heat shock protein 72 in antagonizing cerebral vasospasm after rat subarachnoid hemorrhage

Primary Cilia as Signaling Hubs in Health and Disease

Quantitative phenotyping-based in vivo chemical screening in a zebrafish model of leukemia stem cell xenotransplantation

Repeated Blood Collection for Blood Tests in Adult Zebrafish

S-nitrosylation regulates mitochondrial quality control via activation of parkin

SEMA4A mutations lead to susceptibility to light irradiation, oxidative stress, and ER stress in retinal pigment epithelial cells.

Systems pharmacology of adiposity reveals inhibition of EP300 as a common therapeutic mechanism of caloric restriction and resveratrol for obesity

Targeting E3 Ubiquitin Ligases and Deubiquitinases in Ciliopathy and Cancer

Tetraploidy in cancer and its possible link to aging

Transcriptional and post-transcriptional regulation of monocyte chemoattractant protein-3 gene expression in human endothelial cells by phorbol ester and cAMP signalling

Transcriptome analysis of anti-fatty liver action by Campari tomato using a zebrafish diet-induced obesity model

Using zebrafish in drug discovery for nervous system disorders

Using zebrafish in systems toxicology for developmental toxicity testing.

Zebrafish as a systems toxicology model for developmental neurotoxicity testing

Zebrafish beta-adrenergic receptor mRNA expression and control of pigmentation.

Zebrafish xenotransplantation model for cancer stem-like cell study and high-throughput screening of inhibitors

Zebrafish-based systems pharmacology of cancer metastasis.

Zinc finger MYND-type containing 8 promotes tumour angiogenesis via induction of vascular endothelial growth factor-A expression