List of works - Abedawn I. Khalaf

2,2,2-Trifluoro-N-(isoquinolin-5-ylmethyl)acetamide ⬇️

scientific article published on December 12, 2009

3-Acetoxycyclohex-4-ene-1,2-dicarboxylic anhydride

scientific article published on 01 June 2000

A detailed binding free energy study of 2 : 1 ligand–DNA complex formation by experiment and simulation

scientific article published on 22 September 2009

A method for the analysis of sugars in biological systems using reductive amination in combination with hydrophilic interaction chromatography and high resolution mass spectrometry

scientific article

A new synthesis of alkene-containing minor-groove binders and essential hydrogen bonding in binding to DNA and in antibacterial activity

scientific article published on 12 March 2009

Amide isosteres in structure-activity studies of antibacterial minor groove binders

scientific article published on 30 August 2011

An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics

scientific article published on 29 March 2016

Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups

scientific article published on 26 October 2007

Crystal structure of N,N-dimethyl-2-[(4-methyl-benz-yl)sulfon-yl]ethanamine

scientific article published on 6 June 2015

DNA Minor Groove Binders-Inspired by Nature.

scientific article published on December 2016

DNA binding of a short lexitropsin

scientific article published in March 2004

DNA sequence recognition by an imidazole-containing isopropyl-substituted thiazole polyamide (thiazotropsin B)

scientific article published on 27 April 2006

DNA sequence recognition by an isopropyl substituted thiazole polyamide

scientific article published on 24 June 2004

Designing anti-inflammatory drugs from parasitic worms: a synthetic small molecule analogue of the Acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis.

scientific article

Distamycin analogues with enhanced lipophilicity: synthesis and antimicrobial activity

scientific article published on April 2004

Evaluation of minor groove binders (MGBs) as novel anti-mycobacterial agents and the effect of using non-ionic surfactant vesicles as a delivery system to improve their efficacy.

scientific article published on 18 September 2017

Four pyrrole derivatives used as building blocks in the synthesis of minor-groove binders.

scientific article published on 27 January 2017

M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: serominic compounds

scientific article published on 2 February 2007

Novel Minor Groove Binders Cure Animal African Trypanosomiasis in an in Vivo Mouse Model

scientific article published on 13 March 2019

On the Specificity of Reactions Catalysed by the Antibody H11

article

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome ⬇️

scientific article published on 11 May 2015

Ranking ligand affinity for the DNA minor groove by experiment and simulation

scientific article

Recognition of the DNA minor groove by thiazotropsin analogues

scientific article

Selective anti-malarial minor groove binders

scientific article published on 13 May 2016

Selective in vitro anti-cancer activity of non-alkylating minor groove binders

scientific article published on 18 July 2019

Short lexitropsin that recognizes the DNA minor groove at 5'-ACTAGT-3': understanding the role of isopropyl-thiazole

scientific article published in September 2004

Small molecule analogues of the immunomodulatory parasitic helminth product ES-62 have anti-allergy properties

scientific article

Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1

scientific article

Synthesis and antimicrobial activity of some netropsin analogues

scientific article published on 6 October 2004

Synthesis of novel DNA binding agents: indole-containing analogues of bis-netropsin

Synthetic analogues of the parasitic worm product ES-62 reduce disease development in in vivo models of lung fibrosis

scientific article published on 23 May 2018

Thiazotropsin aggregation and its relationship to molecular recognition in the DNA minor groove

scientific article published on 25 April 2013

List of works by Abedawn I. Khalaf

2,2,2-Trifluoro-N-(isoquinolin-5-ylmethyl)acetamide ⬇️

3-Acetoxycyclohex-4-ene-1,2-dicarboxylic anhydride

A detailed binding free energy study of 2 : 1 ligand–DNA complex formation by experiment and simulation

A method for the analysis of sugars in biological systems using reductive amination in combination with hydrophilic interaction chromatography and high resolution mass spectrometry

A new synthesis of alkene-containing minor-groove binders and essential hydrogen bonding in binding to DNA and in antibacterial activity

Amide isosteres in structure-activity studies of antibacterial minor groove binders

An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics

Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups

Crystal structure of N,N-dimethyl-2-[(4-methyl-benz-yl)sulfon-yl]ethanamine

DNA Minor Groove Binders-Inspired by Nature.

DNA binding of a short lexitropsin

DNA sequence recognition by an imidazole-containing isopropyl-substituted thiazole polyamide (thiazotropsin B)

DNA sequence recognition by an isopropyl substituted thiazole polyamide

Designing anti-inflammatory drugs from parasitic worms: a synthetic small molecule analogue of the Acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis.

Distamycin analogues with enhanced lipophilicity: synthesis and antimicrobial activity

Evaluation of minor groove binders (MGBs) as novel anti-mycobacterial agents and the effect of using non-ionic surfactant vesicles as a delivery system to improve their efficacy.

Four pyrrole derivatives used as building blocks in the synthesis of minor-groove binders.

M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: serominic compounds

Novel Minor Groove Binders Cure Animal African Trypanosomiasis in an in Vivo Mouse Model

On the Specificity of Reactions Catalysed by the Antibody H11

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome ⬇️

Ranking ligand affinity for the DNA minor groove by experiment and simulation

Recognition of the DNA minor groove by thiazotropsin analogues

Selective anti-malarial minor groove binders

Selective in vitro anti-cancer activity of non-alkylating minor groove binders

Short lexitropsin that recognizes the DNA minor groove at 5'-ACTAGT-3': understanding the role of isopropyl-thiazole

Small molecule analogues of the immunomodulatory parasitic helminth product ES-62 have anti-allergy properties

Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1

Synthesis and antimicrobial activity of some netropsin analogues

Synthesis of novel DNA binding agents: indole-containing analogues of bis-netropsin

Synthetic analogues of the parasitic worm product ES-62 reduce disease development in in vivo models of lung fibrosis

Thiazotropsin aggregation and its relationship to molecular recognition in the DNA minor groove

Unexpected Dealkylation During Nucleophilic Substitution: Synthesis of 2-N,N-Dialkylamino Benzoxazoles and Benzothiazoles