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List of works by Frederic Jaisser

11β-HSD2 SUMOylation Modulates Cortisol-Induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation.

scientific article

A direct relationship between plasma aldosterone and cardiac L-type Ca2+ current in mice

scientific article published on 15 September 2005

Adipocyte Mineralocorticoid Receptor Activation Leads to Metabolic Syndrome and Induction of Prostaglandin D2 Synthase

scientific article published on 11 May 2015

Adipocyte-Specific Mineralocorticoid Receptor Overexpression in Mice Is Associated With Metabolic Syndrome and Vascular Dysfunction: Role of Redox-Sensitive PKG-1 and Rho Kinase

scientific article published on 19 April 2016

Aldosterone Impairs Mitochondrial Function in Human Cardiac Fibroblasts via A-Kinase Anchor Protein 12.

scientific article

Aldosterone Target NGAL (Neutrophil Gelatinase-Associated Lipocalin) Is Involved in Cardiac Remodeling After Myocardial Infarction Through NFκB Pathway.

scientific article

Aldosterone and Vascular Mineralocorticoid Receptors in Murine Endotoxic and Human Septic Shock.

scientific article published on 25 April 2017

Aldosterone and kidney diseases: an emergent paradigm with important clinical implications ⬇️

scientific article published on 08 December 2010

Aldosterone and vascular mineralocorticoid receptors: regulators of ion channels beyond the kidney

scientific article published on 30 December 2013

Aldosterone promotes cardiac endothelial cell proliferation in vivo.

scientific article

Aldosterone, mineralocorticoid receptor, and heart failure.

scientific article published on 18 July 2011

Aldosterone-Specific Activation of Cardiomyocyte Mineralocorticoid Receptor In Vivo

scientific article published on 07 January 2013

Benefit of Mineralocorticoid Receptor Antagonism in AKI: Role of Vascular Smooth Muscle Rac1.

scientific article published on 13 January 2017

Blood pressure and amiloride-sensitive sodium channels in vascular and renal cells

scientific article

Cardiomyocyte Overexpression of Neuronal Nitric Oxide Synthase Delays Transition Toward Heart Failure in Response to Pressure Overload by Preserving Calcium Cycling

scientific article published on 09 June 2008

Cardiomyocyte-specific overexpression of oestrogen receptor β improves survival and cardiac function after myocardial infarction in female and male mice

scientific article published on 25 November 2015

Cardiomyopathy and Response to Enzyme Replacement Therapy in a Male Mouse Model for Fabry Disease ⬇️

scientific article (publication date: 2012)

Central serous chorioretinopathy: Recent findings and new physiopathology hypothesis.

scientific article published on 27 May 2015

Circulating Osteoglycin and NGAL/MMP9 Complex Concentrations Predict 1-Year Major Adverse Cardiovascular Events After Coronary Angiography

article

Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel

scientific journal article

Conditional FKBP12.6 overexpression in mouse cardiac myocytes prevents triggered ventricular tachycardia through specific alterations in excitation-contraction coupling.

scientific article published on 31 March 2008

Conditional glucocorticoid receptor expression in the heart induces atrio-ventricular block

scientific article published on 21 May 2007

Coronary endothelial dysfunction after cardiomyocyte-specific mineralocorticoid receptor overexpression

scientific article published on 25 March 2011

Cross-Talk Between Mineralocorticoid and Angiotensin II Signaling for Cardiac Remodeling

scientific article published on 03 November 2008

Deletion of mineralocorticoid receptors in smooth muscle cells blunts renal vascular resistance following acute cyclosporine administration

scientific article published on 30 September 2015

Differential Proteomics Identifies Reticulocalbin-3 as a Novel Negative Mediator of Collagen Production in Human Cardiac Fibroblasts

scientific article published on 22 September 2017

Differential proteomics reveals S100-A11 as a key factor in aldosterone-induced collagen expression in human cardiac fibroblasts.

scientific article

Differential regulations of AQP4 and Kir4.1 by triamcinolone acetonide and dexamethasone in the healthy and inflamed retina

scientific journal article

Does the colonic H,K-ATPase also act as an Na,K-ATPase?

scientific article published on May 1998

Endothelial Mineralocorticoid Receptors Differentially Contribute to Coronary and Mesenteric Vascular Function Without Modulating Blood Pressure

scientific article

Endothelial cell mineralocorticoid receptors: turning cardiovascular risk factors into cardiovascular dysfunction

scientific article published on 24 February 2014

Endothelial mineralocorticoid receptor activation enhances endothelial protein C receptor and decreases vascular thrombosis in mice

scientific article published on 22 January 2014

Epidermal growth factor receptor mediates the vascular dysfunction but not the remodeling induced by aldosterone/salt.

scientific article

Epithelial sodium channel stiffens the vascular endothelium in vitro and in Liddle mice.

scientific article published on 4 March 2013

Extrarenal effects of aldosterone.

scientific article published on March 2012

Galectin-3 blockade inhibits cardiac inflammation and fibrosis in experimental hyperaldosteronism and hypertension

scientific article published on 03 August 2015

Histone Deacetylase 6-Controlled Hsp90 Acetylation Significantly Alters Mineralocorticoid Receptor Subcellular Dynamics But Not its Transcriptional Activity.

scientific article

Interleukin-33/ST2 system attenuates aldosterone-induced adipogenesis and inflammation

scientific article published on 17 April 2015

Mild ischemic injury leads to long-term alterations in the kidney: amelioration by spironolactone administration

scientific article published on 6 June 2015

Mineralocorticoid Receptor Antagonism: A Promising Therapeutic Approach to Treat Ischemic AKI

scientific article published on 19 March 2016

Mineralocorticoid modulation of cardiac ryanodine receptor activity is associated with downregulation of FK506-binding proteins.

scientific article

Mineralocorticoid receptor activation and blockade: an emerging paradigm in chronic kidney disease.

scientific article published on 16 March 2011

Mineralocorticoid receptor activation and mineralocorticoid receptor antagonist treatment in cardiac and renal diseases.

scientific article published on 3 November 2014

Mineralocorticoid receptor antagonists in kidney transplantation: time to consider?

scientific article published on 17 April 2018

Mineralocorticoid receptor antagonists: a patent evaluation of US20150284376A1

scientific article published on 14 September 2016

Mineralocorticoid receptor is involved in rat and human ocular chorioretinopathy ⬇️

scientific article published on June 11, 2012

Mineralocorticoid receptor modulators: a patent review (2007 - 2012).

scientific article

Molecular signature of mineralocorticoid receptor signaling in cardiomyocytes: from cultured cells to mouse heart

scientific article

More than a simple biomarker: the role of NGAL in cardiovascular and renal diseases

scientific article published on 08 May 2018

Myocardial fibrosis: biomedical research from bench to bedside.

scientific article

Neutrophil Gelatinase-Associated Lipocalin from immune cells is mandatory for aldosterone-induced cardiac remodeling and inflammation.

scientific article published on 28 December 2017

Neutrophil Gelatinase-Associated Lipocalin, a Novel Mineralocorticoid Biotarget, Mediates Vascular Profibrotic Effects of Mineralocorticoids.

scientific article published on 18 May 2015

Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone Protects Against Acute Kidney Injury-Mediated Chronic Kidney Disease: Role of Oxidative Stress

scientific article

Novel transgenic mice for inducible gene overexpression in pancreatic cells define glucocorticoid receptor-mediated regulations of beta cells

scientific article

Pathophysiologic mechanisms in diabetic kidney disease: A focus on current and future therapeutic targets

scientific article published on 01 April 2020

Pathophysiological role of the mineralocorticoid receptor in heart: analysis of conditional transgenic models.

scientific article

Porcine model of progressive cardiac hypertrophy and fibrosis with secondary postcapillary pulmonary hypertension.

scientific article published on 6 October 2017

Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion.

scientific article published on 23 February 2018

Prevention of liver cancer cachexia-induced cardiac wasting and heart failure

scientific article published on 29 August 2013

Rationale of the FIBROTARGETS study designed to identify novel biomarkers of myocardial fibrosis

scientific article

Re-Epithelialization of Pathological Cutaneous Wounds Is Improved by Local Mineralocorticoid Receptor Antagonism

scientific article published in June 2016

Regulatory sequences of the mouse villin gene that efficiently drive transgenic expression in immature and differentiated epithelial cells of small and large intestines

scientific article published on 01 March 1999

Role of beta-subunit domains in the assembly, stable expression, intracellular routing, and functional properties of Na,K-ATPase

scientific article published in November 1998

Role of smooth muscle cell mineralocorticoid receptor in vascular tone.

scientific article published on 30 September 2014

Role of the transmembrane and extracytoplasmic domain of beta subunits in subunit assembly, intracellular transport, and functional expression of Na,K-pumps

scientific article published on December 1993

Safety of Eplerenone for Kidney-Transplant Recipients with Impaired Renal Function and Receiving Cyclosporine A.

scientific article

Searching for new mechanisms of myocardial fibrosis with diagnostic and/or therapeutic potential

scientific article published on 30 June 2015

Simultaneous characterization of metabolic, cardiac, vascular and renal phenotypes of lean and obese SHHF rats

scientific article

Smooth muscle cell mineralocorticoid receptors are mandatory for aldosterone-salt to induce vascular stiffness

scientific article published on 2 December 2013

Steroidal and Novel Non-steroidal Mineralocorticoid Receptor Antagonists in Heart Failure and Cardiorenal Diseases: Comparison at Bench and Bedside

scientific article published on 10 November 2016

Sulfenic Acid Modification of Endothelin B Receptor is Responsible for the Benefit of a Nonsteroidal Mineralocorticoid Receptor Antagonist in Renal Ischemia.

scientific article published on 11 September 2015

Tamoxifen administration routes and dosage for inducible Cre-mediated gene disruption in mouse hearts

scientific article published on 6 November 2009

Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia.

scientific article

Targeting the aldosterone pathway in cardiovascular disease.

scientific article

The Aldosterone-Mineralocorticoid Receptor Pathway Exerts Anti-Inflammatory Effects in Endotoxin-Induced Uveitis ⬇️

scientific article published on November 9, 2012

The Deletion of Endothelial Sodium Channel α (αENaC) Impairs Endothelium-Dependent Vasodilation and Endothelial Barrier Integrity in Endotoxemia in Vivo.

scientific article published on 10 April 2018

The diuretic torasemide does not prevent aldosterone-mediated mineralocorticoid receptor activation in cardiomyocytes

scientific article

The endothelial αENaC contributes to vascular endothelial function in vivo.

scientific article published on 26 September 2017

The epidermal growth factor receptor is involved in angiotensin II but not aldosterone/salt-induced cardiac remodelling

scientific article

The epithelial Na+ channel: a new player in the vasculature.

scientific article published on March 2014

The mineralocorticoid receptor as a novel player in skin biology: beyond the renal horizon?

scientific article

The mineralocorticoid receptor in heart: different effects in different cells

scientific article published on 14 February 2011

The mineralocorticoid receptor is a constitutive nuclear factor in cardiomyocytes due to hyperactive nuclear localization signals.

scientific article published on 19 May 2010

Topical Mineralocorticoid Receptor Blockade Limits Glucocorticoid-Induced Epidermal Atrophy in Human Skin

scientific article published on 10 February 2015

Vascular Smooth Muscle Mineralocorticoid Receptor Contributes to Coronary and Left Ventricular Dysfunction After Myocardial Infarction

scientific article published on 22 February 2016

Vascular and inflammatory mineralocorticoid receptors in kidney disease

scientific article published on 03 October 2019

Vascular dysfunction in obese diabetic db/db mice involves the interplay between aldosterone/mineralocorticoid receptor and Rho kinase signaling.

scientific article published on 13 February 2018

Vascular mineralocorticoid receptor and blood pressure regulation

scientific article published on 28 February 2015

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